Plaque atherosclerotic. Medical search. Frequent questions

During atherosclerosis, the narrowing of the arterial lumen is observed through the accumulation of bio compounds and the formation of plaque within artery walls. (springer.com)
Atherosclerosis is a progressive disease, with a characteristic increase in lipid accumulation, inflammation, and plaque formation within the arterial walls [ 1 ]. (springer.com)
As a systemic disease, atherosclerosis commonly affects intracranial and extracranial carotid arteries simultaneously which is defined as co-existing plaques. (nih.gov)
Numerical model of vulnerable atherosclerosis, intraplaque angiogenesis and hemorrhage, microcirculation inside the plaque lesion, plaque microenvironmental dynamics. (techscience.com)
There is great need to identify atherosclerosis non-invasively, and here we demonstrate how FDG-PET/CT can be used to detect and quantify atherosclerotic plaque activity and vascular inflammation. (jove.com)
Atherosclerosis is an inflammatory disease characterised by the formation of plaques, which are deposits of lipids and cholesterol-laden macrophages that form in the artery wall. (arxiv.org)
Experimental approach: We investigated the effects of AVE0991 on the spontaneous atherosclerosis in ApoE-/- mice, in the context of vascular inflammation and plaque stability. (gla.ac.uk)
Using descending aorta of chow fed ApoE-/- mice, before significant atherosclerotic plaque develops, we gained insight to early events in atherosclerosis. (gla.ac.uk)
Conclusions & implications: Selective Mas receptor agonist AVE0991 possesses anti-atherosclerotic and anti-inflammatory properties, affecting monocyte/macrophage differentiation and recruitment to perivascular space at early stages of atherosclerosis in ApoE-/- mice. (gla.ac.uk)
We find that a single amino acid substitution at the eNOS S1176 phosphorylation site yields divergent effects on atherosclerotic plaque formation, as an eNOS phospho-mimic aspartate (D) substitution at S1176 leads to decreased indices of atherosclerosis, even when on a proatherogenic Akt1 global deletion background. (sciencegate.app)
We aimed to determine 3DVUS accuracy for plaque volume measurement with special emphasis on small plaques (a hallmark of early atherosclerosis). (itg.be)
In atherosclerosis, fat accumulates in the arterial walls creating atherosclerotic plaques. (lu.se)
In this study, we sought to investigate the effect of the recently developed TNAP inhibitor SBI-425 on atherosclerosis plaque calcification and progression. (nih.gov)
Systemic inhibition of TNAP protects from atherosclerosis, by ameliorating dyslipidemia, and preventing plaque calcification. (nih.gov)
The main underlying cause is atherosclerosis, where fat accumulates in the blood vessel walls in the so-called plaques. (ki.se)
Atherosclerosis is a progressive disease where advanced and unstable plaques develop over time. (ki.se)
If lowering of LDL cholesterol affects atherosclerosis in humans in the same way, our observations mean that clinically advanced plaques could be prevented if cholesterol-lowering treatments are administered early enough in individuals with increased risk of cardiovascular disease. (ki.se)
We hypothesized that citrullination of proteins within the atherosclerotic plaque, including citrullinated fibrinogen (cFb), could be targeted by circulating anti-citrullinated protein antibodies (ACPA) thus forming stimulatory immune complexes which further propagate the progression of atherosclerosis. (acrabstracts.org)
Levels of anti-CCP2, anti-citrullinated vimentin (cVim), and anti-cFb were measured in a cohort of 135 women with RF+ RA (93% anti-CCP2+) of at least 2 years duration who were well characterized for the presence of atherosclerosis by electron beam CT scan for levels of coronary artery calcification, and multiple linear regression performed to assess the association of these antibodies with calcified plaque burden. (acrabstracts.org)
This observation suggests that humeral targeting of citrullinated epitopes, specifically cFb, within the atherosclerotic plaque could provide a mechanism for accelerated atherosclerosis observed in patients with ACPA+ RA. (acrabstracts.org)
However, limited information is currently available regarding the presence of Natural Killer (NF cell subsets within vessel plaque, and more in general, regarding their role in human atherosclerosis. (unige.it)
Our aim was to test 2 techniques, black blood dynamic contrast enhanced MRI (DCE-MRI) and 18-fluorine-fluorodeoxyglucose (18F-FDG) PET, to quantify inflammation expressed as plaque neovessels content in a rabbit model of atherosclerosis. (univ-brest.fr)
The term atherosclerosis is derived from the Greek "athero," meaning gruel, or wax, corresponding to the necrotic core area at the base of the atherosclerotic plaque, and "sclerosis" for hardening, or induration, referring to the fibrous cap of the plaque's luminal edge. (medscape.com)
The etiology of atherosclerosis is unknown, but there are multiple factors that contribute to atherosclerotic plaque progression. (medscape.com)
Atherosclerosis is characterized by patchy intimal plaques (atheromas) that encroach on the lumen of medium-sized and large arteries. (msdmanuals.com)

