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  • Neuroblastoma
  • A wide body of literature provides evidence for effective treatment of different tumor cells using HDAC inhibitors (HDACi) in vitro and in vivo , such as leukemia ( 8 ), lymphoma ( 9 ), lung cancer ( 10 , 11 ), retinoblastoma ( 12 ), and neuroblastoma ( 13 , 14 ). (aacrjournals.org)
  • Wilms
  • Biopsies were obtained from patients at The Children's Hospital of Philadelphia or other hospitals, as well as from the Cooperative Human Tissue Network and National Wilms' Tumor Study Group tumor banks. (aacrjournals.org)
  • suppressor genes
  • AT/RT has been linked to somatic and germline mutations of SMARCB1 and, less commonly, SMARCA4 , both of which are tumor suppressor genes. (cancer.gov)
  • Here, we present an overview of AN in the SVZ-OB and olfactory epithelium (OE) in mice and humans followed by a comprehensive update of the distinct roles played by cell cycle proteins including major tumors suppressor genes in various steps during neurogenesis. (frontiersin.org)
  • Cancer
  • Each unique tumor model and its biological characteristic data is available to all academically qualified petitioners-opening the door for breakthroughs in childhood cancer research. (alexslemonade.org)
  • Other lesions may mimic squamous cell cancer and invade the larynx, and these include thyroid cancer as well as chondroid tumors from the adjacent thyroid cartilage. (ucsd.edu)
  • Healthy tissues surrounding the pediatric cancer are spared from excess radiation, meaning physicians can deliver more potent doses of radiation directly to the child's tumor. (floridaproton.org)
  • gastrointestinal
  • The present case was clinically and radiologically misdiagnosed as a pancreatic tumor/gastrointestinal stromal tumor. (kjim.org)
  • The possibility of an exophytic pancreatic mass or exophytic gastrointestinal stromal tumor (GIST) from the posterolateral wall of the stomach was proposed ( Fig. 1 ). (kjim.org)
  • glioblastoma
  • Attenuation of Tumor Suppressive Function of FBXO16 Ubiquitin Ligase Activates Wnt Signaling In Glioblastoma. (abcam.com)
  • immunohistochemical
  • Other histologic and immunohistochemical features, such as the degree of apparent cellular transformation along identifiable cell lineages (ependymal, glial, etc.), can be used to separate these tumors to some degree. (cancer.gov)
  • 1 , 3 - 6 AT/RTs can now be distinguished from PNET and other tumors by using specific immunohistochemical markers and by detection of deletions and/or mutations involving the hSNF5/INI1 tumor-suppressor gene in chromosome band 22q11.2. (ajnr.org)
  • subtypes
  • Since fine-needle aspiration biopsy is insufficient to determine subtypes of malignant tumors, Tru-cut needle biopsy is the diagnostic tool of choice in most cases. (chestwall.org)