Loading...
  • synapse
  • In contrast, the probability of SPN innervation by NPY-neurogliaform interneurons was extremely high, the synapse very reliable (no failures were observed), and the resulting postsynaptic response was a slow, GABA A receptor-mediated IPSC that has not been previously described in striatum but that has been elicited from NPY-GABAergic neurogliaform interneurons in cortex and hippocampus. (jneurosci.org)
  • interneuron
  • The novel NPY interneuron type (NPY-neurogliaform) differed from previously described NPY-PLTS interneurons by exhibiting a significantly lower input resistance and hyperpolarized membrane potential, regular, nonaccommodating spiking in response to depolarizing current injections, and an absence of plateau depolarizations or low-threshold spikes. (jneurosci.org)
  • concentrations
  • For example , the fluidizing actions of barbiturates on membrane phospholipids are rather small until supratherapeutic concentrations are reached. (acnp.org)
  • activity
  • Action potential generation, propagation, and the initiating events causing transmitter release from the synaptic terminus are determined by the activity of a variety of ion channels. (fz-juelich.de)
  • The first one, referred to as the "covariance" protocol, obeys a generalized Hebbian framework, by imposing, for different stimuli, supervised positive and negative changes in covariance between postsynaptic and presynaptic activity rates. (frontiersin.org)
  • hippocampus
  • These data indicate that CDKL5 plays an important role in controlling postsynaptic localization of the GluN2B-SAP102 complex in the hippocampus. (nih.gov)
  • negative
  • outward diffusion of K+ ions makes the interior of the membrane more negative and the exterior more positive, which significantly alters the RMP. (getbodysmart.com)