• Pluronic P123(PEG-PPG-PEG) symmetric triblock copolymer constitutes of poly(ethylene oxide)(PEO) and poly (propylene oxide) (PPO). (wikipedia.org)
  • Triblock copolymers based on poly(ethylene glycol)-poly(propylene glycol)-poly(ethylene glycol) are known generically as poloxamer, and similar materials are manufactured by other companies. (wikipedia.org)
  • 3. A solid PVP-iodide monionic detergent product as defined in claim 2 wherein the poloxamer is one in which the molecular weight of (C 3 H 6 O) y is in the range of about 1500 to 5000 and the groups (C 2 H 4 0) x+x' constitute 70 to 90% of the total weight of said poloxamer. (google.com.au)
  • For the generic term poloxamer , these copolymers are commonly named with the letter P (for poloxamer) followed by three digits: the first two digits multiplied by 100 give the approximate molecular mass of the polyoxypropylene core, and the last digit multiplied by 10 gives the percentage polyoxyethylene content (e.g. (wikipedia.org)
  • P407 = poloxamer with a polyoxypropylene molecular mass of 4000 g/mol and a 70% polyoxyethylene content). (wikipedia.org)
  • Moghimi SM, Hunter AC, Dadswell CM, Savay S, Alving CR, Szebeni J. Causative factors behind poloxamer 188 (Pluronic F68, Flocor™)-induced complement activation in human sera: a protective role against poloxamer-mediated complement activation by elevated serum lipoprotein levels. (springer.com)
  • The safety and efficacy of a new generation of metallic stents covered with a paclitaxel-incorporated membrane using a Pluronic® mixture (MSCPM-II) were compared prospectively with those of covered metal stents (CMSs) in patients with malignant biliary obstructions. (elsevier.com)
  • Hypothesis: The antisense phosphorodiamidate morpholino oligomer (PMO), AVI-4126, has been effective in reducing neointimal formation in animal models following delivery by pluronic gels, local delivery catheters and coated stents. (elsevier.com)
  • Brinzolamide-loaded nanoparticles prepared using PLGA with Pluronic acid F68 in the aqueous phase and 1 % Brij 97 in the organic phase showed the smallest particle size value (441.80 ± 72.97 nm). (fue.edu.eg)
  • Brinzolamide-loaded nanoparticles prepared using PLGA with Pluronic acid F68 in aqueous phase and 2 % polysorbate 80 in organic phase had the largest encapsulation efficiency and drug loading values (47.86 ± 0.97 % and 38.76 %, respectively). (fue.edu.eg)
  • Researchers concluded that use of poloxamer gels holds much promise for prolonged delivery of clotrimazole in nasal sinuses, potentially reducing anesthetic time as well as accomplishing fungal organism eradication after a single course of treatment. (agevital.com)
  • Tween 80 and Poloxamer 188. (otago.ac.nz)
  • Optimum concentrations of Tween 80 and Poloxamer 188 had been determined at 15% w/w (of phytantriol), where the cubosomes formed Im3m and Pn3m internal structures, respectively. (otago.ac.nz)
  • This indicates the significance of ApoE in the plasma which initially binds to the cubosomes surface decorated with Tween 80 and Poloxamer 188, followed by the interaction with LDL-receptor and internalisation into the brain endothelial cells. (otago.ac.nz)
  • Topical compounds in PLO are composed of the active drug(s) suspended in a vehicle consisting of water and two plant derivatives, pluronic acid and lecithin. (enclarapharmacia.com)
  • Six compounds were evaluated including commercially available 1% clotrimazole cream, and 1% clotrimazole in varying concentrations of hydroxypropyl methylcellulose, carboxymethylcellulose, and poloxamer gel. (agevital.com)