OrthobunyavirusGenomeOutbreaks of hemorrhagic feverNucleoproteinIsolatesGenomesReassortantVirionsGenusViralRNAsReplicationHumansBataiSindbisInitiationICTVVaccinia virusAedesGeneticSerologicalArbovirusesPathogenicInfectionVectorsMolecularRecombinantEndemicMosquitoesTranscriptsSalivaMosquitoFlavivirusesSpeciesDiseasesIsolateInfectiousParticlesProteinMutant1984Activity1996ElectronIllnessTypeStrainSystemCells
Orthobunyavirus6
- Bunyamwera orthobunyavirus (BUNV) is a negative-sense, single-stranded enveloped RNA virus. (wikipedia.org)
- Bunyamwera orthobunyavirus can infect both humans and Aedes aegypti (yellow fever mosquito). (wikipedia.org)
- Reassortant viruses derived from Bunyamwera orthobunyavirus, such as Ngari virus, have been associated with large outbreaks of viral haemorrhagic fever in Kenya and Somalia. (wikipedia.org)
- In humans, Bunyamwera orthobunyavirus causes Bunyamwera fever. (wikipedia.org)
- ICTV Taxonomy history: Bunyamwera orthobunyavirus" (html). (wikipedia.org)
- Regarding Bunyamwera orthobunyavirus a particular series 5 inside HCl salt the 5? (immune-source.com)
Genome6
- The full-genome sequence showed differences from a previously reported virus isolate from a mosquito in Germany. (cdc.gov)
- For example, the Ngari virus genome consists of segments from BATV and Bunyamwera virus. (cdc.gov)
- The genome of Bunyamwera virus (BUN) consists of three segments of single-stranded RNA of negative polarity. (microbiologyresearch.org)
- The L protein of Rift Valley fever virus can rescue viral ribonucleoproteins and transcribe synthetic genome-like RNA molecules. (microbiologyresearch.org)
- Characterization of La Crosse virus small genome transcripts. (microbiologyresearch.org)
- The genome encodes for the typical five proteins found in all rhabdoviruses: nucleocapsid (N), phosphoprotein (P), matrix (M), glycoprotein (G), and polymerase (L). However, there are three additional genes, U1-U3, that encode for proteins of unknown function. (wikimili.com)
Outbreaks of hemorrhagic fever1
- Ngari virus is associated with outbreaks of hemorrhagic fever in humans and shows a clinical spectrum different from that of both parent viruses ( 2 ). (cdc.gov)
Nucleoprotein1
- The trojan replicates in lots of cell types and after uncoating the L M and S RNAs from the nucleoprotein as well as the polymerase by means of RNPs will be the layouts for the formation of two types of cRNA substances the antigenomes as well as the mRNAs. (immune-source.com)
Isolates2
- 1993. The serological comparison of tospovirus isolates from Taiwan and India with Impatiens necrotic spot virus and different tomato spotted wilt virus isolates. (esciencepress.net)
- 2003. Ultrastructural differences in mixed infections of six Turnip mosaic virus and one Ribgrass mosic virus isolates in Crucifers. (esciencepress.net)
Genomes1
- Many of these viruses have RNA genomes. (bvsalud.org)
Reassortant1
- These segments can be interchanged between viruses of the same genus, resulting in stable reassortant bunyaviruses. (cdc.gov)
Virions2
- Tibrovirus virions are enveloped, but only the morphology of Tibrogargan virus and Sweetwater branch virus have been observed by electron microscopy. (wikimili.com)
- 1995. An RNA-dependent RNA polymerase activity associated virions of tomato spotted wilt virus, a plant and insect-infecting Bunyavirus. (esciencepress.net)
Genus5
- Tibrovirus is a poorly characterized genus of viruses in the family Rhabdoviridae , order Mononegavirales . (wikimili.com)
- A genus of the family HERPESVIRIDAE, subfamily ALPHAHERPESVIRINAE, consisting of herpes simplex-like viruses. (lookformedical.com)
- Other words only begin with a capital if they are proper nouns (including host genus names but not virus genus names**) or alphabetical identifiers. (ictv.global)
- A virus name should never be italicized, even when it includes the name of a host species or genus, and should be written in lower case. (ictv.global)
