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  • biopsy
  • However, in the remaining cases, pleural biopsy is required. (wikipedia.org)
  • 12 13 CECT is recommended as the next investigation, with a view to subsequent histological diagnosis (blind, image-guided or thoracoscopic pleural biopsy). (bmj.com)
  • 15 Hitherto, the role of TUS has been limited to pleural fluid detection (with high sensitivity) and image-guided techniques (thoracocentesis, drain placement, lung biopsy). (bmj.com)
  • From 1994-2015,3316 pleural effusions are included in our date base by a protocol(pH, biochemical,ADA,count cell,cytology and biopsy). (ersjournals.com)
  • The last 100 MPE confirmed by cytology or closed pleural biopsy have been studied. (ersjournals.com)
  • large pleural
  • In large pleural effusions, mediastinal shift usually occurs away from the side of the effusion unless co-existing bronchial obstruction is present, in which case the mediastinum may be central or shifted toward the effusion. (oncologynurseadvisor.com)
  • However, the surgical removal of large pleural deposits with infusion of hyperthermic chemotherapy may offer significant survival and symptomatic benefit for patients in this disease category. (wikipedia.org)
  • The goal of surgical cytoreduction is to remove all gross disease including tumors that are in resectable areas of the lung or other structures and any large pleural nodules. (wikipedia.org)
  • mesothelial
  • Pleuritis Pleural mesothelial hyperplasia Pleural calcified fibrous pseudotumor Pleural plaques: discrete fibrous or partially calcified thickened area which can be seen on X-rays of individuals exposed to asbestos. (wikipedia.org)
  • parietal pleura
  • The discovery of malignant cells in pleural fluid and/or parietal pleura signifies disseminated or advanced disease and a reduced life expectancy in patients with cancer. (bmj.com)
  • Pleural plaques are discrete circumscribed areas of hyaline fibrosis (patches of thickening) of the parietal pleura and rarely the visceral pleura that develop 20 to 40 years after first exposure. (wikipedia.org)
  • Diffuse pleural thickening (DPT) is non-circumscribed fibrous thickening of the visceral pleura with areas of adherence to the parietal pleura and obliteration of the pleural space. (wikipedia.org)
  • Mesothelioma
  • The diagnosis can be elusive, particularly in the context of malignant mesothelioma, where interpretation of pleural fluid cytology and pleural biopsies is a challenging specialist field. (oncologynurseadvisor.com)
  • The third Italian consensus conference for malignant pleural mesothelioma: state of the art and recommendations," Critical Reviews in Oncology/Hematology , vol. 104, pp. 9-20, 2016. (hindawi.com)
  • 3 13 14 Few studies have estimated the proportion of pleural effusions due to mesothelioma: studies from 1975, 1985 and 1987 identified mesothelioma in 1/271, 3/472 and 22/592 patients, respectively, but there are no more recent data to update this in light of the increasing incidence of mesothelioma. (bmj.com)
  • 15 16 In malignant mesothelioma, one study has shown an association between increasing pH and increasing survival. (bmj.com)
  • Other common causes include pleural mesothelioma and lymphoma. (wikipedia.org)
  • Pleural fluid mesothelin has a sensitivity of 71%, greater than that of cytology, and a specificity of 89% for the diagnosis of malignant mesothelioma. (wikipedia.org)
  • Exposure to asbestos particles in the air increases the risk of developing malignant mesothelioma. (wikipedia.org)
  • In this trial GL-ONC1 infection of tumor cells was identified in 6 out of 8 patients with epithelioid malignant pleural mesothelioma. (wikipedia.org)
  • This caused an epidemic of malignant mesothelioma (MM) that reached an incidence 300 times that expected in populations not exposed to asbestos. (wikipedia.org)
  • The relation to asbestos was identified when, a few months later, two consecutive patients appeared with massive pleural effusions that proved to be malignant mesothelioma. (wikipedia.org)