Preconditioning period ischemia time. Medical search. Frequent questions

Tourniquet release during the late period of TKR can induce ischaemic-reperfusion injury, eliciting the activation of neutrophils, circulating pro-inflammatory cytokines, and reactive oxygen species [ 2 , 3 ]. (medsci.org)
Methods to either mimic or elicit IPC have been attempted in clinical practice in the area of coronary heart disease in an attempt to limit the injury caused to the heart via ischemia and reperfusion injury. (wikipedia.org)
During the post-disaster search and rescue phase, if rescue personnel hastily remove heavy objects covering the bodies of injured individuals and fail to provide targeted medical care, ischemia-reperfusion injury may be triggered, leading to rhabdomyolysis. (bvsalud.org)
Ischemic preconditioning and anesthetic preconditioning (APC) are reported to decrease myocardial infarct size during ischemia-reperfusion injury. (asahq.org)
Since the shortage of donor organs is a major problem, it is imperative to develop methods capable of preserving organs after significant periods of warm and cold ischaemia, and at the same time minimise the reperfusion injury associated with transplantation. (ucl.ac.uk)
1986 ) described ischemic preconditioning as endogenous cardioprotective mechanisms to limit ischemia/reperfusion injury (IRI) via repeated cycles of brief ischemia/reperfusion. (conditionmed.org)
Ischaemia reperfusion injury (IR-injury) occurs when blood supply to a certain area of the body is blocked, and is subsequently followed by reperfusion. (ljmu.ac.uk)
More specifically, acute exercise might possess the same protective effects against ischaemia-reperfusion injury as IPC. (ljmu.ac.uk)
Ischemia-reperfusion injury after lung transplantation increases risk of late bronchiolitis obliterans syndrome. (jamanetwork.com)
Seibert AF, Haynes J, Taylor A. Ischemia-reperfusion injury in the isolated rat lung: role of flow and endogenous leukocytes. (jamanetwork.com)
Ovechkin AV, Lominadze D, Sedoris KC, Robinson TW, Tyagi SC, Roberts AM. Lung ischemia-reperfusion injury: implications of oxidative stress and platelet-arteriolar wall interactions. (jamanetwork.com)
The extent of reperfusion injury is directly proportional to preservation time in cold storage, and research has shown that with static storage methods, heart storage time will not exceed six hours. (gotomydoctor.com)
2 Paradoxically, reperfusion itself can enlarge the infarct size, by complex mechanisms collectively termed ischemia/reperfusion injury. (dovepress.com)
3 In a previous study, different pharmacological principles that aimed to reduce ischemia/reperfusion injury failed to show effect. (dovepress.com)
Although the mechanism remains elusive, the interest in exploring the therapeutic potential of MSC-Exo has greatly increased after the first report of MSC-Exo ameliorating myocardial ischemia/reperfusion injury in a mouse model 10 . (nature.com)

The second window begins at 24 hours and lasts up to 72 hours after the ischaemia and reperfusion stimulus. (wikipedia.org)
Because of relative simplicity (repeated inflation of MRM2 the cuff around arm or knee) and recognized Celgosivir safety it has end up being the stimulus of preference for evaluating whether preconditioning provides scientific utility. (ecolowood.com)
Ischemic tolerance defines transient resistance to lethal ischemia gained by a prior sublethal noxious stimulus (i.e., preconditioning). (biomedcentral.com)
Danger signal evoked in the brain by the stressing preconditioning stimulus induces complex endogenous protective mechanisms resulting to a latent protective phenotype. (biomedcentral.com)
an early phase occurring instantly and continuing for 3-4 h and a late (or delayed) phase occurring ~12 h after the preconditioning stimulus that may persist to 72 h ( 2 , 3 ). (spandidos-publications.com)

The cAMP analogue 8-Br-cAMP-AM (8-Br) confers marked protection against global ischaemia/reperfusion of isolated perfused heart. (mdpi.com)
Ischaemic preconditioning describes the phenomenon where transient and brief ischaemia confers protection against a subsequent prolonged and injurious period of ischaemia. (medsci.org)
Exposing tissues to brief periods of ischemia confers resistance to subsequent prolonged ischemia (local ischemic preconditioning). (au.dk)

