• Streptococcus pneumoniae is the leading cause of community-acquired pneumonia in adults. (cdc.gov)
  • KENILWORTH, N.J.--(BUSINESS WIRE)-- Merck (NYSE: MRK), known as MSD outside the United States and Canada, today announced that the European Medicines Agency's Committee for Medicinal Products for Human Use (CHMP) has recommended the approval of VAXNEUVANCE™ (Pneumococcal 15-valent Conjugate Vaccine) for active immunization for the prevention of invasive disease and pneumonia caused by Streptococcus pneumoniae in individuals 18 years of age and older. (merck.com)
  • The global prevalence of pneumococcal disease, an infection caused by bacteria called Streptococcus pneumoniae , is evolving. (merck.com)
  • Streptococcus pneumoniae is a human pathogen that is responsible for causing pneumonia, otitis media, meningitis, and other infectious diseases. (mdpi.com)
  • Pneumococcal infections are caused by Streptococcus pneumoniae, a lancet-shaped, gram-positive, catalase-negative facultative anaerobe commonly referred to as pneumococcus. (medscape.com)
  • The most common cause of pneumonia is pneumococcal bacteria, Streptococcus pneumoniae accounts for 2/3 of bacteremic pneumonias. (wikipedia.org)
  • Outcomes for patients with bacteremic Streptococcus pneumoniae were significantly worse than those for patients with Legionnaires disease (LD) based on data from 106 individuals. (medscape.com)
  • Pfizer Inc. (NYSE:PFE) today announced that the U.S. Food and Drug Administration (FDA) accepted for priority review a Biologics License Application (BLA) for its 20-valent pneumococcal conjugate vaccine (20vPnC) candidate, as submitted for the prevention of invasive disease and pneumonia caused by Streptococcus pneumoniae serotypes in the vaccine in adults ages 18 years and older. (pfizer.com)
  • Pneumococcal infections are caused by Streptococcus pneumoniae (pneumococcus), a gram-positive, facultative anaerobic bacterium. (cdc.gov)
  • Among the three patients with pneumonia, two were bacteremic with Streptococcus pneumoniae, ultimately determined to be serotype 5, one of whom also had laboratory-confirmed influenza B virus by polymerase chain reaction (PCR). (cdc.gov)
  • Susceptibilidad a penicilina en cepas de Streptococcus pneumoniae aisladas en el Hospital de Puerto Montt, 1995-2003. (bvsalud.org)
  • Two isolates of streptococcus pneumoniae having different optochin susceptibilities were recovered from a blood sample of a 2-year-old boy with community-acquired pneumonia. (lookfordiagnosis.com)
  • Pneumonia, sepsis, meningitis, and empyema due to Streptococcus pneumoniae is a major cause of morbidity and mortality. (biomedcentral.com)
  • Invasive pneumococcal disease (IPD) is an infection confirmed by the isolation of Streptococcus pneumoniae from a normally sterile site, while non-invasive pneumococcal disease includes sinusitis, mastoiditis, acute otitis media, and community-acquired pneumonia (CAP). (biomedcentral.com)
  • Streptococcus pneumoniae ) OR ( S. pneumoniae ) OR pneumococcal OR pneumococcus) AND (polymorphisms OR polymorphism OR (genetic variant) OR (genetic variants) OR (genetic association study) OR (single nucleotide polymorphism) OR (single nucleotide polymorphisms) OR SNP OR SNPs OR genotype OR genotypes) without language restrictions and with search date cut offs between Jan 1, 1983 and Jul 4, 2018. (biomedcentral.com)
  • Streptococcus pneumoniae is the main causative agent of pneumonia, with a 10 to 25 percent rate of isolation in blood cultures. (louisville.edu)
  • We retrospectively analyzed adult patients with positive blood cultures for Streptococcus pneumoniae and clinical and radiological findings compatible with pneumonia in the period between January 2012 and May 2017. (louisville.edu)
  • BACKGROUND: Pneumonia is commonly caused by Streptococcus pneumoniae (pneumococcus) and associated with subsequent cardiovascular complications and increased mortality. (opinvisindi.is)
  • The vaccine prevents invasive pneumococcal diseases (meningitis, sepsis, bacteremic pneumonia), as well as pneumonia and acute otitis caused by the Streptococcus pneumoniae bacterium (pneumococcus). (petrovax.com)
