G(M2) Activator ProteinSphingolipid Activator ProteinsMacrophagesNeuronal PlasticityMacrophage ActivationSaposinsMacrophages, PeritonealG(M2) GangliosideTranscription Factor AP-1Macrophages, AlveolarCells, CulturedTissue Plasminogen ActivatorMolecular Sequence DataPromoter Regions, GeneticCyclic AMP Receptor ProteinBase SequencePlasminogen Activator Inhibitor 1Transcription FactorsUrokinase-Type Plasminogen ActivatorCell LineMice, Inbred C57BLbeta-N-AcetylhexosaminidasesDNA-Binding ProteinsTranscription, GeneticProto-Oncogene Proteins c-junRNA, MessengerHexosaminidase AB-Cell-Specific Activator ProteinGene Expression RegulationPhagocytosisSignal TransductionMacrophage Colony-Stimulating FactorLipopolysaccharidesTrans-ActivatorsTranscription Factor AP-2Mice, KnockoutLong-Term PotentiationGangliosidosesProtein BindingProto-Oncogene Proteins c-fosSynapsesBinding SitesMonoglyceridesAmino Acid SequenceGangliosidoses, GM2Time FactorsEnzyme ActivationMonocytesTranscriptional ActivationNF-kappa BMutationMacrophage Migration-Inhibitory FactorsTumor Necrosis Factor-alphaRecombinant ProteinsEscherichia coliTay-Sachs DiseaseBacterial ProteinsNeuronsReceptors, Urokinase Plasminogen ActivatorPlasminogen ActivatorsMice, Inbred BALB CCytokinesTransfectionPhosphorylationHippocampusCell DifferentiationGlycosphingolipidsKineticsHexosaminidase BGlycoproteinsBlotting, WesternGene ExpressionInflammationProteinsDose-Response Relationship, DrugReceptors, Cyclic AMPSynaptic TransmissionDNAImmunohistochemistryRats, Sprague-DawleyUp-RegulationPhenotypeIfosfamideReverse Transcriptase Polymerase Chain ReactionRepressor ProteinsReceptors, Cell SurfaceDisease Models, AnimalLeukodystrophy, MetachromaticMitogen-Activated Protein KinasesExcitatory Postsynaptic PotentialsThioglycolatesTetradecanoylphorbol AcetateGene Expression Regulation, BacterialLysosomesFos-Related Antigen-2RNA Polymerase Sigma 54Long-Term Synaptic DepressionJNK Mitogen-Activated Protein KinasesPlasmidsPeritoneal Cavity