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Acyl Carrier ProteinCarrier ProteinsFatty Acid Synthase, Type II3-Oxoacyl-(Acyl-Carrier-Protein) SynthasePantetheineAcyl-Carrier Protein S-MalonyltransferaseEnoyl-(Acyl-Carrier-Protein) Reductase (NADH)Carrier State3-Oxoacyl-(Acyl-Carrier-Protein) ReductaseEscherichia coliTransferases (Other Substituted Phosphate Groups)TriclosanAcyltransferasesMolecular Sequence DataPolyketide SynthasesCarbon-Sulfur LigasesAmino Acid SequenceFatty Acid SynthasesDrug CarriersReduced Folate Carrier ProteinFatty AcidsCoenzyme AThiolester HydrolasesBacterial ProteinsMembrane Transport ProteinsEnoyl-(Acyl-Carrier Protein) Reductase (NADPH, B-Specific)Heterozygote DetectionKineticsLigasesMitochondrial ADP, ATP TranslocasesCloning, MolecularAcylationCarbon-Nitrogen LigasesSubstrate SpecificitySequence Homology, Amino AcidAcetyl-CoA C-AcetyltransferasePeptide SynthasesBase SequenceCeruleninPantothenic AcidHeterozygoteMalonyl Coenzyme AModels, MolecularBiotinAcetyl-CoA CarboxylaseMalonatesGalactosidesMutationEscherichia coli ProteinsStreptomycesBiological TransportProtein ConformationVaccines, ConjugateApoproteinsUbiquitin-Conjugating EnzymesCrystallography, X-RayHaptensProton-Coupled Folate TransporterRecombinant ProteinsProtein BindingAcetyl Coenzyme ACoriandrumBinding SitesProtein Structure, TertiaryHemocyaninMultienzyme ComplexesMitochondriaMitochondrial ProteinsDicarboxylic Acid TransportersSterolsOxidoreductasesFatty Acid Synthesis InhibitorsThioctic AcidPlant ProteinsGenetic Complementation TestSymportersPhosphate-Binding ProteinsMycolic AcidsSaccharopolysporaPlantsMolecular WeightLipid AElectrophoresis, Polyacrylamide GelHydro-LyasesSequence AlignmentDansyl CompoundsCatalysisDNA PrimersGenes, BacterialCarboxyl and Carbamoyl TransferasesHydrogen-Ion ConcentrationMultigene FamilyGlycosidesGlycoconjugatesSulfhydryl CompoundsBiological Transport, ActiveMixed Function OxygenasesAnthraquinonesMolecular StructurePeptide Biosynthesis, Nucleic Acid-Independent
AcylGeneSecretoryGenesTransporterEnzymeInteractionsMembraneKinaseProteomicsCellsImmunoprecipitationMetabolismReceptorsInteractionHepatocellularMolecularTargetsContaining the recombinantLipidVirologyTarget proteinHumansAccumulationMass spectrometryUpstreamTransportersHumanNanocarriersStructuralStability
Acyl5
  • The systematic name is dodecanoyl-[acyl-carrier-protein] hydrolase. (wikipedia.org)
  • Other names in common use include lauryl-acyl-carrier-protein hydrolase, dodecanoyl-acyl-carrier-protein hydrolase, dodecyl-acyl-carrier protein hydrolase, and dodecanoyl-[acyl-carrier protein] hydrolase. (wikipedia.org)
  • The acyl carrier protein of lipid synthesis donates lipoic acid to the pyruvate dehydrogenase complex in Escherichia coli and mitochondria. (enzyme-database.org)
  • The mitochondrial acyl carrier protein (ACPM/NDUFAB1) is a central element of the mitochondrial fatty acid synthesis type II machinery. (mitophysiology.org)
  • We show that the presence of a long acyl chain bound to the phosphopantetheine cofactor is important for docking ACPMs to protein complexes and we propose that association of ACPMs and LYRMs is universally based on a new protein-protein interaction motif. (mitophysiology.org)
Gene10
  • This gene product belongs to the SCAMP family of proteins, which are secretory carrier membrane proteins. (nih.gov)
  • It is associated with a mutation of the ABCB4 gene which codes for protein MDR3, a biliary carrier. (nih.gov)
  • Morris, T.W., Reed, K.E. and Cronan, J.E., Jr. Identification of the gene encoding lipoate-protein ligase A of Escherichia coli . (enzyme-database.org)
  • This gene encodes a member of the solute carrier family 6 protein family which transports neutral amino acids. (nih.gov)
  • Description of the protein which includes the UniProt Function and the NCBI Gene Summary. (nih.gov)
  • Total count of NCBI Gene Reference Into Function hits for target listed in parenthesis, and summary table with links to publications per PMID with the specific text in article that includes the reported target. (nih.gov)
  • The GAB2 gene, encoding the GRB-associated binding protein 2, has been studied for its additive effect on the risk of developing late-onset Alzheimer's disease in conjunction with carriers of ApoE4 alleles. (snpedia.com)
  • The human solute carrier gene SLC35B4 encodes a bifunctional nucleotide sugar transporter with specificity for UDP-xylose and UDP-N-acetylglucosamine. (nih.gov)