  • Childhood community-acquired pneumonia is most often attributed to Streptococcus pneumoniae , and the greatest incidence of invasive pneumococcal infection (IPD) is observed in children younger than age 2 [ 4 ]. (biomedcentral.com)
  • and meningitis (infection of the coverings of the brain and spinal cord), as well as non-invasive pneumonia (when pneumococcal disease is confined to the lungs). (merck.com)
  • Invasive pneumococcal disease - bacteremic pneumonia, sepsis, meningitis. (jwejr.net)
  • Pneumonia with empyema and/or bacteraemia, meningitis, and bacteraemia are the commonest manifestations of IPD. (biomedcentral.com)
  • IPD) such as meningitis, bacteremic pneumonia and sepsis, patients with IPD. (bvsalud.org)
  • Invasive diseases are bacteremia/sepsis, bacteremic pneumonia and bacterial meningitis. (srce.hr)
  • Of the 67 patients, 47 had a diagnosis of bacteremia, 11 patients had been diagnosed with a bacteremic pneumonia, and 9 patients with bacterial meningitis. (srce.hr)
  • Pneumococcal disease can cause serious invasive diseases including meningitis, bacteremic pneumonia, hemolytic uremic disease, and non-invasive diseases such as acute otitis media and sinusitis. (trinitymedical.com.hk)
  • A recent study found that patients with macrolide-resistant pneumococcal bacteremia were substantially more likely to have been exposed to macrolide therapy before hospitalization than were patients with macrolide-susceptible pneumococcal bacteremia ( 6 ). (cdc.gov)
  • The estimated annual rate for pneumococcal bacteremia in 1984 was 15-19 per 100,000 population and in 1986-87 was 50 per 100,000 persons greater than or equal to 65 years of age, representing twofold to threefold increases over previously documented rates (5,6). (cdc.gov)
  • 91% of persons aged 19-64 years with bacteremia had underlying medical conditions for which pneumococcal vaccine is recommended (6). (cdc.gov)
  • examples of noninvasive disease include pneumonia without bacteremia, sinusitis, or otitis media. (cdc.gov)
  • Pneumococcal bacteremia is uncommon among U.S. adolescents, particularly serotype 5, with only three such cases identified in the past 10 years by CDC (2). (cdc.gov)
  • Age younger than 65 years, hypoalbuminemia, a need for intensive respiratory or vasopressor support (IRVS), and high serum C-reactive protein (CRP) levels are independent risk factors for the development of bacteremia in patients with pneumococcal community-acquired pneumonia (CAP), according to an article published in BMC Pulmonary Medicine . (infectiousdiseaseadvisor.com)
  • Using logistic regression models, Yasuyoshi Washio of the department of respiratory medicine at Saiseikai Fukuoka General Hospital, Fukuoka, Japan, and colleagues retrospectively analyzed data from 389 patients hospitalized with pneumococcal CAP between April 2007 and August 2015 at Kurashiki Central Hospital, Okayama, Japan, to determine risk factors for pneumococcal bacteremia . (infectiousdiseaseadvisor.com)
  • 20 mg/dL as independent risk factors for the development of pneumococcal bacteremia. (infectiousdiseaseadvisor.com)
  • Washio Y, Ito A, Kumagai S, Ishida T, Yamazaki A. A model for predicting bacteremia in patients with community-acquired pneumococcal pneumonia: a retrospective observational study . (infectiousdiseaseadvisor.com)
  • Prediction of mortality in children with pneumonia-related bacteremia is necessary for providing timely care and treatment. (highwire.org)
  • This study aims to develop and validate a nomogram and compare it with Pediatric Risk of Mortality III (PRISM III), Brighton Pediatric Early Warning Score (Brighton PEWS) and Pediatric Critical Illness Score (PCIS), which are widely used in predicting in-hospital mortality in children with pneumonia-related bacteremia. (highwire.org)
  • This retrospective study collected clinical data of hospitalized children with pneumonia-related bacteremia in Chongqing, China (January 2013-May 2019). (highwire.org)
  • The nomogram was compared with PRISM III, PEWS and PCIS in accuracy and clinical benefits in predicting in-hospital mortality in children with pneumonia-related bacteremia. (highwire.org)