Another endogenous form of cardioprotection, similar to PC but applicable at the time of reperfusion, termed postconditioning (PostC), has been recently described. (eurekaselect.com)
The results imply that the cardioprotection of ischemic preconditioning cannot be explained solely by myocardial glycogen depletion. (utmb.edu)
MSC-mediated cardioprotection from ischemia/reperfusion (I/R) injury has been demonstrated through preconditioning of the cardiac tissue [17]. (mycareerpeer.com)
To provide in vivo evidence that DJ‑1 is involved in the delayed cardioprotection induced by ischemic preconditioning (IPC) against oxidative stress caused by ischemia/reperfusion (I/R), the present study subjected male Sprague‑Dawley rats to IPC (3 cycles of 5‑min coronary occlusion/5‑min reperfusion) 24 h prior to I/R (30‑min coronary occlusion/120‑min reperfusion). (spandidos-publications.com)
Our previous study revealed that hypoxia preconditioning of H9c2 cardiomyocytes significantly increased the de novo synthesis of DJ-1 and induced cardioprotection against prolonged hypoxic injury 24 h later ( 17 ). (spandidos-publications.com)

The role of remote ischemic preconditioning (rIPC) in hypoxia is not yet fully understood. (conditionmed.org)
1993 ) introduced remote ischemic preconditioning (rIPC) as a strategy to limit IRI in an area far from that subject to the preconditioning protocol. (conditionmed.org)
Intriguingly, a systemic protective response can be induced by repeated brief ischemia of a limb (remote ischemic conditioning, RIC). (au.dk)

The capability of family tree contribution in the adult center pursuing ischemia reperfusion (IR) damage. (researchhunt.com)

Desflurane induced a first window of preconditioning which lasted up to two hours after the cessation of the volatile anesthetic. (uni-wuerzburg.de)
Furthermore, desflurane induced a second window of preconditioning, which was detectable after 24 hours and lasted up to 72 hours after administration of the volatile anesthetic. (uni-wuerzburg.de)
Volatile anesthetics (e.g. isoflurane) can induce preconditioning and therefore patients treated with this anesthetic may not be further preconditioned with RIPC 25. (ecolowood.com)
6,7 The mechanism of volatile anesthetic preconditioning (APC), although not fully understood, is believed to share similarities with IPC by activation of adenosine triphosphate (ATP)-sensitive potassium (K ATP ) channels, particularly in the mitochondria. (asahq.org)
Sham group (n = 6), mice underwent same anesthetic and surgical procedures except for ischemia induction. (biomedcentral.com)
Anesthetic preconditioning is mediated by beta-adrenergic signaling. (silverchair.com)

In humans, transient ischemic attacks may be the clinical correlate of preconditioning leading to ischemic tolerance. (biomedcentral.com)
IPC is described as short, transient, and nonlethal ischemia periods and subsequent reperfusion which is performed before IR injury and can protect the kidney against long-term ischemia [ 6 - 8 ]. (hindawi.com)
transient sub-lethal ischemia and/or occlusion-reperfusion inherent of intermittent occlusion of blood flow at rest (RIC) or during exercise (BFRE), constitute the initial stimuli to promote release of molecular signals. (au.dk)

BRIEF periods of sublethal ischemia before prolonged ischemia help to protect the heart against extensive infarction. (asahq.org)
IPC involves single or multiple brief periods of sublethal ischemia, which increase myocardial resistance to a greater subsequent insult. (spandidos-publications.com)

These results collectively indicate the chronicity of oxidative stress and an inadequate antioxidant response after a cerebral hypoxia-ischemia event and have motivated the development of preventive and therapeutic approaches against oxidative stress. (hindawi.com)
One of the primary causes of ARF is ischemia/reperfusion (I/R). Inflammatory process and oxidative stress are thought to be the major mechanisms causing I/R. MK-886 is a potent inhibitor of leukotrienes biosynthesis which may have anti-inflammatory and antioxidant effects through inhibition of polymorphonuclear leukocytes (PMNs) infiltration into renal tissues. (biomedcentral.com)
In mixture with preconditioning using the oxidative tension agent paraquat dichloride (PQ), we present that the family tree contributes to endothelial cells but not really to recently produced cardiomyocytes pursuing IR damage. (researchhunt.com)

