Tumor Suppressor Protein p53Tumor Suppressor ProteinsGenes, Tumor SuppressorCell PolarityVon Hippel-Lindau Tumor Suppressor ProteinTumor Suppressor Protein p14ARFRetinoblastoma ProteinCell Line, TumorProto-Oncogene Proteins c-mdm2MutationMolecular Sequence DataGenes, p53Nuclear ProteinsProtein BindingNeurofibromin 2ApoptosisGene Expression Regulation, NeoplasticAdenomatous Polyposis Coli ProteinDNA-Binding ProteinsTranscription FactorsCell LineTransfectionCell CycleSignal TransductionCyclin-Dependent Kinase Inhibitor p16Genes, SuppressorUbiquitin-Protein LigasesProto-Oncogene ProteinsTumor Cells, CulturedAmino Acid SequenceCell Cycle ProteinsPTEN PhosphohydrolaseBase SequenceCyclin-Dependent Kinase Inhibitor p21Cell Transformation, NeoplasticPromoter Regions, GeneticCell ProliferationCell DivisionPhosphorylationDNA DamageNeoplasmsTranscription, GeneticNeoplasm ProteinsLigasesCyclinsE2F Transcription FactorsProteinsRepressor ProteinsProtein Structure, TertiaryRNA, MessengerDown-RegulationBlotting, WesternTranscriptional ActivationTumor Markers, BiologicalProtein-Serine-Threonine KinasesCarrier ProteinsRNA InterferenceBinding SitesGene SilencingE2F1 Transcription FactorRecombinant Fusion ProteinsSuppression, GeneticMembrane ProteinsSuppressor of Cytokine Signaling ProteinsCells, CulturedDrosophila ProteinsFibroblastsRNA, Small InterferingHeLa CellsTranscription Factor DP1Reverse Transcriptase Polymerase Chain ReactionDNA MethylationLoss of HeterozygosityGene Expression RegulationOncogene Proteins, ViralKidney NeoplasmsGene DeletionModels, BiologicalPapillomavirus E7 ProteinsCell NucleusWT1 ProteinsTrans-ActivatorsRetinoblastoma-Binding Protein 1Tumor BurdenImmunohistochemistryDNA PrimersRetinoblastoma-Like Protein p107Tumor Necrosis Factor-alphaIntracellular Signaling Peptides and ProteinsBreast NeoplasmsWilms TumorProteasome Endopeptidase ComplexMice, KnockoutDNA, NeoplasmG1 PhaseMice, NudeHypoxia-Inducible Factor 1, alpha SubunitCell AgingPhenotypeGenes, Retinoblastoma