  • In conclusion, a nomogram-illustrated model incorporating TTFP, ALB and LDH for predicting in-hospital mortality in children with pneumonia-related bacteremia at the early stage was established and validated. (highwire.org)
  • There is no predictive model for predicting in-hospital mortality in children with pneumonia-related bacteremia at the early stage. (highwire.org)
  • Laboratory indexes including time to first positivity of blood cultures (TTFP), serum albumin (ALB) and lactate dehydrogenase (LDH) were closely related to in-hospital mortality in children with pneumonia-related bacteremia. (highwire.org)
  • The nomogram including TTFP, ALB and LDH was established for predicting in-hospital mortality in children with pneumonia-related bacteremia. (highwire.org)
  • This nomogram-illustrated model may be a new approach to predicting in-hospital mortality in children with pneumonia-related bacteremia. (highwire.org)
  • Unlike the 13-valent pneumococcal conjugate vaccine (PCV13), PCV15 was licensed for adults before submission for licensure for children. (cdc.gov)
  • Until October 20, 2021, two pneumococcal vaccines (PCV13 and 23-valent pneumococcal polysaccharide vaccine [PPSV23]) were recommended for use in adults, and the recommendations varied by age- and risk-groups. (cdc.gov)
  • and adults with immunocompromising conditions, cochlear implant or CSF leak were recommended to receive a dose of 13-valent pneumococcal polysaccharide vaccine (PCV13) followed by PPSV23 at least 8 weeks later [3]. (cdc.gov)
  • Introduction of PCV13 in children in 2010 reduced the invasive pneumococcal disease (IPD) incidence due to PCV13-types in both adults with CMC and IC aged 19-64 years (ABCs unpublished data). (cdc.gov)
  • Two Phase 3 randomized-controlled trials compared the immunogenicity of PCV15+PPSV23 series with PCV13+PPSV23 series [5, 6] (please refer to GRADE tables for details) among younger adults at increased risk of pneumococcal disease. (cdc.gov)
  • Before 2021, ACIP recommended 23-valent pneumococcal polysaccharide vaccine (PPSV23) alone (up to 2 doses), or both a single dose of 13-valent pneumococcal conjugate vaccine (PCV13) in combination with 1-3 doses of PPSV23 in series (PCV13 followed by PPSV23), for use in U.S. adults depending on age and underlying risk for pneumococcal disease. (cdc.gov)
  • In addition, ACIP recommends use of either a single dose of PCV20 or ≥1 dose of PPSV23 for adults who have started their pneumococcal vaccine series with PCV13 but have not received all recommended PPSV23 doses. (cdc.gov)
  • Because of the concern that unaccompanied children were at increased risk for influenza and pneumococcal pneumonia in this outbreak setting and the clinically important interaction between influenza and pneumococcal infections (3), CDC recommended that all children residing in temporary or standard ORR shelters receive influenza vaccine and PCV13 in addition to routinely recommended vaccines. (cdc.gov)
  • Should PCV20 be recommended as an option for pneumococcal conjugate vaccination according to currently recommended dosing and Currently, either PCV13 or PCV15 can be used for U.S. children. (cdc.gov)
  • Use of PCVs (PCV7, PCV13) significantly decreased the incidence of pneumococcal disease in U.S. children. (cdc.gov)
  • Since August, 2014, the Advisory Committee on Immunization Practices (ACIP) has recommended routine use of 13-valent pneumococcal conjugated vaccine (PCV13, Prevnar) in adults ≥ 65 years, in addition to the traditional 23-valent pneumococcal polysaccharide vaccine (PPSV23, Pneumovax) (1). (pearls4peers.com)
  • The approval of PCV13 was based on a large randomized, double-blind, placebo-controlled trial (CAPITA) that found PCV13 effective in preventing vaccine-type pneumococcal, bacteremic, and nonbacteremic community-acquired pneumonia and vaccine-type invasive pneumococcal disease (2). (pearls4peers.com)
  • So it makes sense to give PCV13 first in our older pneumococcal vaccine-naive patients. (pearls4peers.com)
  • Currently, non-encapsulated H. influenzae , also called non-typeable H. influenzae (NTHi), is responsible for the majority of cases of otitis media, sinusitis, and pneumonia in patients that have already been immunized with the vaccine. (statpearls.com)
