Chloride and hydrogenions are secreted separately from the cytoplasm of parietal cells and mixed in the canaliculi. (wikipedia.org)
This creates a negative potential of between −40 and −70 mV across the parietal cell membrane that causes potassiumions and a small number of sodiumions to diffuse from the cytoplasm into the parietal cell canaliculi. (wikipedia.org)
Sodium and potassiumions are closely coupled with membrane ATPase which undergoes phosphorylation and dephosphorylation, thereby providing energy for transport of these ions against concentration gradients. (childrensmercy.org)
NHEs mediate the secondary active extrusion of hydrogen (H+) ions out of cells in exchange for extracellular sodium (Na+). (thermofisher.com)
Halberg's team found that Nha1 can lead to a buildup of charged potassium particles, or ions , outside the cells. (snexplores.org)
An acid is a substance that can donate hydrogenions (H + ). A base is a substance that can accept H + ions. (medscape.com)
ATPase5
The basic components included in the model are the reactions at complexes I, III, and IV of the electron transport system, ATP synthesis at F1F0 ATPase, substrate transporters including adenine nucleotide translocase and the phosphate\u2013hydrogen co-transporter, and cation fluxes across the inner membrane including fluxes through the K+/H+ antiporter and passive H+ and K+ permeation. (physiomeproject.org)
Sodium-Potassium-Exchanging ATPase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (childrensmercy.org)
This graph shows the total number of publications written about "Sodium-Potassium-Exchanging ATPase" by people in this website by year, and whether "Sodium-Potassium-Exchanging ATPase" was a major or minor topic of these publications. (childrensmercy.org)
Below are the most recent publications written about "Sodium-Potassium-Exchanging ATPase" by people in Profiles. (childrensmercy.org)
A qRT-PCR assay indicated that GB enhanced NaCl-induced expression of genes encoding the K transporter, Na/H antiporter, and H-ATPase. (oregonstate.edu)
Efflux1
Genetic engineering of the biosynthesis of glycinebetaine leads to alleviate salt-induced potassium efflux and enhances salt tolerance in tomato plants. (oregonstate.edu)
Mediate1
This latter effect may mediate increased Na/H antiporter activity in a number of chronic conditions. (jci.org)
Chloride1
In addition to its functions as an electrolyte, chloride combines with hydrogen in the stomach to make hydrochloric acid, a powerful digestive enzyme that is responsible for the break down of proteins, absorption of other metallic minerals, and activation of intrinsic factor, which in turn absorbs vitamin B12. (t3db.ca)
PROTONS1
They are ANTIPORTERS that exchange vesicular PROTONS for cytoplasmic NEUROTRANSMITTER and play an essential role in regulating neurotransmission. (uams.edu)
Transporters1
These results suggest that the enhanced salt tolerance conferred by codA in transgenic tomato plants might be due to the regulation of ion channel and transporters by GB, which would allow high potassium levels and low sodium levels to be maintained in transgenic plants under salt stress condition. (oregonstate.edu)
Diuretic2
Potassium depletion with both vomiting and diuretic effects also contribute to the maintenance process. (abdominalkey.com)
Amiloride is classified as a potassium-sparing diuretic. (worldsbest.rehab)
Transport2
Which of the following defines the type of transport by the sodium-potassium pump? (pearson.com)
Active transport through an antiporter. (pearson.com)
Activity5
Amiloride is the treatment of choice for Liddle phenotype, which is characterized by high blood pressure, low blood potassium, and metabolic alkalosis in conjunction with a low plasma renin activity and a low aldosterone. (worldsbest.rehab)
To examine the role of protein kinase C as a chronic regulator of proximal tubule Na/H antiporter activity, the effect of phorbol 12-myristate 13-acetate (PMA) on the Na/H antiporter was studied in cultured proximal tubule cells. (jci.org)
Short-term activation of protein kinase C by 5 min exposure to PMA caused an acute increase in Na/H antiporter activity that was not prevented by cycloheximide or actinomycin D and did not persist 24 h later. (jci.org)
Long-term activation of protein kinase C by 2 h exposure to PMA caused a dose-dependent increase in Na/H antiporter activity 24 h later. (jci.org)
In conclusion, short-term activation of protein kinase C leads to a transient increase in Na/H antiporter activity that is independent of transcription and translation, whereas long-term activation of protein kinase C causes a persistent increase in antiporter activity that is dependent on transcription and translation and is associated with increased mRNANa/H abundance. (jci.org)
High3
The risk of high blood potassium is greater in those with kidney problems, diabetes, and those who are older. (worldsbest.rehab)
For example, people that are taking Digitalis (i.e. digoxin) are at higher risk for changes in heart rhythm if their potassium levels get too high. (worldsbest.rehab)
Long-term activation of protein kinase c causes chronic Na/H antiporter stimulation in cultured proximal tubule cells. (jci.org)
Channel2
Amiloride blocks the epithelial sodium channel (ENaC) in the late distal tubule, connecting tubule, and collecting duct of the nephron, which both reduces absorption of sodium ion from the lumen of the nephron and reduces excretion of potassium ion into the lumen. (worldsbest.rehab)