To determine the role of NO in the second window of preconditioning we administered the NO-synthase inhibitor L-omega-nitro-arginine (LNA) prior to coronary artery occlusion. (uni-wuerzburg.de)
This group exposed anesthetised open-chest dogs to four periods of 5 minute coronary artery occlusions followed by a 5-minute period of reperfusion before the onset of a 40-minute sustained occlusion of the coronary artery. (wikipedia.org)
OBJECTIVE: This study compares the effects of immediate ischemic preconditioning based on somatosensory evoked potential (SSEP) monitoring with those of cerebrospinal fluid drainage in a model of descending thoracic aorta occlusion in dogs. (scielo.org)
As time from symptom onset (artery occlusion) to reperfusion increases, the myocardium available to salvage decreases, which raises the risk of mortality ( 1 , 2 , 3 , 4 and 5 ). (thoracickey.com)
Many modifying factors may influence the absolute time periods of salvage ability (collaterals, intermittent occlusion, myocardial oxygen consumption, ischemic preconditioning, persistence of residual blood flow, recruitment of collaterals, hibernating). (thoracickey.com)
release signals consist of extracellular vesicle (EV)-derived miRNA released from cells at the origin of ischemia/occlusion that circulates to remote organs. (au.dk)

In the absence of ischemic preconditioning (IPC), MCAO induces a large infarction (ischemia-sensitive phenotype). (biomedcentral.com)
REPERFUSION of the myocardium after sustained ischemia induces myocardial cell necrosis and apoptosis, resulting in increased infarct size despite the restoration of coronary blood flow. (silverchair.com)

We tested the hypothesis that 8-Br is also protective under clinically relevant conditions (regional ischaemia) when applied either before ischemia or at the beginning of reperfusion, and this effect is associated with the mitochondrial permeability transition pore (MPTP). (mdpi.com)
Considering that tourniquet application during TKR is related to ischaemic injury, the organ protective effect of ischaemic preconditioning can have a beneficial role after tourniquet release during TKR. (medsci.org)
Meanwhile, the organ protective effect of ischaemic preconditioning could be induced when the episodic ischaemia is at distant tissues or organs, the concept being termed remote ischaemic preconditioning (RIPC) [ 9 ]. (medsci.org)
The phenomenon of ischemic preconditioning (IPC) describes an endogenous protective mechanism resulting in increased tolerance of tissues against ischemia. (uni-wuerzburg.de)
The aim of the current study was to investigate wether desflurane-induced preconditioning exhibits a biphasic time The phenomenon of ischemic preconditioning (IPC) describes an endogenous protective mechanism resulting in increased tolerance of tissues against ischemia. (uni-wuerzburg.de)
Although the phenomenon of ischaemic preconditioning (IPC) is associated with the desired protective capacity, the necessity of its application before sustained ischaemia limits its clinical potential. (sun.ac.za)
When the lethal ischemic insult is applied onto this latent protective phenotype, a separate set of responses are triggered that constitute ischemia-tolerant phenotype, which strikingly differs from the unprimed or unpreconditioned brain's phenotype (Figure 1 ). (biomedcentral.com)
While a prolonged period of ischaemia is harmful to the bodily tissue, short periods of ischaemia interspersed with short bouts of reperfusion have protective effects. (ljmu.ac.uk)

1 demonstrated the phenomenon in dogs, ischemic preconditioning (IPC) has been shown to occur in every mammalian species in which it has been investigated. (asahq.org)
This phenomenon named as preconditioning (PC) and tolerance has been shown to exist in many organs, most extensively in the heart. (biomedcentral.com)
Ischemic preconditioning (IPC) is an important endogenous adaptive phenomenon first described by Murry et al ( 1 ) in 1986. (spandidos-publications.com)

Our results demonstrate that desflurane-induced preconditioning against myocardial infarction in vivo exhibits a characteristic biphasic time pattern similar to ischemic preconditioning. (uni-wuerzburg.de)
Resting echocar- diographic indicators (systolic dysfunction) may also haveMYOCARDIAL ISCHEMIA VS MYOCARDIAL additive predictive value (above and beyond clinical riskINFARCTION factors) for predicting perioperative myocardial infarction in high-risk patients.Myocardial ischemia is the surrogate that is more often ad- Dynamic postoperative predictors. (fliphtml5.com)

