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  • SNPs
  • Furthermore, the combined effect of single nucleotide polymorphisms (SNPs) rs2073618 and rs3134069 on the DR was stronger than that of each SNP alone. (hindawi.com)
  • In single-SNP association tests, the SNPs rs11647932, rs11645214, and rs6499323 located at 16q22.1 under the additive-effect disease model were significantly associated with an approximately 2-fold increased risk of DN. (biomedcentral.com)
  • Purpose: Discovery of single nucleotide polymorphisms (SNPs) that predict a patient's risk of docetaxel-induced neuropathy would enable treatment individualization to maximize efficacy and avoid unnecessary toxicity. (regenerativemedicine.net)
  • genotype
  • Meanwhile, the GGT1 genotype was not associated with the risk of DR, although it affected the principal factors involved in the risk of DR, and a low HDL-C level was also found to be a risk factor for DR only in G allele carriers. (biomedcentral.com)
  • The AG genotype had significantly lower levels of hs-CRP (mg/l), and was protected from the presence of diabetic foot in comparison with GG homozygotes, AG:31(26.7) GG:84(37.8), (OR 0.562, 95%CI 0.322-0.983, p=0.043). (openarchives.gr)
  • Logistic regression analysis demonstrated that the carriers of the CC genotype had a 2.2 higher risk for DR than those with either the CG genotype or the GG genotype (codominant model for rs2073618). (hindawi.com)
  • variant
  • Surveying a small set of CAFs from breast cancer biopsies, we found that a relatively common single nucleotide polymorphism, which results in the expression of a GPER variant with the amino acid substitution P16L, is associated with the nuclear localization of GPER. (regenerativemedicine.net)
  • factors
  • respectively), and a significant interactive effect between these factors was found on the risk of a high baPWV and DR. The HDL-C level at baseline was a significant predictor of a high baPWV only in G allele carriers according to the ROC analysis. (biomedcentral.com)
  • Risk factors for hemiretinal vein occlusion comparison with risk factors for central duphastton branch retinal vein occlusion they eye disease case-control study. (forvps.ru)
  • common
  • Gagné JF, Montminy V, Belanger P, Journault K, Gaucher G, Guillemette C. Common human UGT1A polymorphisms and the altered metabolism of irinotecan active metabolite 7-ethyl-10-hydroxycamptothecin (SN-38). (pharmacogenomicsguide.com)
  • clinical
  • The use of these techniques may help to identify high-risk individuals in preclinical phase who may benefit from active therapy to prevent clinical disease. (hindawi.com)