• It is indicated for the control and treatment of respiratory infections associated with tilmicosin-susceptible micro-organisms such as Mycoplasma spp. (maizer.fr)
  • Treatment of respiratory infections caused by sensitive strains of Actinobacillus pleuropneumoniae, Mycoplasma hyopneumoniae , and Pasteurella multocida. (kmvetpharm.com.my)
  • Monitoring Mycoplasma gallisepticum and Mycoplasma synoviae infection in breeder chickens after treatment with enrofloxacin. (ncats.io)
  • Studies show that co-infections with Porcine reproductive and respiratory syndrome virus (PRRSV), swine influenza virus (SIV), porcine parvovirus (PPV), Mycoplasma hyopneumoniae, Actinobacillus pleuropneumoniae, Haemophilus parasuis and Streptococcus suis are commonly involved in PCVD. (msd-animal-health.ie)
  • The Ceva Lung Program offers the methodology and guidelines on how to correctly evaluate the presence, incidence, circulation patterns and impact of Mycoplasma hyopneumoniae , Actinobacillus pleuropneumoniae and Aujesky's disease virus infections using serological investigation and adapted lung scoring of slaughter pigs. (ceva.vn)
  • Generally the mycoplasma infection alone is relatively mild and pulls down growth rate and feed conversion efficiency, but it is the secondary bacterial infections that exacerbate the disease and causes acute bronchopneumonia and even death. (octagon-services.co.uk)
  • Actinobacillus pleuropneumoniae (previously Haemophilus pleuropneumoniae), is a Gram-negative, facultative anaerobic, respiratory pathogen found in pigs. (wikipedia.org)
  • The typical presentation of A. pleuropneumoniae in pigs is the characteristic demarcated lesions in the middle, cranial, and caudal lobes of the lungs. (wikipedia.org)
  • A quarter of rearing pigs on another unit died with Typhimurium infections. (thepigsite.com)
  • Results indicated that a Group B salmonella infection was persisting on the unit rather than being brought in with the pigs. (thepigsite.com)
  • The objectives of this study were to elucidate at which age tonsillar colonisation by Actinobacillus pleuropneumoniae occurs in pigs and relate this occurrence to the presence of colostral antibodies to A. pleuropneumoniae. (dtu.dk)
  • The infection patterns were studied in an isolated cohort of pigs, which consisted of the offspring from five sows originating from a conventional pig herd. (dtu.dk)
  • The pigs were examined repeatedly for the presence of A. pleuropneumoniae on the tonsils and for antibodies to A. pleuropneumoniae using bacteriological and serological techniques, respectively. (dtu.dk)
  • The cumulative proportion of pigs carrying A. pleuropneumoniae in their tonsils increased significantly between the age of 4-12 weeks. (dtu.dk)
  • This age period corresponded to the age at which the proportion of pigs with detectable levels of colostral antibodies to the different serotypes of A. pleuropneumoniae was declining. (dtu.dk)
  • Actinobacillus pleuropneumoniae hfq mutants strains are attenuated for virulence in pigs , impaired in the ability to form biofilms , and more susceptible to stress, but knowledge of the extent of sRNA involvement is limited. (bvsalud.org)
  • However, field observation suggests that most infected pigs eventually become immune, then cease to shed virus by 60 days post-infection. (iastate.edu)
  • The purpose of this paper is to describe two clinical cases of PRRSV-infected weaned pigs where Tilmovet AC (tilmicosin phosphate) was administered via water to control PRRSV infection and to present data on viremia, antibody titers, clinical and production parameters and severity of PRRS infection. (huvepharma.com)
  • PCR results verify early PRRS infection in a low percentage of pigs. (huvepharma.com)
  • As clinical signs are subtle, pigs may not show any signs of disease, the growth rates may be reduced, and may be more susceptible to other (respiratory) infections. (dechra.fr)
  • Bacterial expression profiles of A. pleuropneumoniae isolated from lung lesions of 25 infected pigs were compared in samples taken 6, 12, 24 and 48 hours post infection. (nih.gov)
  • It is additionally indicated for treatment of acute outbreaks of respiratory disease in pigs caused by strains of Actinobacillus pleuropneumoniae and Pasteurella multocida susceptible to florfenicol. (veterinarymedicinedrugs.com)
  • Treatment of outbreaks of respiratory diseases in pigs caused by Actinobacillus pleuropneumoniae and Pasteurella multocida susceptible to florfenicol. (vet-agro.pl)
  • Subclinically infected pigs tend to be more susceptible to co-infections due to their compromised immune system. (msd-animal-health.ie)
  • As a feature of PCVD immunosuppression pigs may also show signs of secondary bacterial or superimposed viral or fungal infections such as PRRS, E. coli enteritis, Salmonellosis and Haemophilis Parasuis (Glässers Disease). (msd-animal-health.ie)
