Loading...
  • 2000
  • That barrier has on average, 2000 pores in it, each of which serve as a gatekeeper, either allowing a molecule through, or barring its entry. (phys.org)
  • proteins
  • The end result describes all of the interconnections and interactions of all of the proteins in each pore, which is itself part of a larger system. (phys.org)
  • actual pore
  • The second team took the opposite approach , using mass spectrometry, cryo-electron microscopy and finally computer modeling to create a realistic rendering of an actual pore. (phys.org)
  • researchers
  • In these two new efforts, both teams have managed to create maps of the different layers that make up the rings of the pores, offering other medical researchers a new way perhaps, to combat diseases that manage to make it through the NPC. (phys.org)
  • molecular
  • The nuclear pore complex (NPC) controls the transport of macromolecules between the nucleus and cytoplasm, but its molecular architecture has thus far remained poorly defined. (phys.org)
  • Molecular architecture of the inner ring scaffold of the human nuclear pore complex, Science (2016). (phys.org)
  • outer
  • Recently, it has been shown how the Y complex, a prominent NPC module, forms the outer rings of the nuclear pore. (phys.org)