• Currently, inactivated and live attenuated viruses are used to try to eliminate porcine reproductive and respiratory syndrome (PRRS). (wikipedia.org)
  • PRRS is an acronym (porcine reproductive and respiratory syndrome) for a viral disease characterized by two overlapping clinical presentations, reproductive impairment or failure in breeding animals, and respiratory disease in pigs of any age. (iastate.edu)
  • It was referred to as swine mystery disease (SMD) or swine infertility and respiratory syndrome (SIRS) before porcine reproductive and respiratory syndrome (PRRS) became the generally agreed-upon name. (iastate.edu)
  • An outbreak of porcine reproductive and respiratory syndrome (PRRS) has been reported in the northern province of Chiang Rai, with local authorities battling to curb the spread. (flutrackers.com)
  • PRRS is a viral disease characterized by two overlapping clinical presentations, reproductive impairment or failure in breeding animals, and respiratory disease in pigs of any age, around 50 pigs have died by the outbreak since May 10. (flutrackers.com)
  • Porcine reproductive and respiratory syndrome (PRRS) is a highly contagious, economically devastating disease. (idexx.co.uk)
  • The PRRS virus causes reproductive and respiratory disorders in the swine population worldwide and can result in severe economic losses. (merck-animal-health.com)
  • Our major research focus is the development of improved vaccines for porcine reproductive and respiratory syndrome (PRRS). (pirbright.ac.uk)
  • Although live-attenuated vaccines have been used for some time to control clinical symptoms of the porcine reproductive and respiratory syndrome (PRRS), the molecular bases for the attenuated phenotype remain unclear. (mcmaster.ca)
  • European workers introduced the term "porcine reproductive and respiratory syndrome" (PRRS), but because of its taxonomic classification the agent is also sometimes identified as "swine arterivirus. (extension.org)
  • PRRS exists in two distinct forms, reproductive and respiratory, and infected farms may experience one or both. (extension.org)
  • Porcine Respiratory and Reproductive Syndrome (PRRS) - also called swine infertility and respiratory syndrome (SIRS), porcine epidemic abortion and respiratory syndrome (PEARS), mystery swine disease (MSD) or blue ear disease - is among the world's most important diseases in pig production. (laboklin.com)
  • Porcine reproductive and respiratory syndrome (PRRS) is characterized by reproductive failure in sows and respiratory symptoms in piglets and growing pigs. (biomedcentral.com)
  • In the podcast Swine Extension Educator Sarah Schieck Boelke speaks with Mariana Kikuti, University of Minnesota researcher in the Department of Veterinary Medicine about her research on the length of time farms stay naïve of Porcine Reproductive and Respiratory Syndrome (PRRS) since last outbreak. (umn.edu)
  • Porcine reproductive and respiratory syndrome (PRRS) is now among the most important swine diseases that affect the Chinese swine industry. (visavet.es)
  • Porcine reproductive and respiratory syndrome (PRRS) is a highly contagious disease and the most economically important disease of the swine industry worldwide. (ijbs.com)
  • Abstract Porcine reproductive and respiratory syndrome (PRRS) is recognized as one of the most infectious viral diseases of swine. (chinaagrisci.com)
  • Effect of the host genotype at a Porcine Reproductive and Respiratory Syndrome (PRRS) resistance marker on evolution of the modified-live PRRS vaccine virus in pigs. (usda.gov)
  • Suvaxyn PRRS MLV is a veterinary vaccine used to protect pigs against porcine respiratory and reproductive syndrome (PRRS). (europa.eu)
  • According to 3news , the disease worrying farmers is Porcine Reproductive Respiratory Syndrome (PRRS), which is similar to HIV but can be transmitted through the air. (thepigsite.com)
  • Find out more information on porcine reproductive respiratory syndrome (PRRS) by clicking here . (thepigsite.com)
  • The role of porcine reproductive and respiratory syndrome (PRRS) virus structural and non-structural proteins in virus pathogenesis. (nih.gov)
  • Member viruses are a type of the porcine reproductive and respiratory syndrome viruses (PRRSV). (wikipedia.org)
  • PRRSV causes porcine reproductive and respiratory syndrome in swine. (wikipedia.org)
  • Syndrome, Vietnam PRRSV (Chinese genotype). (cdc.gov)
  • Porcine reproductive and respiratory syndrome virus (PRRSV) occurs in all age groups. (iastate.edu)
  • Current vaccines do not provide sufficient levels of protection against divergent porcine reproductive and respiratory syndrome virus (PRRSV) strains circulating in the field, mainly due to the substantial variation of the viral genome. (unl.edu)