  • Chronic stress caused for example by high stocking density, large groups in the gestation stage and reduced birth weight may influence social interaction in pigs negatively and lead to disturbances in the ontogenesis of the immune system and / or in the defense against infection. (uzh.ch)
  • Actinobacillus pleuropneumoniae is another possible cause of pneumonia in potbellied pigs. (net-capacity.com)
  • A. pleuropneumoniae doesn't survive for long outside of its host, so your pig will need to come into direct contact with infected pigs to get sick. (net-capacity.com)
  • This is because potbellied pigs have a small lung capacity compared to other animals, and this makes lung infections more serious. (net-capacity.com)
  • This is because the two species of bacteria that can cause pneumonia in pigs- M. hyopneumoniae and A. pleuropneumoniae - are species-specific. (net-capacity.com)
  • Porcine pleuropneumonia induced by Actinobacillus pleuropneumoniae ( A.p ) and enzootic pneumonia due to primarily M ycoplasma hyopneumoniae ( M. hyo )belong to most important and widely spread diseases of pigs. (ceva.vn)
  • Vaccination against M. hyopneumoniae has been shown to be effective in reducing lung lesions and improving growth rate, FCE and the general health of the pigs but does not totally eliminate the disease or the infection. (octagon-services.co.uk)
  • In the present study, serotype 9 strains isolated from a country where infection due to this serotype is endemic (Spain), were compared to those recovered from Canada, where this serotype is rarely isolated from diseased pigs. (biomedcentral.com)
  • Several bacterial combinations are seen in vivo, the most common simultaneous infection being Pasteurella multocida. (wikipedia.org)
  • Florfenicol injection is indicated for preventive and therapeutic treatment of respiratory tract infections in cattle due to Mannheimia haemolytica, Pasteurella multocida and Histophilus somni. (veterinarymedicinedrugs.com)
  • Control and treatment of respiratory diseases caused by Pasteurella multocida (Pasteurellosis), Actinobacillus pleuropneumoniae (Pleuropneumonia), Streptococcus suis (Streptococcosis) or Haemophilus parasuis (Glasser's disease). (egyeurogroup.com)
  • Treatment of secondary infections in Chronic Respiratory Disease caused by E.coli , Pasteurella multocida , Salmonella spp . (egyeurogroup.com)
  • Treatment of respiratory infections caused by Mannheimia haemolytica, Pasteurella multocida and Histophilus somni susceptible to florfenicol. (vet-agro.pl)
  • Treatment of acute outbreaks of swine respiratory disease caused by strains of Actinobacillus pleuropneumoniae and Pasteurella multocida susceptible to florfenicol. (farmacy.co.uk)
  • Cytotoxic necrotizing factor production by hemolytic strains of Escherichia coli causing extraintestinal infections. (microbiologyresearch.org)
  • As a facultative anaerobic pathogen, A. pleuropneumoniae may need CO2 to grow. (wikipedia.org)
  • Vaccines can be prophylactic (to prevent or ameliorate the effects of a future infection by a natural or "wild" pathogen ), or therapeutic (to fight a disease that has already occurred, such as cancer ). (webot.org)
  • Host-pathogen interactions and responses to infection are dynamic processes involving multiple pathways in the immune system. (webot.org)
  • The transcriptional profile of the porcine lung pathogen, Actinobacillus pleuropneumoniae, was monitored during the acute phase of infection in its natural host. (nih.gov)
  • In this work we describe the immunoproteomic characterization of OMVs from Actinobacillus pleuropneumoniae (App), a Gramnegative pathogen of wonderful veterinary interest, in the context of vaccine development. (caspaseinhibitor.com)
  • Haemophilus influenzae, expressing cell-surface adhesins including N-Glc, to establish a connection between H. influenzae infection and MS. We exploited the biosynthetic machinery from the opportunistic pathogen H. influenzae (and the homologous enzymes from A. pleuropneumoniae) to produce a unique set of defined glucosylated adhesin proteins. (unifi.it)
  • Riboflavin could also be involved in modulating host immune responses, which might increase the pathogen clearance from host cells and increase host defense against microbial infections. (bioseek.eu)
  • Although A.p is a primary pathogen which doesn't require previous triggering to produce the disease, M. hyo can increase the severity of A.p infection. (ceva.vn)
  • On the Taiwan farm, diverse bacterial pathogens ( G parasuis , M hyopneumoniae , A pleuropneumoniae ) were present during the experiment. (huvepharma.com)
  • A superstimulation of the immune system was also not the trigger as it is forbidden to immunize against PRRSV, M hyopneumoniae and A. pleuropneumoniae. (uzh.ch)