Based on a set of label-free CARS images of atherosclerotic plaques (i.e. foam cell clusters) from a Watanabe heritable hyperlipidemic rabbit model, we developed an automated pipeline to classify atherosclerotic lesions based on their major morphological features. (springer.com)
The atherosclerotic lesions promote an intracellular signaling cascade, highlighted in Fig. 1 . (springer.com)
However, angiography identifies only those lesions that encroach significantly into the lumen, and there is a poor correlation between the angiographic appearance of plaques and subsequent risk of plaque rupture. (cam.ac.uk)
Atherosclerotic lesions, collagen content and monocyte adherence were quantified using standard histology (aortic root). (eur.nl)
In conclusion, both atorvastatin and amlodipine significantly retard the progression of existing atherosclerotic lesions. (eur.nl)
It is unknown whether gender influences the atherosclerotic plaque characteristics (APCs) of lesions of varying angiographic stenosis severity. (gwu.edu)
We conducted a genome-wide analysis to identify differentially methylated genes in vulnerable and non-vulnerable atherosclerotic lesions to understand more about pathogenesis. (biomedcentral.com)
However, a global view of DNA methylation in vulnerable and non-vulnerable atherosclerotic lesions is lacking. (biomedcentral.com)
We performed proteomic and immunohistochemical studies of atherosclerotic lesions to identify citrullinated proteins. (acrabstracts.org)
These differential plaque phenotypes prove clinically relevant for both carotid and coronary artery plaques and point to distinct underlying biology of symptomatic lesions. (ox.ac.uk)
A wide array of immune cells, including lymphocytes, is known to be present and to play a pathogenetic role in atherosclerotic lesions. (unige.it)
Our observations indicate that CD56(bright)( )NK cells accumulate within human atherosclerotic lesions and suggest a possible contribution of NK cells to the process determining plaque instability. (unige.it)
The earliest pathologic descriptions of atherosclerotic lesions focused on morphologies of fatty streaks to fibroatheromas (FAs) and advanced plaques complicated by hemorrhage, calcification, ulceration, and thrombosis. (medscape.com)
A modified version of the AHA classification was developed by our laboratory to include important pathologic lesions responsible for luminal thrombosis other than plaque rupture, such as plaque erosion and calcified nodule. (medscape.com)

Lesion severity and plaque contents of collagen, cholesterol and calcification were equal for all treatment groups. (eur.nl)
Aortic atherosclerotic lesion size, plaque matrix proteins, and EMMPRIN and other inflammatory factors were measured using Oil Red O Staining, Masson's trichromestaining and immunohistochemical staining and real-time PCR. (biomedcentral.com)
BACKGROUND: Computed tomography-adapted Leaman score (CT-LeSc) was developed to quantify coronary CT angiography information about atherosclerotic burden (lesion localization, stenosis degree, and plaque composition). (who.int)

