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  • genetic
  • Its goal is to act as a single database that contains all identified genetic variation, which can be used to investigate a wide variety of genetically based natural phenomenon. (wikipedia.org)
  • base
  • For example, a single-base mutation in the APOE (apolipoprotein E) gene is associated with a higher risk for Alzheimer's disease. (wikipedia.org)
  • human
  • As such, any related group of haplogroups may be precisely modelled as a nested hierarchy, in which each set (haplogroup) is also a subset of a single broader set (as opposed, that is, to biparental models, such as human family trees). (wikipedia.org)
  • approximately
  • The Glu504Lys single nucleotide polymorphism (SNP) of ALDH2 gene, which is found in approximately 40% of the East Asian populations, causes defect in the enzyme activity of ALDH2, leading to alterations in acetaldehyde metabolism and alcohol-induced "flushing" syndrome. (hindawi.com)
  • different
  • The Glu504Lys single nucleotide polymorphism (SNP) of ALDH2 gene, which occurs with an incidence of 35-57% in different East Asian subpopulations, causes defect in the enzyme activity of ALDH2, leading to alterations in acetaldehyde metabolism and markedly reduced alcohol tolerance [ 3 , 4 ]. (hindawi.com)
  • allelic
  • We thus conclude that differently from HLA-A, for which supertype and allelic variation show similar patterns of nucleotide diversity within and between populations, HLA-B has likely evolved through specific adaptations of its B pocket to local pathogens. (springer.com)
  • Probe
  • Multiplex ligation-dependent probe amplification (MLPA) is a variation of the multiplex polymerase chain reaction that permits amplification of multiple targets with only a single primer pair. (wikipedia.org)
  • Conclusion
  • The important conclusion of this subanalysis is that no single baseline factor reliably characterizes the overall survival subgroups defined as early deaths in less than 3 months. (ascopost.com)