- The first letters of words in a virus name, including the first word, should only begin with a capital when these words are proper nouns (including host genus names but not virus genus names) or start a sentence. (ictv.global)
Viral4
- Characterization of the 5′ and 3′ ends of the viral messenger RNAs isolated from BHK-21 cells infected with Germiston virus (Bunyavirus). (microbiologyresearch.org)
- Bunyamwera bunyavirus nonstructural protein NSs is a nonessential gene product that contributes to viral pathogenesis. (microbiologyresearch.org)
- RNA polymerase I-catalyzed expression of chimeric viral RNAs. (microbiologyresearch.org)
- By artificially expressing Sindbis virus (SINV) and chikungunya virus (CHIKV) nsP2 in mosquito cells and transgenic mosquitoes, we demonstrated a reduction in both SINV and CHIKV viral replication rates in cells following viral infection as well as reduced infection prevalence, viral titers, and transmission potential in mosquitoes. (bvsalud.org)
RNAs2
- Exogenously provided, e.g. transgene encoded, small RNAs could be used to inhibit virus replication, breaking the transmission cycle. (bvsalud.org)
- albopictus cell lines, reporter-based strategies for assessing the ability of two types of small RNAs to inhibit a chikungunya virus (CHIKV) derived target. (bvsalud.org)
Replication1
- [10] EKV-1 could not be isolated from the patient's blood sample and live replication-competent virus is not available. (wikimili.com)
Humans2
- Eastern equine encephalitis virus (EEEV) causes a rare but severe disease in horses and humans and is maintained in an enzootic transmission cycle between songbirds and Culiseta melanura mosquitoes. (bvsalud.org)
- Venezuelan equine encephalitis virus circulates in enzootic cycles between rodent hosts and mosquito vectors in Mexico, Central and South America [ 16 ] and has a complex transmission cycle involving regular mutation of the virus, facilitating transmission to humans and horses through broadening of the vector and host ranges. (biomedcentral.com)
Batai3
- We isolated Batai virus from the brain of a euthanized, 26-year-old, captive harbor seal with meningoencephalomyelitis in Germany. (cdc.gov)
- Batai virus (BATV) is a member of the Bunyamwera serogroup of orthobunyaviruses of the family Peribunyaviridae . (cdc.gov)
- Histologic analysis and fluorescent in situ hybridization (FISH) of a Batai virus BATV)-infected harbor seal, Germany, 2016. (cdc.gov)
Sindbis1
- Noncytopathic Sindbis virus RNA vectors for heterologous gene expression. (microbiologyresearch.org)
Initiation2
- DNA sequences which are recognized (directly or indirectly) and bound by a DNA-dependent RNA polymerase during the initiation of transcription. (lookformedical.com)
- Numerous viruses interfere with PABPC1 function in translation initiation. (expasy.org)
ICTV1
- International Committee on Taxonomy of Viruses (ICTV). (wikipedia.org)
Vaccinia virus2
- Characterization of Bunyamwera S RNA that is transcribed and replicated by the L protein expressed from recombinant vaccinia virus. (microbiologyresearch.org)
- Rabbitpox virus is a subspecies of VACCINIA VIRUS . (lookformedical.com)
Aedes4
- Whilst the emergence in Europe of dengue and chikungunya has been associated with Aedes aegypti and the invasive mosquito Aedes albopictus [ 2 ], for most of the equine viruses Culex mosquitoes are significantly involved in transmission. (biomedcentral.com)
- Viruses transmitted by Aedes mosquitoes are an increasingly important global cause of disease. (bvsalud.org)
- Instead, the Aedes gene product sialokinin mediated the enhancement of virus infection through a rapid reduction in endothelial barrier integrity. (bvsalud.org)
- Therapeutic strategies targeting sialokinin have the potential to limit disease severity following infection with Aedes-mosquito-borne viruses. (bvsalud.org)
Genetic3
- Deoxyribonucleic acid that makes up the genetic material of viruses. (lookformedical.com)
- Viruses whose genetic material is RNA. (lookformedical.com)
- 2002. Genetic organization of Iris yellow spot virus M RNA: indications for functional homology between the Gc. (esciencepress.net)