  • Historically, encapsulated, type b (Hib) strain accounts for most bacteremic pneumonia and invasive disease, whereas non-encapsulated strains mostly cause otitis media , sinusitis , AECB and pneumonia . (hopkinsguides.com)
  • While healthy adults can suffer from pneumococcal disease, patient populations particularly vulnerable to infection include older adults such as those 65 years of age and older, people with HIV, and those with certain chronic health conditions. (merck.com)
  • If a pneumococcal infection is suspected or considered, Gram stain and culture of appropriate specimens should be obtained, when possible. (medscape.com)
  • Lower respiratory tract infection (LRTI) is a term often used as a synonym for pneumonia but can also be applied to other types of infection including lung abscess and acute bronchitis. (wikipedia.org)
  • Pneumonia is a serious infection of the small bronchioles and alveoli that can involve the pleura. (bionity.com)
  • We describe the rare complication of necrotizing pneumonia and invasive pneumococcal infection in 3 previously healthy pediatric patients . (lookfordiagnosis.com)
  • Controversies exist regarding the prognostic impact of a history of human immunodeficiency virus (HIV) infection on community-acquired pneumonia. (louisville.edu)
  • Additional infection-causing serotypes have been included in the updated 15- and 20-valent pneumococcal conjugate vaccines. (msdmanuals.com)
  • People who are chronically ill or immunocompromised are three times more likely to die from pneumococcal infection than healthy individuals. (trinitymedical.com.hk)
  • INTRODUCTION - Community-acquired pneumonia (CAP) is defined as an acute infection of the pulmonary parenchyma in a patient who has acquired the infection in the community, as distinguished from hospital-acquired (nosocomial) pneumonia. (medilib.ir)
  • Although Pneumococcal Conjugate Vaccines (PCVs) are available and have significantly reduced the rate of invasive pneumococcal diseases, there is still a need for new vaccines with unlimited serotype coverage, long-lasting protection, and lower cost to be developed. (mdpi.com)
  • Current pneumococcal vaccines use the pneumococcal capsular polysaccharides as antigens to generate serotype-specific antibodies, which facilitate serotype-specific clearance of pneumococci through opsonophagocytosis ( 4 ). (cdc.gov)
  • Zurück zum Zitat Africano HF, Serrano-Mayorga CC, Ramirez-Valbuena PC et al (2021) Major adverse cardiovascular events during invasive pneumococcal disease are serotype dependent. (springermedizin.de)
  • The study is limited by the inability to determine pneumococcal serotype or vaccination status and by its small size and retrospective design. (infectiousdiseaseadvisor.com)
  • Serotype 3 strains, which are more heavily encapsulated and tend to form more mucoid colonies than other serotypes, are common causes of invasive pneumococcal disease in adults. (msdmanuals.com)
  • Serotype 19A was the major serotype for all vaccine types in patients with pneumococcal pneumonia and severity of acute inflammatory response was reduced in vaccinated patients. (biomedcentral.com)
  • We determined pneumococcal colonization prevalence and density, and serotype distribution of colonizing isolates. (cdc.gov)
  • If approved, 20vPnC will cover more serotypes responsible for the majority of pneumococcal disease than any other pneumococcal conjugate vaccine currently licensed or currently in late-stage clinical development. (pfizer.com)
  • At least 100 pneumococcal serotypes were documented as of 2020 ( 5 - 7 ). (cdc.gov)
  • During 2018-2019, approximately 60%-75% of all IPD in adults was caused by the 24 pneumococcal serotypes that were included in the formulations of commercially available polysaccharide conjugate vaccine (PCV) or pneumococcal polysaccharide vaccine (PPSV) vaccines (i.e. (cdc.gov)
  • Most cases of IPB's disease are caused by a limited number of pneumococcal serotypes (less than 10). (srce.hr)
  • 90 different pneumococcal serotypes have been identified based on their reaction with type-specific antisera. (msdmanuals.com)
