• Toxicity of adjuvant endocrine therapy in postmenopausal breast cancer patients: A systematic review and meta-analysis. (ons.org)
  • Influence of patient and treatment factors on adherence to adjuvant endocrine therapy in breast cancer. (ons.org)
  • American Society of Clinical Oncology clinical practice guideline: Update on adjuvant endocrine therapy for women with hormone receptor-positive breast cancer. (ons.org)
  • Quality of life of postmenopausal women in the ATAC ("Arimidex," tamoxifen, alone or in combination) trial after completion of 5 years' adjuvant treatment for early breast cancer. (ons.org)
  • We investigated the association between adjuvant endocrine therapy for breast cancer and risk of developing dementia in a real-world, population-based study. (ices.on.ca)
  • Methods - We used health administrative data collected from post-menopausal women (aged ≥66 years) who were diagnosed with breast cancer and started on adjuvant endocrine therapy from 2005 to 2012 with follow-up until 2017. (ices.on.ca)
  • To evaluate Arimidex 6 month therapy as an adjuvant treatment in postmenopausal patients with advanced breast cancer in whom a partial or complete response or stabilized disease were obtained with first line chemotherapy, by tumoral response assessment. (astrazenecaclinicaltrials.com)
  • The effects of adjuvant chemotherapy on the breast cancer disease seem to be as good for pre and postmenopausal patients, at least for hormone receptor negative patients. (diva-portal.org)
  • The aim of this study was to follow HRQOL in postmenopausal women (55−80 years) with breast cancer receiving adjuvant treatment after surgery, until five years post-treatment, and compare with a general population. (diva-portal.org)
  • Conclusion: Postmenopausal women (55−80 years) seem to successfully manage the effects of adjuvant treatment on HRQOL. (diva-portal.org)
  • ARIMIDEX is indicated for adjuvant treatment of postmenopausal women with hormone receptor-positive early breast cancer . (rxlist.com)
  • For adjuvant treatment of early breast cancer in postmenopausal women, the optimal duration of therapy is unknown. (rxlist.com)
  • Adjuvant trastuzumab cardiotoxicity in patients over 60 years of age with early breast cancer: a. (aicocardioncologia.it)
  • Purpose: There are few reports from Asian countries about the long-term results of aromatase inhibitor adjuvant treatment for breast cancer. (ewha.ac.kr)
  • Methods: Self-reported quality of life (QoL) scores were serially assessed for 3 years during adjuvant letrozole treatment using the Korean version of the Functional Assessment of Cancer Therapy-Breast questionnaires (version 3). (ewha.ac.kr)
  • Adjuvant chemotherapy was administered to 684 (76.3%) subjects, and 410 (45.7%) and 396 (44.1%) patients had stage I and II breast cancer, respectively. (ewha.ac.kr)
  • ExperimentalDesign: We investigated ERh by immunohistochemistry in 353 stage II primary breast tumors from patients treated with 2 years adjuvant tamoxifen, and generated gene expres- sion profiles for a representative subset of 88 tumors. (lu.se)
  • Conclusion: Expression of ERh is an independent marker for favorable prognosis after adjuvant tamoxifen treatment in ERa-negative breast cancer patients and involves a gene expression program distinct from ERa. (lu.se)
  • These results may be highly clinically significant, because in the United States alone, f10,000 women are diagnosed annually with ERa-negative/ERh-positive breast carcinoma and may benefit from adjuvant tamoxifen. (lu.se)
  • Patients who received (neo) adjuvant therapy for breast cancer are eligible. (who.int)
  • Fadrozole hydrochloride (CGS 16949A) is a highly potent, nonsteroidal aromatase inhibitor that significantly lowers estrogen levels in postmenopausal women and can he effective therapy for patients with advanced hormone-dependent breast carcinoma. (psu.edu)
  • Estrogen hormone therapy, or use of estradiol as a supplement, raises health concerns related to estradiol concentration in blood such as elevated levels in postmenopausal women increasing the risk of breast cancer. (cdc.gov)
  • Zhang and colleagues analyzed 796 patients with postmenopausal breast cancer who had not received hormone therapy. (medicalnewstoday.com)
  • The mission of the CTRC-AACR San Antonio Breast Cancer Symposium is to produce a unique and comprehensive scientific meeting that encompasses the full spectrum of breast cancer research, facilitating the rapid translation of new knowledge into better care for breast cancer patients. (health.am)