  • Two common viral pathogens of swine, namely, porcine circovirus type 2 (PCV2) and porcine reproductive and respiratory syndrome virus (PRRSV), were investigated in regard to their effects on monolayer cultures of swine alveolar macrophages (AMs). (scienceopen.com)
  • Three-week-old cesarean-derived colostrum-deprived (CD/CD) pigs were inoculated with porcine circovirus type 2 (PCV2, n = 19), porcine reproductive and respiratory syndrome virus (PRRSV, n = 13), concurrent PCV2 and PRRSV (PCV2/PRRSV, n = 17), or a sham inoculum (n = 12) to compare the independent and combined effects of these agents. (scienceopen.com)
  • Microscopic lesions consistent with postweaning multisystemic wasting syndrome (PMWS) were present in both PCV2- and PCV2/PRRSV-inoculated pigs and included lymphoid depletion, necrotizing hepatitis, mild necrotizing bronchiolitis, and infiltrates of macrophages that occasionally contained basophilic intracytoplasmic inclusion bodies in lymphoid and other tissues. (scienceopen.com)
  • We are deploying cutting edge technologies to identify and characterise naturally occurring porcine monoclonal antibodies capable of broadly neutralising PRRSV strains. (pirbright.ac.uk)
  • The PRRSV-I dtec-RT-qPCR comprises a series of species-specific targeted reagents designed for Porcine reproductive and respiratory syndrome virus type I detection by using qPCR. (geneticpcr.com)
  • PRRSV causes a disease of pigs, called porcine reproductive and respiratory syndrome, also known as blue-ear pig disease, characterized by reproductive failure in breeding stock and respiratory tract illness in young pigs. (geneticpcr.com)
  • The type 2 highly pathogenic porcine reproductive and respiratory syndrome virus (HP-PRRSV) has spread throughout countries of southeast Asia, where it has caused severe economic losses. (biomedcentral.com)
  • Porcine reproductive and respiratory syndrome virus (PRRSV) has caused huge economic losses in the global swine industry. (researchsquare.com)
  • Porcine reproductive and respiratory syndrome virus (PRRSV) is an enveloped, single-stranded positive-sense RNA virus belonging to the family Arteriviridae of the order Nidovirales . (researchsquare.com)
  • PRRSV causes reproductive failure in sows and respiratory distress in pigs of all ages, resulting in significant economic losses for the swine industry worldwide (1, 2). (researchsquare.com)
  • PRRSV infection results in severe reproductive failure in gilts and respiratory disease in pigs of all ages and further complicates polymicrobial disease syndromes such as porcine circovirus-associated disease ( 3 ). (ijbs.com)
  • PRRSV challenge experiments in porcine alveolar macrophages (PAMs) isolated from the CD163-R561A pigs showed significantly lower susceptibility to PRRSV than that of CD163-R561 PAMs. (chinaagrisci.com)
  • Porcine reproductive and respiratory syndrome virus ( PRRSV ) causes significant economic losses to the pork industry worldwide. (bvsalud.org)
  • This study showed that artesunate (AS), one of the antimalarial drugs , potently suppressed PRRSV replication in Marc-145 cells and ex vivo primary porcine alveolar macrophages (PAMs) at micromolar concentrations. (bvsalud.org)
  • IMPORTANCE Porcine reproductive and respiratory syndrome virus ( PRRSV ) infections have continuously threatened the pork industry worldwide. (bvsalud.org)
  • We show that artesunate (AS), one of the antimalarial drugs , is a potent inhibitor against PRRSV replication in Marc-145 cells and ex vivo primary porcine alveolar macrophages (PAMs). (bvsalud.org)
  • Background: The between-and within-herd variability of porcine reproductive and respiratory syndrome virus (PRRSV) antibodies were investigated in a cross-sectional study of 103 British pig herds conducted 2003-2004. (birmingham.ac.uk)
  • Porcine reproductive and respiratory syndrome virus (PRRSV) induces one of most important devastating disease of swine worldwide, and the current methods poorly control it. (biomedcentral.com)
  • A non-naturally occurring porcine reproductive and respiratory syndrome virus (PRRSV) is provided herein, and methods of making and using the non-naturally occurring PRRSV also are provided. (unl.edu)
  • Field reports have suggested that transmission of porcine reproductive and respiratory syndrome virus (PRRSV) can occur by indirect means. (usda.gov)
  • Experiments were designed to determine if porcine reproductive and respiratory syndrome virus (PRRSV) or Bordetella bronchiseptica could be transmitted through indirect airborne contact. (usda.gov)
  • The first positive hit was an infection known as blue ear disease, or to give it its formal name - porcine reproductive and respiratory syndrome virus ( PRRSV ). (nationalgeographic.com)
