• 2 The central role of HJV in body iron homeostasis is supported by the evidence that Hjv knockout mice ( Hjv − / − mice) show severe suppression of hepatic hepcidin and increased iron deposition in the liver, pancreas and heart. (haematologica.org)
  • Hepcidin has strong antimicrobial activity against E.coli ML35P N.cinerea and weaker antimicrobial activity against S.epidermidis, S.aureus and Group B streptococcus bacteria. (wikipedia.org)
  • It appears as though many peptides initially isolated as and termed "antimicrobial peptides" have been shown to have more significant alternative functions in vivo (e.g. hepcidin). (wikipedia.org)
  • Is it time to replace hemoglobin testing with hepcidin testing? (nutrition.org)
  • Erythroferrone, produced in erythroblasts, has been identified as inhibiting hepcidin and so providing more iron for hemoglobin synthesis in situations such as stress erythropoiesis. (wikipedia.org)
  • Results of the first international round robin for the quantification of urinary and plasma hepcidin assays: need for standardization. (ru.nl)
  • CONCLUSIONS: The secondary reference material identified in this study has the potential to substantially improve equivalence between hepcidin measurement procedures and contributes to the establishment of a traceability chain that will ultimately allow standardization of hepcidin measurement results. (ox.ac.uk)
  • Eleven plasma hepcidin measurement procedures (5 mass spectrometry based and 6 immunochemical based) quantified native individual plasma samples (n = 32) and native plasma pools (n = 8) to assess analytical performance and current and achievable equivalence. (ox.ac.uk)
  • RESULTS: Absolute hepcidin values and reproducibility (intrameasurement procedure CVs 2.9%-8.7%) differed substantially between measurement procedures, but all were linear and correlated well. (ox.ac.uk)
  • Linear regression analysis and standardized residuals showed that a candidate reference material consisting of native lyophilized plasma with cryolyoprotectant was commutable for all measurement procedures. (ox.ac.uk)
  • The objective of this study was to determine if abdominal subcutaneous adipose tissue (AbScAT) releases hepcidin in vivo and if release is modified by obesity. (hindawi.com)
  • Urinary hepcidin excretion in patients with low grade myelodysplastic syndrome. (ru.nl)