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  • pp125
  • We found that the alpha(4) tail, paxillin, and FAT, the focal adhesion targeting domain of pp125(FAK), could form a ternary complex and that the alpha(4)-binding paxillin fragment, P(Ala(176)-Asp(275)), specifically blocked paxillin binding to the alpha(4) tail more efficiently than it blocked binding to FAT. (nih.gov)
  • proteins
  • Given the evidences that intgrins trnasmit signals by binding to cytoskeltal proteins and forming mocal adhesion, talin, one of these cytoskeltal proteins which can binds to cytoplasmic domain of integrin beta chian were observed by Adherent Cell Analyzing System (ACAS) equipped with confocal optical system. (nii.ac.jp)
  • expression
  • Ishida, K., Nagahara, H. and Kogiso, T. (2003) Cell adhesion aside from integrin system can abrogate anoikis in rat liver cells by down-regulation of FasL expression, not by activation of PI-3K/Akt and ERK signaling pathway. (scirp.org)
  • Publications] Takeuchi, T, et al: 'Expression of cell adhesion molecules in the salivary and lacrimal glands of sgogren's syndrome' J Clin hab Invest. (nii.ac.jp)
  • interaction
  • Coincident with this agonist-stimulated interaction, MURF1 blocks PKCĪµ translocation to focal adhesions, which is a critical event in the hypertrophic signaling cascade. (rupress.org)