Serological2
- The N protein is the most abundant protein in virus particles and infected cells and, therefore, the main target in many serological and molecular diagnostics. (wikipedia.org)
- 1990. Serological differentiation of twenty of tomato spotted wilt virus. (esciencepress.net)
Arboviruses2
- Members of the species West Nile virus are arboviruses. (ictv.global)
- Patients infected with arboviruses such as Zika virus should be advised to limit activity during symptomatic illness in order to avoid exposure to mosquitoes and potential risk for human-to-arthropod transmission and subsequent local spread of disease. (medscape.com)
Pathogenic2
- The ability of a pathogenic virus to lie dormant within a cell (latent infection). (lookformedical.com)
- Multiple viruses, including pathogenic viruses, bacteriophages, and even plant viruses, cause a phenomenon termed superinfection exclusion whereby a currently infected cell is resistant to secondary infection by the same or a closely related virus. (bvsalud.org)
Infection7
- produced JEV RNA in saliva after 21 days at 18 °C. For some mosquito-virus pairs, infection and salivary RNA titres reduced over time, suggesting unstable infection dynamics. (biomedcentral.com)
- Zika virus (ZIKV) infection usually is mild and self-limited. (medscape.com)
- There are no specific FDA-approved treatment options or vaccines for treatment and prevention of Zika virus infection. (medscape.com)
- Use of nonsteroidal anti-inflammatory drugs (NSAIDs) in patients with unconfirmed Zika virus infection should be avoided since the use of such drugs in dengue fever is associated with hemorrhagic risk and risk for Reye syndrome in the pediatric population. (medscape.com)
- Expert consultation with a maternal-fetal medicine and infectious diseases specialists is advised for management of Zika virus infection during pregnancy. (medscape.com)
- The best method for preventing Zika virus infection is to avoid travel to areas with active Zika virus transmission. (medscape.com)
- Infection of the vertebrate host with these viruses is enhanced by mosquito saliva, a complex mixture of salivary-gland-derived factors and microbiota. (bvsalud.org)
Vectors1
- albopictus are the main vectors of mosquito-borne viruses of medical and veterinary significance. (bvsalud.org)
Molecular1
- Specific molecular components of the cell capable of recognizing and interacting with a virus, and which, after binding it, are capable of generating some signal that initiates the chain of events leading to the biological response. (lookformedical.com)
Recombinant2
- Experiments using a recombinant vesicular stomatitis virus expressing the EKV-1 envelope glycoprotein indicate EKV-1 has very broad tropism and can efficiently enter nearly all types of human cells. (wikimili.com)
- Experiments using a recombinant vesicular stomatitis virus expressing the EKV-2 envelope glycoprotein indicate EKV-2 has very broad tropism similar to EKV-1. (wikimili.com)
Endemic2
- Powassan virus (POWV, family Flaviviridae) is a reemerging tick-borne virus endemic in North America and Russia. (bvsalud.org)
- The three viruses investigated in the present study (VEEV, RRV, JEV) have significant impacts on the health of people and horses (summarised in [ 15 ]) in endemic areas. (biomedcentral.com)
Mosquitoes1
- Sialokinin is unique within the insect world as having a vertebrate-like tachykinin sequence and is absent from Anopheles mosquitoes, which are incompetent for most arthropod-borne viruses, whose saliva was not proviral and did not induce similar vascular permeability. (bvsalud.org)
Transcripts1
- Inhibiting host translation eventually leads to shutoff of host proteins expression and gives viruses transcripts a competitive edge for access to the cellular translation machinery. (expasy.org)
Saliva1
- Production of RNA in saliva was demonstrated at varying efficiencies for all mosquito-virus pairs. (biomedcentral.com)
Mosquito1
