StartleApoptosisInhibitionAMPALocomotorBlockadeInsulinEffectsCurrentsPeptideEffectResponsesMechanismFindingsReceptorCancerCellJournalNoiseReleaseAcuteTemozolomideAnxiolyticMorphineInflammationOpioidCytotoxicityEffectsTumorAntioxidantImmune responseActivityMethodsTreatmentDrugsCommonStudyActivationSuggestHealthDetermine
Startle4
  • Third, infusions of similar doses of pentagastrin into the striatum or nucleus accumbens did not potentiate startle responses. (jneurosci.org)
  • Finally, intra-amygdala infusion of the CCK B receptor-selective antagonist PD-135158 (10 μg) blocked the potentiation of startle produced by i.c.v. infusions of pentagastrin, suggesting that i.c.v. infusions of pentagastrin potentiate startle responses via activation of amygdala CCK B receptors. (jneurosci.org)
  • anxiolytic drugs block fear-potentiated startle in rats. (jneurosci.org)
  • 5HT(3) antagonism abolishes the emotion potentiated startle effect in humans. (ox.ac.uk)
Apoptosis1
  • Finally, Mcl-1 knockout MEFs are extremely sensitive to Bak conformational change and apoptosis induced by ABT-737, effects that are not potentiated by roscovitine. (aacrjournals.org)
Inhibition1
  • Thus, PD potentiated proliferative inhibition and apoptotic induction of both AKT inhibitor and siRNA. (edu.hk)
AMPA3
  • In particular, cyclothiazide greatly potentiates AMPA receptor-mediated depolarizing responses in the hippocampus. (nih.gov)
  • We report that 1-BCP, like cyclothiazide, selectively potentiates AMPA-induced [3H]NE release. (nih.gov)
  • What does potentiated AMPA/NMDA ratio mean? (grantome.com)
Locomotor1
  • Methysergide, which had no effect on its own, significantly potentiated the locomotor hyperactivity produced by MDMA but not amphetamine. (erowid.org)
Blockade1
  • Aptamer targeted therapy potentiates immune checkpoint blockade in triple-negative breast cancer. (cnr.it)
Insulin1
  • Insulin potentiates the transactivation potency of the glucocorticoid receptor. (shengsci.com)
Effects6
  • Factors determining whether cocaine will potentiate the cardiac effects of neurally released norepinephrine. (aspetjournals.org)
  • Scholars@Duke publication: Low-dose fractionated radiation potentiates the effects of cisplatin independent of the hyper-radiation sensitivity in human lung cancer cells. (duke.edu)
  • In this study, the role of hyper-radiation sensitivity (HRS) in potentiating the effects of cisplatin by low-dose fractionated radiation (LDFRT) was evaluated in four human non-small cell lung cancer cell lines. (duke.edu)
  • Recombinant human alpha fetoprotein synergistically potentiates the anti-cancer effects of 1'-S-1'-acetoxychavicol acetate when used as a complex against. (oncotarget.com)
  • Dosing, the importance of vein colour and strain, avoiding side effects, avoiding tolerance, potentiating kratom, and I will close by telling you the single most important thing you can do to ensure a consistently positive experience using kratom. (nootropicsjunkie.com)
  • NPY potentiates sympathetic nerve vasoconstrictive effects. (cdc.gov)
Currents1
  • We demonstrate for the first time at the cellular level that heat-activated ionic currents were potentiated after exposure to the cAMP activator forskolin in rat nociceptive neurons. (jneurosci.org)
Peptide1
  • Molecular mechanism by which spider-driving peptide potentiates coagulation factors. (bvsalud.org)
Effect6
  • The enzyme beta glucuronidase appears to potentiate the desensitizing effect of a small dose of allergen. (wikipedia.org)
  • The results suggest that quercetin was able to efficiently potentiate the effect of γδ T cells and modulate Wnt/β-catenin signalling pathway. (banglajol.info)
  • Co-Administration of Turmeric Potentiates Preventive Effect of Black S" by A H. Gilani, F Amin et al. (aku.edu)
  • However, the emotion potentiated effect was abolished in the volunteers receiving ondansetron. (ox.ac.uk)
  • Promethazine likely potentiates the opioid effect. (cdc.gov)
  • Potentiating effect. (cdc.gov)
Responses1
  • Removal of tetracycline from the growth media resulted in time-dependent increases in CD44 expression in MCF7F cells, promoting increased cell invasion and migration responses in addition to potentiating the adhesion of MCF7F cells to BMECs. (biomedcentral.com)