  • We investigated the impact of stepwise implementation of childhood PCV programs on the prevalence of pneumococcal pneumonia, severity of acute inflammation, and associations between breakthrough pneumonia and pneumococcal serotypes in Taiwan. (biomedcentral.com)
  • All of the serotypes, particularly type b, are common etiological agents in lower respiratory tract infections such as pneumonia. (statpearls.com)
  • Outpatient ARIs caused by pneumococcus, such as AOM, sinusitis, and pneumonia, are common causes of outpatient visits and antibiotic prescribing. (cdc.gov)
  • In 2021, two new pneumococcal conjugate vaccines (PCVs), a 15-valent and a 20-valent PCV (PCV15 and PCV20), were licensed for use in U.S. adults aged ≥18 years by the Food and Drug Administration. (cdc.gov)
  • it is now included in the 13-, 15-, and 20-valent pneumococcal conjugate vaccines. (msdmanuals.com)
  • These vaccines have been extensively studied, are currently in human trial phase 1/2, and seem to be the best treatment choice for pneumococcal diseases, especially for developing countries. (mdpi.com)
  • Canadian guidelines for the initial management of community-acquired pneumonia: an evidence-based update by the Canadian Infectious Diseases Society and the Canadian Thoracic Society. (jamanetwork.com)
  • Background: Chronic conditions increase the risk of invasive pneumococcal diseases (IPD). (bvsalud.org)
  • The article presents a comparative analysis of basic provisions of the 2019 American Thoracic Society/Infectious Diseases Society of America (ATS/IDSA) guideline and the 2018 Russian Respiratory Society/Interregional Association for Clinical Microbiology and Antimicrobial Chemotherapy (RRS/IACMAC) draft guideline which consider diagnosis and antimicrobial therapy for community-acquired pneumonia in adults. (omnidoctor.ru)
  • There are a number of acute and chronic infections that can affect the lower respiratory tract, the focus of this paper is to look at the two most common infections, Bronchitis and Pneumonia, as identified by the Therapeutic guidelines. (bionity.com)
  • Older adults, even those without other disease, tend to have a poor prognosis with pneumococcal infections. (msdmanuals.com)
  • Damage to the respiratory epithelium by chronic bronchitis or common respiratory viral infections, notably influenza, may predispose to pneumococcal invasion. (msdmanuals.com)
  • Pneumococcal conjugate vaccine (PCV) reduces both invasive pneumococcal disease (IPD) and other pneumococcal infections worldwide. (biomedcentral.com)
  • Pneumococcus can colonize the upper respiratory tract, most commonly in young children, and is transmitted to others through contact with respiratory droplets from a person with pneumococcal colonization in the upper respiratory tract ( 1 ). (cdc.gov)
  • In adults, pneumococcal pneumonia is the most common type of pneumococcal disease, and pneumococcus is the most common bacterial cause of pneumonia that results in hospitalization ( 3 ). (cdc.gov)
  • In no sub-group of assessed cases did pneumococcal colonization density exceed the median for controls, including cases with no prior antibiotics (63.9x103 copies/mL), with consolidation on chest x-ray (76.5x103 copies/mL) or with pneumococcus detected in whole blood by PCR (9.3x103 copies/mL). (cdc.gov)
  • Use of 13-valent pneumococcal conjuage vaccine and 23-valent penumococcal polysaccharide vaccine among adults aged ≥65 years: recommendations of the Advisory Committe on Immunization Practices (ACIP). (pearls4peers.com)
  • The ATS Board of Directors, Guidelines for the initial management of adults with community-acquired pneumonia: diagnosis, assessment of severity, and initial antimicrobial therapy. (jamanetwork.com)
  • Dot-ELISA proved to be a practical alternative technique for the diagnosis of pneumococcal pneumonia. (scielo.br)
  • Guidelines for the initial management of adults with community-acquired pneumonia: diagnosis, assessment of severity, and initial antimicrobial therapy. (omnidoctor.ru)
  • See "Community-acquired pneumonia in children: Clinical features and diagnosis" . (medilib.ir)
  • Should PCV20 without PPSV23 be recommended as an option for pneumococcal vaccination for U.S. children aged 2-18 years with underlying medical conditions that increase the risk of pneumococcal disease? (cdc.gov)