  • Nineteen different serotype variants (serovars) have been recognized for A. pleuropneumoniae, based on the different capsular polysaccharides exhibited. (wikipedia.org)
  • Overall design: A 84 chip study using total RNA recovered from A. pleuropneumoniae serotype 2 (4226) and serotype 6 (7712640) isolated from infected pig lung tissue during the first 48 of infection. (nih.gov)
  • Of these diseases, epididymitis and orchitis in rams (caused by A. seminis ), sleepy foal disease (caused by A. equuli ), porcine pleuropneumonia (caused by A. pleuropneumoniae ) and pyogranulomatous lesions of the soft tissues of the head - in particular the oral cavity or the forestomachs of cattle, sheep and goats - (caused by A. lignieresii) occur most commonly. (anipedia.org)
  • Objective】 Through genome sequencing and bioinformatics analysis of GD2107 strain of multi-drug resistant Actinobacillus pleuropneumoniae (APP),the genome database information of APP was enriched,the phylogenetic tree based on Apx Ⅳ gene was constructed,and the evolutionary relationship of the strain was analyzed,so as to provide reference for exploring the pathogenic mechanism of APP and clinical prevention and control of porcine infectious porcine contagious pleuropneumia (PCP). (chvm.net)
  • PCVD has been associated with Porcine Dermonephrotic Syndrome (PDNS) and reproductive failure and infection is presented clinically by mortality, ill- thrift (wasting), paleness, dyspnoea (difficulty breathing), intermittent diarrhoea and visibly enlarged lymph nodes. (msd-animal-health.ie)
  • Whole Genome Sequencing and Biological Characteristics Analysis of Multidrug-resistant Actinobacillus pleuropneumoniae GD2107 Strain[J]. China Animal Husbandry and Veterinary Medicine, 2022, 49(10): 4019-4031. (chvm.net)
  • There can be many causes of abortion, from infection to noninfectious causes such as exposure to toxins in the environment or genetics. (edu.vn)
  • 3] SHIN M,KANG M L,CHA S B,et al.An immunosorbent assay based on the recombinant ApxⅠa,ApxⅡa,and ApxⅢa toxins of Actinobacillus pleuropneumoniae and its application to field sera[J]. Journal of Veterinary Diagnostic Investigation ,2011,23(4):736-742. (chvm.net)
  • Differences in virulence potential, immunogenicity, and worldwide geographical distribution contribute to the diversity of the A. pleuropneumoniae serotypes. (wikipedia.org)
  • Several virulence factors account for the remarkable pathogenicity of A. pleuropneumoniae. (wikipedia.org)
  • Actinobacillus pleuropneumoniae biofilms: Role in pathogenicity and potential impact for vaccination development. (matters-of-activity.de)
  • Impact of Actinobacillus pleuropneumoniae biofilm mode of growth on the lipid A structures and stimulation of immune cells. (matters-of-activity.de)
  • Surface Polysaccharide Mutants Reveal that Absence of O Antigen Reduces Biofilm Formation of Actinobacillus pleuropneumoniae. (matters-of-activity.de)
  • Mouse-models for H. pylori infections and imaging approaches (CSLM and SEM) to characterize the biofilm structure its components. (skander-hathroubi.net)
  • Several studies have illustrated the therapeutic efficacy of photoactivated riboflavin against nosocomial infections and multidrug resistant bacterial infections as well as microbial associated biofilm infections, revealing the potential role of riboflavin as a promising antimicrobial candidate, which could serve as one of the alternatives in fighting the global crisis of the emergence of antimicrobial resistance seen in different pathogenic microbes. (bioseek.eu)
  • Hence, this review aimed to provide some insights on the promising role of riboflavin as an antimicrobial candidate and also a host immune-modulator from a multi-perspective view as well as to discuss the application and challenges on using riboflavin in photodynamic therapy against various pathogens and microbial biofilm-associated infections. (bioseek.eu)
  • Infection and Immunity , 84 (1): 127-137. (matters-of-activity.de)
  • Thus, the dual effects of riboflavin on both pathogens and host immunity, reflected by its potent bactericidal effect and alleviation of inflammation in host cells further imply that riboflavin could be a potential candidate for therapeutic intervention in resolving microbial infections. (bioseek.eu)
  • 2. Escherichia coli infections are widely distributed among poultry of all ages and categories. (edu.vn)
  • Cytokines produced during urinary tract infection induced by Escherichia coli challenge include tumor necrosis factor (TNF), interleukin-1 (IL-1), IL-6, and IL-8 (2, 15, 37), while another study showed local production of these cytokines during experimental Actinobacillus pleuropneumoniae infection of the lung (4). (zsfy.org)