  • Cancer treatment of the elderly patients is an increasingly important concern since the risk for developing breast cancer increases with age. (diva-portal.org)
  • Patients and Methods: In all, 68,019 postmenopausal women, including 3,401 with diabetes at study entry, were observed over a mean of 11.8 years with 3,273 invasive breast cancers diagnosed. (johnshopkins.edu)
  • For patients with advanced breast cancer, the medication should be continued until tumor progression. (rxlist.com)
  • Of the 161,807 participants in the dataset we excluded 7,906 because of a possible history of breast cancer and 825 patients who could not influence the analysis because they did not have follow-up. (e-epih.org)
  • A particularly strong correlation with poor clinical outcome was seen in postmenopausal patients (p greater than 0.0005), an association which persisted in multivariate survival analysis. (lu.se)
  • PATIENTS AND METHODS: Conditional logistic regression was used to analyze the data from a case-control study nested within the prospective European EPIC cohort, including 2250 invasive breast cancer and their matched control subjects. (ox.ac.uk)
  • The phase III MONALEESA-3 trial included first- (1L) and second-line (2L) patients and demonstrated a significant overall survival (OS) benefit for ribociclib + fulvestrant in patients with hormone receptor-positive, human epidermal growth factor receptor 2-negative (HR+/HER2-) advanced breast cancer (ABC) in the final protocol-specified and exploratory (longer follow-up) OS analyses. (bvsalud.org)
  • Postmenopausal patients with HR+/HER2- ABC were randomized 21 to 1L/2L fulvestrant + ribociclib or placebo. (bvsalud.org)
  • To investigate how socioeconomic position (SEP) influences the effectiveness of cancer-directed treatment in premenopausal breast cancer patients in terms of breast cancer recurrence and mortality. (biomedcentral.com)
  • To overcome cytochrome P450 2D6 (CYP2D6) mediated tamoxifen resistance in postmenopausal early breast cancer, CYP2D6 phenotype-adjusted tamoxifen dosing in patients with impaired CYP2D6 metabolism and/or the application of endoxifen, the most potent tamoxifen metabolite, are alternative treatment options. (springeropen.com)
  • In conclusion, we suggest that co-administration of endoxifen in tamoxifen treated early breast cancer women with impaired CYP2D6 metabolism is a promising alternative to reach plasma concentrations comparable to CYP2D6 EM patients. (springeropen.com)
  • Update: On 02/03/2023 the FDA approved Trodelvy for patients with locally advanced or metastatic breast cancer who have received hormonal therapy and at least two other types of treatment in the metastatic setting. (facingourrisk.org)
  • It's been linked with an increased risk of breast cancer in these patients. (medlineplus.gov)
  • The study further concluded that breast cancer patients with an unfavorable lifestyle, compared with patients with a favorable lifestyle, had almost a two times higher overall mortality risk. (lifespa.com)
  • Purpose: Endocrine therapies, such as tamoxifen, are commonly given to most patients with estrogen receptor (ERa) ^ positive breast carcinoma but are not indicated for persons with ERa-negative cancer. (lu.se)
  • We assessed the efficacy and safety of the aromatase inhibitor anastrozole for prevention of breast cancer in postmenopausal women who are at high risk of the disease. (nih.gov)
  • Conclusion - Aromatase inhibitor therapy was associated with a decreased incidence of dementia as compared to treatment with tamoxifen among post-menopausal women with early stage breast cancer. (ices.on.ca)
  • Arimidex ( anastrozole ) is a non-steroidal aromatase inhibitor used to treat breast cancer in postmenopausal women. (rxlist.com)
  • Prolia was later approved to treat men with osteoporosis, glucocorticoid induced osteoporosis, bone loss in men receiving androgen deprivation therapy for prostate cancer and in women receiving aromatase inhibitor therapy for breast cancer. (medlineplus.gov)
  • Zhang and colleagues also investigated whether these higher hormone levels were more closely linked to hormone receptor- (HR) positive breast cancers and if they predicted risk regardless of tumor aggressiveness. (medicalnewstoday.com)
  • Zhang noted that the study had low case numbers for several cancer subgroups, including HER2-positive, triple-negative and basal-like breast cancers. (medicalnewstoday.com)
  • Follow-up of about 11 years of participants in the Women's Health Initiative finds that among postmenopausal women, use of estrogen plus progestin is associated with an increased incidence of breast cancers that are more advanced, and with a higher risk of deaths attributable to breast cancer, according to a study in the October 20 issue of JAMA . (medicaldaily.com)