  • This process allows a variety of important applications, including the study of gene regulation, the analysis of the expression of proteins within eukarotic cells such as those of mammals, the production of transgenic organisms , and the methods of gene therapy. (newworldencyclopedia.org)
  • 2) Please refer to table 1 in Has's manuscript (reference 1) that elaborates the cutaneous features, associated features, and affected gene/protein for localized PSS, generalized noninflammatory PSS, and generalized inflammatory PSS. (aad.org)
Secretory2
  • COPI is a key mediator of protein trafficking within the secretory pathway. (univ-lille.fr)
  • Loss of GORAB causes impairment of COPI-mediated retrieval of trans-Golgi enzymes, resulting in a deficit in glycosylation of secretory cargo proteins. (univ-lille.fr)
Genes1
  • Subsequent molecular and physiological studies in human mutation carriers and animal models have allowed us to unravel novel functions of the identified genes, to delineate their cognate pathways and to discover new targets for pharmaceutical intervention. (yale.edu)
Transporter1
Enzyme4
  • The enzyme attaches lipoic acid to the lipoyl domains of certain key enzymes involved in oxidative metabolism, including pyruvate dehydrogenase (E 2 domain), 2-oxoglutarate dehydrogenase (E 2 domain), the branched-chain 2-oxoacid dehydrogenases and the glycine cleavage system (H protein) [6]. (enzyme-database.org)
  • Conclusion: Our data suggest that UBE2Q1 as an E2 enzyme of ubiquitination system can interact with B4GALT1 and P53, and may contribute to the accumulation of misfolded important proteins and colorectal tumor development. (eurekaselect.com)
  • We also use biochemical methods (protein expression/purification and mass spectrometry) to elucidate enzyme processes in microorganisms. (upr.edu)
  • Nasu, S., Wicks, F.D. and Gholson, R.K. L -Aspartate oxidase, a newly discovered enzyme of Escherichia coli , is the B protein of quinolinate synthetase. (enzyme-database.org)
Interactions3
  • Differential interactions of cerebellin precursor protein (Cbln) subtypes and neurexin variants for synapse formation of cortical neurons. (mblbio.com)
  • Objective: The present study aimed to evaluate the molecular analysis of possible interactions between UBE2Q1 with B4GALT1 and P53 proteins. (eurekaselect.com)
  • GORAB forms stable domains at the trans-Golgi that, via interactions with the COPI-binding protein Scyl1, promote COPI recruitment to these domains. (univ-lille.fr)
Membrane3
  • ER membrane protein complex is required for the insertions of late-synthesized transmembrane helices of Rh1 in Drosophila photoreceptors. (mblbio.com)
  • As a basement membrane protein, COL4A1 is commonly expressed in many tissues and cell types. (cusabio.com)
  • COPI is recruited to the membrane primarily through binding to Arf GTPases, upon which it undergoes assembly to form coated transport intermediates responsible for trafficking numerous proteins, including Golgi-resident enzymes. (univ-lille.fr)
Kinase1
  • Perilipin 1 binds to aquaporin 7 in human adipocytes and controls its mobility via protein kinase A mediated phosphorylation. (lu.se)
Proteomics2
  • A chemical proteomics approach to identify c-di-GMP binding proteins in Pseudomonas aeruginosa. (helmholtz-hzi.de)
  • In this study, we have established a chemical proteomics approach to identify c-di-GMP interacting proteins in the opportunistic pathogen Pseudomonas aeruginosa. (helmholtz-hzi.de)
Cells4
  • When targeting cancer cells, both animal and plant proteins may be used in a formulation process to create self-assembled viruses and platforms that can successfully eradicate metastatic cancer cells. (benthamscience.com)
  • The direction of auxin flow between cells is closely related to the polar localization of PIN proteins in cells. (chinbullbotany.com)
  • Recombinant Human IL17C Protein is produced by CHO Cells expression system. (creativebiomart.net)
  • Pentraxins3 (PTX3) is an acute-phase protein of the pentraxin family that is synthetized and stored in a variety of cells. (bvsalud.org)
Immunoprecipitation1
  • Using the immunoprecipitation (IP) product of the over-expressed protein on the silver staining gel, we observed the potential interacting partners of UBE2Q1. (eurekaselect.com)
Metabolism1
  • Alters lipid metabolism by interacting with hepatocellular proteins involved in lipid accumulation and storage (PubMed:14602201). (proteopedia.org)
Receptors2
  • The immunosuppressant FTY720 down-regulates sphingosine 1-phosphate G-protein-coupled receptors. (mblbio.com)
