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  • complicated diabetic foot
  • The main objective of the proposed research study is to determine the potential utilization of [18-F] Fluorodeoxyglucose (FDG) positron emission tomography (PET) in patients with complicated diabetic foot, especially in the diagnosis or exclusion of osteomyelitis in this setting. (clinicaltrials.gov)
  • EPCs
  • PGC-1α ablation in KO rescued the defective EPCs differentiation in DM, most notably PB-MNCs formation of dEPC colonies, the known vasculogenic population. (ahajournals.org)
  • PGC-1α mediates the vasculogenic differentiation defect of circulating EPCs in T1 and T2 DM, in sharp contrast to the anti-migratory effect of EC PGC-1α in mediating diabetic angiostasis. (ahajournals.org)
  • amputations
  • This is a pilot study examining tendon collagen, collagen cross-linking, and markers of tendon extracellular matrix metabolism in the Achilles tendon of diabetic patients with ulcerations and amputations of the lower extremity. (clinicaltrials.gov)
  • Prevalence
  • 12 Diabetic kidney diseases is also becoming an increasingly important cause of morbidity and mortality worldwide owing to an increasing prevalence of type 2 DM associated with metabolic derangement and obesity. (mrimsjournal.com)
  • The prevalence of T2DM varies among different ethnic populations, with the highest rate found in Pima Indians (as high as ~50%) [ 2 ]. (medsci.org)
  • The crude prevalence rate of diabetes in urban areas is about 9% and in rural areas, has increased to around 3% of the total population [ 1 ]. (alliedacademies.org)
  • type
  • Obesity is the most prominent risk factor for GDM and type 2 diabetes in prior GDM and is linked to inflammatory processes and angiopathy, increasing the cardiovascular risk ( 5 , 23 , 24 ). (diabetesjournals.org)
  • RESEARCH DESIGN AND METHODS -We measured BFVs in 28 type 2 diabetic and 22 control subjects (aged 62.3 ± 7.2 years) using transcranial Doppler ultrasound during baseline, hyperventilation, and CO 2 rebreathing. (diabetesjournals.org)
  • Group II: Consisted of 26 people of the 'Diabetic club' with type 2 diabetes who came for their monthly FPG check. (alliedacademies.org)
  • vasculopathy
  • PTERIN METABOLISM AND DIABETIC VASCULOPATHY The number of diagnosed and un-diagnosed cases of diabetes in the United States is expected to double over the next twenty-five years. (ufl.edu)
  • cohort
  • RESEARCH DESIGN AND METHODS - This population-based cohort study took place in the three Danish counties of North Jutland, Viborg, and Aarhus between 1991 and 2003. (diabetesjournals.org)
  • An age-, sex-, and glucose tolerance-stratified sample (n=631) of a population-based cohort aged 50 to 75 years was followed prospectively for 5 years. (ahajournals.org)
  • Hypertension
  • Hypertension and diabetes are widespread diseases in our modern society and due to the comfortable, but often unhealthy 'western world' lifestyle, the population suffering from its consequences is constantly growing. (clinicaltrials.gov)
  • macro
  • Using a combination of cellular, molecular and physiological approaches we characterized the mechanisms involved in the regulation of pterin metabolism and the consequences on endothelial NO and ROS signaling as it pertains to the pathogenesis of diabetic macro- and micro-angiopathies. (ufl.edu)
  • pathogenesis
  • It is generally recognized that retinal vascular damage is prominent in the pathogenesis and clinical features of DR. Previous studies suggest that choroidal angiopathy is also associated with DR, for example, delayed choroidal vascular filling 3 , 4 and reduction in choroidal blood flow and volume. (arvojournals.org)
  • oxidative
  • 26 diabetes patients were compared with 21 age matched non-diabetic healthy controls for Fasting plasma glucose (FPG), salivary glucose (SG), salivary pH (SpH), Oral health status and markers of oxidative stress in saliva namely Thiobarbituric Acid Reactive substance (TBARS) or Malondialdehyde (MDA) and Total antioxidant activity (AOA). (alliedacademies.org)
  • mice
  • 0.05 versus WT diabetic mice). (ahajournals.org)
  • In this study, we used a combination of the herpes simplex virus thymidine kinase (HSVtk) gene, a suicide gene, and ganciclovir (GCV) to control the proliferation and functioning of insulin-secreting cells after transplantation in diabetic mice. (readbyqxmd.com)
  • Specifically, using a gene therapy approach we demonstrated that over-expression of DHFR in the aorta of diabetic mice significantly improved endothelial-dependent relaxation. (ufl.edu)
  • Study
  • This study was examined whether Oryeongsan attenuate high-glucose (HG)-promoted rat mesangial cell fibrosis and matrix accumulation, major features of diabetic glomerulosclerosis. (biomedcentral.com)
  • Another study evaluated the cognitive functions and found that the diabetic patients thought processing and execution were low. (thefreelibrary.com)
  • Considering the significant effect of T2D on brain structure and functions, cognitive dysfunction is assessed and compared between the controlled and uncontrolled diabetic patients in this study. (thefreelibrary.com)