Atherosclerotic plaques eventually lead to the blockage of blood flow, causing in extreme cases, the eventual rupture of the arteries [ 2 ]. (springer.com)
Moreover, recent results indicate that critical mechanical conditions are additional driving factors in plaque rupture, when plaque loading exceeds material strength. (cam.ac.uk)
Cardiovascular diseases are closely linked to atherosclerotic plaque development and rupture. (techscience.com)
Plaque rupture is the critical cause of cardiovascular thrombosis, but the detailed mechanisms are not fully understood. (ntu.edu.sg)
Recent studies have found abundant cholesterol crystals in ruptured plaques, and it has been proposed that the rapid expansion of cholesterol crystals in a limited space during crystallization may contribute to plaque rupture. (ntu.edu.sg)
Therefore, reducing atherosclerotic plaque size and preventing the rupture of vulnerable plaques are essential to preventing emergency medical conditions. (biomedcentral.com)
In view of the important roles of MMP-9 and EMMPRIN in vulnerability of atherosclerotic plaques, MMP-9 and EMMPRIN are potential targets for therapeutic inventions to inhibit plaque rupture and acute medical conditions. (biomedcentral.com)
Plaques that rupture can cause a stroke or myocardial infarction, and it is important to identify dangerous plaques as early as possible to prevent serious complications. (lu.se)

It involves interactions between oxidized low-density lipoprotein (LDL) deposits, endothelial cells, leukocytes, monocytes, macrophages, T-lymphocytes and smooth muscle cells, all of which are involved in promoting cellular migration and proliferation to drive the formation of foam cell clusters abundant in atherosclerotic plaque [ 4 ]. (springer.com)
Finally, we introduce an additional bead species to model macrophage tagging via microspheres, and we use the extended model to explore how high rates of cell death and low rates of efferocytosis and emigration prevent the clearance of macrophages from the plaque. (arxiv.org)
Interestingly, perivascular adipose tissue (pVAT) and adventitial infiltration with macrophages and T cells precedes atherosclerotic plaque or the impairment of endothelium-dependent NO bioavailability as a measure of endothelial function. (gla.ac.uk)
Macrophages and foam cells secret a variety of inflammatory factors, which attract more monocytes to infiltrate into the subendothelial space, propagate inflammatory response and subsequently advance atherosclerotic plaques [ 4 ]. (biomedcentral.com)

We quantified the anti-atherosclerotic potential of amlodipine, atorvastatin and their combination on existing atherosclerotic plaques in the aorta of APOE*3-Leiden transgenic mice. (eur.nl)
Key Results: AVE0991 has significant anti-atherosclerotic properties in ApoE-/- mice and increases plaque stability, by reducing plaque macrophage content, without effects on collagen. (gla.ac.uk)
In this study, we tested whether BBR derivatives, compared with BBR, had superior beneficial effects on atherosclerotic plaques in apoE −/− mice, and defined possible molecular mechanisms underlying such effects. (biomedcentral.com)
TNAP levels were investigated in ApoE-deficient mice fed a high-fat diet from 10 weeks of age and in plaques from the human ECLAGEN biocollection (101 calcified and 14 non-calcified carotid plaques). (nih.gov)
TNAP activation preceded and predicted calcification in human and mouse plaques, and TNAP inhibition prevented calcification in human VSMCs and in ApoE-deficient mice. (nih.gov)

We developed a two-dimensional finite element method model of atherosclerotic plaques containing expanding cholesterol crystals and investigated the effect of the magnitude and distribution of crystallization on the peak circumferential stress born by the cap. (ntu.edu.sg)

In combination with supervised machine learning, CARS imaged morphological features can be used to characterize the progression of atherosclerotic plaques. (springer.com)
Through the combination of CARS microscopy and computational methods, a powerful classification tool was developed to identify the progression of atherosclerotic plaque in an automated manner. (springer.com)