  • The present data contribute to pneumococcal vaccination public health policies for vulnerable patients, mainly those with comorbidity and the elderly. (bvsalud.org)
  • The authors suggest that this may be because of poorer pneumococcal vaccination rates among younger patients in Japan. (infectiousdiseaseadvisor.com)
  • Systematic childhood pneumococcal vaccination reduced the prevalence of community-acquired pneumococcal pneumonia, especially in 2-5 year group. (biomedcentral.com)
  • Universal vaccination with PCV7 also resulted in a 77% reduction in pneumococcal disease in children aged 1-5 and a 39% reduction in hospitalization of children age under age 2 [ 3 ]. (biomedcentral.com)
  • What's the latest on vaccination of adults 65 years old or over with conjugated pneumococcal vaccine? (pearls4peers.com)
  • Cite this: Pneumococcal Pneumonia Outcomes Worse Than Legionnaires Disease - Medscape - Mar 30, 2022. (medscape.com)
  • In a case-control study, outcomes for 58 human immunodeficiency virus (HIV)-positive patients with community-acquired pneumonia ( CAP) were compared with outcomes for 174 HIV-negative patients with CAP. (omeka.net)
  • Rosón BCarratalà JDorca JCasanova AManresa FGudiol F Etiology, reasons for hospitalization, risk classes and outcomes of patients with community-acquired pneumonia hospitalized on the basis of conventional admission criteria. (jamanetwork.com)
  • Prognosis and outcomes of patients with community-acquired pneumonia: a meta-analysis. (jamanetwork.com)
  • Causes of death for patients with community-acquired pneumonia: results from the Pneumonia Patient Outcomes Research Team Cohort Study. (jamanetwork.com)
  • Antibiotic combination therapy has been reported to improve outcomes for patients with bacteremic pneumococcal CAP. (infectiousdiseaseadvisor.com)
  • Zurück zum Zitat Wagenvoort GH, Sanders EA, de Melker HE et al (2017) Long-term mortality after IPD and bacteremic versus non-bacteremic pneumococcal pneumonia. (springermedizin.de)
  • Pneumococcal disease is the primary cause of childhood morbidity and mortality worldwide, resulting in 0.7 to 1.0 million deaths each year in children younger than age 5 years [ 3 ]. (biomedcentral.com)
  • British Thoracic Society Standards of Care Committee, BTS Guidelines for the Management of Community Acquired Pneumonia in Adults. (jamanetwork.com)
  • Time to clinical stability in patients hospitalized with community-acquired pneumonia: implications for practice guidelines. (jamanetwork.com)
  • This report describes the public health impact of influenza, pneumococcal disease, hepatitis B, and measles on U.S. adults. (cdc.gov)
  • From January through March 1990, a major influenza epidemic was associated with a high proportion of pneumonia and influenza (P&I) deaths. (cdc.gov)
  • The year 2000 health objectives include reduction of epidemic-related P&I deaths and provision of influenza and pneumococcal vaccines to at least 60% of high-risk populations. (cdc.gov)
  • The fourth patient, without pneumonia, had PCR-confirmed influenza A(H1N1)pdm09. (cdc.gov)
  • Zurück zum Zitat von Baum H, Schweiger B, Welte T et al (2011) How deadly is seasonal influenza-associated pneumonia? (springermedizin.de)
  • Cambios en la presentación clínica de la influenza A H1N1pdm09 después de la pandemia. (bvsalud.org)
  • Although considerable controversy exists about the clinical impact of pneumococcal drug resistance ( 2 ), the prevalence of single-drug and multidrug-resistant pneumococci has increased in the last 2 decades ( 3 , 4 ). (cdc.gov)
  • BACKGROUND: Pneumococcal colonization prevalence and colonization density, which has been associated with invasive disease, can offer insight into local pneumococcal ecology and help inform vaccine policy discussions. (cdc.gov)
  • The ACIP Pneumococcal Vaccines Work Group reviewed available data to inform the use of PCV15 in adults and identify policy options that maximize pneumococcal disease prevention among adults, reduce disparity, and simplify recommendations to improve vaccine uptake. (cdc.gov)
