Potent pi3k inhibitor. Medical search. Frequent questions

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Anatomy26

K562 Cells Cell Line, Tumor Cells, Cultured Cell Line Tumor Cells, Cultured Cell Membrane Epithelial Cells Cell Line, Transformed Fibroblasts Endothelium, Vascular Endothelial Cells Muscle, Smooth, Vascular Neurons 3T3 Cells Myocytes, Smooth Muscle HL-60 Cells Myocardium HeLa Cells Myocytes, Cardiac Hepatocytes Neutrophils CHO Cells Cell Nucleus Aorta Lung Macrophages

Organisms10

Rats, Sprague-Dawley Mice, Nude Mice, Inbred C57BL Rabbits Mice, Knockout Cattle Rats, Wistar Cricetinae Mice, Inbred BALB C Escherichia coli

Diseases11

Breast Neoplasms Neoplasms Disease Models, Animal Cell Transformation, Neoplastic Neoplasm Invasiveness Glioblastoma Myocardial Reperfusion Injury Prostatic Neoplasms Lung Neoplasms Adenocarcinoma Vitamin K Deficiency Bleeding

Chemicals and Drugs143

Phosphatidylinositol 3-Kinases Chromones Morpholines Proto-Oncogene Proteins c-akt Androstadienes Enzyme Inhibitors Phosphatidylinositol 3-Kinase Indazoles Cathepsin K Gonanes Class I Phosphatidylinositol 3-Kinases PTEN Phosphohydrolase Protein Kinase Inhibitors Protein-Serine-Threonine Kinases TOR Serine-Threonine Kinases Proto-Oncogene Proteins Class Ia Phosphatidylinositol 3-Kinase Oncogene Protein v-akt Butadienes Class Ib Phosphatidylinositol 3-Kinase H(+)-K(+)-Exchanging ATPase Sulfonamides Ribosomal Protein S6 Kinases, 70-kDa Phosphatidylinositol Phosphates Furans Mitogen-Activated Protein Kinases Aminopyridines Extracellular Signal-Regulated MAP Kinases Nitriles Flavonoids Quinolines Vitamin K bcl-Associated Death Protein Sirolimus Phosphoric Monoester Hydrolases Imidazoles Mitogen-Activated Protein Kinase Kinases Class II Phosphatidylinositol 3-Kinases Antineoplastic Agents Ribosomal Protein S6 Kinases RNA, Small Interfering Vitamin K 1 Diphenylamine Triazines Isoenzymes Mitogen-Activated Protein Kinase 3 ras Proteins Pyrimidines Glycogen Synthase Kinase 3 Insulin Insulin Antagonists Mitogen-Activated Protein Kinase 1 MAP Kinase Kinase Kinases Phosphoproteins Caspase 3 Protein Kinase C Receptor, erbB-3 3-Phosphoinositide-Dependent Protein Kinases Calcium Pyridines NF-kappa B src-Family Kinases p38 Mitogen-Activated Protein Kinases Insulin-Like Growth Factor I Receptor, Epidermal Growth Factor Cathepsins Protein-Tyrosine Kinases Insulin Receptor Substrate Proteins Protein Kinases Polyenes MAP Kinase Kinase 1 RNA, Messenger Intracellular Signaling Peptides and Proteins Potassium Channels rac1 GTP-Binding Protein Tyrphostins Indoles Phosphatidylinositols Recombinant Proteins 1-Phosphatidylinositol 4-Kinase Glucose Culture Media, Serum-Free Forkhead Transcription Factors Platelet-Derived Growth Factor Epidermal Growth Factor Apoptosis Regulatory Proteins Phosphotransferases (Alcohol Group Acceptor)Sodium-Potassium-Exchanging ATPase Proto-Oncogene Proteins c-bcl-2 Protein Subunits Tyrosine Tumor Suppressor Proteins Myeloid Cell Leukemia Sequence 1 Protein Carrier Proteins Caspases Receptor, erbB-2 Actins Reactive Oxygen Species Quinazolines Protein Isoforms Cyclic AMP-Dependent Protein Kinases Adaptor Proteins, Signal Transducing Calcium-Calmodulin-Dependent Protein Kinases Caspase 9 Adenosine Triphosphate Cyclin-Dependent Kinase Inhibitor p27 Cyclin D1 Leptin Phosphatidylinositol 4,5-Diphosphate Membrane Proteins Vascular Endothelial Growth Factor A Cyclic AMP Nitric Oxide Synthase Type III Hypoxia-Inducible Factor 1, alpha Subunit STAT3 Transcription Factor Sodium Proteins Tumor Necrosis Factor-alpha JNK Mitogen-Activated Protein Kinases Nitric Oxide Transcription Factors DNA Glutathione S-Transferase pi Hydrogen Peroxide Neuroprotective Agents Interleukin-8 Trans-Activators DNA-Binding Proteins Potassium Channel Blockers Ouabain alpha 1-Antitrypsin Lipopolysaccharides Interleukin-6 HIV Protease Inhibitors Membrane Glycoproteins Estradiol Lysine Recombinant Fusion Proteins Glutathione Transferase Adenosine Diphosphate Rubidium Collagen Symporters