3) to search for novel "pharmacological preconditioning agents" that are capable of selectively activating the HO-1 gene in renal tissues. (ucl.ac.uk)
Quickly, the.Few research have investigated pharmacological preconditioning with Cyclosporine in rat kidneys (16, 17). (gasyblog.com)
Genetic and pharmacological studies have identified aldose reductase, heme oxygenase-1 (HO-1), and Mn-superoxide dismutase (MnSOD) as critical mediators of the antioxidative stress effects of late preconditioning ( 8 - 10 ). (spandidos-publications.com)

In addition to postoperative infectious complications, postoperative myocardial ischemia is increased among patients with DM undergoing cardiac and noncardiac surgery. (medscape.com)
Bloodstream samples had been acquired at 4 h post reperfusion and daily until postoperative day time 5 for full blood count, bloodstream urea nitrogen, creatinine, and electrolytes. (gasyblog.com)
Serum bloodstream urea nitrogen and creatinine peaked on postoperative day time 1 in every groups and returned towards the preoperative amounts towards the end of the analysis on postoperative day time 5. (gasyblog.com)
1, Abril-Junio 2006 pp S62-S66Myocardial ischemia and postoperative management John E. Ellis, M.D.* *University of Chicago Medical Center, Chicago, USAINTRODUCTION PREDICTORS AND PROGNOSISTremendous morbidity remains associated with coronary Demographic predictors (prior probability). (fliphtml5.com)
L'Italientiischemic techniques to decrease the prevalence and sever- et al have derived a multifactorial index derived from bothity of postoperative myocardial ischemia. (fliphtml5.com)

In neonatal hypoxia-ischemia, an increase in reactive oxygen species (ROS) is known to occur in the brain at 96 h after a hypoxic-ischemic episode, to which the antioxidant system responds by increasing the activity of superoxide dismutase (SOD) and catalase (CAT) at postnatal day (PND) 11, which decreases afterward [ 5 ]. (hindawi.com)

the EV-derived miRNAs are able to engage in regulation of protein expression and thereby interfere with cellular degradation in remote tissues suffering from chronic ischemia or inflammation (e.g. myocardial infarct, stroke, ulcerative colitis or muscle metabolism). (au.dk)

In the heart, IPC is an intrinsic process whereby repeated short episodes of ischaemia protect the myocardium against a subsequent ischaemic insult. (wikipedia.org)
Protection of the ischemic myocardium is known to occur as a result of ischemic preconditioning (PC), in which repetitive brief periods of ischemia protect the heart from a subsequent prolong ischemic insult. (eurekaselect.com)
Although the mechanisms of ischemic preconditioning and APC are thought to be similar, it is not known whether the beneficial effects of APC are also reduced in the aged myocardium. (asahq.org)

However, the combined effect of prophylactic zinc administration and therapeutic taurine treatment on intrauterine ischemia- (IUI-) induced cerebral damage remains unknown. (hindawi.com)
Approximately 15% to 20% of newborns affected with HIE die in the postnatal period, and 25% suffer from childhood disabilities such as epilepsy, visual and motor impairment, cerebral palsy, cognitive, and behavioral alterations [ 3 ]. (hindawi.com)
The fate of the brain tissue after focal cerebral ischemia is determined by the degree and duration of ischemia, and even without preconditioning, resident brain cells naturally respond to brain ischemia by mobilizing a host of defences and counter responses to mitigate cell injury and death [ 5 ]. (biomedcentral.com)
In an in vitro model of cerebral ischemia (oxygen glucose deprivation, OGD) we investigated whether erythropoietin (EPO) plays a critical role in ischemic preconditioning. (jneurosci.org)

Ischemic preconditioning shows a characteristic biphasic time course consisting of an early first and a delayed second window of preconditioning separated by a period without cardioprotective effects. (uni-wuerzburg.de)
Asimakis, GK 1996, ' Myocardial glycogen depletion cannot explain the cardioprotective effects of ischemic preconditioning in the rat heart ', Journal of Molecular and Cellular Cardiology , vol. 28, no. 3, pp. 563-570. (utmb.edu)

