Loading...
  • patient's
  • A low platelet count can affect a patient's ability to produce healthy blood cells and even stop bleeding during surgical procedures. (redcrossblood.org)
  • It is similar to the ristocetin cofactor assay but has the added benefit in that it helps in the diagnosis of type 2B/pseudo von Willebrand disease (vWD) and Bernard-Soulier syndrome because it uses patient's live endogenous platelets, whereas ristocetin cofactor assay tests the function of only the vWF and not the platelets. (wikipedia.org)
  • abnormal
  • Giant platelets cannot stick adequately to an injured blood vessel walls, resulting in abnormal bleeding when injured. (wikipedia.org)
  • However, if repeated blood testing shows a prolonged, unexplained elevation of platelet numbers and misshapen or abnormal platelets, a physician should investigate. (ehow.co.uk)
  • Usually with Leukemia and Lymphoma one will have more than just a platelet lab abnormal. (medhelp.org)
  • The abnormal platelet reaction following EDTA exposure is thought to be caused by a plasma factor, although not an immunoglobulin. (wikipedia.org)
  • bone
  • According to a Japanese study, vitamin D plays a valuable role in the function of hematopoietic stem cells, cells in the bone marrow that give rise to red blood cells, white blood cells, and platelets. (pdsa.org)
  • Platelets have no cell nucleus: they are fragments of cytoplasm that are derived from the megakaryocytes of the bone marrow, and then enter the circulation. (wikipedia.org)
  • They are the functional equivalents of platelets, but circulate as intact mononuclear cells, and are not simply cytoplasmic fragments of bone marrow megakaryocytes. (wikipedia.org)
  • Platelets are small anucleate blood cells that that are produced by megakaryocytes in the bone marrow, and also likely in the lungs. (els.net)
  • As the number of cancer cells increases in the bone marrow, normal bone marrow cells are crowded out, resulting in fewer platelet-producing cells. (medhelp.org)
  • Though PDGF is synthesized, stored (in the alpha granules of platelets), and released by platelets upon activation, it is also produced by other cells including smooth muscle cells, activated macrophages, and endothelial cells Recombinant PDGF is used in medicine to help heal chronic ulcers and in orthopedic surgery and periodontistry as an alternative to bone autograft to stimulate bone regeneration and repair. (wikipedia.org)
  • inflammation
  • Platelets have been implicated in a variety of physiological and pathological processes including inflammation, immune regulation, atherosclerosis, angiogenesis and lymphatic vessel development, liver regeneration and tumour metastasis. (els.net)
  • Particular focus is put on platelets as a link between haemostasis and inflammation contributing to both. (springer.com)
  • Platelets, inflammation and tissue regeneration" (PDF). (wikipedia.org)
  • These vegetables also have vitamins and minerals that reduce inflammation and have been known to help increase platelet count. (ehow.co.uk)
  • donors
  • Large-scale manufacturing by pooling many platelet donors is a necessity to mitigate the donor-to-donor variability. (wikipedia.org)
  • Platelets must be transfused within just 5 days after donation - so there is a constant, often critical need for new and current donors to give to keep up with hospital demand. (redcrossblood.org)
  • These can stimulate production of alloantibodies, (antibodies against other people's antigens) in recipients of transfused platelets from donors with different HPAs. (wikipedia.org)
  • count
  • Below is a sampling of vitamins and other supplements-along with associated research-that may have some potential to improve platelet count and/or symptoms of ITP. (pdsa.org)
  • In PDSA's Survey of Non-Traditional Treatments for ITP , about 30 percent of the people who took vitamin K felt it helped their platelet count and bleeding symptoms. (pdsa.org)
  • A platelet count is often ordered as a part of a complete blood count, which may be done at an annual physical examination. (medhelp.org)
  • I will tell you that I noticed a difference in my platelet count when I took certain antibotics. (healthboards.com)
  • I have always had sinus problems and my doctor gave me Bioxin once for it and not only did the sinus infection go away but my platelet count dropped from 965 to 850. (healthboards.com)
  • The fact that most gathering devices capture a percentage of a given thrombocyte count could bias results, because of inter-individual variability in the platelet concentration of human plasma and more would not necessarily be better. (wikipedia.org)
  • Low Platelets Count? (medhelp.org)
  • I hope your grandmother's physicians are closely monitoring her platelet count. (medhelp.org)
  • From my experience, physicians will give platelets to a patient when their platelet count is around 20,000 or less. (medhelp.org)
  • The platelet count can reach levels of over 2 million per microliter. (ehow.co.uk)
  • If you have a low platelet count, it is harder for the blood to form clots. (ehow.co.uk)
  • There are several foods that you can eat that can help you increase the platelet count in your blood, but you should always see you physician for monitoring of the condition. (ehow.co.uk)
  • Its kind of scary, but being that I was in the hospital yesterday for 8 hours under treatment for kidney stones (not the reason for the high platelet count), they let me go, so it can't be TOO bad. (medhelp.org)
  • There are various conditions that are not cancer than can cause a low platelet count. (medhelp.org)
  • Platelet count less than specified. (nationwidechildrens.org)
  • cofactor
  • Ristocetin cofactor assay uses platelet-poor plasma (with vWF but no platelets) and adds ristocetin and exogenous formalin-fixed platelets which can passively agglutinate (but not actively "aggregate", as they are dead). (wikipedia.org)
  • Screening tests and bioassay of von Willebrand's factor(platelet aggregating factor) in human and animal blood plasma areeffected using a reagent of blood platelets and snake venom havinga positive platelet aggregating cofactor effect. (rti.org)
  • The reagentmay comprise dried platelets and either ristocetin or active snakevenom as the platelet aggregating cofactor. (rti.org)
  • concentrate
  • Platelet-rich plasma (PRP) is a concentrate of platelet-rich plasma protein derived from whole blood, centrifuged to remove red blood cells. (wikipedia.org)
  • For preparation of PRP, various protocols are used, with an underlying principle of concentrating platelets to 3-5 times physiological levels, then injecting this concentrate in the tissue where healing is desired. (wikipedia.org)
  • mesenchymal
  • Platelet lysate is commonly used for supplementation of basal media in mesenchymal stem cells culture. (wikipedia.org)
  • Platelet lysate consisting of a natural repair proteome supports human mesenchymal stem cell proliferation and chromosomal stability. (wikipedia.org)