PlaguePlague VaccineYersinia pestisPore Forming Cytotoxic ProteinsLethal Dose 50Containment of BiohazardsPrimate DiseasesSiphonapteraAntibodies, BacterialVirulence FactorsVaccines, SubunitLevofloxacinAntigens, BacterialVirulenceAdministration, IntranasalDisease OutbreaksBacterial ProteinsDisease Models, AnimalOfloxacinVaccines, AttenuatedLungMice, Inbred BALB CSurvival AnalysisVaccines, SyntheticMice, Inbred C57BLGene Expression Regulation, BacterialImmunization, PassiveCytokinesAdjuvants, ImmunologicMadagascarSpleenHistory, MedievalRodentiaDisease ReservoirsRodent DiseasesHistory, 17th CenturyHistory, 15th Century