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Transcription FactorsTranscription, GeneticCell MembraneMolecular Sequence DataDNA-Binding ProteinsPromoter Regions, GeneticPAX7 Transcription FactorMuscle Fibers, SkeletalBase SequenceGene Expression RegulationSatellite Cells, Skeletal MuscleCell LinePaired Box Transcription FactorsPAX2 Transcription FactorProtein BindingSp1 Transcription FactorMuscle, SkeletalBinding SitesRNA, MessengerAmino Acid SequenceCells, CulturedSignal TransductionMembrane LipidsMutationTrans-ActivatorsMembranesGene Expression Regulation, DevelopmentalCell DifferentiationMuscle DevelopmentHomeodomain ProteinsTranscriptional ActivationIntracellular MembranesRepressor ProteinsTransfectionNuclear ProteinsBasic Helix-Loop-Helix Transcription FactorsProtein TransportTranscription Factor AP-1Cell NucleusMembrane PotentialsModels, BiologicalRecombinant Fusion ProteinsForkhead Transcription FactorsRegenerationPlasmaProtein Structure, TertiaryHeLa CellsDNAMyoblastsMyofibrilsMice, Inbred C57BLReverse Transcriptase Polymerase Chain ReactionBlotting, WesternMembranes, ArtificialGene ExpressionBasic-Leucine Zipper Transcription FactorsCloning, MolecularTime FactorsTranscription Factor AP-2Mice, KnockoutMembrane ProteinsCarrier ProteinsImmunohistochemistryGenes, ReporterPAX9 Transcription FactorMicroscopy, FluorescenceMusclesMice, Inbred mdxMicroscopy, ElectronMice, TransgenicMembrane FluidityKruppel-Like Transcription FactorsMyoD ProteinSequence Homology, Amino AcidChromatin ImmunoprecipitationTranscription Factors, TFIIErythrocyte MembraneGreen Fluorescent ProteinsPlasmidsCell Membrane PermeabilityPhenotypeSaccharomyces cerevisiae ProteinsDystrophinSTAT3 Transcription FactorCalciumFluorescent Antibody TechniqueYY1 Transcription FactorGATA4 Transcription FactorCell Line, TumorTranscription Factor TFIIDMuscular Dystrophy, AnimalPhosphorylationNFATC Transcription FactorsRecombinant ProteinsNF-kappa BMicroscopy, ConfocalSaccharomyces cerevisiaeActivating Transcription Factor 3Muscle ProteinsGene Expression Profiling
PAX3MyogenicMuscularExpressionMuscle
PAX35
  • Associated Genetic Factors: PAX3 and c-Met Mutations in PAX3 can cause a failure in c-Met expression. (wikipedia.org)
  • PAX3 mediates the transcription of c-Met and is responsible for the activation of MyoD expression-one of the functions of MyoD is to promote the regenerative ability of satellite cells (described below). (wikipedia.org)
  • PAX3 is needed for the transcription of c-Met. (wikipedia.org)
  • Associated Genetic Factors: PAX3, c-Met, Mox2, MSX1, Six, Myf5, and MyoD Mox2 (also referred to as MEOX-2) plays an important role in the induction of mesoderm and regional specification. (wikipedia.org)
  • We demonstrate that mdPCR can give exact molecule counts per cell for mRNA isoforms encoding the myogenic transcription factor Pax3. (biomed.news)
Myogenic3
Muscular2
  • Each stage has various associated genetic factors lack of which will result in muscular defects. (wikipedia.org)
  • Testosterone elicits significant muscular effects and abnormalities of plasma concentrations can cause muscle disease ( 13 ). (frontiersin.org)
Expression2
  • Serum response factor (SRF) plays a central role during myogenesis, being required for the expression of striated alpha-actin genes. (wikipedia.org)
  • In addition, the injection of CNCbl could accelerate the process of mouse muscle injury repair, enlarge the diameter of newly formed myofibers and upregulate the expression of MYH2, PAX7, CD320, Acvr1, p-Smad2 and p-Smad3 in vivo. (bvsalud.org)
Muscle4
  • These consequences further reveal the complexity of myogenesis and the importance of each genetic factor in proper muscle development. (wikipedia.org)
  • Testosterone concentrations decline as age increase, suggesting that low plasma testosterone levels can cause or accelerate muscle- and age-related diseases, as sarcopenia. (frontiersin.org)
  • However, the pathophysiological mechanisms underlying this muscle syndrome and its relationship with plasma level of androgens are not completely understood. (frontiersin.org)
  • Originally discovered as axon guidance factors, they have been implicated in cancer progression, embryonal organogenesis, skeletal muscle innervation, and other physiological and developmental functions in different tissues. (biomed.news)