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  • atherosclerotic
  • Recent studies have investigated whether osteocalcin is associated with subclinical and clinical atherosclerotic coronary artery disease (CAD), but these studies have yielded inconsistent results. (biomedcentral.com)
  • ucOC
  • To understand the mechanism of the increase in the ucOC in the elderly and to assess its potential consequences on bone fragility, we have measured ucOC in the sera of 195 elderly institutionalized women 70-101 yr of age. (nih.gov)
  • In 45 women (23%) serum ucOC was above the upper limit of the normal range for young women. (nih.gov)
  • osteoblast
  • 2008). „Two of four alternatively spliced isoforms of RUNX2 control osteocalcin gene expression in human osteoblast cells. (wikipedia.org)
  • 2008). „General transcription factor IIA-gamma increases osteoblast-specific osteocalcin gene expression via activating transcription factor 4 and runt-related transcription factor 2. (wikipedia.org)
  • cohort study
  • This prospective Australian cohort study of nearly 25,000 women found that although the risk of breast cancer for recent users of HT was elevated by approximately 50%, any potential modifying effect of the association by factors such as alcohol intake and body mass index was likely to be modest. (lww.com)
  • hormones
  • DHEA serves as a precursor to male and female sex hormones (androgens and estrogens ). (webmd.com)
  • Androstenedione is then changed into the major male and female hormones. (webmd.com)
  • Relationship
  • Bao Y-Q, Zhou M, Zhou J, Lu W, Gao Y-C, Pan X-P, Tang J-L, Lu H-J, Jia W-P (2011) Relationship between serum osteocalcin and glycaemic variability in Type 2 diabetes. (springer.com)
  • The purpose of this study was to determine the relationship of osteocalcin with insulin resistance, insulin-like growth factor-1 (IGF-1) and inflammatory markers in women with RA. (omicsonline.org)
  • The present study suggests that inflammatory factors may modify in distinct ways the relationship between osteocalcin and carbohydrate metabolism in patients with RA. (omicsonline.org)
  • proteins
  • All three bone Gla-proteins are synthesized by the osteoblasts (the bone forming cells) and their importance became clear about 25 years ago, when it was realized that the use of vitamin K-antagonists (coumarin derivatives) in pregnant women was associated with serious bone defects in the foetus. (drmyhill.co.uk)
  • risk
  • Giving vitamin K to women at risk for very preterm births might reduce the severity of intraventricular hemorrhage in preterm infants. (webmd.com)
  • After multiple adjustment, the odds ratios (ORs) were substantially higher risk for carotid plaques (OR 1.77 for 1 SD decrease in osteocalcin, 95% CI 1.23-2.76, p=0.005). (biomedcentral.com)
  • In keeping with these observations, it is plausible to consider serum osteocalcin as a promising candidate for risk assessment and a potential intervention target for diabetic macrovascular diseases. (biomedcentral.com)
  • Tekin GO, Kekilli E, Yagmur J et al (2008) Evaluation of cardiovascular risk factors and bone mineral density in post menopausal women undergoing coronary angiography. (springer.com)