Mechanism1
  • Overall, our study sheds light on the molecular mechanism by which LCTx-F2 potentiates coagulation factors , providing valuable insights that may assist in designing drugs targeting procoagulation factors. (bvsalud.org)
Findings1
  • Collectively, these findings suggest down-regulation of Mcl-1 by either CDK inhibitors or genetic approaches dramatically potentiate ABT-737 lethality through cooperative interactions at two distinct levels: unleashing of Bak from both Bcl-xL and Mcl-1 and simultaneous induction of Bak activation and Bax translocation. (aacrjournals.org)
Receptor1
  • In contrast with neonatal cardiomyocytes, angiotensin II potentiated DNA synthesis and induced cell cycle regulated gene expression in AT-1 cardiomyocytes, and this activity was mediated by the angiotensin II type-1 receptor. (elsevierpure.com)
Cancer4
  • Does Biopsy Potentiate Cancer? (newmediaexplorer.org)
  • Galectin-7 Expression Potentiates HER-2-Positive Phenotype in Breast Cancer PloS One , vol. 11 , nº 11. (inrs.ca)
  • These data suggest that gal-7 could potentiate the phenotype of HER-2 positive primary breast cancer. (inrs.ca)
  • Through testing an enzymatically resistant, cancer-targeting, modulator based on carbohydrate imaging that restores physiological pH, this could potentiate other cancer therapies and resolve the issue around the pH of TME. (wesparkhealth.com)
Cell2
  • It appears that these oscillations of membrane potential may be potentiated by cholinergic mechanisms which regulate cell membrane ion channels, thus serving to change excitability in a rhythmic manner. (karger.com)
  • MnCl2 in drinking water did not cause hearing impairment or hair cell pathologies by itself and it did not potentiate noise-induced hearing loss or hair cell pathologies. (cdc.gov)
Journal1
  • Fukuda, K & Izumo, S 1998, ' Angiotensin II potentiates DNA synthesis in AT-1 transformed cardiomyocytes ', Journal of Molecular and Cellular Cardiology , vol. 30, no. 10, pp. 2069-2080. (elsevierpure.com)
Noise1
  • Occupational exposure to manganese and noise potentiate hearing loss. (cdc.gov)
Release1
  • Energy transfer implies the release of potential energies across , shall we say, a potentiated space . (lawofone.info)
Acute5
  • J Strength Cond Res 25(12): 3319-3325, 2011-This study examined the acute potentiating effects of back squats on athlete performance with a specific focus on movement specificity and the individual timing of potentiation. (unboundmedicine.com)
  • TY - JOUR T1 - The acute potentiating effects of back squats on athlete performance. (unboundmedicine.com)
  • Hypercalcemia due to all trans retinoic acid in the treatment of acute promyelocytic leukemia potentiated by voriconazole. (qxmd.com)
  • Thinking outside the cell: how cell-free hemoglobin can potentiate acute lung injury. (nih.gov)
  • Bastarache JA, Roberts LJ 2nd, Ware LB. Thinking outside the cell: how cell-free hemoglobin can potentiate acute lung injury. (nih.gov)
Temozolomide1
  • PAM-OBG: A monoamine oxidase B specific prodrug that inhibits MGMT and generates DNA interstrand crosslinks, potentiating temozolomide and chemoradiation. (oncotarget.com)
Anxiolytic1
  • We have shown in a series of studies that anxiolytic compounds that potentiate GABA facilitate extinction of positively reinforced fixed-ratio operant behaviour in C57B1/6 male mice. (reading.ac.uk)
Morphine1
  • Conclusions Ketamine, although not itself an epidural analgesic agent, potentiates the analgesic effect of morphine, especially when administered as a pretreatment. (bmj.com)
Inflammation2
  • Systemic inflammation potentiates cochlear uptake of aminoglycosides and increases the risk of hearing loss in both preclinical models and human studies. (elsevierpure.com)
  • Steyger, Peter S. / Inflammation potentiates cochlear uptake of ototoxins and drug-induced hearing loss . (elsevierpure.com)
Opioid3
  • Simply, to potentiate an opioid drug means to max out the drug's potential to intensify the euphoric effects of the opioid. (evokewellnessfl.com)
  • Still, in recent years during the opioid crisis, other methods to potentiate opioids have surfaced. (evokewellnessfl.com)