Volatile anesthetics are able to activate this mechanism of preconditioning. (uni-wuerzburg.de)
The mechanism of ischemic preconditioning remains unknown. (utmb.edu)
The role of glycogen depletion prior to prolonged ischemia was examined as a potential mechanism of ischemic preconditioning. (utmb.edu)
Various noxious stimuli can precondition the brain, presumably through a common mechanism, genomic reprogramming. (biomedcentral.com)
This mechanism is called ischaemic preconditioning (IPC). (ljmu.ac.uk)

Abstract Hepatic ischemia/reperfusion (I/R) injury is a common clinical challenge. (123dok.net)

Remote ischaemic preconditioning (RIPC) is known to minimise IRI in previous studies. (medsci.org)
The application of RIPC into clinical fields is more useful than ischaemic preconditioning because it is easy to apply briefly preceding ischaemia to distant organs such as the limbs. (medsci.org)
preconditioning RIPC) provides generated one of the most scientific interest. (ecolowood.com)
22 analyzed the consequences of double daily RIPC for 300 times (a herculean work) in the recurrence of heart stroke in sufferers with symptomatic atherosclerotic intracranial arterial stenosis. (ecolowood.com)
A problem in both heart and human brain field is normally that some sufferers may be currently preconditioned limiting the result of used RIPC. (ecolowood.com)
0.001, sham vs rIPC), as revealed by the time-group and time difference analysis. (conditionmed.org)
0.001 sham vs. rIPC) at submaximal intensity (70-80% of the total exercise time). (conditionmed.org)

Undifferentiated H9c2 cells were supplemented daily for a period of 6 - 12 days, with varying concentrations of retinoic acid (RA) (10nM, 30nM and 1μM), in standard cell culture medium containing either 1% foetal bovine, or horse serum, in order to stimulate differentiation of the cells into a more cardiac-specific phenotype. (sun.ac.za)
These results indicate that cardiac Hmox1 induction not only prevents heme toxicity, but also regulates the timing and registration of genetic programs for mitochondrial quality control that limit cell death, pathological remodeling, and cardiac fibrosis. (jci.org)
For the initial period, we possess examined the cardiac function of Abcg2 during embryonic advancement and we noticed a daring difference in the cell lineages that Abcg2 contributes to in the embryonic and adult center. (researchhunt.com)
Ischemia in the cardiac muscle results in the loss of energy production and changes in the intracellular ion homeostasis [10]. (mycareerpeer.com)

However, it is not easy to apply ischaemic preconditioning in a clinical setting because brief organ ischaemia should be preceded after real ischaemic time [ 8 ]. (medsci.org)
Compared with fibrinolytic therapy, primary PCI is able to achieve higher rates of TIMI grade 3 flow and infarct artery patency, and lower rates of reinfarction, recurrent ischemia, intracranial hemorrhage, and death in randomized clinical trials ( 5 ). (thoracickey.com)
We here summarize clinical data of all 4 known human VSBV-1 encephalitis cases and describe the distribution of VSBV-1 in different brain areas as determined by real-time reverse transcription PCR (RT-PCR) and immunohistochemical (IHC) analysis in the initial encephalitis cluster. (cdc.gov)
Effect of ischemic time on survival in clinical lung transplantation. (jamanetwork.com)

Ischemic preconditioning (IPC) is an experimental technique for producing resistance to the loss of blood supply, and thus oxygen, to tissues of many types. (wikipedia.org)

Hence for instance brief periods of limb ischemia may protect the brain and heart from later ischemic damage 15-18. (ecolowood.com)

The heart keep beating during the operation period, the change of the heart location and the application of heart holder may influence hemodynamic and oxygen metabolism at different operation stage. (biomedres.info)
During the period of ischaemia, tissue is damaged as a result of lack of oxygen. (ljmu.ac.uk)
Capillary blood flow regulation is extremely important for the optimal function of organs especially in conditions where the oxygen supply is inadequate e.g. during ischemia. (au.dk)
Therefore, it is of great interests to understand how capillary blood flow is regulated and possibly uncover ways to control or optimize capillary blood flow during periods of insufficient oxygen availability. (au.dk)

