• A genome scan of autosomal markers (687 microsatellites and 203 insertions/deletions) on 952 individuals from 41 Pacific populations now provides the basis for understanding the remarkable nature of Melanesian variation, and for a more accurate comparison of these Pacific populations with previously studied groups from other regions. (nih.gov)
  • Genetic diversity within individual Pacific populations is shown to be very low, while differentiation among Melanesian groups is high. (nih.gov)
  • The former "East Asian" ancestral proportion in Melanesian populations converted almost entirely to "Polynesian" in this run. (nih.gov)
  • All but one of the Melanesian cluster foci are Papuan-speaking groups, primarily located in the interiors of the large islands (see Figures 7 and 8). (nih.gov)
  • In a new Science publication, researchers from the University of Washington and other institutions report detailed analyses revealing the adaptive importance of copy number variants (CNVs) acquired from Denisovan and Neanderthal ancestors, the closest relatives of modern humans, in the modern-day Melanesian population. (pacb.com)
  • Specifically, the most common ancestry groupings were Oceanic (Melanesian and Papuan) and Eastern Asian (specifically Han Chinese). (frontiersin.org)
  • An indication for post-Toba is haplo-group L3, that originated before the dispersal of humans out of Africa, and can be dated to 60,000-70,000 years ago, "suggesting that humanity left Africa a few thousand years after Toba. (wikipedia.org)
  • If true, this may "explain the apparent bottleneck in human populations that geneticists believe occurred between 50,000 and 100,000 years ago" and the relative "lack of genetic diversity among humans alive today. (wikipedia.org)
  • The study , published in the journal Science , reveals that no genetic exchange took place between the tiny extinct hominin species Homo floresiensis , which once inhabited Flores, and the ancestors of a group of extremely short-statured humans who live there today. (cosmosmagazine.com)
  • As is common in these groups, the Rampasasan genomes include small amounts of DNA from Neanderthals and Denisovans, who were archaic humans. (cosmosmagazine.com)
  • Here, we examine the relationship between recombination rate and population differentiation in humans by analyzing two uniformly-ascertained, whole-genome data sets. (blogspot.com)
  • The Y-chromosome Haplogroup C-M130, as seen, for example, in the Semang of Malaysia, and Haplogroup D-M174 among Andaman Islanders, are more prominent among Negritos than the general populations surrounding them. (wikipedia.org)
  • These relationships are often weak, depend on the characteristics of the study population and are usually strongly confounded by obesity and age. (edu.au)
  • In the present study four different datasets were used (Australian Aboriginal people (N=675), Torres Strait Islanders (N=369), African women (N=94) and Caucasian women (N=112)) and showed very weak correlations in all groups after statistical adjustments for age and obesity (ranging from r=-0.04 to 0.13). (edu.au)
  • 40 years) and partial correlations were performed within each age group whilst adjusting only for obesity. (edu.au)
  • This pattern cannot be explained by the mutagenic properties of recombination and instead must reflect the impact of selection in the last 100,000 years since human continental populations split. (blogspot.com)
  • There is barley, wheat, and lentil in wild (Paleolithic age) form, but also as cultivars, which suggests that these people had discovered cultivation as the result of millennia-long efforts and not as the result of population movements from the Near East. (blogspot.com)
  • In unsupervised analyses, a Sardinian-specific ancestry component correlates with shared drift parameters with both the Neolithic farmers and Paleolithic hunter-gatherers, and is consistent with supervised estimates of ancestry proportions in which the Ogliastra individuals have higher Neolithic farmer and Paleolithic hunter-gatherer ancestries, while individuals from the rest of the island show an infusion of the pastoralist ancestry. (blogspot.com)
  • Additionally, the most commonly associated AMD-risk SNP, CFH rs1061170 (Y402H), was also seen at a much lower frequency in the Korean and Timorese populations than in the assessed Caucasian populations (C ~7 vs. ~40%, respectively). (frontiersin.org)
  • Even though conclusive findings regarding the relationship between insulin and blood pressure (BP) have been made, several papers still report on finding weak or non-existing relationships in various population groups. (edu.au)
  • 2013) describe three scenarios regarding the bringing together of the two groups: Migrations before the development of agriculture (8,000-9,000 years before present BP). (wikipedia.org)
