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  • Antifungals
  • Terbinafine-loaded mats were effective against three filamentous fungal species.Among the two azole antifungals compared, the itraconazole-loaded mat was potent against Aspergillus strains.As a result, the polyenes stabilized the triple helical conformation of gelatin and the presence of gelatin decreased the hemolytic activity of polyenes. (nih.gov)
  • Biophysical and rheological measurements indicate strong interactions between polyene antifungals and gelatin matrix. (nih.gov)
  • The biocompatibility of polyene-loaded antifungals was evaluated by monitoring the cell viability of human corneal fibroblasts and human sclera fibroblasts primary cells. (nih.gov)
  • This makes polyene antifungals amphiphilic. (wikipedia.org)
  • molecule
  • A conjugated polyene is any molecule in which double bond s alternate with single bond s. (everything2.com)
  • In nonconjugated polyenes, Π electrons are localized, leading to a molecule with more energy and less stability. (everything2.com)
  • This invention relates to polyenes containing at least two ethylenically unsaturated bonds per molecule formed by reacting in substantially stoichiometric amounts, (1) a primary diamine, (2) a member of the group consisting of a benzenoid-containing dianhydride, acid anhydride and anhydride acid halide and (3) an ethylenically unsaturated alcohol. (patents.com)
  • Molecular
  • Molecular orbital theory explains conjugated polyene stability by saying that Ψ 1 , the lowest energy bonding molecular orbital of such an molecule's electron system, has a favorable bonding interaction between even the ostensibly singly bonded carbons of the system. (everything2.com)
  • DRE is the quantity which allows one to account for the effects of electron delocalization and thus serves as a measure of the stabilization of a polyenes molecular entity. (thefreedictionary.com)
  • 2. Ethylene-alpha-olefin-polyene random copolymer rubber as claimed in claim 1, wherein a Q value defined by a ratio the weight-average molecular weight number-average molecular weight of the copolymer rubber is not more than 6. (google.com)
  • amphotericin
  • The data are discussed with regard to, first, the nature of the polyene-sterol interactions which result in pore formation, and second, the functional groups on amphotericin B responsible for membrane anion selectivity. (rupress.org)
  • ethylene
  • The present invention relates to ethylene-alpha-olefin-polyene random copolymer rubber having excellent extrudability and physical properties and a method for the production thereof. (google.com)
  • It also relates to vulcanizate obtained from the ethylene-alpha-olefin-polyene random copolymer rubber. (google.com)
  • Ethylene-alpha-olefin-polyene terpolymer rubber such as ethylene-propylene-polyene terpolymer rubber ("copolymer rubber" hereinbelow) generally has excellent weathering resistance, ozone resistance, heat aging characteristic, and other characteristics and, therefore, is widely used as materials for automobiles, electric wires, buildings, and other various industrial products. (google.com)
  • Thus
  • Thus many natural dyes contain linear polyenes, e.g. beta-carotene, which is responsible for the color of carrots. (wikipedia.org)
  • The thus formed amideacid polyene either per se or after being cured in combination with a polythiol in the presence of a free radical generator will, upon heating, imidize. (patents.com)
  • free
  • For a comparison we have also determined the cytotoxicity of free polyenes with human corneal fibroblast cells (Figure 10A). (nih.gov)
  • human
  • The polyene-loaded fiber mats were noncytotoxic to primary human corneal and sclera fibroblasts. (nih.gov)