However, time of day did not correlate significantly with post-ischemic recovery of heart rate x developed pressure (HR x DP) or end-diastolic pressure (EDP) in either the non-conditioned or preconditioned hearts. (utmb.edu)

However, whether the increase in DJ-1 expression mediates protection against ischemia/reperfusion (I/R) injury in vivo during the late phase of IPC remains to be determined. (spandidos-publications.com)

coronary artery bypass graft operation has been shown to be a safe and feasible procedure with the potential benefits of reduced operative bleeding and myocardial damage without prolonging intraoperative support or total operating time. (medicus.ru)
8-11 Volatile anesthetics are now being investigated as pharmacologic agents to precondition the heart during coronary artery bypass surgery, with both positive 12-14 and negative 15 results. (asahq.org)
Primary percutaneous coronary intervention (PCI) is the preferred method of reperfusion if this can be performed within recommended time frames. (dovepress.com)

A total of 24 Adult males of Swiss albino mice were randomized to four groups: I/R group (n = 6), mice underwent 30 minute bilateral renal ischemia and 48 hr reperfusion. (biomedcentral.com)
In two models of partial renal IR with and without ischemia preconditioning (IPC) and using Mas receptor (MasR) blockade, A779 or its vehicle, the renal vascular responses to angiotensin II (Ang II) administration in two-kidney-one-clip (2K1C) hypertensive rats were determined. (hindawi.com)
Kidney partial ischemia-reperfusion (IR) injury is defined as a reduction of the renal blood flow (RBF) followed by the recovery of RBF and reoxygenation [ 1 ]. (hindawi.com)

If the blood supply to an organ or a tissue is impaired for a short time (usually less than five minutes) then restored so that blood flow is resumed, and the process repeated two or more times, the cells downstream of the tissue or organ are robustly protected from a final ischemic insult when the blood supply is cut off entirely and permanently. (wikipedia.org)
In liver transplantation, tissue damage at reperfusion is mostly correlated with warm and cold ischemia times and leads in turn to poor graft function [13] and biliary complications [14,15]. (123dok.net)

20 analyzed the result of remote control ischemic preconditioning in ischemic heart stroke patients going through thrombolysis. (ecolowood.com)

Subsequently, a cascade of signaling events initiated by the preconditioning stress establishes delayed protection. (jneurosci.org)

Our results also demonstrate that the difference in the regularity of BFOs between original SBF signal and phase-randomized surrogate time series was larger in ASCI and AB compared to SSCI. (bvsalud.org)

The severity of these disabilities depends on the ischemia duration, damage expansion, and the affected brain region. (hindawi.com)
The most severe cerebrospinal fluid and histologic changes occurred in the patient with the highest viral load, shortest duration of disease, and most medical preconditions. (cdc.gov)

Mortality rates in diabetic patients have been estimated to be up to 5 times greater than in nondiabetic patients, often related to the end-organ damage caused by the disease. (medscape.com)
Six hours following the induction of mind loss of life, German landrace donor pigs (33.2 3.9 kg) were randomly preconditioned with either Cyclosporine (= 9) or Everolimus (= 9) administered via nasogastric tube having a repeated dose right before organ procurement. (gasyblog.com)
Ischemia-reperfusion (I/R) injury is a process whereby parenchymal damage caused by blood flow deprivation is accentuated upon organ reperfusion. (123dok.net)
The time an organ can remain outside the body plays a crucial role in the organ transplantation system. (gotomydoctor.com)

Our results establish EPO as an important paracrine neuroprotective mediator of ischemic preconditioning. (jneurosci.org)

Hypoxic-ischemic encephalopathy (HIE) following intrauterine ischemia (IUI) is one of the leading causes of brain injury in neonates, and the effects can endure until adulthood [ 1 , 2 ]. (hindawi.com)
Partial kidney ischemia-reperfusion (IR) injury is the principal cause of acute kidney injury. (hindawi.com)
de Perrot M, Liu M, Waddell TK, Keshavjee S. Ischemia-reperfusion-induced lung injury. (jamanetwork.com)
Current methods of cold static storage have reached their limits in storage time due to the extent of ischemia-reperfusion (I/R) injury induced during static cold storage. (gotomydoctor.com)