  • Y-chromosomal sequencing and screening reveal both stability and migrations in North Eurasian populations. (blogspot.com)
  • Diabetes is more common in Aborigines than in other Australian populations, even in groups that have lived in contact with Europids for 150 years. (edu.au)
  • The same could be said for the total Australian population of Italian ancestry, with 279,112 of the 916,121 (30.4%) listed as Melbournian residents, which is the highest Italian population in Australia and the Oceanic continent per city. (wikipedia.org)
  • The ancient samples from the Yamnaya archaeological culture are located on this eastern branch, showing that the paternal descendants of the Yamnaya population - in contrast to the published autosomal findings - still live in the Pontic steppe and were not an important source of paternal lineages in present-day West Europeans. (blogspot.com)
  • in all other populations concerned sampling concerned individuals born in the corresponding geographical regions' (p. 934). (heroicage.org)
  • I am currently doing a post-doc with Flora Jay, where we develop deep learning methods for bacterial population genomics. (smbe.org)
  • It also shows how textured human population variation can be in particular circumstances. (nih.gov)
  • The population who created these tools is not know with certainty as no human remains were found. (wikipedia.org)
  • Visscher agrees, and says that new findings are a good example of how human adaption works by exploiting genetic variations available within a population. (cosmosmagazine.com)
  • In the mid-1980s, molecular anthropology emerged as a complementary approach that exploits the genetic diversity of contemporary human groups to understand their history and genetic makeup [ 6 ]. (royalsocietypublishing.org)
  • establishing that this population isolate is able to identify both common and rare variants associated with complex phenotypes that may be difficult to study in larger but more heterogeneous populations. (biomedcentral.com)
  • The characteristics of populations and individuals across which health inequities may exist are multifactorial and may interact with each other. (biomedcentral.com)
  • This mutation is nearly absent in individuals of Asian, Oceanic, Native American or African decent (except African-Americans). (heroicage.org)
  • We find that population differentiation as assessed by inter-continental F ST shows negative correlation with recombination rate, with F ST reduced by 10% in the tenth of the genome with the highest recombination rate compared with the tenth of the genome with the lowest recombination rate (P≪10 −12 ). (blogspot.com)
  • The Italian community of Melbourne is the second largest ethnic group in Greater Melbourne, Australia, second to the Anglo-Celtic Australians ethnic group. (wikipedia.org)
  • Being overweight or obese is perceived with least accuracy by Aboriginal males of the four ethnicity/gender groups. (edu.au)
  • Aggregated data paint the appearance of a healthier profile than when data are disaggregated by ethnic group, gender, or immigration history. (elsevier.com)
  • We observed that the third leading cause of blindness in the world, age-related macular degeneration (AMD), occurs at a very low documented frequency in a population-based cohort from Timor-Leste. (frontiersin.org)
  • These results were analyzed with results previously obtained from Iceland, Orkney, and other European groups. (heroicage.org)
  • Patterns of Population Variation in Two Paleopolyploid Eudicot Lineages Suggest That Dosage-Based Selection on Homeologs Is Long-Lived" (Yue Hao, Jacob D Washburn, Jacob Rosenthal, Brandon Nielsen, Eric Lyons et al . (smbe.org)
  • Genetic studies support the endosymbiotic theory according to which mitochondria and related organelles developed from members of this group. (wikipedia.org)
  • Studies in osteology, cranial shape and dental morphology have connected the Semang to Australoid populations, but the Andamanese to Afrians in craniometry and to South Asians in dental morphology, and Philippine negritos to Mongoloid Southeast Asians. (wikipedia.org)
  • Genetic studies on Philippine Negritos, based on polymorphic blood enzymes and antigens, showed that they were similar to their surrounding populations. (wikipedia.org)
  • There is reason to suspect the Mamusi were originally a Papuan-speaking group (perhaps Ata speakers) who adopted an Oceanic language . (nih.gov)
  • Organisms, and populations of organisms, are dependent on their environmental interactions both with other living things and with nonliving factors. (cleanet.org)
  • Nationwide registers in Finland were used to compare the cause-specific mortality in 66 881 patients versus the total population (5.2 million) between 1996, and 2006, and to link these data with the use of antipsychotic drugs. (arctichealth.org)