- The purpose of this study was to determine whether a diuretic effect may be detectable in patients treated with eplerenone, a mineralocorticoid receptor antagonist, as compared with placebo during the first month of EPHESUS (Eplerenone Post-Acute Myocardial Infarction Heart Failure Efficacy and Survival study) (n = 6,080) and whether this was associated with eplerenone's beneficial effects on cardiovascular outcomes. (nih.gov)
- An acute myo-cardial infarction is a life threatening condition and often causes impairment of quality of life for the pati-ents and for the family. (romanianjournalcardiology.ro)
- Improving survival of stable patients with symptomatic heart failure with reduced ejection fraction (HFrEF) after an acute myocardial infarction. (nih.gov)
- Eplerenone tablets are indicated to improve survival of stable patients with symptomatic heart failure with reduced ejection fraction (≤40%) (HFrEF) after an acute myocardial infarction (MI). (nih.gov)
- Crenshaw BS et al (2000) Risk factors, angiographic patterns, and outcomes in patients with ventricular septal defect complicating acute myocardial infarction. (springermedicine.com)
- 8 In the UK, around 110 000 men and 65 000 women have an acute myocardial infarction every year, equivalent to one every three minutes. (bmj.com)
- To investigate the clinical effects of mindfulness-based stress reduction (MBSR) intervention combined with early cardiac rehabilitation (CR) on patients with acute myocardial infarction (AMI) assisted with an intra-aortic balloon pump (IABP). (frontiersin.org)
- Identification of potential molecular targets of acute myocardial infarction is crucial to our comprehensive understanding of the disease mechanism. (hindawi.com)
- However, studies of gene coexpression analysis via jointing multiple microarray data of acute myocardial infarction still remain restricted. (hindawi.com)
- Microarray data of acute myocardial infarction (GSE48060, GSE66360, GSE97320, and GSE19339) were downloaded from Gene Expression Omnibus database. (hindawi.com)
- A total of 1027 differentially expressed genes and 33 specific modules were screened out between acute myocardial infarction patients and control samples. (hindawi.com)
- FCN1 , CD14 , S100A9 , ALDH2 , hsa-let-7d , hsa-let-7b , hsa-miR-124-3, and hsa-miR-9-1 were identified as potential candidate regulators in acute myocardial infarction. (hindawi.com)
- Acute myocardial infarction (AMI) is characterized by definite evidence of myocardial necrosis in a clinical background of acute myocardial ischemia [ 1 ]. (hindawi.com)
- OBJECTIVE To identify factors associated with the uptake of cardiac rehabilitation following acute myocardial infarction. (bmj.com)
- PATIENTS Cohorts of patients admitted with acute myocardial infarction in 1992 and 1996. (bmj.com)
- Following acute myocardial infarction, a comprehensive cardiac rehabilitation programme can reduce the risk of fatal acute myocardial infarction, sudden death, and death from all causes. (bmj.com)
- 1 , 2 For those individuals with high levels of anxiety or depression after acute myocardial infarction, there is some evidence to suggest a more rapid psychological recovery 3-6 and quicker return to a normal quality of life, 7 although this is disputed. (bmj.com)
- KCNJ11 polymorphisms and sudden cardiac death in patients with acute myocardial infarction. (cdc.gov)
- Therefore, we examined effects of chronic anabolic T administration on left ventricular (LV) remodeling after myocardial infarction (MI). (ox.ac.uk)
- 13. Suzuki G, Weil BR, Young, Rebeccah, Fallavollita JA, Canty J. Nonocclusive Multivessel Intracoronary Infusion of Allogeneic Cardiosphere-derived Cells Early After Reperfusion Prevents Remote Zone Myocyte Loss and Improves Global Left Ventricular Function in Swine with Myocardial Infarction . (buffalo.edu)
- Although mortality from coronary heart disease has fallen over recent decades, annually it still claims an estimated 1.8 million lives in Europe, 7 and 785 000 new and 470 000 recurrent myocardial infarctions occur in the US. (bmj.com)
- Eplerenone survival benefits in heart failure patients post-myocardial infarction are independent from its diuretic and potassium-sparing effects. (nih.gov)
- The mechanism of the survival benefit of eplerenone in patients with heart failure post-myocardial infarction remains uncertain. (nih.gov)
- AIM: To examine the contribution of treatment resistant depression (TRD) to mortality in depressed post-myocardial infarction (MI) patients independent of biological and social predictors. (nih.gov)
- remote ischemic conditioning reduced infarct size in ST-elevation myocardial infarction (STEMI) patients when used in the ambulance or emergency department as an adjunct therapy to primary percutaneous coronary intervention (PCI), or when used with thrombolytic drugs. (wikipedia.org)
- These programmes are designed to limit the physiological and psychological effects of cardiac illness, reduce the risk for sudden death or re-infarction, control cardiac symptoms, stabilise or reverse the atherosclerotic process, and enhance the psychosocial and vocational status of selected patients. (bmj.com)
- As myocardial infarction is a major cause of mortality and morbidity in these patients, treatments that increase cell survival in response to ischaemia and reperfusion are needed. (researchgate.net)
- Among hypertensive patients, the mortality rate was higher only among those admitted with ST-elevation myocardial infarction. (who.int)