  • In a retrospective case companion study published in the American Journal of the Medical Sciences , the researchers reviewed data from 51 adults with LD and 55 with bacteremic S. pneumoniae pneumonia (SP) who were hospitalized at a single center between 2013 and 2018. (medscape.com)
  • 4] H influenzae and M catarrhalis are of increasing importance in both community acquired pneumonia (CAP) and acute exacerbation of chronic bronchitis (AECB) while the importance of S pneumoniae is declining. (bionity.com)
  • Bacteremic pneumococcal pneumonia is among the most serious forms of pneumococcal disease, and incidence rises steeply with advancing age ( 1 ). (cdc.gov)
  • Community-acquired pneumonia (CAP) is a relatively frequent infectious disease with an incidence that ranges from 3-6 cases per 1,000 inhabitants per year 1 . (ersjournals.com)
  • Pneumococcal resistance to macrolides is a problem because macrolides are among the most common oral drugs used to treat patients with community-acquired pneumonia ( 5 ). (cdc.gov)
  • Since most initial therapy of community-acquired pneumonia is empiric, estimating the probability of macrolide-resistant pneumococcal disease is necessary to select appropriate therapy. (cdc.gov)
  • Indeed, current treatment guidelines recommend not prescribing macrolide therapy alone for patients with community-acquired pneumonia if they report exposure to macrolides within the 3 months preceding the onset of illness ( 7 ). (cdc.gov)
  • Community-acquired pneumonia (CAP) in the elderly has increased as a consequence of an overall increase of the elderly population. (ersjournals.com)
  • The results of this study may aid in the management of empiric antibiotic treatment in elderly patients with community-acquired pneumonia and the patients who have a greater probability of bad evolution may be identified based on the risk factors. (ersjournals.com)
  • The German Competence Network for Community-Acquired Pneumonia. (springermedizin.de)
  • Managing the nonsurgical candidate with an empyema related to community-acquired lobar pneumonia. (lookfordiagnosis.com)
  • Bartlett JGMundy LM Community-acquired pneumonia. (jamanetwork.com)
  • Marrie TJDurant HYates L Community-acquired pneumonia requiring hospitalization: 5-year prospective study. (jamanetwork.com)
  • Community-acquired pneumonia: impact of immune status. (jamanetwork.com)
  • A prediction rule to identify low-risk patients with community-acquired pneumonia. (jamanetwork.com)
  • Ortqvist AKalin MLejdeborn LLundberg B Diagnostic fiberoptic bronchoscopy and protected brush culture in patients with community-acquired pneumonia. (jamanetwork.com)
  • We provide a systemic overview of genetic variants associated with susceptibility, phenotype and outcome of community acquired pneumococcal pneumonia (CAP) and invasive pneumococcal disease (IPD). (biomedcentral.com)
  • Sequential IV/PO moxifloxacin communication of patients with severe community-acquired pneumonia order 80mg tadapox amex erectile dysfunction icd 9 code. (mein-schoenefeld.info)
  • In total, 983 children diagnosed with community-acquired pneumococcal pneumonia were enrolled between January 2010 and December 2015. (biomedcentral.com)
  • Sinopalnikov A.I. United States (ATS/IDSA, 2019) and Russian (RRS/IACMAC, 2019) guidelines on community-acquired pneumonia management in adults. (omnidoctor.ru)
  • community-acquired pneumonia in adults, clinical recommendations. (omnidoctor.ru)
  • 2. Mandell LA, Niederman M, The Canadian Community-Acquired Pneumonia Consensus Conference Group. (omnidoctor.ru)
  • Antimicrobial treatment of community-acquired pneumonia in adults: A conference report. (omnidoctor.ru)
  • See "Community-acquired pneumonia in children: Outpatient treatment" . (medilib.ir)
  • Indications - The decision to hospitalize a child with community-acquired pneumonia (CAP) is individualized based upon age, underlying medical problems, and clinical factors including severity of illness ( table 1 ) [ 1-3 ]. (medilib.ir)
  • TMP/SMX may reduce the risk of community-acquired pneumonia . (hopkinsguides.com)
  • Does sputum culture affect the management and/or outcome of community-acquired pneumonia? (who.int)