  • Evoke Wellness at Miramar has been providing specialized treatment programs for opioid addicts who potentiate their opiate drugs. (evokewellnessfl.com)
Cytotoxicity1
  • Reconstitution of galectin-3 alters glutathione content and potentiates TRAIL-induced cytotoxicity by dephosphorylation of Akt. (nih.gov)
Effects4
  • The study results also suggest that the potentiating effects of squats may exhibit some degree of movement specificity, being greater for those exercises with similar movement patterns. (unboundmedicine.com)
  • Importantly, diindolylmethane treatment potentiated the effects of cisplatin in SKOV-3 cells by targeting STAT3. (biomedcentral.com)
  • These results indicate that cocaine increases synaptic Zn release and turnover/metabolism in the striatum, and that synaptically released Zn potentiates the effects of cocaine on striatal DA neurotransmission and behavior and is required for cocaine-primed reinstatement. (nih.gov)
  • The term to describe how to increase a drug's effects is to potentiate the substance. (evokewellnessfl.com)
Tumor1
  • Lung cancer stem-like cells sustain tumor growth and potentiate metastasis. (medscape.com)
Antioxidant2
  • A nano-Liposomal formulation potentiates antioxidant, anti-inflammatory, and fibrinolytic activities of Allolobophora caliginosa coelomic fluid: formulation and characterization. (bvsalud.org)
  • The current study disclosed that liposomal formulation potentiates the biological activities of ACCF, especially antioxidant , anti-inflammatory, and thrombolytic activities. (bvsalud.org)
Immune response2
  • This study demonstrates that the Ascaris-Plasmodium interaction is harmful to the host and suggests that this coinfection may potentiate Ascaris -associated pathology by dampening the Ascaris -specific immune response, resulting in the early death of affected animals. (biomedcentral.com)
  • We show here for the first time that the T cell immune response is potentiated by TCR/CD28-mediated recruitment of PDE4 to lipid rafts, which counteracts the local, TCR-induced production of cAMP. (ox.ac.uk)
Activity1
  • Results: The novel compound, NMZ, was shown to retain the GABAA potentiating actions of CMZ in vitro and sedative activity in vivo. (nih.gov)
Methods1
  • Additionally, other methods to potentiate opioids are to ingest sleep aids and sedatives, soaking opiate pills in water to break down time-release sealants, particularly with time-released oxycontin, as well as consuming grapefruit juice. (evokewellnessfl.com)
Treatment2
  • Enzyme potentiated desensitization (EPD), is a treatment for allergies developed in the 1960s by Dr. Leonard M. McEwen in the United Kingdom. (wikipedia.org)
  • Treatment of cells expressing wild- type PS1 with a cell surface receptor agonist to stimulate the phosphoinositide second messenger pathway evoked Ca 2+ -activated Cl - currents that were significantly potentiated relative to controls. (elsevierpure.com)
Drugs3
Common1
  • The most common ways addicts potentiate opiates include consuming other opioids and prescription medications, consuming alcohol, and benzodiazepines such as Xanax, using over the counter medications such as Benadryl or other antihistamines, or using herbal remedies such as Valerian or St. John's wort. (evokewellnessfl.com)
Study1
  • The current study was designed to investigate whether LEV can potentiate the antidyskinetic action of amantadine. (aspetjournals.org)
Activation1
  • They show that exposure to VIP alone leads to modest activation of ILCs, but strongly potentiates ILCs to concomitant or subsequent activation by the inducer cytokines (IL-33 and IL-25 for ILC2s or IL-23 and IL-1b for ILC3s) to activate innate immunity. (pasteur.fr)
Suggest1
  • These data suggest that gal-7 could potentiate the phenotype of HER-2 positive primary breast cancer. (inrs.ca)
Health1
  • NatureBee Potentiated Bee Pollen is a 100% natural vegetable food that supports every single aspect of your health and wellbeing. (naturebee.com)
Determine1
  • To determine which elements of the signal transduction pathway are responsible for the potentiation, we used photolysis of caged inositol 1,4,5- trisphosphate (IP 3 ) and fluorescent Ca 2+ imaging to demonstrate that PS1 potentiates IP 3 -mediated release of Ca 2+ from internal stores. (elsevierpure.com)