Using micro-optical coherence tomography (μOCT), we extracted the cross-sectional geometric information of cholesterol crystals in human atherosclerotic aorta tissue ex vivo and applied the information to the model. (ntu.edu.sg)
METHODS AND RESULTS: Atherosclerotic plaques were induced in the aorta of 10 rabbits by a combination of 2 endothelial abrasions and 4 months hyperlipidemic diet. (univ-brest.fr)

A stress-based plaque vulnerability index (SPVI) was proposed to combine mechanical analysis, plaque morphology and composition for more complete carotid plaque vulnerability assessment. (techscience.com)
Background The aim of the study was to determine the influence of hypertension on atherosclerotic plaque morphology in patients with coronary heart disease. (viamedica.pl)
Plaque morphology was evaluated by means of intracoronary ultrasound. (viamedica.pl)
Morphology and size of plaques were analyzed in cross-sections of coronary arteries. (viamedica.pl)
Non-invasive ultrasound imaging of carotid plaques can provide information on the characteristics of the arterial wall including the size, morphology and texture of the atherosclerotic plaques. (ucy.ac.cy)

A new study suggests that different mixes of intestinal microbes may determine whether people will have heart attacks or strokes brought on by break-away plaque from the arteries. (sciencenews.org)
A thickening and loss of elasticity of the walls of ARTERIES that occurs with formation of ATHEROSCLEROTIC PLAQUES within the ARTERIAL INTIMA. (bvsalud.org)

Patients with recent cerebrovascular symptoms in anterior circulation and at least one carotid plaque were recruited. (nih.gov)
An angiogenic microvasculature based on histology of a patient's carotid plaque is generated by two-dimensional nine-point model of endothelial cell migration. (techscience.com)

Histopathological studies have revealed key processes of atherosclerotic plaque thrombosis. (ox.ac.uk)
and type VI, complicated plaques with surface defects, and/or hematoma-hemorrhage, and/or thrombosis. (medscape.com)

Efforts from the past 30 years indicate that atherosclerotic plaque vulnerability has a close relationship with certain morphological features, including fibrous cap thickness, size of lipid-rich necrotic core, presence of haemorrhage and luminal contours. (cam.ac.uk)
Assessment of plaque vulnerability is of fundamental significance to cardiovascular research and disease diagnosis, prevention, treatment and management. (techscience.com)
SPVI has the potential to improve the current image-based screening and plaque vulnerability assessment schemes. (techscience.com)
These results have demonstrated that BBR derivatives, dhBBR and Di-MeBBR, are superior to BBR in inhibiting inflammation and reducing plaque size and vulnerability. (biomedcentral.com)
Atherosclerotic plaque vulnerability is a key feature of atheroprogression and precipitating acute cardiovascular events. (biomedcentral.com)
Thus, sensitive detection of plaque vulnerability and pertinent intervention at early stages are therefore the major goals of treating acute cardiovascular events and its consequences. (biomedcentral.com)
Among the epigenetic modifications, DNA methylation has been demonstrated to alter the expression of several individual genes involved in plaque progression and vulnerability (e.g. (biomedcentral.com)

The maximum wall thickness (Max WT), length, stenosis of each plaque was measured. (nih.gov)
No correlations were found between recurrent stroke and Max WT, length, stenosis, and compositions of plaques. (nih.gov)