  • ABSTRACT This prospective study was conducted in 6 hospitals in Edmonton, Canada to determine the factors associated with obtaining sputum for culture and the effect of sputum culture on the management of patients with community-acquired pneumonia (CAP). (who.int)
  • A 15-valent pneumococcal conjugate vaccine (PCV15, Merck) was licensed for adults in July 2021. (cdc.gov)
  • On June 8, 2021, a 20-valent pneumococcal conjugate vaccine (PCV20, Pfizer) was licensed for use in adults aged ≥18 years. (cdc.gov)
  • Zurück zum Zitat Amin-Chowdhury Z, Aiano F, Mensah A et al (2021) Impact of the Coronavirus disease 2019 (COVID-19) pandemic on invasive pneumococcal disease and risk of pneumococcal coinfection with severe acute respiratory syndrome Coronavirus 2 (SARS-coV-2): prospective national cohort study, england. (springermedizin.de)
  • We conducted a population-based case-control study to identify clinical and demographic factors independently associated with macrolide-resistant bacteremic pneumococcal pneumonia in adults. (cdc.gov)
  • The aim of our work was to analyze and compare the clinical presentation, radiological findings and progression of pneumococcal pneumonia in patients infected with and not infected with HIV. (louisville.edu)
  • A total of 442 pleural fluid effusion samples (PFES) from children with clinical and laboratory diagnoses of acute bacterial pneumonia, plus 38 control PFES from tuberculosis patients and 20 negative control serum samples from healthy children were evaluated by Dot-ELISA. (scielo.br)
  • Indications for intensive care - The decision to treat a child with pneumonia in an intensive care setting is individualized, based upon clinical, laboratory, and radiologic findings. (medilib.ir)
  • This report compiles and summarizes all published recommendations from CDC's Advisory Committee on Immunization Practices (ACIP) for use of pneumococcal vaccines in adults aged ≥19 years in the United States. (cdc.gov)
  • Pneumococcal septicemia in children with sickle cell anemia: changing trend of survival. (cmcedmasters.com)
  • On July 10, 2014, CDC was informed by the California Department of Public Health and Office of Refugee Resettlement (ORR) about four unaccompanied male children aged 14-16 years with respiratory illnesses at Naval Base Ventura County, three of whom were hospitalized with pneumonia. (cdc.gov)
  • METHODS: The Pneumonia Etiology Research for Child Health Project (PERCH), a multi-country case-control study, evaluated the etiology of hospitalized cases of severe and very severe pneumonia among children aged 1-59 months. (cdc.gov)
  • RESULTS: We enrolled 224 severe/very severe pneumonia cases and 659 community controls in Thailand. (cdc.gov)
  • However, colonization density was not higher among children with severe pneumonia compared to controls. (cdc.gov)
  • A quarter to a third of pneumonia and 27.3% of severe pneumonia in children are caused by bacteria. (highwire.org)
  • Certain persons with pneumococcal colonization might develop invasive pneumococcal disease (IPD) ( 2 ). (cdc.gov)
  • HIV appears to be a risk factor for developing invasive disease due to H. influenzae type b, especially bacteremic pneumonia. (hopkinsguides.com)
  • Adults with certain underlying conditions are at increased risk of pneumococcal disease[1, 2]. (cdc.gov)
  • According to US healthcare claims data, the risk of hospitalized pneumococcal pneumonia among adults aged 18-64 years with CMC was 4-5 times, and among those with IC was 11-18 times higher than adults without these conditions [4]. (cdc.gov)
  • Risk of disease remains high in children with underlying conditions that increase the risk of pneumococcal disease. (cdc.gov)
  • Studies have identified several host genetics factors influencing risk of pneumococcal disease, but many result in non-reproducible findings due to methodological limitations. (biomedcentral.com)
  • Dot-enzyme-linked immunosorbent assay (Dot-ELISA) for detection of pneumococcal polysaccharide antigens in pleural fluid effusion samples. (scielo.br)
  • Comparison with bacterial culture, counterimmunoelectrophoresis and latex agglutination Dot-enzyme-linked immunosorbent assay (Dot-ELISA) for detection of pneumococcal polysaccharide antigens in pleural fluid effusion samples. (scielo.br)