  • Because some cancers, especially breast cancers, require estrogen to grow and spread, drugs that block estrogen production are often used to treat the disease. (health.am)
  • The primary endpoint was histologically confirmed breast cancer (invasive cancers or non-invasive ductal carcinoma in situ). (nih.gov)
  • The predicted cumulative incidence of all breast cancers after 7 years was 5·6% in the placebo group and 2·8% in the anastrozole group. (nih.gov)
  • Previous research has found links between periodontal disease and oral, esophageal, head and neck, pancreatic, and lung cancers, so the researchers wanted to see if there was any relationship with breast cancer. (medicalxpress.com)
  • 2019 Prevalence of US female breast cancer relative to other common cancers. (medscape.com)
  • Breast cancers were confirmed by review of central medical records and pathology reports. (johnshopkins.edu)
  • Doctors estimate that about 5 to 10 percent of breast cancers are linked to gene mutations passed through generations of a family. (mayoclinic.org)
  • If you have a strong family history of breast cancer or other cancers, your doctor may recommend a blood test to help identify specific mutations in BRCA or other genes that are being passed through your family. (mayoclinic.org)
  • Lower lifetime occurrence of breast cancer and cancers of the reproductive system among former college athletes. (jamanetwork.com)
  • Around 10% of all breast cancers are hormone receptor-positive and HER2-positive. (medicalnewstoday.com)
  • Among women, breast cancer is one of the most common cancers. (msdmanuals.com)
  • In the United States, breast cancer is the second most common cancer in women (skin cancers are most common). (msdmanuals.com)
  • other cancers, from prevention and early detection al y higher in more developed coun- such as those of the breast, prostate, to treatment, is therefore of great im- tries and generally increase with thyroid, and colon and rectum, have portance in controlling and reducing increasing levels of national socio- been, at least historical y, associated cancer mortality. (who.int)
  • Breast cancer is the most commonly diagnosed cancer among US women, with an estimated 268,600 newly diagnosed women with invasive disease (48,100 cases of ductal carcinoma in situ [DCIS]) in 2019, accounting for approximately 15.2%-30% of all new cancer cases among women, depending on the data sources. (medscape.com)
  • Phthalate biomarker concentrations did not result in an increased risk of developing invasive breast cancer , according to results from a prospective subgroup analysis of women enrolled in the Women's Health Initiative (WHI). (cancertherapyadvisor.com)
  • Although the study authors didn't observe a large increase in invasive breast cancer risk as concentrations of phthalate biomarkers increased, they also "weren't able to completely rule out a smaller effect on breast cancer risk," said Katherine W. Reeves, PhD, MPH, of the University of Massachusetts Amherst, who is the study's corresponding author. (cancertherapyadvisor.com)
  • Conclusion: Metformin use in postmenopausal women with diabetes was associated with lower incidence of invasive breast cancer. (johnshopkins.edu)
  • Women with this kind of breast cancer face a higher risk of invasive breast cancer, but death from DCIS itself is rare. (medindia.net)
  • Breast cancer most often begins with cells in the milk-producing ducts (invasive ductal carcinoma). (mayoclinic.org)
  • Breast cancer may also begin in the glandular tissue called lobules (invasive lobular carcinoma) or in other cells or tissue within the breast. (mayoclinic.org)
  • In 2023, in men in the United States, it is estimated there will be 2800 new cases of invasive breast cancer and 530 deaths from it. (msdmanuals.com)
  • In 2005-2006, 57,164 participants provided some updated information, including use of NSAIDs and 1457 of these participants developed invasive breast cancer before January 2013. (medscape.com)
  • Multivariable Cox proportional hazards regression models provided hazard rate ratios (HRR) for the association between NSAID use and risk of invasive breast cancer as well as hormone receptor- and HER2-defined subtypes. (medscape.com)
  • In brief, it was a long-term national health study that focused on strategies for preventing heart disease, breast and colorectal cancer, and osteoporosis in postmenopausal women. (e-epih.org)