- this association is important as these patients have a worse prognosis following myocardial infarction. (bmj.com)
- Whereas CR originated as an exercise program primarily for middle-aged male patients with coronary heart disease (CHD), 1 usually after a myocardial infarction (MI) and/or coronary artery bypass surgery (CABG), the range of eligible diagnoses and applications for CR has broadened over time. (acc.org)
- So DY, Ha AC, Turek MA, Maloney JP, Higginson LA, Davies RF, Ryan SC, Le May MR. Comparison of mortality patterns in patients with ST-elevation myocardial infarction arriving by emergency medical services versus self-transport (from the prospective Ottawa Hospital STEMI Registry). (ottawaheart.ca)
- Cardiac tissue engineering, which combines cells and supportive scaffolds, is an emerging treatment for restoring cardiac function after myocardial infarction (MI), although, the optimal construct remains a challenge. (nature.com)
- Cinq-Mars A et al (2016) Risk factors of mortality after surgical correction of ventricular septal defect following myocardial infarction: Retrospective analysis and review of the literature. (springermedicine.com)
- Ischemic stroke is sudden neurologic deficits that result from focal cerebral ischemia associated with permanent brain infarction (eg, positive results on diffusion-weighted MRI). (msdmanuals.com)
- Genetic susceptibility for ischemic infarction and arteriolosclerosis based on neuropathologic evaluations. (cdc.gov)
- A myocardial infarction (MI), caused by an arterial blockage preventing blood from flowing to a part of the heart, restricts tissue oxygenation and results cell death and myocardial tissue damage. (ecu.edu)
- Lowering blood pressure reduces the risk of fatal and nonfatal cardiovascular events, primarily strokes and myocardial infarctions. (nih.gov)
- Cite this: Heart Failure Prevention Post-Myocardial Infarction: 5 Things to Know - Medscape - May 28, 2020. (medscape.com)
- Heart failure (HF) complicating myocardial infarction (MI) is common and may be present at admission or develop during the hospitalization. (nih.gov)
- Impact The targeted condition is heart failure arising from myocardial infarction or other insults causing focal heart muscle loss. (ca.gov)
- Myocardial infarction (MI) is a common condition that can lead to cardiac fibrosis and heart failure 1,2,3,4,5,6 . (tamhsc.edu)
- Furthermore, An injectable conductive hydrogel loaded with plasmid DNA and adipose-derived stem cells improved heart function and increased vessel density in rats with myocardial infarction 10 . (tamhsc.edu)
- Finally, an auxetic conductive cardiac patch for the treatment of myocardial infarction that is cytocompatible with cardiomyocytes, conforms to native heart movements, and in vivo experiments show negligible fibrotic response after two weeks, making it a versatile and robust platform for cardiac biomaterial design and a promising treatment option 11 . (tamhsc.edu)
- This is because the condition typically occurs after heart surgery, a myocardial infarction ( heart attack ), or an injury. (healthline.com)
- Cardiac tissue engineering, which combines the use of cells and biomaterials, has been proposed as an alternative therapy for myocardial infarction (MI) 1 , with the goals of repairing the damaged myocardium, recovering heart function, and preventing ventricular remodeling in end-stage heart failure. (nature.com)
- It's also called post-pericardiotomy syndrome, post-myocardial infarction syndrome, or post-cardiac injury syndrome. (healthline.com)
- Arnaoutakis GJ, Zhao Y, George TJ, Sciortino CM, McCarthy PM, Conte JV (2012) Surgical repair of ventricular septal defect after myocardial infarction: outcomes from the Society of Thoracic Surgeons National Database. (springermedicine.com)
- Singh V et al (2017) Ventricular septal defect complicating ST-elevation myocardial infarctions: a call for action. (springermedicine.com)
- Observer extra: Post-Myocardial Infarction 3 UFH is not recommended for use with a non-fibrin spepared with UFH. (abcdocz.com)
- Publication: Effective treatment of depression improves post-myocardial infarction survival. (nih.gov)
- Banankhah SK, Friedmann E, Thomas S. Effective treatment of depression improves post-myocardial infarction survival. (nih.gov)
- Cardiac rehabilitation is essential for ful-ly recovery of post myocardial infarction patient and for prevention of recurrence of the cardiac event. (romanianjournalcardiology.ro)
- Effect of testosterone on post-myocardial infarction remodeling and function. (ox.ac.uk)
- Molecular Mechanisms of Desensitization Underlying the Differential Effects of Formyl Peptide Receptor 2 Agonists on Cardiac Structure-Function Post Myocardial Infarction. (iric.ca)
- Thompson S, Redgrave R, Kirby J, Arthur H, Ali S. Modulation of wound healing post-myocardial infarction . (ncl.ac.uk)
- Influence of depression on utilization of cardiac rehabilitation postmyocardial infarction: A study of 158 991 Medicare beneficiaries. (ahrq.gov)
- The purpose of this study was to examine the association between depression diagnosis and participation in cardiac rehabilitation (CR) in a large sample of Medicare beneficiaries with recent myocardial infarction (MI). (ahrq.gov)
- The research goal of this project is to study the anti-inflammatory effect of docosahexaenoic acid (DHA) on TNF-1 signaling following myocardial infarction (MI). (nih.gov)
- 10. Melatonin attenuates postmyocardial infarction injury via increasing Tom70 expression. (nih.gov)