• HMGCS2 protein expression is down-regulated preferentially in moderately and poorly differentiated carcinomas. (aacrjournals.org)
  • The TMAs contained 86 well/moderately differentiated and 27 poorly differentiated/undifferentiated carcinomas. (nih.gov)
  • The incidence of calretinin expression was 15% in poorly differentiated/undifferentiated carcinomas (vs. 6% in well/moderately differentiated carcinomas, p=0.03). (nih.gov)
  • New insights emerged last decade that enriched our knowledge regarding the biological behavior of appendiceal neuroendocrine tumors (NETs), which range from totally benign tumors less than 1cm to goblet cell carcinomas which behave similarly to colorectal adenocarcinoma. (wjgnet.com)
  • Poorly differentiated carcinomas of the thyroid are frequently anti-thyroglobulin negative. (novusbio.com)
  • However, adenocarcinomas of the lung, and occasional breast, transitional cell and pancreatic carcinomas had moderate or high levels of HE4 expression. (nature.com)
  • Molecular and cytogenetic studies in the diagnosis of patients with poorly differentiated carcinomas of unknown primary site. (medscape.com)
  • Approximately 80% of all pancreatic cancers are adenocarcinomas, with only 2% of exocrine pancreatic tumors diagnosed as benign. (medscape.com)
  • Differential diagnoses include poorly differentiated adenocarcinomas, solid pseudopapillary tumors, pancreatic carcinoma, pancreatic neuroendocrine tumors and autoimmune pancreatitis. (orpha.net)
  • Adenocarcinomas, which may occur as primary tumors or rarely reflect metastasis from intestinal carcinoma. (msdmanuals.com)
  • 40% of patients, tumors recur at the same or another site in the bladder, particularly if tumors are large or poorly differentiated or if several tumors are present. (msdmanuals.com)
  • A 76‐year‐old woman received adjuvant durvalumab for Stage IIA pT2aN1M0 (American Joint Committee on Cancer, Seventh edition) poorly differentiated lung adenocarcinoma. (doaj.org)
  • Furthermore, anti-thyroglobulin, combined with anti-TTF1, can be a reliable marker to differentiate between primary thyroid and lung neoplasms. (novusbio.com)
  • This report documents the case of a 57‑year‑old male patient initially diagnosed with non‑metastatic lung adenocarcinoma, who presented with abdominal pain 6 months later. (spandidos-publications.com)
  • The patient was diagnosed with lung adenocarcinoma (pT4N2M0 stage IIIB) ( 7 ). (spandidos-publications.com)
  • Keywords: Diffuse cystic lesion, Upper body computed tomography, Lung adenocarcinoma Background Diffuse cystic lung illnesses (DCLDs) certainly are a band of pathophysiologically heterogenous procedures characterized by the forming of multiple thin-walled cystic lesions in the lung parenchyma [1]. (mingsheng88.org)
  • [ 3 , 4 ] The term "pseudomesotheliomatous carcinoma" was first applied by Harwood and colleagues in 1976 to 6 cases of peripheral lung adenocarcinoma that closely mimicked mesothelioma. (medscape.com)
  • Part of the process that helped the clinicians determine this case of early-stage (ES) NSCLC was an endobronchial ultrasound-guided transbronchial needle aspiration that revealed "poorly differentiated lung adenocarcinoma with positive staining for TTF-1 in both the lung mass and right station four (4R) lymph node, which confirmed pathologic N2 staging. (medpagetoday.com)
  • We describe the case of 61 year-old patient with primary adenocarcinoma of the lung , presenting with melaena as the first manifestation of small bowel metastasis. (ispub.com)
  • Histological examination and immunohistochemical staining of the biopsy specimen strongly supported the diagnosis of metastatic lung adenocarcinoma. (ispub.com)
  • We present a case of a 61 year old patient with upper gastrointestinal bleeding due to duodenal metastases from a primary adenocarcinoma of the lung with secondary deposits in the abdominal lymph nodes. (ispub.com)
  • Pulmonary carcinoids are well differentiated low to intermediate grade lung neuroendocrine tumours (LNETs), that belong to the group of lung neuroendocrine neoplasms which also include highly aggressive lung neuroendocrine carcinomas (LNECs). (who.int)
  • The images in the slide are of cytologic samples from fine-needle aspiration (FNA) of pancreatic adenocarcinomas: (A) well-differentiated tumor, (B) moderately differentiated tumor, (C) moderately to poorly differentiated tumor, and (D) poorly differentiated tumor. (medscape.com)
  • Pancreatic ductal adenocarcinoma is one of the most common causes of "peritoneal carcinomatosis" and has an insidious growth pattern. (nih.gov)
  • In this study, we explored the incidence of calretinin expression in pancreatic ductal adenocarcinoma. (nih.gov)
  • Pancreatic ductal adenocarcinomas, especially when poorly differentiated/undifferentiated, may be diffusely and strongly positive for calretinin creating a potential diagnostic challenge with malignant mesothelioma. (nih.gov)