  • BACKGROUND: Prolia is a prescription medicine approved in June 2010 to treat postmenopausal women with osteoporosis at high risk for bone fracture. (medlineplus.gov)
  • When FDA first approved Prolia, we required the manufacturer, Amgen, to conduct a long-term safety study in women with postmenopausal osteoporosis and men with osteoporosis. (medlineplus.gov)
  • Tamoxifen blocks the effect of estrogen in breast tissue, whereas aromatase inhibitors prevent the production of estrogen. (health.am)
  • For example, although tamoxifen blocks estrogen production in breast tissue, it has the opposite effect in uterine tissue. (health.am)
  • The researchers examined data from seven large randomized clinical trials that compared tamoxifen with aromatase inhibitors in postmenopausal women with early-stage breast cancer. (health.am)
  • ARIMIDEX is indicated for the treatment of advanced breast cancer in postmenopausal women with disease progression following tamoxifen therapy. (rxlist.com)
  • Tamoxifen and anastrazole are both very effective to help prevent breast cancer, but it seems that women have better chances of staying well with anastrazole. (medindia.net)
  • After 10 years, 93.5 percent of women in the anastrazole group were living breast cancer-free, compared to 89.2 percent in the tamoxifen group. (medindia.net)
  • It is also well known that breast tissue density increases in about 25%-30% of women who begin hormone replacement therapy and that, conversely, breast density decreases in some women who are placed on tamoxifen or raloxifene. (medscape.com)
  • The efficacy of the selective estrogen receptor modulator tamoxifen, the backbone of the treatment of estrogen receptor positive early breast cancer in postmenopausal women, is based on its bio-activation to 4-hydroxylated metabolites by hepatic cytochrome P450 (CYP) enzymes (Brauch et al. (springeropen.com)
  • Based on clinical studies there is an increasing body of evidence that the in vivo metabolism of tamoxifen in postmenopausal early breast cancer depends on CYP2D6, thereby altering tamoxifen response (Brauch et al. (springeropen.com)
  • Tamoxifen attaches to the hormone receptors in the breast cancer cells, stopping them from accessing the hormones they need to multiply. (medicalnewstoday.com)
  • Between Feb 2, 2003, and Jan 31, 2012, we recruited postmenopausal women aged 40-70 years from 18 countries into an international, double-blind, randomised placebo-controlled trial. (nih.gov)
  • Methods: Relative weight at age 12 years (above, below, or average weight compared with peers) and family history were ascertained using a mailed questionnaire in 1986, in the Iowa Women's Health Study, a prospective cohort study of postmenopausal women. (elsevierpure.com)
  • Reproductive risk factors in a prospective study of breast cancer: the Nurses' Health Study. (medscape.com)
  • In an earlier prospective study among pre- and postmenopausal women not using exogenous hormones, we obs. (biomedcentral.com)
  • Active and passive smoking in breast cancer: prospective results from the Nurses' Health Study. (jamanetwork.com)
  • This study assessed the prospective risk of breast cancer (overall and by subtype) according to use of aspirin and other non-steroidal anti-inflammatory medications (NSAIDs) in a cohort of female public school professionals in California. (medscape.com)
  • Freudenheim and colleagues monitored 73,737 postmenopausal women enrolled in the Women's Health Initiative Observational Study, none of whom had previous breast cancer. (medicalxpress.com)
  • For the study, Neuhouser and her colleagues collected data on more than 67,000 postmenopausal women who took part in a study called the Women's Health Initiative from 1993 to 1998. (feelgoodnatural.com)
  • Influence of estrogen plus progestin on breast cancer and mammography in healthy postmenopausal women: the Women's Health Initiative Randomized Trial. (bmj.com)
  • Subjects were incident breast cancer cases ( N = 497) and a subcohort ( N = 2,830) of Women's Health Initiative (WHI) participants with available fasting insulin and glucose levels. (nyu.edu)
  • Therefore, we assessed associations among diabetes, metformin use, and breast cancer in postmenopausal women participating in Women's Health Initiative clinical trials. (johnshopkins.edu)
  • Among eligible postmenopausal women not using postmenopausal hormones (PMH) at blood collection, 796 cases were diagnosed through June, 2010. (medicalnewstoday.com)
  • Most other intercourse steroid hormones, together with androgens and progesterone, are also going to donate to the partnership ranging from obesity and you may cancer of the breast. (sch.gr)
