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  • abnormally
  • In addition, low MPV can correlate with abnormally small platelet size, sometimes a symptom of a spectrum referred to as Wiskott-Aldrich Syndrome (WAS), caused by a genetic mutation of the WAS gene. (wikipedia.org)
  • Clinical
  • Human Platelet Lysate (or hPL) is a substitute supplement for fetal bovine serum (FBS) in experimental and clinical cell culture. (wikipedia.org)
  • The first commercially available platelet lysate used to grow clinical trial grade MSC was PLTMax® made available by Mill Creek Life Sciences in 2010. (wikipedia.org)
  • Some companies provide different grades of platelet lysate including GMP versions and clinical grade for use in human clinical trials. (wikipedia.org)
  • antibodies
  • Some of these antibodies by accident kill platelets. (thebody.com)
  • Platelet antibodies may be directed to a number of antigenic "targets" carried on platelet cytoplasmic membranes. (labcorp.com)
  • 14-16 According to the American Society for Hematology practice guideline, routine evaluation for platelet reactive antibodies in the evaluation of ITP is not recommended while testing for HIV and HCV should be considered in all patients with acute ITP. (labcorp.com)
  • 1,5,17 In this condition, which can be considered to be the platelet equivalent of hemolytic disease of the newborn (HDN), maternal antibodies cross the placenta and destroy fetal platelets. (labcorp.com)
  • We and others have shown that flow-cytometric analysis of platelets with the use of epitope-dependent monoclonal antibodies or fluorochrome-labeled ligands provides sensitive and specific assessment of platelet activation. (ahajournals.org)
  • There were no platelet antibodies detected. (wikipedia.org)
  • count
  • Below is a sampling of vitamins and other supplements-along with associated research-that may have some potential to improve platelet count and/or symptoms of ITP. (pdsa.org)
  • In PDSA's Survey of Non-Traditional Treatments for ITP , about 30 percent of the people who took vitamin K felt it helped their platelet count and bleeding symptoms. (pdsa.org)
  • Platelet count less than specified. (nationwidechildrens.org)
  • In Jan t cell started to fall and viral load going up along with low platelet count. (thebody.com)
  • In end of Feb tcell went to 356 and viral load to 1000.My platelet count fell to 38. (thebody.com)
  • Although the normal platelet count is usually above 150,000 (the actual value depends on the laboratory performing this measurement), a human being can live quite well with a platelet count over 20,000. (thebody.com)
  • Only if the platelet count falls below 20,000 or below 10,000, then patients spontaneously bleed in the gums, nose, bowels and so on. (thebody.com)
  • So if your platelet count settles in the range between 38,000 (what you call 38) and 69,000 (what you call 69), the advise of your doctor is quite sound, i.e. just watch and wait. (thebody.com)
  • If you need to have surgery (e.g. a dental extraction), then at that point, you should take some action (and there are many possibilities) to raise your platelet count for whatever procedure is being planned. (thebody.com)
  • He also noticed that my platelet count was 600-something and wants to send me to a blood specialist. (medhelp.org)
  • I told him that I've been told before that my platelet count was higher than normal, and was sent to donate but never sent to a blood specialist. (medhelp.org)
  • I just had A CBC on 4-30-08 and my platelet count was 316,000. (dailystrength.org)
  • Wow, thats great about your platelet levels, i am on Prednisone at the moment and my last count was 100,000. (dailystrength.org)
  • I went to the hema today and my platelets was 316,000 and my white count along with my hemoglobin was still normal. (dailystrength.org)
  • The main symptom of low blood platelet count is bleeding, which can present itself in many ways. (ehow.co.uk)
  • People also may suffer from low platelet count due to a chronic liver condition. (ehow.co.uk)
  • If your low blood platelet count is due to ITP, you will likely be treated with immunosuppressants, which hinder the immune system from destroying platelets. (ehow.co.uk)
  • If your low platelet count is caused by the treatment for hepatitis C or by chemotherapy, a doctor will likely reduce the amount you are receiving and monitor platelets carefully. (ehow.co.uk)
  • Platelet transfusion , also known as platelet concentrate, is used to prevent or treat bleeding in people with either a low platelet count or poor platelet function . (wikipedia.org)
  • He was hospitalized for 5 days and treated with a cocktail of drugs (doxycycline, prednisone, sucralfate, & azithioprine among them) at that time his platelet count was around 3,000 and red cell count was a little on the low end, all other blood work and urine samples came back normal. (vetinfo.com)
  • In a case in which platelets were low, in combination with a high white blood cell count and anemia, I would be concerned about the possibility of Evan's syndrome, which is ITP and IMHA occurring at the same time. (vetinfo.com)
  • The CCI is calculated as follows: CCI= (Post-transfusion platelet count - Pre-transfusion platelet count)(BSA) ÷ (number of platelets transfused). (wikipedia.org)
  • citation needed] Immune-mediated refractoriness usually shows little or no increment in the immediate post-transfusion platelet count. (wikipedia.org)
  • Non-immune refractoriness may show an initial rise in platelet count, but a subsequent 8-hour or 12-hour post-transfusion sample shows a return to the baseline platelet count. (wikipedia.org)
  • symptoms
  • In PDSA's Survey of Non-Traditional Treatments for ITP about 30 percent of those who tried vitamin C felt it helped their platelets and bleeding symptoms, with about 10 percent claiming there was a sustained effect. (pdsa.org)
  • If you notice any of the symptoms of low blood platelets, you should seek medical attention. (ehow.co.uk)
  • Platelet transfusion is the main treatment for people presenting with bleeding symptoms. (wikipedia.org)
  • Bernard-Soulier Disease (Giant Platelet Syndrome) Symptoms, Causes, Treatment - What is Bernard-Soulier syndrome? (wikipedia.org)