Disease SusceptibilityPolymorphism, GeneticGenetic Predisposition to DiseaseAutoimmune DiseasesPolymorphism, Single NucleotideGenotypeAllelesGene FrequencyHaplotypesCase-Control StudiesMicrobial Sensitivity TestsGenetic VariationHLA-DRB1 ChainsAnti-Bacterial AgentsAsian Continental Ancestry GroupPhenotypePolymerase Chain ReactionLinkage DisequilibriumGenetic Association StudiesGenome-Wide Association StudyHLA-DR AntigensRisk FactorsMutationGenetic MarkersLupus Erythematosus, SystemicImmunity, InnateGenetic LinkageArthritis, RheumatoidAutoimmunityChromosome MappingMice, Inbred C57BLAutoantibodiesDrug Resistance, MicrobialMolecular Sequence DataAge of OnsetPromoter Regions, GeneticHomozygoteEuropean Continental Ancestry GroupDisease Models, AnimalDrug Resistance, BacterialBase SequenceSequence Analysis, DNADiabetes Mellitus, Type 1HeterozygoteEpistasis, GeneticCulture MediaGenome, HumanGenetic LociHLA-DQ AntigensModels, GeneticAutoantigensMicrosatellite RepeatsPharmacogeneticsEncephalomyelitis, Autoimmune, ExperimentalTime FactorsOdds RatioCohort StudiesHLA-DQ beta-ChainsMethylenetetrahydrofolate Reductase (NADPH2)ChinaPedigreeCrohn DiseaseSpecies SpecificityDNA PrimersNod2 Signaling Adaptor ProteinCatechol O-MethyltransferasePolymorphism, Single-Stranded ConformationalT-LymphocytesAmino Acid SequenceJapanQuantitative Trait LociChromosomes, Human, Pair 6Mice, Inbred StrainsPolymorphism, Restriction Fragment LengthComplement C4aHLA-DR3 AntigenMultiple SclerosisPlant DiseasesGenes, MHC Class IIGenetic TestingHLA AntigensDNAMajor Histocompatibility ComplexAmino Acid SubstitutionGlutathione TransferaseEscherichia coliDNA Mutational AnalysisCytokinesGenetics, PopulationMice, KnockoutAryl Hydrocarbon HydroxylasesExonsCrosses, GeneticMice, Inbred BALB CGenotyping TechniquesHIV-1Peptidyl-Dipeptidase AGene Expression RegulationLymphocyte ActivationGenetic Diseases, Inborn