  • Swine and poultry viruses, such as porcine reproductive and respiratory syndrome virus (PRRSV), porcine epidemic diarrhea virus (PEDV), and highly pathogenic avian influenza virus (HPAIV), are economically important pathogens that can spread via aerosols. (cdc.gov)
  • The respiratory syndrome is seen more often in young growing pigs but also occurs in naïve finishing pigs and breeding stock. (iastate.edu)
  • respiratory disease sickens pigs and makes them vulnerable to secondary infection. (idexx.co.uk)
  • A syndrome characterized by outbreaks of late term abortions, high numbers of stillbirths and mummified or weak newborn piglets, and respiratory disease in young unweaned and weaned pigs. (usda.gov)
  • Experimental reproduction of severe disease in CD/CD pigs concurrently infected with type 2 porcine circovirus and porcine reproductive and respiratory syndrome virus. (scienceopen.com)
  • In 1987, a new reproductive and respiratory disease of pigs was recognized in the United States. (extension.org)
  • It can cause severe reproductive failure in sows and respiratory distress in young growing pigs [ 2 ]. (biomedcentral.com)
  • The disease is characterized by reproductive disorders in sows and respiratory disorders in pigs. (biomedcentral.com)
  • Weaner and grower pigs show mainly varying degrees of respiratory distress, and up to 20% of pigs may die. (biomedcentral.com)
  • Thyroid dysfunction in feeder pigs following polymicrobial or porcine reproductive and respiratory syndrome virus-2 challenge. (usda.gov)
  • Phylogenetic analysis of porcine circovirus 3 circulating in Canadian pigs. (nih.gov)
  • Beside domestic pigs wild boars can also be affected by postweaning multisystemic wasting syndrome (PMWS). (vetline.de)
  • Development and characterization of new monoclonal antibodies against porcine Interleukin-17A and Interferon-gamma. (usda.gov)
  • Reproductive impairment or failure, more obvious in sows or gilts, also affects some boars. (iastate.edu)
  • The study comprised two reproductive phases (cycles) in two commercial farrow to finish farms: Farm A (capacity: 550 sows) and Farm B (capacity: 220 sows). (researchgate.net)
  • Development of a Nipah virus vaccine to eliminate porcine reservoirs and safeguard human health. (pirbright.ac.uk)
  • Members of the species are also known as porcine reproductive and respiratory syndrome virus 2. (wikipedia.org)
  • A Synthetic Porcine Reproductive and Respiratory Syndrome Virus Strain" by Hiep Vu, Fangrui Ma et al. (unl.edu)
  • It is caused by Porcine respiratory and reproductive syndrome virus. (usda.gov)
  • In addition, we are applying our expertise in porcine immunology and vaccinology to contribute to the development of vaccines to combat new and emerging zoonotic viruses, such as the Nipah virus and SARS-CoV-2. (pirbright.ac.uk)
  • Porcine reproductive and respiratory syndrome virus is a small, enveloped RNA virus, which contains a single-stranded, positive-sense, RNA genome with a size of 15 Kb. (geneticpcr.com)
  • Porcine reproductive and respiratory syndrome virus entry into the porcine macrophage. (chinaagrisci.com)
  • TANG Yomg, CHEN Huan-chun, HUANG Qin-feng, YAO Qing-xia, ZHAO Wu.The Construction of cDNA Library of Porcine Reproductive and Respiratory Syndrome Virus and the Sequence of Its Genome .VIROLOGICA SINICA, 2005, 20(2): 203-205. (virosin.org)
  • The Antimalaria Drug Artesunate Inhibits Porcine Reproductive and Respiratory Syndrome Virus Replication by Activating AMPK and Nrf2/HO-1 Signaling Pathways. (bvsalud.org)
  • Genome wide association study of thyroid hormone levels following challenge with porcine reproductive and respiratory syndrome virus. (usda.gov)
  • Detection of porcine enteric coronaviruses including porcine epidemic diarrhea virus (PEDV), transmissible gastroenteritis (TGE), and porcine deltacoronavirus (PDCoV), by real time PCR. (tamu.edu)
  • Recombination between Vaccine and Field Strains of Porcine Reproductive and Respiratory Syndrome Virus. (cdc.gov)
  • What this means is that the competition in the porcine reproductive and respiratory syndrome vaccine market in China is fierce with many players vying for a lucrative share of the market. (groupweb.com)
  • In all, the porcine reproductive and respiratory syndrome vaccine market constitutes about 26 manufacturers. (groupweb.com)
  • With this, companies in the porcine reproductive and respiratory syndrome vaccine market anticipate that the demand for pork and pork products will witness an increase over the next few years. (groupweb.com)
  • The regulatory environment and the procedural details associated with the procurement of porcine reproductive and respiratory syndrome vaccine in China by the government are also discussed at length. (groupweb.com)
