• The base of tongue is the site for the posterior opening of the oral cavity, the entrance of the pharynx and esophagus, and the inferior aspect of the nasopharynx .The surgical management of malignant neoplasms of the tongue base remains difficult despite recent advances in diagnostic techniques. (medscape.com)
  • The anatomic location of the hypoglossal nerve within the base of the tongue puts it at risk from invasion or compression from malignant neoplasms at the primary site or metastatic disease in the neck. (medscape.com)
  • The disease process and treatment often affect adjacent structures, such as the posterior floor of the mouth, larynx, and esophagus. (medscape.com)
  • Hypopharyngeal cancers are often named for their location, including pyriform sinus, lateral pharyngeal wall, posterior pharyngeal wall, or postcricoid pharynx (see images below). (medscape.com)
  • As in other head and neck cancer sites, more than 95% of hypopharyngeal malignancies arise from the epithelium of the mucosa and, therefore, are squamous cell cancers. (medscape.com)
  • Of patients with hypopharyngeal cancers, 70% have stage III disease at presentation. (medscape.com)
  • In the United States and Canada, 65-85% of hypopharyngeal carcinomas involve the pyriform sinuses, 10-20% involve the posterior pharyngeal wall, and 5-15% involve the postcricoid area. (medscape.com)
  • Hypopharyngeal cancer is a term used for tumors of a subsite of the upper aerodigestive tract, and like most other subsite designations, the distinction is anatomic rather than pathophysiologic within the group of head and neck malignancies . (medscape.com)
  • An anaplastic, highly malignant, and usually bronchogenic carcinoma composed of small ovoid cells with scanty neoplasm. (lookformedical.com)
  • Cricopharyngeal muscle impression: Extrinsic impression on posterior esophagus by contracted muscle. (radiologyassistant.nl)
  • The incidence of laryngeal cancer is 4-5 times that of hypopharyngeal cancer. (medscape.com)
  • In a retrospective cohort study, Kuo et al reported a decline in the incidence of hypopharyngeal cancer in the United States by an average of -2.0% annually between 1973 and 2010. (medscape.com)
  • Patients diagnosed with hypopharyngeal cancer are typically men aged 55-70 years with a history of tobacco use and/or alcohol ingestion. (medscape.com)
  • The aforementioned study by Kuo and colleagues found that the 5-year overall survival rate for hypopharyngeal cancer rose significantly from 1988-1990 and from 1991-1995 but that no significant changes in survival rate could be demonstrated for other years. (medscape.com)
  • It is a histological type of neoplasm but is often wrongly used as a synonym for "cancer. (lookformedical.com)
  • A malignant skin neoplasm that seldom metastasizes but has potentialities for local invasion and destruction. (lookformedical.com)
  • Transfer of a neoplasm from its primary site to lymph nodes or to distant parts of the body by way of the lymphatic system. (lookformedical.com)
  • It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. (lookformedical.com)
  • 9. A case of peritoneal metastasis during treatment for hypopharyngeal squamous cell carcinoma. (nih.gov)
  • 18. [Clinical analysis of posterior hypopharyngeal wall squamous cell carcinoma: a report of 36 cases]. (nih.gov)
  • In the United States and Canada, 65-85% of hypopharyngeal carcinomas involve the pyriform sinuses, 10-20% involve the posterior pharyngeal wall, and 5-15% involve the postcricoid area. (medscape.com)
  • 12. [Clinical study of the sentinel lymph node of patients with laryngeal and hypopharyngeal carcinomas]. (nih.gov)
  • 14. [Application of rigid curved laryngoscope in the examination of hypopharynx and the treatment of early hypopharyngeal cancer]. (nih.gov)
  • 1. [Application of transverse cervical artery flap in laryngeal function preservation surgery of hypopharyngeal carcinoma]. (nih.gov)
  • 10. Surgical treatment of T2-3 posterior hypopharyngeal carcinoma with preservation of laryngeal function. (nih.gov)
  • 15. [One-stage repair of pharyngeal defect using tongue flaps after resection of advanced stage hypopharyngeal neoplasm and laryngeal neoplasm]. (nih.gov)