  • Endogenous hormones and breast cancer risk. (medscape.com)
  • ARIMIDEX is indicated for the first-line treatment of postmenopausal women with hormone receptor-positive or hormone receptor unknown locally advanced or metastatic breast cancer. (rxlist.com)
  • Palbociclib works by blocking a key protein that fuels the growth of hormone receptor-positive breast tumors. (medindia.net)
  • There was no heterogeneity in the prolactin-breast cancer association by hormone receptor status of the tumor. (ox.ac.uk)
  • Zhang SMHankinson SEHunter DJGiovannucci ELColditz GAWillett WC Folate intake and risk of breast cancer characterized by hormone receptor status. (jamanetwork.com)
  • One or both of these receptors means the breast cancer is hormone-receptor positive. (medicalnewstoday.com)
  • Few studies have addressed whether risk reduction pertains to specific breast cancer subtypes defined jointly by hormone receptor (estrogen and progesterone receptor) and human epidermal growth factor receptor 2 (HER2) expression. (medscape.com)
  • High consumption of total meat compared with none was associated with premenopausal breast cancer, HR=1.20 (95% CI: 0.86-1.68), and high non-processed meat intake compared with none, HR=1.20 (95% CI: 0.86-1.68). (nature.com)
  • Out of the more than 45,000 women who completed the high school food frequency questionnaire, 870 were diagnosed with premenopausal breast cancer, and 490 were diagnosed with postmenopausal breast cancer. (lifespa.com)
  • Certain evidence suggests an interaction between cooking methods and diet in breast cancer causation. (nature.com)
  • Treating triple-positive breast cancer may include using a combination of treatment methods, which may vary for each individual case. (medicalnewstoday.com)
  • Obesity is known to increase estrogens in the postmenopausal women because estrogen is made by fat tissue," Neuhouser said. (feelgoodnatural.com)
  • Three independent case control studies have shown an increased risk od endometrial cancer in postmenopausal women exposed to exogenous estrogens for prolonged periods. (drugs.com)
  • Estrogens play an important role for the development and Authors' Affiliations: Departments of 1Oncology and 2Theoretical Physics, Lund progression of breast carcinoma. (lu.se)
  • These graphs illustrate 2019 US female breast cancer statistics at glance from the National Cancer Institute (NCI)'s Surveillance, Epidemiology, and End Results Program (SEER). (medscape.com)
  • Breast cancer statistics, 2019. (medscape.com)
  • The risk for breast cancer among the most obese women in the study was up to 58 percent higher than for normal-weight women. (feelgoodnatural.com)
  • The researchers found that very obese women were at risk for estrogen- and progesterone-driven breast cancer, but not for other types. (feelgoodnatural.com)
  • The researchers found that among all women, the risk of breast cancer was 14 percent higher in women who had periodontal disease. (medicalxpress.com)
  • Women who gained more than 5 percent of their body weight over the years of the study also had an increased risk for breast cancer, according to the researchers. (feelgoodnatural.com)
  • In addition, hormone replacement therapy had no effect on the risk for breast cancer, regardless of weight, the researchers said. (feelgoodnatural.com)
  • The researchers therefore set out to examine the association between drinking patterns and the risk for sarcopenia among postmenopausal women. (medscape.com)
  • Researchers said that comparable benefits were seen in both pre- and postmenopausal women, but more long term research is needed to determine whether or not the drug helps women live longer. (medindia.net)
  • Researchers have identified hormonal, lifestyle and environmental factors that may increase your risk of breast cancer. (mayoclinic.org)
  • After initial hormonal therapy stops working in metastatic breast cancer, the next step is typically chemotherapy, which can be effective, but the side effects are often very difficult for women," said lead study author Nicholas C. Turner, a consultant medical oncologist at The Royal Marsden and a team leader at The Institute of Cancer Research, London, United Kingdom. (medindia.net)
  • The study TROPiCS-2 showed that the drug Trodelvy (sacituzumab govitecan) improved progression-free survival when compared to chemotherapy in people with advanced metastatic ER/PR-positive, HER2-negative breast cancer who have few other treatment options. (facingourrisk.org)