  • 7. Offermanns S. Activation of platelet function through G protein-coupled receptors. (sciendo.com)
Interaction2
  • Protein- Protein interaction (PPI) analysis also depicted a high affinity of the UBC domain of UBE2Q1 to the B4GALT1 and P53 (tetramerization and DNA binding domains). (eurekaselect.com)
  • Participates in the viral particle production as a result of its interaction with the non-structural protein 5A (By similarity). (proteopedia.org)
Hepatocellular1
  • Kumar, V. Ganoderic acid loaded nano-lipidic carriers improvise treatment of hepatocellular carcinoma. (benthamscience.com)
Molecular4
  • The Molecular Operating Environment (MOE) software was also used to perform the molecular docking of the UBC domain of UBE2Q1 (2QGX) with B4GALT1 (2AGD), and P53 (tetramerization (1AIE) and DNA binding domains (1GZH)) proteins. (eurekaselect.com)
  • Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. (novusbio.com)
  • C2orf18, termed ANT2-binding protein (ANT2BP), might serve as a candidate molecular target for pancreatic cancer therapy. (nih.gov)
  • Under SDS-PAGE condition, this recombinant COL4A1 protein migrated to the band of about 40 kDa molecular weight. (cusabio.com)
Targets1
  • The PIN protein contains a central hydrophilic loop (HL) and two separated hydrophobic regions, and the multiple phosphorylation sites on HL are the targets of protein kinases. (chinbullbotany.com)
Containing the recombinant1
  • The expression of recombinant human COL4A1 protein includes the construction of the expression vector containing the recombinant DNA and the transformation of the expression vector into the E.coli, which provides a variety of macromolecules and components required for transcription and translation. (cusabio.com)
Lipid1
  • This review highlights the different formulations underlying the encapsulation of FSVs in biopolymer (polysaccharide and protein) and lipid-based micro or nanocarriers for potential applications in food and pharmaceutical industries. (afpm.org.my)
Virology1
  • The work of Plant Virology group is focused on the identification of new viruses in agriculturally relevant plant species, characterization of plant virus genomes and their encoded proteins. (lu.lv)
Target protein2
  • Binding to and carrying a protein between two different cellular components by moving along with the target protein. (ntu.edu.sg)
  • Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request. (cusabio.com)
Humans1
  • The characterization of this protein in vivo has shown that it widely expressed in different tissues and circulates in the blood, its levels rise after food intake in humans and stimulates insulin secretion and sensitivity and inhibits platelet aggregation. (yale.edu)
Accumulation1
  • BACKGROUND: Bacterial infection causes accumulation of neutrophils that release antimicrobial proteins including heparin-binding protein (HBP). (lu.se)
Mass spectrometry1
Upstream1
  • Nascent Transcriptomics Reveal Cellular Prolytic Factors Upregulated Upstream of the Latent-to-Lytic Switch Protein of Epstein-Barr Virus. (ufl.edu)
Transporters1
  • The polar transport of auxin mainly depends on three transporters: AUX/LAX, PIN and ABCB protein families. (chinbullbotany.com)
Human3
  • Unless otherwise stated all data on this page refer to the human proteins. (guidetopharmacology.org)
  • The recombinant DNA was formed by fusing the N-terminal GST tag sequence to the designated sequence encoding the 30-167aa of the human COL4A1 protein. (cusabio.com)
  • The encoded protein is upregulated in human steatosis (NASH). (yale.edu)
Nanocarriers3
  • Results: The advancement in non-viral to viral-based protein-based nanocarriers for treating cancer has earned further recognition in this respect. (benthamscience.com)
  • Many scientific breakthroughs have relied on protein-based nanocarriers, and proteins are essential organic macromolecules for life. (benthamscience.com)
  • It allows targeted delivery of passive or active tumors using non-viral-based protein-based nanocarriers to viral-based protein nanocarriers. (benthamscience.com)
Structural1
Stability3
  • The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. (cusabio.com)
  • In particular, the function of these carrier systems in terms of encapsulation efficiency, stability, bioavailability, and bio-accessibility is critically discussed. (afpm.org.my)
  • Adding a carrier protein enhances protein stability, increases shelf-life, and allows the recombinant protein to be stored at a more dilute concentration. (bio-techne.com)