  • If the diagnosis of pancreatic ductal adenocarcinoma is considered, ductal differentiation can be demonstrated by using additional immunohistochemical markers such as mucin-related glycoproteins (MUC1, MUC5AC) and/or oncoproteins (CEA, B72.3, CA125). (nih.gov)
  • Olaparib, a poly (ADP-ribose) polymerase (PARP) inhibitor, is used for maintenance therapy in pancreatic adenocarcinoma. (medscape.com)
  • Olaparib has US Food and Drug Administration (FDA) approval for adults with germline BRCA -mutated metastatic pancreatic adenocarcinoma whose disease has not progressed on at least 16 weeks of a first-line platinum-based chemotherapy regimen. (medscape.com)
  • It is indicated for maintenance treatment of adults with deleterious or suspected deleterious gBRCAm metastatic pancreatic adenocarcinoma whose disease has not progressed on at least 16 weeks of a first-line platinum-based chemotherapy regimen. (medscape.com)
  • Gross section of an adenocarcinoma of the pancreas measuring 5 × 6 cm resected from the pancreatic body and tail. (medscape.com)
  • See also Pancreatic Adenocarcinoma Imaging: What You Need to Know , a Critical Images slideshow, to help identify which imaging studies to use to identify and evaluate this disease. (medscape.com)
  • With a prevalence of 80-85%, ductal adenocarcinomas are far more common than all other histologic subtypes of pancreatic cancer. (medscape.com)
  • [2] Histologically, most pancreatic adenocarcinomas are moderately to poorly differentiated. (medscape.com)
  • Mutations in which of the following genes are commonly found in pancreatic adenocarcinoma? (medscape.com)
  • Mutations in all of the genes listed in slide 4 are found in pancreatic adenocarcinoma. (medscape.com)
  • [3] A general rule for the genetic onset of pancreatic cancer is that multiple combinations of genetic mutations are present in adenocarcinomas. (medscape.com)
  • Accurate Prognosis Prediction of Pancreatic Ductal Adenocarcinoma Using Integrated Clinico-Genomic Data of Endoscopic Ultrasound-Guided Fine Needle Biopsy. (cdc.gov)
  • In this report, we highlight an unusual site of metastasis of an endometrial adenocarcinoma to the small intestine. (karger.com)
  • I am trying to figure out what ICD 9 code to use for poorly differentiated ductal adenocarcinmoa of the breast. (aapc.com)
  • Answer: A. Ductal adenocarcinoma. (medscape.com)
  • Most ductal adenocarcinomas are tough and gritty gray-white clumps that mainly metastasize in the head of the pancreas. (medscape.com)
  • Cabometyx is indicated for the treatment of adult and pediatric patients 12 years of age and older with locally advanced or metastatic differentiated thyroid cancer (DTC) that has progressed following prior VEGFR-targeted therapy and who are radioactive iodine-refractory or ineligible. (pharmaceutical-technology.com)
  • Cabometyx is indicated as monotherapy for the treatment of adult patients with locally advanced or metastatic differentiated thyroid carcinoma (DTC), refractory or not eligible to radioactive iodine (RAI) who have progressed during or after prior systemic therapy. (pharmaceutical-technology.com)
  • However, a substantial proportion of gastric adenocarcinomas are advanced or metastatic disease at the time of diagnosis. (biomedcentral.com)
  • The tumor was completely resected, the pathological diagnosis being adenocarcinoma, and small clump of cancer cells having been found in the muscularis propria (pathological stage T2N0M0 (AJCC classification), pathological effect grade 2) (Fig. 2 ). (springeropen.com)
  • It was decided to perform a tumor excision by neurosurgery, whose pathological anatomy study revealed metastatic adenocarcinoma to the brain. (scielo.org.pe)
  • TBCB demonstrated badly differentiated adenocarcinoma and vascular tumor emboli (Fig.?2 d and c. (mingsheng88.org)
  • A tumor, "poorly-differentiated non-small cell adenocarcinoma. (mmj.vegas)
  • The index case is being presented for its rarity and probable poor outcome in young patients and to stress on the fact that the possibility of primary prostatic adenocarcinoma should be investigated in a male presenting with bone metastasis irrespective of the age. (jpalliativecare.com)
  • The establishment, characterization, and tumorigenicity of a new epithelial cell line (PC-3) from a human prostatic adenocarcinoma metastatic to bone is reported. (scienceopen.com)
  • Pathological examination of an open muscle biopsy showed a poorly differentiated adenocarcinoma, supporting a diagnosis of gastric cancer metastases in multiple skeletal muscles. (springeropen.com)
  • DCLDs are the effect of a malignant procedure seldom, that are supplementary to metastases from adenocarcinomas from the gastrointestinal system [2, 3] and sarcomas of varied cell types [4, 5]. (mingsheng88.org)