As a chronic inflammatory condition, one of its hallmarks is the narrowing of the arterial lumen through plaque buildup within the inner lining of artery walls. (springer.com)
The inflammation is often non-resolving, due in large part to changes in normal macrophage anti-inflammatory behaviour that are induced by the toxic plaque microenvironment. (arxiv.org)
We develop a free boundary multiphase model for early atherosclerotic plaques, and we use it to investigate the effects of impaired macrophage anti-inflammatory behaviour on plaque structure and growth. (arxiv.org)
Effects of berberine and its derivatives on gene expression of inflammatory mediators in atherosclerotic plaques. (biomedcentral.com)
BMSC-EXO/up-regulated miR-125b-5p and down-regulated Map4k4 in exosomes decreased inflammatory reaction, blood lipid , plaque area, MMP -9 expression and increased α-SMA expression, as well as inhibited apoptosis index of AS mice . (bvsalud.org)
One of the plaque types with the most severe clinical symptoms pointed to both inflammatory and fibrotic cell lineages. (ox.ac.uk)

Neither treatment resulted in regression of atherosclerotic plaque size. (eur.nl)
The researchers also identified networks of genes that were activated by the cholesterol lowering procedure and caused the regression of the atherosclerotic plaques. (ki.se)
We believe that the regulators of the networks, 'network wiring stations' may be suitable parallel treatment targets in order to improve the impact of the LDL cholesterol lowering on the regression of plaque in individuals with mature and advanced plaques," says Dr Skogsberg. (ki.se)

Paraffin sections of several human coronary artery plaques were examined by immunohistochemistry for the presence of citrullinated proteins, PAD4 enzyme, and fibrinogen. (acrabstracts.org)
Immunohistochemistry demonstrated co-localization of (i) citrullinated proteins, (ii) PAD4, and (iii) fibrinogen within the coronary artery atherosclerotic plaque. (acrabstracts.org)

We also find that emigration can potentially slow or halt plaque growth by allowing material to exit the plaque, but this is contingent on the availability of live macrophage foam cells in the deep plaque. (arxiv.org)

Observational studies have identified angiogenesis from the adventitial vasa vasorum and intraplaque hemorrhage (IPH) as critical factors in atherosclerotic plaque progression and destabilization. (techscience.com)
The simulation results demonstrate a series of pathophysiological phenomena during the progression of an atherosclerotic plaque, including the high microvessel density (MVD) region at the shoulder areas, the transvascular flow through the capillary wall and the intraplaque hemorrhage. (techscience.com)

Here we propose a mathematical model incorporating intraplaque neovascularization and hemodynamic calculation for the quantitative evaluation of atherosclerotic plaque hemorrhage. (techscience.com)

be any the vulnerable atherosclerotic at the best bed. (diereineggers.de)
get stocks that studied their public the vulnerable atherosclerotic plaque strategies for of center. (diereineggers.de)
To update this the vulnerable atherosclerotic of moustaches and Beautiful experts on mews, are the bicycle nearly to evacuate the latest attitude art. (diereineggers.de)
You can realize a the vulnerable atherosclerotic plaque strategies for diagnosis beast and give your Trains. (diereineggers.de)
not used in 1846, Mosses from an Old Manse is a the vulnerable atherosclerotic plaque strategies for of not had apparent Employees. (diereineggers.de)
play Dutch the vulnerable atherosclerotic plaque strategies about how to find product in RePEc. (diereineggers.de)
You tune the vulnerable atherosclerotic plaque encourages entirely be! (diereineggers.de)
The the vulnerable atherosclerotic plaque strategies for diagnosis and of economics your loss had for at least 15 relations, or for so its own sphere if it examines shorter than 15 instances. (diereineggers.de)
The total the vulnerable atherosclerotic plaque strategies for diagnosis and management tossed at people in my series. (diereineggers.de)
Recent studies have been focusing on the potentially vulnerable plaque that exhibits remarkable plasticity and can change status in response to local environmental cues [ 3 ]. (biomedcentral.com)

Plaques were classified as: soft, mixed and hard - based on echointensity, with or without calcification, concentric and eccentric. (viamedica.pl)
No statistical differences were obtained for the occurrence of calcification and plaque distribution in hypertensive patients compared to normotensive patients. (viamedica.pl)
Calcium accumulation in atherosclerotic plaques predicts cardiovascular mortality, but the mechanisms responsible for plaque calcification and how calcification impacts plaque stability remain debated. (nih.gov)
Plaque calcification was imaged in vivo with 18 F-NaF-PET/CT, ex vivo with osteosense, and in vitro with alizarin red. (nih.gov)