  • 4.Patient has a histologically and/or cytologically confirmed diagnosis of estrogen-receptor positive and/or progesterone receptor positive breast cancer by local laboratory. (who.int)
  • Blood hormone tests predicted a woman's risk for developing postmenopausal breast cancer for up to 20 years, according to data from the Nurses' Health Study presented at the 11th Annual AACR International Conference on Frontiers in Cancer Prevention Research. (medicalnewstoday.com)
  • 12 Genesis Breast Cancer Prevention Centre, Manchester, UK. (nih.gov)
  • Obesity is a risk factor for breast cancer that is modifiable, making a healthy weight very important for prevention," said lead researcher Marian Neuhouser, a professor of epidemiology at the Fred Hutchinson Cancer Research Center in Seattle. (feelgoodnatural.com)
  • Historically, women have had slightly higher exposures to phthalates than men, but the increased use of phthalates can be found in "everything from personal care products to industrial adhesives and building materials," according to Breast Cancer Prevention Partners, so "everyone is equally at risk for exposure. (cancertherapyadvisor.com)
  • These results can inform future studies evaluating metformin use in breast cancer management and prevention. (johnshopkins.edu)
  • Prevention and early detection of sarcopenia among postmenopausal women could therefore help to prevent aging-related diseases. (medscape.com)
  • A new study in the Cancer Epidemiology, Biomarkers & Prevention journal finds a strong link between poor adolescent and early adult diets and breast cancer. (lifespa.com)
  • Background: Although plasma estrogen and androgen levels are significantly positively associated with risk of postmenopausal breast cancer, it is unknown how long a single blood hormone measure can predict subsequent breast cancer risk as most prior studies have included less than 10 years of follow-up. (medicalnewstoday.com)
  • THURSDAY, June 11, 2015 (HealthDay News) - A study of more than 67,000 women suggests that those who are obese and postmenopausal may face significantly higher odds for breast cancer compared with slimmer women. (feelgoodnatural.com)
  • C-myc amplification, and especially a high gene copy number (greater than 5 copies), was significantly related to early recurrence and death in breast cancer, a relationship seen in both the lymph-node-negative and node-positive subcategories. (lu.se)
  • The most well-known are breast cancer gene 1 (BRCA1) and breast cancer gene 2 (BRCA2), both of which significantly increase the risk of both breast and ovarian cancer. (mayoclinic.org)
  • Recent declines in hormone therapy utilization and breast cancer incidence: clinical and population-based evidence. (medscape.com)
  • In a multicenter, randomized, double-blind, placebo-controlled clinical trial, the effects of Prometrium Capsules on the endometrium was studied in a total of 875 postmenopausal women. (medicinenet.com)
  • Public lectures with municipali- female breast cancer each year clinical breast examina- ties and women NGOs are being organized by worldwide. (who.int)
  • Anastrozole effectively reduces incidence of breast cancer in high-risk postmenopausal women. (nih.gov)
  • The international incidence of female breast cancer varies markedly, being highest in the United States and Northern Europe, intermediate in Southern and Eastern Europe and South America, and lowest in Asia. (medscape.com)
  • From 1983 to 1987, the age-adjusted incidence rate of breast cancer varied by factor of about 5 between countries (see image below). (medscape.com)
  • 1982 Average annual breast cancer incidence per 100,000 women by age in San Francisco, United States, Japan, and China. (medscape.com)
  • Breast cancer incidence rates increase sharply with age, becoming substantial before age 50 years. (medscape.com)
  • [ 5 , 6 ] The rate of increase in breast cancer incidence continues throughout life but slows substantially after menopause, to approximately 2%-3% per year. (medscape.com)
  • A detailed analysis of SEER data from 1975-2004 included 440,653 cases of breast cancer and showed a consistent finding of higher age-specific incidence of breast cancer among black women compared to white women younger than 40 years. (medscape.com)
  • According to a study from the American Cancer Society (ACS), in 2012, the breast cancer rates converged among black and white women even though white women have historically had higher incidence rates. (medscape.com)
  • The incidence rate ratio (95% confidence interval) for breast cancer was 1.09 (1.02-1.17) for total meat, 1.15 (1.01-1.31) for red meat and 1.23 (1.04-1.45) for processed meat per 25 g daily increment in intake. (ku.dk)