Analytical, Diagnostic and Therapeutic Techniques and Equipment22

Blotting, Western Xenograft Model Antitumor Assays Transfection Molecular Targeted Therapy Immunoblotting Models, Biological Reverse Transcriptase Polymerase Chain Reaction Tumor Burden Gene Knockdown Techniques Flow Cytometry Culture Media, Serum-Free Immunohistochemistry Disease Models, Animal Immunoprecipitation Microscopy, Fluorescence Isoelectric Focusing Isoelectric Point Precipitin Tests Electrophoresis, Polyacrylamide Gel Models, Molecular Mutagenesis, Site-Directed Amino Acid Substitution

Phenomena and Processes43

Signal Transduction Phosphorylation Apoptosis Enzyme Activation MAP Kinase Signaling System Cell Proliferation Cell Survival Dose-Response Relationship, Drug Drug Synergism Drug Resistance, Neoplasm Transfection Up-Regulation Down-Regulation Time Factors Mutation Cell Movement Cell Division RNA Interference Cell Cycle Gene Expression Regulation Protein Transport Cell Adhesion Gene Expression Regulation, Neoplastic Chemotaxis Gene Expression Protein Structure, Tertiary Protein Binding Kinetics Amino Acid Sequence Cell Differentiation Gene Expression Regulation, Enzymologic Isoelectric Point Hydrogen-Ion Concentration Biological Transport Cell Death Transcription, Genetic Base Sequence Molecular Weight Oxidative Stress Structure-Activity Relationship Promoter Regions, Genetic Amino Acid Substitution Biological Transport, Active

Disciplines and Occupations1

Immunohistochemistry

Information Science3

Molecular Sequence Data Amino Acid Sequence Base Sequence

Anatomy Organisms Diseases Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Disciplines and Occupations Information Science

Phosphatidylinositol 3-Kinases Chromones Morpholines Proto-Oncogene Proteins c-akt Androstadienes Enzyme Inhibitors Phosphatidylinositol 3-Kinase Signal Transduction K562 Cells Indazoles Cathepsin K Gonanes Class I Phosphatidylinositol 3-Kinases Phosphorylation PTEN Phosphohydrolase Protein Kinase Inhibitors Cell Line, Tumor Protein-Serine-Threonine Kinases TOR Serine-Threonine Kinases Proto-Oncogene Proteins Apoptosis Class Ia Phosphatidylinositol 3-Kinase Cells, Cultured Oncogene Protein v-akt Butadienes Enzyme Activation Class Ib Phosphatidylinositol 3-Kinase H(+)-K(+)-Exchanging ATPase MAP Kinase Signaling System Cell Proliferation Cell Survival Sulfonamides Ribosomal Protein S6 Kinases, 70-kDa Phosphatidylinositol Phosphates Cell Line Blotting, Western Furans Mitogen-Activated Protein Kinases Aminopyridines Extracellular Signal-Regulated MAP Kinases Nitriles Flavonoids Quinolines Vitamin K Dose-Response Relationship, Drug bcl-Associated Death Protein Sirolimus Drug Synergism Phosphoric Monoester Hydrolases Imidazoles Mitogen-Activated Protein Kinase Kinases Rats, Sprague-Dawley Class II Phosphatidylinositol 3-Kinases Antineoplastic Agents Ribosomal Protein S6 Kinases RNA, Small Interfering Vitamin K 1 Diphenylamine Triazines Isoenzymes Mitogen-Activated Protein Kinase 3 ras Proteins Xenograft Model Antitumor Assays Pyrimidines Tumor Cells, Cultured Glycogen Synthase Kinase 3 Drug Resistance, Neoplasm Transfection Insulin Up-Regulation Down-Regulation Molecular Targeted Therapy Time Factors Mutation Insulin Antagonists Mice, Nude Mitogen-Activated Protein Kinase 1 Cell Movement Mice, Inbred C57BL Cell Division MAP Kinase Kinase Kinases Phosphoproteins Caspase 3 Protein Kinase C Receptor, erbB-3 3-Phosphoinositide-Dependent Protein Kinases RNA Interference Calcium Pyridines NF-kappa B Immunoblotting src-Family Kinases Cell Membrane p38 Mitogen-Activated Protein Kinases Cell Cycle Insulin-Like Growth Factor I Gene Expression Regulation Receptor, Epidermal Growth Factor Cathepsins Protein Transport

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