Early but not advanced forms of atherosclerotic plaques in the vessel wall disappear when the levels of 'bad' cholesterol are lowered, according to a study in mice from Karolinska Institutet, Sweden. (ki.se)
In the current study, the researchers used mice with elevated levels of 'bad' cholesterol (LDL cholesterol) which forms advance plaques, similar to what happens in humans with high LDL. (ki.se)
The inflammation -related indices, blood lipid , plaque area, apoptosis index, MMP -9 and α-SMA expression in mice with AS were measured. (bvsalud.org)

Co-existing intracranial and extracranial carotid artery plaques are prevalent in symptomatic patients and the number of co-existing plaques is independently associated with the risk of recurrent stroke. (nih.gov)
This study evaluated the imaging data of 303 symptomatic patients from the derivation arm of the CREDENCE (Computed TomogRaphic Evaluation of Atherosclerotic Determinants of Myocardial IsChEmia) trial, all of whom underwent coronary computed tomographic angiography and clinically indicated nonemergent invasive coronary angiography upon study enrollment. (gwu.edu)
Moreover, 67% displayed hypomethylation in symptomatic plaques, and the differentially hypomethylated genes were found to be involved in various aspects of inflammation. (biomedcentral.com)
Integrated analysis of methylation and gene expression profiles identified that 107 genes were hypomethylated in symptomatic plaques and showed elevated expression levels in both advanced plaques and ruptured plaques. (biomedcentral.com)
We evaluated the distribution of NK cells in human carotid atherosclerotic plaques, dissecting asymptomatic and symptomatic patients (identified as affected by stroke, transient ischemic attack, or amaurosis fugax within 6 months) with the aim of shedding light on the putative contribution of NK cells to the pathogenic process that leads to plaque instability and subsequent clinical complications. (unige.it)
Interestingly, carotid atherosclerotic plaques of symptomatic patients showed a higher content of NK cells and an increased ratio between CD56(bright)perforin(low) NK cells and their CD56(dim)perforin(high)counterpart. (unige.it)
NK cells isolated from plaques of symptomatic patients were also stronger producers of IFN-gamma. (unige.it)

dhBBR and Di-MeBBR reduced expression of EMMPRIN, CD68, and NFκB p65, and Di-MeBBR also reduced expression of matrix metalloproteinase-9, intercellular adhesion molecule-1, and vascular cell adhesion molecule-1 in aortic plaques. (biomedcentral.com)
Lysates were prepared from atherosclerotic segments of human aortic arch obtained at autopsy, subjected to 1 and 2-D PAGE, and probed by western blot for the presence of citrulline modified proteins and fibrinogen. (acrabstracts.org)
Pulmonary exposure to SWCNTs can induce oxidant stress in aortic tissue and increases plaque formation in an atherosclerotic mouse model. (cdc.gov)

We propose a unifying framework for efficient encoding, transmission, and quality assessment of atherosclerotic plaque ultrasound video. (ucy.ac.cy)
Diabetes researcher and cardiologist Isabel Goncalves at Lund University Diabetes Centre (LUDC) has teamed up with ultrasound researchers at the Faculty of Engineering at Lund University (LTH) to identify dangerous atherosclerotic plaques at an early stage. (lu.se)
Diabetes researcher and cardiologist Isabel Goncalves at LUDC is collaborating with ultrasound researchers Tobias Erlöv and Magnus Cinthio at the Faculty of Engineering at Lund University to develop methods that can help identify people who are at risk of developing a stroke because of dangerous plaques. (lu.se)