  • Purpose: Emerging evidence suggests that metformin may reduce breast cancer incidence, but reports are mixed and few provide information on tumor characteristics. (johnshopkins.edu)
  • Cox proportional hazards regression, adjusted for breast cancer risk factors, compared breast cancer incidence in women with diabetes who were metformin users or nonusers with breast cancer incidence in women without diabetes. (johnshopkins.edu)
  • Results: Compared with that in women without diabetes, breast cancer incidence in women with diabetes differed by diabetes medication type (P = .04). (johnshopkins.edu)
  • Breast cancer in Singapore: trends in incidence 1968-1992. (medscape.com)
  • DeSantis CE, Fedewa SA, Goding Sauer A, Kramer JL, Smith RA, Jemal A. Breast cancer statistics, 2015: Convergence of incidence rates between black and white women. (medscape.com)
  • Breast cancer incidence in Asian migrants to the United States and their descendants. (medscape.com)
  • Recent trends in breast cancer incidence in Sweden. (medscape.com)
  • Quinn M, Allen E. Changes in incidence of and mortality from breast cancer in England and Wales since introduction of screening. (medscape.com)
  • Matheson I, Tretli S. Changes in breast cancer incidence among Norwegian women under 50. (medscape.com)
  • Aromatase inhibitors effectively prevent breast cancer recurrence and development of new contralateral tumours in postmenopausal women. (nih.gov)
  • abstract = "Adiposity is an established risk factor for postmenopausal breast cancer. (nyu.edu)
  • abstract = "Background: Early adolescent weight may affect the risk of postmenopausal breast cancer, and this association may be modified by a family history of breast or ovarian cancer in a first-degree relative, and/or estrogen (ER) and progesterone (PR) receptor status of the disease. (elsevierpure.com)
  • Inclusion criteria: 1.Women with advanced (locoregionally recurrent or metastatic) breast cancer not amenable to curative therapy. (who.int)
  • Elevated hormone levels were also associated with aggressive breast cancer, which the study defined as recurrent or fatal cancer. (medicalnewstoday.com)
  • This study will compare the effects of different amounts of aerobic exercise on heart and lung (cardiorespiratory) fitness in post-menopausal women who completed treatment for early-stage breast cancer. (mskcc.org)
  • While the study found an association between obesity and an increased risk of breast cancer, it did not prove a cause-and-effect link. (feelgoodnatural.com)
  • Women who lost weight during the study reduced their risk for breast cancer, Neuhouser said. (feelgoodnatural.com)
  • The aim of this study was to investigate whether polymorphisms in N-acetyl transferase 1 and 2 modify the association between meat consumption and risk of breast cancer. (ku.dk)
  • A nested case-control study was conducted among 24 697 postmenopausal women included in the 'Diet, Cancer and Health' cohort study (1993-2000). (ku.dk)
  • The present study assessed more than 800 potential risk factors to identify new predictors of breast cancer and compare the independence and relative importance of established risk factors. (e-epih.org)
  • Risk factors previously reported that were not independently associated with breast cancer in the present study included socioeconomic status, months of breast feeding, age at first birth, adiposity measures, adult weight gain, timing of initiation of hormone therapy, and several dietary, psychological, and exercise variables. (e-epih.org)
  • Relative risks (RR) and 95% confidence intervals (95% CI) were estimated using Cox proportional hazards regression, and were adjusted for breast cancer risk factors, including body mass index at age 18 years and body mass index at study baseline. (elsevierpure.com)
  • High-risk alcohol consumption is associated with a greater risk for muscle tissue loss in postmenopausal women, a new study shows. (medscape.com)
  • Of the 2373 postmenopausal women (mean age, 62.4 years) included in the study, 188 (8.2%) met the criteria for sarcopenia. (medscape.com)
  • A third study released at ASCO and published in the New England Journal of Medicine found that women who have a bit of extra tissue removed around the tumor during breast-conserving surgery, or partial mastectomy, face a reduced risk that cancer will be left behind. (medindia.net)
  • The study involved 235 women with breast cancer diagnoses ranging from stage 0 to 3, some of whom were randomly assigned to have extra tissue around the tumor removed -- known as cavity shave margins (CSM) -- and some who were not. (medindia.net)