  • Fine-needle aspiration cytology of the nodule revealed it to be metastasis from gastric adenocarcinoma. (lww.com)
  • This case is reported due to the rarity of cutaneous metastasis at multiple sites from a highly aggressive adenocarcinoma in a young patient, to emphasize the importance of cutaneous metastasis as a poor prognostic sign in patients with a history of cancer. (lww.com)
  • Postoperative pathology indicated infiltrating adenocarcinoma (right upper lobe mass) with poor differentiation and lymph node metastasis. (spandidos-publications.com)
  • A biopsy was taken which came out to be poorly differentiated adenocarcinoma. (lww.com)
  • c) Esophagogastroduodenoscopy shows an ulcer at the ampulla of Vater, and the biopsy results of the ulcer indicate adenocarcinoma. (hindawi.com)
  • Biopsy results from the ulcer indicated adenocarcinoma. (hindawi.com)
  • A punch biopsy of the lesion was performed and revealed a poorly differentiated adenocarcinoma in the superficial and deep dermis. (aafp.org)
  • The patient had an incidental finding of a mass on a chest x-ray, which CT-guided biopsy later confirmed to be a poorly differentiated adenocarcinoma. (ctsnet.org)
  • Volatile aldehydes are enriched in esophageal adenocarcinoma (EAC) patients' breath and could improve early diagnosis, however the mechanisms of their production are unknown. (nature.com)
  • Better survival was observed in patients with early stage and well differentiated tumours at diagnosis. (who.int)
  • Adenocarcinoma accounts for the majority of gastric cancer diagnoses, and patients with gastric adenocarcinoma often experience relatively short survival times. (biomedcentral.com)
  • One third of patients with cancer of unknown primary origin have poorly or undifferentiated carcinoma. (medscape.com)
  • Arrington AK, Nelson R, Patel SS, Luu C, Ko M, Garcia-Aguilar J, Kim J. Timing of chemotherapy and survival in patients with resectable gastric adenocarcinoma. (wjgnet.com)
  • Metastatic Adenocarcinoma of Prostate in a 28-Year-Old Male: The outcome is poor in young patients? (jpalliativecare.com)
  • Current study aimed to develop and validate prognostic nomograms for patients with metastatic gastric adenocarcinoma treated with palliative gastrectomy. (biomedcentral.com)
  • The development dataset comprised 1186 patients from the Surveillance, Epidemiology, and End Results Program who were diagnosed with metastatic gastric adenocarcinoma in 2004-2011, while the validation dataset included 407 patients diagnosed in 2012-2015. (biomedcentral.com)
  • Our survival nomograms for patients with metastatic gastric adenocarcinoma undergoing palliative gastrectomy can assist surgeons in treatment decision-making and prognostication. (biomedcentral.com)
  • Adenocarcinomas of other-than-thyroid origin do not react with this antibody. (novusbio.com)
  • Poorly Differentiated and Anaplastic Thyroid Cancer: Insights into Genomics, Microenvironment and New Drugs. (cdc.gov)
  • The pathology study revealed a poorly differentiated adenocarcinoma. (scielo.org.pe)
  • PSA is used to screen for prostate cancer, detect recurrence of the malignancy, and evaluate specific syndromes of adenocarcinoma of unknown primary. (aafp.org)
  • As malignant cells have a tendency to round up in body fluids these non-epithelial neoplasms can therefore mimic reactive mesothelial cells and metastatic adenocarcinoma. (cytojournal.com)
  • Majority are well differentiated and mimic proliferative endometrial glands and, as such, are referred to as endometrioid carcinoma. (slideserve.com)
  • Rarely, adenocarcinomas arise within endometrial polyps. (slideserve.com)
  • Metastatic adenocarcinoma presenting as isolated axillary lymphadenopathy in women is usually a manifestation of an occult breast primary cancer . (medscape.com)
  • Gastric adenocarcinoma is one of the common causes of cancer death in the world. (lww.com)
  • AFP and β-hCG also may be useful in evaluating potential origins of poorly differentiated metastatic cancer. (aafp.org)
  • RÉSUMÉ Le taux de survie à cinq ans chez les femmes atteintes d'un cancer du sein en Jordanie et certains des facteurs ayant eu une influence sur la survie ont été mesurés. (who.int)
  • Toutes les femmes jordaniennes chez lesquelles un nouveau diagnostic de cancer du sein avait été posé en 1997-1998 ont été incluses. (who.int)
  • Although gastric adenocarcinoma is common in middle- and old-aged population, it is rare in young people. (lww.com)
  • The most common AIS was the typical type (41 cases, 67.2%) among all cytologically-diagnosed AIS or adenocarcinoma cases (61 cases). (cytojournal.com)
  • typical type (well-differentiated AIS), polymorphic type (poorly differentiated AIS), and mixed typical and polymorphic type. (cytojournal.com)
  • Intestinal-type poorly differentiated gastric adenocarcinoma with microsatellite instability and defective DNA mismatch repair proteins expression. (embl-heidelberg.de)