  • In addition, diseases of the respiratory tract may occur. (laboklin.com)
  • Coinfections and their molecular consequences in the porcine respiratory tract. (nih.gov)
  • Detection of parvovirus in porcine species by PCR. (tamu.edu)
  • Here, we substituted exon 7 of porcine CD163 with the corresponding exon of human CD163-like 1 ( hCD163L1 ) using a CRISPR/Cas9 system combined with a donor vector. (ijbs.com)
  • In this study, we first generated immortalized porcine alveolar macrophage (IPAM) cell lines harboring 40-residues (residues 523-562, including R561 (arginine (R) at position 561)) deletion of CD163. (chinaagrisci.com)
  • However, in late state gestation transplacental infection to and from fetuses can occur and large scale reproductive failure may occur. (wikipedia.org)
  • In some cases, infection is manifested as an epidemic of respiratory disease or reproductive failure but in other outbreaks, infection may spread slowly. (iastate.edu)
  • Conserved Patterns of Symmetric Inversion in the Genome Evolution of Bordetella Respiratory Pathogens. (cdc.gov)
  • In addition, the reduction in CPE was abolished when the supernatants of PCV2-infected AMs were pre-treated with a mouse anti-recombinant porcine IFN-α antibody. (scienceopen.com)
  • The disease was first described as a syndrome and confused initially with several other diseases. (iastate.edu)
  • A specific causal agent could not be identified at the time, so the syndrome was called "Mystery Swine Disease. (extension.org)
  • The natural cytotoxicity receptor NKp44 (NCR2, CD336) is expressed on the majority of porcine NK cells ex vivo without stimulation. (usda.gov)
  • This syndrome results in failure during breeding and respiratory problems. (wikipedia.org)
  • Complete failure of the müllerian system results in the absence of the fallopian tubes, the uterus, the cervix, and most of the vagina (Rokitansky-Küster-Hauser syndrome). (medscape.com)
  • Although these two genotypes differ greatly in their antigenic properties and genetic content, both cause almost similar syndromes. (geneticpcr.com)
  • Porcine reproductive and respiratory syndrome causes significant losses in the pig industry due to reproductive disorders and growth retardation," said Robert Barclay, Vice President, Asia Pacific, MSD Animal Health. (merck-animal-health.com)
  • Within the swine industry, porcine reproductive and respiratory syndrome causes interstitial pneumonia of grown swine and fetal death. (wikipedia.org)
  • The report also enumerates the incidence status of porcine reproductive and respiratory syndrome and offers an insight into the pig breeding industry in China. (groupweb.com)
  • and 3) to describe the relationship between tobacco use (as well as exposure to ETS) and chronic health conditions, including respiratory and cardiovascular diseases. (cdc.gov)
  • Within the swine industry, porcine reproductive and respiratory syndrome causes interstitial pneumonia of grown swine and fetal death. (wikipedia.org)
  • Fumonisin toxicosis in swine: an overview of porcine pulmonary edema and current perspectives. (nih.gov)
  • Detection of parvovirus in porcine species by PCR. (tamu.edu)
  • This report on the porcine vaccines market analyzes the current and future scenario of the global market. (clickpress.com)
  • This study considered three primary veterinary practice categories: swine exclusive veterinary practitioner, large animal practitioner, which corresponds to veterinarians that work predominantly with food animals including but not exclusively porcine, and mixed animal practitioner, which corresponds to veterinarians working with companion and food animals. (frontiersin.org)
  • Our results indicate that animal health management practices, herd/flock size, and experience of farmers contributed significantly to the presence of animal health problems, in particular related to the physical, respiratory and digestive systems. (springer.com)
  • This report on the global porcine vaccines market comprises an elaborate executive summary, which includes market snapshot that provides information about various segments. (clickpress.com)
  • The report also profiles major players in the global porcine vaccines market based on various attributes such as company overview, financial overview, product portfolio, business strategies, and recent developments. (clickpress.com)
  • This section also provides market attractiveness analysis, in terms of country, and market share analysis, by key players, thereby presenting a thorough analysis of the overall competition scenario in the global porcine vaccines market. (clickpress.com)
  • In this context, we investigated the role of male reproductive organs in the transmission of ASF. (mdpi.com)