Loading...
  • anti platelet
  • Patients allocated in the two study arms will receive the same anti platelet treatment, except for the administration of the loading dose, which will be only administered to patients allocated in Group 2. (clinicaltrials.gov)
  • Subsequent studies found that various other dihydroxy-E,Z,E-double bound-configured PUFA but not those with E,E,E or E,E,Z double bond configurations share with PDX anti-platelet activity. (wikipedia.org)
  • Other biologically active dihydroxy-E,Z,E-PUFA have not been tested for but, based on the studies cited above, are projected to possess anti-platelet activity. (wikipedia.org)
  • Vorapaxar is a new anti-platelet drug that is part of the PAR-1 antagonist family, a new class of anti-platelet drug. (wikipedia.org)
  • concentrations
  • The enzyme is thought to be involved in regulating many different intracellular processes, such as: aldosterone secretion from the adrenal gland intracellular concentrations of cAMP in cardiomyocytes and of cAMP and cGMP in platelets cGMP in neurons and effect on long-term memory barrier function of endothelial cells under inflammatory conditions (See review articles ) Several enzyme functions have been reported for the PDE2. (wikipedia.org)
  • It has also been suggested that PDE2 might play an important role in the regulation of elevated intracellular concentrations of cAMP and cGMP in platelets. (wikipedia.org)
  • Patient's
  • It is similar to the ristocetin cofactor assay but has the added benefit in that it helps in the diagnosis of type 2B/pseudo von Willebrand disease (vWD) and Bernard-Soulier syndrome because it uses patient's live endogenous platelets, whereas ristocetin cofactor assay tests the function of only the vWF and not the platelets. (wikipedia.org)
  • Uremia
  • Platelet function analysis utilizing platelet-rich plasma and optical density based aggregometry fails to identify patients at risk for uremia associated complications. (hindawi.com)
  • Whole blood platelet analysis detected platelet dysfunction which may be associated with bleeding and thrombotic risks in uremia. (hindawi.com)
  • factors
  • This product segment is expected to grow at the highest CAGR in the next five years, owing to factors such as continuous technological advancements in the field of sensors and detectors, rising trend of automation of platelet aggregation testing procedures, growing adoption & market preference for automated instruments among diagnostic laboratories, and improved patient compliance offered by point-of-care testing analyzers as compared to conventional instruments. (marketsandmarkets.com)
  • Factors like continuous technological improvement, rising trend in platelet aggregation testing market and growing adoption will tend to grow product segment with highest CAGR in forecast period. (sbwire.com)
  • Studies
  • Blood will be drawn via venopuncture for laboratory studies (WBPa, platelet factor 4, beta thromboglobulin and VWF antigen levels and activity). (utsouthwestern.edu)
  • This report studies the Platelet Aggregation System development status and future trend in China, focuses on top players in China, also splits Platelet Aggregation System by type and by applications, to fully and deeply research and reveal the market general situation and future forecast. (reportsnreports.com)
  • measures
  • We quantify aggregation through changes in particle size histograms and associated measures (e.g. total number of particles). (rice.edu)
  • The coalescence equation gives rise to so-called "population balance measures" of aspects of particles pertinent to their aggregation behavior. (rice.edu)
  • Kinetic data from shear-induced aggregation indicate two population balance measures are important: the particle collison efficiency, (epsilon), and the particle void volume fraction, (phi). (rice.edu)
  • These and other kinetic measures indicate rapid activation (within ten seconds) of platelets in the shear field above a threshold shearing rate of about 2000 sec('-1) but diminishing platelet adhesiveness upon continued shear stress exposure. (rice.edu)
  • blood
  • platelets , a part of blood, clump together and cause blood to clot. (floridahealthfinder.gov)
  • The laboratory specialist will look at how the platelets spread out in the liquid part of the blood (plasma) and whether they form clumps after a certain chemical or drug is added. (floridahealthfinder.gov)
  • When platelets clump together, the blood sample is clearer. (floridahealthfinder.gov)
  • platelet aggregation, hypercoagulable state - blood. (floridahealthfinder.gov)
  • On the basis of end user, the global platelet aggregation devices market is classified into standalone hospitals, diagnostic laboratories, research & academic institutes, and other end users (blood banks & pharmaceutical-biotechnology companies).Standalone hospitals segment is expected to account for the largest share of the global market in 2015. (marketsandmarkets.com)
  • On the basis of end users, the platelet aggregation market categorized into diagnostic laboratories, academia, standalone hospitals and blood bank. (sbwire.com)
  • These recently classified metabolites are distinguished from the many other dihydroxy-PUFA with three conjugated double bonds that do not have this critical E,Z,E configuration: they inhibit the function of platelets and therefore may be involved in controlling and prove useful for inhibiting human diseases which involve the pathological activation of these blood-borne elements. (wikipedia.org)
  • patients
  • Furthermore, the activation of platelets was also related to circulation and vascular damage in patients with hypertension and diabetes [ 6 ]. (hindawi.com)
  • This platelet hyperreactivity may be associated with a thrombotic diathesis as seen in some uremic patients. (hindawi.com)
  • Because of treprostinil's inhibiting effect on platelet aggregation, there is an increased risk of bleeding, especially among patients who are also taking anticoagulants. (wikipedia.org)
  • affect
  • an interviewer-administered assessment of diet and exercise with a modified 24-hour dietary recall and the Stanford 7-day Physical activity Recall will be performed to ensure dietary consistency which may affect platelet aggregability on visit 1. (utsouthwestern.edu)