  • 5] STRINGER O W,LI Y,BOSS J T,et al.Rapid detection of Actinobacillus pleuropneumoniae from clinical samples using recombinase polymerase amplification[J]. Frontiers in Veterinary Science ,2022,9:805382. (chvm.net)
  • Actinobacillus pleuropneumoniae is a nonmotile, Gram-negative, encapsulated coccobacillus bacterium found in the family Pasteurellaceae. (wikipedia.org)
  • Sugar-phosphates were present in normal and infected intestinal mucus and stool samples, indicating that these metabolites are available within the intestinal lumen for enteric bacteria to import during infection. (rcsb.org)
  • Before I retired from Miami University, my interests were in the mechanisms bacteria use to infect human beings and cause disease, and how we can use this knowledge to prevent infection by bacterial pathogens. (miamioh.edu)
  • These opportunistic anaerobic bacteria may also cause bed sores, pressure sores, aspiration pneumonia, chronic otitis media (ear infection), chronic sinusitis, and osteomyelitis (bone infection). (microgeninc.com)
  • MMA syndrome and urinary infections caused by association of gram+ and gram- bacteria. (egyeurogroup.com)
  • Here, using A. pleuropneumoniae strain MIDG2331 ( serovar 8), 14 sRNAs were identified by co-immunoprecipitation with Hfq and the expression of eight, identified as trans-acting sRNAs, were confirmed by Northern blotting . (bvsalud.org)
  • causes bacterial meningitis, fulminating septicaemia, pulmonary and ophthalmic infections, chronic synovitis (joint pain/inflammation), skin diseases, wound infections and postoperative urinary tract infections. (microgeninc.com)
  • This migration causes damage in the liver (milk spots) and in the lungs (coughing, secondary bacterial infections e.g. (dechra.fr)
  • In some cases, infection is manifested as an epidemic of respiratory disease or reproductive failure but in other outbreaks, infection may spread slowly. (iastate.edu)
  • RIEMERELLA ANATIPESTIFER INFECTIONS 82.Riemerella anatipestifer (RA) infection is a contagious disease in domestic ducks, turkeys and other fowl. (edu.vn)
  • It is well known that pulmonary alveolar macrophages (PAMs) are the primary target of PRRSV infection and location of virus replication. (huvepharma.com)
  • 14 However, A. pleuropneumoniae requires a Staphylococcus feeder culture, or a nicotinamide adenine dinucleotide (NAD) supplement in media intended for its growth. (anipedia.org)
  • Necrotic enteritis (NE) is an acute Clostridium infection characterized by severe necroses of intestinal mucosa. (edu.vn)
  • As the infection worsens, lung-specific symptoms will develop. (net-capacity.com)
  • It has been shown that the mixed infection doubles the size of the lung lesion (Ciprian et al, 1986). (octagon-services.co.uk)
  • Our study shows that AfuABC-dependent uptake of sugar-phosphates plays a critical role during enteric bacterial infection and uncovers previously unrecognized roles for these metabolites as important contributors to successful pathogenesis. (rcsb.org)
  • These results indicate that extracellular actin enhances haemolysin production by E. coli and may have implications in the pathogenesis of E. coli infections. (microbiologyresearch.org)
  • Actinobacillus pleuropneumoniae was found to be the causative agent for up to 20% of all bacterial pneumonia cases in swine. (wikipedia.org)
  • Each chip measures the expression level of 4,876 target genes from A. pleuropneumoniae with each gene covered by an average of 26.7 probes. (nih.gov)
  • The World Health Organization (WHO) reports that licensed vaccines are currently available for twenty-five different preventable infections . (webot.org)
  • 6. Approaches to the treatment of soft tissue infection and diabetic foot. (frontiersin.org)
  • 1] ZHANG L,WU X,HUANG Z,et al.Pharmacokinetic/pharmacodynamic assessment of cefquinome against Actinobacillus pleuropneumoniae in a piglet tissue cage infection model[J]. Veterinary Microbiology ,2018,219(6):100-106. (chvm.net)
  • They may have tissue loss in their lungs due to the infection, and you may notice that they have recurring respiratory problems. (net-capacity.com)
  • causes severe respiratory infections in the immunocompromised. (microgeninc.com)
  • causes a rare infection of the lungs and is associated with asthma. (microgeninc.com)
  • Finally, worm infections can pave the way for respiratory infections leading to mortality and/or additional treatment cost. (dechra.fr)
  • Enrofloxacin was developed by Bayer for the treatment of broad spectrum of bacterial infections in animals (cats and dogs). (ncats.io)
  • Although some studies suggest that when bacterial infections are occurring simultaneously with PCV2 infection, marginal benefits may be gained from antibiotic treatment. (msd-animal-health.ie)