• Indeed, several roles for ENDOG have been hypothesized, including maturation of RNA primers during mtDNA replication, splicing of polycistronic transcripts and mtDNA repair. (mdpi.com)
  • Ribosome shunting allows host translational machinery to engage polycistronic transcripts similar to RIBOSOMAL FRAMESHIFTING, and use of INTERNAL RIBOSOME ENTRY SITES. (bvsalud.org)
  • The cluster genes are produced as polycistronic RNA. (wikipedia.org)
  • Only two of the 147 genes contain a TTA codon, but some effects of bldA could be traced to TTA codons in regulatory genes or polycistronic operons. (biomedcentral.com)
  • The proposed mechanism is based on the knowledge that transcription of mtDNA is polycistronic, which means that all genes encoded on the heavy and light strands are transcribed as 2 large precursor RNA strands. (medscape.com)
  • VSGS, in the bloodstream form, are expressed from specialised polycistronic, telomeric transcription units named bloodstream expression sites (BESs). (gla.ac.uk)
  • Our pioneering discovery of the polycistronic tarsal-less gene has been followed by two medically-relevant smORFs: sarcolamban and hemotin. (cabd.es)
  • 3. Tan S. A Modular Polycistronic Expression System for Overexpressing Protein Complexes in Escherichia coli. (ac.ir)
  • In particular, methods and compounds are provided for the modulation of the levels, expression, processing, or function of polycistronic pri-miRNAs. (genomeweb.com)
  • 27. Mammalian Polycistronic mRNAs and Disease. (nih.gov)
  • 1990. Human papillomavirus type 1 produces redundant as well as polycistronic mRNAs in plantar warts. (nih.gov)
  • Promoter is the site where RNA polymerase binds to perform transcription, prokaryotic operons expression helps in generation of polycistronic mRNAs, while eukaryotic operons lead to monocistronic mRNAs. (justaaa.com)
  • In bacteria, a group of metabolically related genes, with a common promoter, whose transcription into a single polycistronic MESSENGER RNA is under the control of an OPERATOR REGION . (bvsalud.org)
  • This increases promoter efficiency and results in the expression of the structural genes through the production of a polycistronic messenger RNA (mRNA). (pharmacy180.com)
  • Bacterial mRNA can be polycistronic, meaning that one mRNA codes for several proteins. (medicinembbs.org)
  • Polycistronic mRNA is present in prokaryotes and it contain many reading frames that codes for multiple proteins. (meritnation.com)
  • Translation is also a site of prokaryotic gene regulation: Excess ribosomal proteins bind the Shine-Dalgarno sequence on their own polycistronic mRNA, preventing ribosomes from binding. (pharmacy180.com)
  • Both of the mRNA 's code for protein (s), but monocistronic codes for 1 protein and polycistronic codes for more than 1 protein. (meritnation.com)
  • RT-PCR and the analysis of polar mutants showed that the Pbo cluster is organized in four transcriptional units, including one monocistronic and three polycistronic. (unavarra.es)
  • A polycistronic microRNA cluster, miR-17-92, is overexpressed in human lung cancers and enhances cell proliferation. (bvsalud.org)
  • This polycistronic way of expression occurs naturally in bacteria while in yeasts specific DNA elements are required to realize it. (tugraz.at)
  • All 2-series vectors work as single-expression vectors, as well as transfer vectors for our polycistronic system. (addgene.org)
  • The three polycistronic units were transcribed at high levels at 18 °C but not at 28 °C, whereas gene pboJ was constitutively expressed. (unavarra.es)
  • A part of the toolkit are modulesthat allow assembly of tRNA-sgRNA polycistronic units without a PCR step involved. (rothamsted.ac.uk)