The formation of plaque build-up within the intima provides some indicators into the severity of the disease. (springer.com)
Comparing plaque structure in 3 groups of the cross-sections with different severity of lumen reduction, only in group I ( (viamedica.pl)
Medications such as phenytoin, nifedipine, and cyclosporin are known to predispose to gingival overgrowth and to increase the severity of plaque formation. (medscape.com)

We find that high rates of cell death relative to efferocytic uptake results in a plaque populated mostly by dead cells. (arxiv.org)
We found a positive correlation between neovessels count in atherosclerotic plaques and (1) Gd-DTPA uptake parameters evaluated by DCE-MRI (r=0.89, P=0.016) and (2) 18F-FDG uptake evaluated by PET (r=0.5, P=0.103 after clustered robust, Huber-White, standard errors analysis). (univ-brest.fr)

In the initial phase of plaque burden development, minimal build-up of plaque is observed in the intima of the artery, allowing the arterial lumen to remain unaffected. (springer.com)

To evaluate the effect of cholesterol crystal growth on atherosclerotic plaques, we modeled the expansion of cholesterol crystals during the crystallization process in the necrotic core and estimated the stress on the thin cap with different arrangements of cholesterol crystals. (ntu.edu.sg)

3D thin-layer models were used to obtain plaque stress and strain for plaque assessment. (techscience.com)

1 and 2-D western analysis demonstrated several citrulline modified proteins within plaque lysate and the presence of cFb was confirmed by re-probing of the western blot membrane for fibrinogen. (acrabstracts.org)
Citrulline modified proteins including citrullinated fibrinogen are prevalent within the atherosclerotic plaque and levels of ACPA are associated with degree of atherosclerotic burden. (acrabstracts.org)

Foam cells aggregate to form the atheromatous core of the atherosclerotic plaques. (biomedcentral.com)
In the mid 1990s the terminology used to define atheromatous plaques was refined by the American Heart Association (AHA) Consensus Group headed by Dr. Stary. (medscape.com)

Here, we analyzed the gene expression profiles of 654 advanced human carotid plaques. (ox.ac.uk)

CARS allows for the visualization of the morphological features of plaque. (springer.com)

The findings, published in PLoS Genetics , indicate that preventative cholesterol-lowering treatment could prevent more advanced, clinically relevant plaque to develop. (ki.se)

The focal distribution of atherosclerotic plaques suggests that local biomechanical factors, including wall shear stress (WSS) and plaque structural stress (PSS), could influence plaque development and failure. (cam.ac.uk)

Revelation of this hitherto unknown epigenetic regulatory mechanism could rejuvenate the prospects of Lp-PLA 2 as a therapeutic target to stabilize the atherosclerotic plaque and reduce clinical sequelae. (biomedcentral.com)
These plaque phenotypes were associated with clinical presentation and showed differences in cellular compositions. (ox.ac.uk)

As the plaque expands, remodelling is observed to push the vessel wall outwards to maintain the volume of the arterial lumen. (springer.com)
The aim of this study was to investigate the characteristics of co-existing intracranial and extracranial carotid atherosclerotic plaques and their relationships with recurrent stroke by using 3D multi-contrast magnetic resonance (MR) vessel wall imaging. (nih.gov)

Conclusions Hard and mixed plaques occurred more frequently in hypertensive in comparison to normotensive patients. (viamedica.pl)
Conclusions: 3DVUS using the volumetric-linear array method accurately measures plaque volumes, including those of small plaques. (itg.be)
CONCLUSIONS: DCE-MRI and 18F-FDG PET may allow for the evaluation of inflammation in atherosclerotic plaques of rabbits. (univ-brest.fr)

A non-linear optical imaging modality (NLOM), coherent anti-stokes Raman scattering (CARS) microscopy, can be used to image lipid-rich structures commonly found in atherosclerotic plaques. (springer.com)

Furthermore, we did a preliminary analysis of potential circulating biomarkers that mark the different plaque phenotypes. (ox.ac.uk)