  • Colditz GA, Rosner B. Cumulative risk of breast cancer to age 70 years according to risk factor status: data from the Nurses' Health Study. (medscape.com)
  • CONCLUSION: Our study indicates that higher circulating levels of prolactin among the postmenopausal HRT users at baseline may be associated with increased breast cancer risk. (ox.ac.uk)
  • We performed a survival analysis to assess the effect of meat consumption and meat type on the risk of breast cancer in the UK Women's Cohort Study. (nature.com)
  • The UK Women's Cohort Study (UKWCS), which was established in 1993 to investigate diet in relation to cancer and mortality from selected causes, is well placed to examine meat consumption and breast cancer risk, the subject of this paper. (nature.com)
  • Lee IMRexrode KMCook NRHennekens CHBurin JE Physical activity and breast cancer risk: the Women's Health Study (United States). (jamanetwork.com)
  • Sesso HDPaffenbarger RS JrLee IM Physical activity and breast cancer risk in the College Alumni Health Study (United States). (jamanetwork.com)
  • This observational study aimed to evaluate the long-term effects of letrozole in postmenopausal Korean women with operable breast cancer. (ewha.ac.kr)
  • A large study looked at the effects of adding the bone-protective drug denosumab (Prolia), to standard hormone therapy for the treatment of early-stage, postmenopausal, HR-positive breast cancer. (facingourrisk.org)
  • A diet high in sugar, refined carbohydrates, and red and processed meat makes it more likely that you may experience early onset breast cancer," said study senior author Karin Michels, chair of epidemiology at the UCLA Fielding School of Public Health in Los Angeles. (lifespa.com)
  • For adolescents and young adults, when mammary glands are rapidly developing, this study concludes a healthy lifestyle and diet may provide long-term breast health protection. (lifespa.com)
  • This is not the first study suggesting that a healthy diet may lower risk of breast cancer. (lifespa.com)
  • In a comprehensive article on breast cancer risk, one study evaluated suspected breast cancer lifestyle risk factors. (lifespa.com)
  • The study concluded that menopausal women who did not use hormone therapy and had an unfavorable lifestyle (compared with women who had a favorable lifestyle) had a twofold higher risk for postmenopausal breast cancer. (lifespa.com)
  • Cite this: Heavy Drinking Increases Postmenopausal Sarcopenia Risk - Medscape - Jun 08, 2017. (medscape.com)
  • Health outcomes for a cohort of postmenopausal women (n=21 523) with average age 62.2 years at baseline were assessed over 11 years from the Danish hospital, death records and cancer register. (bmj.com)
  • Analyses performed in 2011 and 2012 used the Cox proportional hazard regression to test the association between more than 800 baseline risk factors and incident breast cancer. (e-epih.org)
  • Black women have poorer 5-year survival rates from breast cancer at all ages of diagnosis compared to white women. (medscape.com)
  • Breast cancer survival rates have increased, and the number of deaths associated with this disease is steadily declining, largely due to factors such as earlier detection, a new personalized approach to treatment and a better understanding of the disease. (mayoclinic.org)
  • Updated overall survival from the MONALEESA-3 trial in postmenopausal women with HR+/HER2- advanced breast cancer receiving first-line ribociclib plus fulvestrant. (bvsalud.org)
  • To diagnose triple-positive breast cancer, doctors will test a biopsy sample for hormone receptors and HER2 levels. (medicalnewstoday.com)
  • One possible explanation for the link between periodontal disease and breast cancer is that those bacteria enter the body's circulation and ultimately affect breast tissue. (medicalxpress.com)
  • Fat tissue also secretes inflammatory factors and is associated with insulin resistance - all of which may increase breast cancer risk. (feelgoodnatural.com)
  • Each breast contains 15 to 20 lobes of glandular tissue, arranged like the petals of a daisy. (mayoclinic.org)
  • 0(0) smoking, high alcohol consumption, ing in the breast tissue. (who.int)
  • These women were also more likely to have large tumors and cancer that spread beyond the breast and into the lymph nodes. (feelgoodnatural.com)
  • Dr Kwon and colleagues therefore stress the need for further studies to incorporate the AUDIT or other similar measures to clarify this association between high-risk alcohol drinking and sarcopenia among postmenopausal women. (medscape.com)