  • 16. [Laryngeal function preservation and voice reconstruction in surgical treatment of hypopharyngeal and cervical esophageal carcinoma]. (nih.gov)
  • The incidence of laryngeal cancer is 4-5 times that of hypopharyngeal cancer. (medscape.com)
  • Objective Larynx preservation is the current standard for locally advanced (LA) laryngeal/hypopharyngeal tumors, but not all patients respond as expected. (bvsalud.org)
  • Methods We retrospectively evaluated 175 patients diagnosed from July 2008 to December 2015 with LA laryngeal/hypopharyngeal carcinoma and treated with a laryngeal preservation scheme comprising induction chemotherapy followed by concomitant chemotherapy and radiotherapy. (bvsalud.org)
  • Hypopharyngeal cancers are often named for their location, including pyriform sinus, lateral pharyngeal wall, posterior pharyngeal wall, or postcricoid pharynx (see images below). (medscape.com)
  • It includes the pyriform sinuses, the hypopharyngeal walls, and the postcricoid region (i.e., the area of the pharyngoesophageal junction). (medscape.com)
  • The hypopharyngeal lymph usually flows directly into the superior nodes of the deep cervical chain. (who.int)
  • 6. [Application of gastric pull up and complex laryngotracheal flap to reconstruct the circumferencial defect after resection of the hypopharyngeal and cervical esophageal cancers]. (nih.gov)
  • 8. [Laryngo-tracheal flap to reconstruct the defect after resection of the hypopharyngeal carcinoma with cervical esophagus involvement]. (nih.gov)
  • The melanoma was discovered during a 2-year followup after treatment for hypopharyngeal cancer and esophageal melanosis, leading to surgery. (amjcaserep.com)
  • Som [4] emphasized the importance of removing these nodes when attempting radical resection of pharyngo-oesophageal neoplasms and advocated dissection of the lymph nodes lying above the innominate vein in the superior mediastinum. (who.int)
  • The caseload in Malindi, Kenya, was quite exciting, with many cases that are rarely seen here in the U.S. These included extremely large goiters, benign tumors of odontogenic origin, salivary neoplasms, and benign skin lesions. (entnet.org)
  • It is bounded anteriorly by the posterior face of the cricoid cartilage. (medscape.com)
  • It includes the soft palate and uvula, the base of the tongue, the pharyngoepiglottic and glossoepiglottic folds, the palatine arch (which includes the tonsils and the tonsillar fossae and pillars), the valleculae, and the lateral and posterior oropharyngeal walls. (medscape.com)
  • Twenty-five patients with hypopharyngeal carcinoma underwent total laryngopharyngo-oesophagectomy with complete paratracheal clearance. (who.int)
  • The incidence of metastatic involvement of the PTNs in patients with hypopharyngeal carcinoma, as well as the clinicopathological factors associated with their metastases are not adequately documented. (who.int)
  • Twenty-five patients suffering from primary hypopharyngeal cancer were treated between 1990 and 1992. (who.int)
  • 3. [Treatment and prognosis of 264 patients with hypopharyngeal carcinoma]. (nih.gov)
  • Patients diagnosed with hypopharyngeal cancer are typically men aged 55-70 years with a history of tobacco use and/or alcohol ingestion. (medscape.com)
  • 11. Superficial temporal artery flap: a new option for posterior hypopharyngeal wall reconstruction. (nih.gov)
  • The incidence of positive paratracheal lymph nodes was 40% in hypopharyngeal tumours. (who.int)
  • The nasopharynx extends from the posterior choanae to the inferior surface of the soft palate. (medscape.com)
  • The present study aimed to evaluate the clinicopathological characteristics of primary hypopharyngeal carcinoma and neck secondaries, which are associated with PTN metastases. (who.int)
  • 7. [Clinical characteristics of 97 hypopharyngeal carcinoma cases]. (nih.gov)
  • Histological evidence of metastatic involvement of paratracheal lymph nodes in hypopharyngeal carcinoma and its clinicopathological implications were studied. (who.int)
  • The sphenoid sinus lies posterior to the nasal cavity and superior to the nasopharynx. (medscape.com)