- is potentially an efficient laboratory vector of JEV at temperatures as low as 18 °C warrants further investigation, as this mosquito is abundant in cooler regions of Europe and is considered an important vector for West Nile Virus, which has a comparable transmission ecology. (biomedcentral.com)
Flaviviruses1
- Flavivirus and Flaviviridae ), this may lead to ambiguity because both groups of viruses could be referred to as flaviviruses. (ictv.global)
Species8
- Proteins found in any species of virus. (lookformedical.com)
- The type species of ORTHOPOXVIRUS, related to COWPOX VIRUS , but whose true origin is unknown. (lookformedical.com)
- How do I write virus, species, and other taxa names? (ictv.global)
- Names of viruses (the physical things you work with in the lab or that make you sick) are written differently than the names of species and other taxa (logical constructs that help us categorize viruses). (ictv.global)
- The species Sandfly fever Naples phlebovirus has many diverse member viruses. (ictv.global)
- A new bacteriophage, belonging to the species Salmonella virus SP6 , has been isolated. (ictv.global)
- In most texts, virus names are used much more frequently than species names and may, therefore, be abbreviated. (ictv.global)
- The order Picornavirales includes viruses infecting hosts of a range of species. (ictv.global)
Diseases3
- None of the tibroviruses, except for Bas-Congo virus, have been associated with any diseases. (wikimili.com)
- Virus diseases caused by the HERPESVIRIDAE. (lookformedical.com)
- A general term for diseases produced by viruses. (lookformedical.com)
Isolate1
- 1992. Characterization of distinct isolate of tomato spotted wilt virus TSWV. (esciencepress.net)
Infectious2
- The mechanism by which latent viruses, such as genetically transmitted tumor viruses ( PROVIRUSES ) or PROPHAGES of lysogenic bacteria, are induced to replicate and then released as infectious viruses. (lookformedical.com)
- Virus shedding is an important means of vertical transmission (INFECTIOUS DISEASE TRANSMISSION, VERTICAL). (lookformedical.com)
Particles1
- The expelling of virus particles from the body. (lookformedical.com)
Protein1
- The L-protein had high identity in the "core-polymerase domain" with the corresponding regions of other tospoviruses. (esciencepress.net)
Mutant2
- We recently described a mutant virus (BUNdelNSs) that does not express NSs but overexpresses N and grows to lower titres than wild-type (wt) BUN. (microbiologyresearch.org)
- We observed a similar scenario with mutant viruses in which the motif was present but close to the quit codon of the ORF contained in the transcribed mRNA. (immune-source.com)
19841
- Beatrice Hill virus (BHV) was isolated from a pool of biting midges (Culicoides peregrinus) in 1984 in Northern Territory, Australia. (wikimili.com)
Activity1
- Substances elaborated by viruses that have antigenic activity. (lookformedical.com)
19961
- 1996. Occurrence of tomato spotted wilt virus in vegetables and ornamentals in Greece. (esciencepress.net)
Electron1
- 1964. Electron microscopy of strain E of tomato spotted wilt virus and comments on its probable biosyntheses. (esciencepress.net)
Illness1
- Bas-Congo virus (BASV) was discovered in 2009 in the Democratic Republic of Congo in a blood sample collected from a 32-year-old male who survived a severe illness resembling hemorrhagic fever. (wikimili.com)
Type1
- Bunya: from Bunyamwera, place in Uganda, where type virus was isolated. (wikipedia.org)
Strain1
- Single letters in virus names, including alphanumerical strain designations, may be capitalized. (ictv.global)
System1
- capped terminal series of cellular origins obtained through a cap-snatching system mediated with the L RNA polymerase which possesses an endonuclease area in its N-terminal region (31). (immune-source.com)
Cells2
- We attempted virus isolation from homogenized brain in Vero cells. (cdc.gov)
- Process of growing viruses in live animals, plants, or cultured cells. (lookformedical.com)