The Ischemic Preconditioning Group (IPC) underwent ischemic preconditioning (n=6) and the Drainage Group underwent cerebrospinal fluid drainage (n=6), immediately before aortic cross-clamping. (scielo.org)
The rats in the IR group underwent 45 min partial kidney ischemia, and the animals in the IPC + IR group underwent two 5 min cycles of partial kidney ischemia followed by 10 min reperfusion and partial kidney ischemia for 45 min. (hindawi.com)

Heart Healthy living i.e. attention to lipid control is less frequent than in the general population ~25% of the patients in Methadone Maintenance Programs use cocaine, which is highly ischemogenic, one or more times a year. (wikipedia.org)
embryonic day time (elizabeth)8.5 in mouse advancement, is indicated in the yolk sac and the heart pipe. (researchhunt.com)

Influence of graft ischemia time on outcomes following lung transplantation. (jamanetwork.com)
Effect of donor age and ischemic time on intermediate survival and morbidity after lung transplantation. (jamanetwork.com)
Graft ischemic time and outcome of lung transplantation: a multicenter analysis. (jamanetwork.com)

Interestingly, a significant and strong correlation was found in finish time between acute IPC and 24-IPC, suggesting comparable effects of IPC and 24-IPC on exercise performance. (ljmu.ac.uk)

The first lasts between 4-6 hours and has been named classical or early preconditioning. (wikipedia.org)

Looking forward, we think time-dependent analyses will be helpful to examine the temporal relationship between hypoglycemia and cardiovascular outcomes, which could shed light on hypoglycemia's contribution to CV risk. (closeconcerns.com)

CONCLUSION: Cerebrospinal fluid drainage and immediate ischemic preconditioning seems to protect the spinal cord during descending thoracic aorta cross-clamping. (scielo.org)
Cerebrospinal fluid analyses over time demonstrated increasing protein concentrations and cell counts, paralleled by pathologic lactate elevations in all patients. (cdc.gov)
We focus on the characterization of the central nervous system (CNS) immunologic response to VSBV-1 by IHC analyses of immune cells in the brain of all patients, as well as by examination of cerebrospinal fluid (CSF) reactions over time during the disease. (cdc.gov)

Long term studies are had a need to additional delineate the part of dental donor preconditioning against ischemia-reperfusion damage. (gasyblog.com)
Rapid reperfusion is mandatory, but unfortunately causes damage in addition to the damage induced by ischaemia alone. (ljmu.ac.uk)
Ischemia preconditioning (IPC) against IR also was recognized as a process to minimize the kidney damage caused by IR [ 5 ]. (hindawi.com)

However, the beneficial effects of ischemic preconditioning have been shown to decrease with advancing age. (asahq.org)
Some effects of H2S protection require the continued presence of H2S, such as ROS scavenging during ischemia. (gotomydoctor.com)

Anatomy38

Organisms11

Diseases47

Chemicals and Drugs49

Analytical, Diagnostic and Therapeutic Techniques and Equipment72

Phenomena and Processes36

Disciplines and Occupations2

Technology, Industry, Agriculture1

Information Science2

Named Groups2

Health Care20

Reperfusion injury15

Stimulus5

Confers3

Cardioprotection5

Remote ischemic3

Pursuing ischemia reperfusion1

Anesthetic6

Transient3

Sublethal ischemia2

Oxidative3

Occlusion6

Induces2

Protective8

Phenomenon3

Infarction2

Pharmacological3

Postoperative5

Hypoxia1

Myocardial infarct1

Myocardium3

Cerebral4

Cardioprotective effects2

Mechanism5

Abstract1

RIPC7

Cardiac4

Clinical4

Resistance1

Limb1

Oxygen4

Correlate1

Vivo1

Coronary3

Renal3

Tissue2

Thrombolysis1

Subsequently1

Surrogate1

Duration2

Organ4

Mediator1

Injury4

Underwent2

Heart2

Transplantation3

Acute1

Lasts1

Outcomes1

Cerebrospinal3

Damage3

Effects2