Because Liddle phenotype usually involves an upregulation of ENaC channels, leading to retention of sodium and water and to hypokalemia, amiloride is useful as an ENaC channel inhibitor due to its promotion of sodium excretion and its potassium-sparing effects, restoring potassium to normal levels. (worldsbest.rehab)
Cell1
Na+/H+ exchangers-1-6 (Na+/H+ antiporters, NHE-1-6) are integral membrane proteins that are expressed in most mammalian tissues where they regulate intracellular pH and cell volume. (thermofisher.com)
Cells1
Proximal tubule cells exposed to PMA for 2 h demonstrated a two- to threefold increase in Na/H antiporter mRNA (mRNANa/H) abundance 4 h later. (jci.org)
The potassium-sparing effects of amiloride offset the low blood potassium (hypokalemia) that is often induced by thiazides or loop diuretics, which is of particular importance in people for whom maintaining a normal level of potassium is critically important. (worldsbest.rehab)
Proton2
Predicted to enable sodium:proton antiporter activity. (mcw.edu)
This gene encodes a sodium and potassium/ proton antiporter that is a member of the solute carrier family 9 protein family. (nih.gov)
Evidence of alpha 1-adrenergic----protein kinase C----Na+/H+ antiporter-dependent increase in pinealocyte intracellular pH. (nih.gov)
Na+/H+ exchangers-1-6 (Na+/H+ antiporters, NHE-1-6) are integral membrane proteins that are expressed in most mammalian tissues where they regulate intracellular pH and cell volume. (thermofisher.com)
20021
Further layers face charged to prevent how the trenches of top shop Distant Lands and Diverse Cultures: The French Experience in Asia, 1600 1700 2002 have moved in the antiporter and how controversial and literal timelines be it, in website to hydroxylase or Sulphur grim in the sophoronol-7-methyl. (edvgruber.eu)
Sodium and potassium levels2
Most of a red blood cell's metabolic energy is used to maintain the imbalance between exterior and interior sodium and potassium levels required by the cell. (edu.vn)
Cowpea plants did not present significant differences in sodium and potassium levels when grown under non-saline conditions, but sodium content was strongly increased under salt stress conditions. (scielo.br)
Protein3
Further analysis indicated that norepinephrine is probably acting via an alpha 1-adrenergic----[Ca2+]i----Ca2+/phospholipid- dependent protein kinase (protein kinase C) mechanism to activate the Na+/H+ antiporter, thereby causing cytoplasmic alkalization. (nih.gov)
This the basic method that protein antiporters and symporters use to bring crucial nutrients into cells. (biologydictionary.net)
Animals, including humans, eat plants to acquire carbohydrates (as well as other animals to obtain protein and fat), ultimately removing the hydrogen and combining it with oxygen to regenerate water. (musculoskeletalkey.com)
Under non-saline and salt stress conditions, plants co-inoculated with Bradyrhizobium and Actinomadura or co-inoculated with Bradyrhizobium and Paenibacillus graminis showed lower hydrogen peroxide content in their nodules, whereas lipid peroxidation was increased by 31% in plants that were subjected to salt stress. (scielo.br)
observed that the accumulation of hydrogen peroxide (H 2 O 2 ) and severe lipid peroxidation caused by acidic soil (low pH) is due to the decreased activities of antioxidant enzymes such as superoxide dismutase (SOD) and catalase (CAT) in rice and cucumber. (frontiersin.org)
Homeostasis1
La acción de tales antiportadores influye en el pH intracelular y en la homeostasis de los iones potasio. (bvsalud.org)
Concentrations3
In contrast, although inhibitory effects of these compounds on cAMP accumulation were detectable, they occurred at 10-100-fold higher concentrations, and the relative potency of these inhibitors did not indicate they were acting via the antiporter. (nih.gov)
The interior of living cells is electrically negative with respect to the extracellular fluid in which they are bathed, and at the same time, cells have higher concentrations of potassium (K + ) and lower concentrations of sodium (Na + ) than does the extracellular fluid. (edu.vn)
Five analogs of the antiporter inhibitor amiloride reduced norepinephrine stimulation of cGMP accumulation with the same relative potency as they act on the antiporter. (nih.gov)
Oxygen3
In addition to these reprogramming events, we have demonstrated that BPA exposure generates reactive oxygen species and promotes cellular survival when co-exposed with the oxidizing agent potassium bromate (KBrO3). (nih.gov)
The hydrogen is then attached to carbon to create glucose and starch, while the oxygen is released into the atmosphere. (musculoskeletalkey.com)
Organic compounds are chemical compounds comprised of carbons bonded to elements, such as hydrogen, oxygen, and nitrogen. (studysmarter.co.uk)
Nutrient1
Potassium (K(+)) is a major plant nutrient required for growth and development. (nih.gov)
ndert and 2018HessenBayernLandtagswahlen neurons formed in this region shipping also take that power potassium to catalase-peroxidase plaintiffs which marries reported defined in early dieses well much as liver results of industries stay a specific biodegradation in leasing the maintenance of analytics with cytotoxic plants. (edvgruber.eu)
Elements1
The situation is more complex, however, for other elements such as potassium. (edu.vn)
Blood1
Problems that interfere with the neurons' sodium/potassium pump can cause death very quickly because the heart muscle itself relies on these electrochemical impulses to pump blood to keep us alive. (biologydictionary.net)