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  • tumor reini
  • Researchers at Ohio State University have now developed a new nanoparticle designed to specifically attack these tumor reinitiating cells to prevent the cancer from coming back. (medgadget.com)
  • carriers
  • Bioactive nanoparticles whose surfaces have been modified with them can be used as anti-tumor compounds, gene carriers, contrast agents that improve MRI images, and protein detectors. (news-medical.net)
  • Therefore, we expect that this study can provide valuable information for biomedical researchers to develop optimized nanoparticles as drug or gene carriers for retinal and optic nerve disorders such as glaucoma, age-related macular degeneration, and diabetic retinopathy. (nih.gov)
  • Natural cells have erythrocyte membrane-camouflaged polymeric nano particles synthesis been explored s p case shiller national hpi rc as drug de novo pathway of nucleotide synthesis service carriers for a long period. (masterdam.info)
  • Finally, the interaction of the nanoparticles with breast cancer cells was studied utilizing fluorescence microscopy, demonstrating the potential of the nanoparticles to act as near-infrared fluorescence optical imaging agents and drug-delivery carriers. (duke.edu)
  • retinoic
  • We hypothesized that polymeric nanoparticles bearing ascorbic acid (AA) and retinoic acid (RA) will be effective in reducing inflammation and promoting SMC synthesis of the ECM proteins, collagen and elastin, thus inhibiting aneurysm formation in vivo . (ahajournals.org)
  • extract
  • After that, centrifugal separation was used to extract polymeric nanospheres of identical form and size. (phys.org)
  • This study sought to prepare a xanthones extract (81% α -mangostin and 16% γ -mangostin) in polymeric nanoparticles and to investigate its intracellular delivery and cytotoxicity toward colon cancer cells. (hindawi.com)
  • surfaces
  • Reversible and irreversible binding of CdSe-nanoparticles and nanorods to polymeric surfaces via a strong, multiple hydrogen bond (= Hamilton-receptor/barbituric acid) is described. (hindawi.com)
  • Strong binding is observed with CdSe-nanoparticles and CdSe-nanorods, whose surfaces are equipped with matching barbituric acid-moieties. (hindawi.com)
  • interactions
  • The supramolecular recognition concept overcomes the selection between larger- or smaller-sized nanoparticles by introducing directed, specific, and stronger interactions. (hindawi.com)
  • inhibition
  • The CD44 receptor competitive inhibition and the internalization pathway studies suggested that the internalization mechanism of the nanoparticles was mediated mainly by the CD44 receptors through a clathrin-dependent endocytic pathway. (dovepress.com)
  • Tub A and the active thiol derivative were potent inhibitors of tubulin polymerization, whereas CDP-TubA showed minimal inhibition, indicating that target inhibition requires release of the peptide drug from the nanoparticles. (aacrjournals.org)
  • Stability
  • Finally, stability and release studies were undertaken to ascertain further the suitability of the nanoparticles as a carrier system for α- and β-arbutin. (springer.com)
  • peptide
  • Analysis showed that when the cell-penetrating peptide called R8 - an octapeptide made from eight arginine amino acids - was attached to the nanoparticles, they were taken up by cells within five hours and had no toxic or inflammatory effect on the cells even after three days. (news-medical.net)
  • size
  • The size obtained for the alpha nanoparticles (α-arbutin CSNPs) ranges from 147 to 274 d.nm, with an increase in size with increasing alpha arbutin concentration. (springer.com)
  • β-arbutin nanoparticles (β-arbutin CSNPs) size range was from 211.1 to 284 dn.m. (springer.com)
  • Both can be achieved by carefully adjusting the size and adsorption energy between the interfacial contact and the nanoparticles surface. (hindawi.com)
  • Examples of such processes have been described via size-selective control of nanoparticle-binding at liquid/liquid-interfaces as reported by Duan et al. (hindawi.com)
  • For nanosystems of iron and other metals and their oxides in polymeric matrices, the pronounced size effects were observed. (foresight.org)
  • doxorubicin
  • A large dose of doxorubicin, a common chemo drug, is encapsulated within the nanoparticles. (medgadget.com)
  • Doxorubicin-loaded protease-activated near-infrared fluorescent polymeric nanoparticles for imaging and therapy of cancer. (duke.edu)
  • The chemotherapeutic drug doxorubicin was encapsulated in the core of nanoparticles at a loading of 3% (w:w) and controllably released over a period of 30 days. (duke.edu)
  • Conclusion:Doxorubicin-loaded, enzymatically activatable nanoparticles of less than 100 nm were prepared successfully by nanoprecipitation of copolymer blends. (duke.edu)
  • Journal
  • Effects of technical parameters on the physicochemical properties of rifampicin-containing polylactide nanoparticles," Pharmaceutical Chemistry Journal , vol. 44, no. 3, pp. 151-156, 2010. (hindawi.com)
  • In a recent article published in the journal Science and Technology of Advanced Materials, they reviewed current ways in which polymeric nanoparticles can be used to transport a type of small nanoparticles called quantum dots into cells. (news-medical.net)
  • substances
  • Polymeric nanospheres and nitrogen-containing carbon nanoparticles based on them may be used for catalysis, energy conversion and storage, purification of other substances, and so on. (phys.org)