• A 6-day-old infant girl died as the result of a placental abruption. (wiselawoffices.com)
  • I have a patient who suffered a placental abruption and preterm birth of a stillborn infant en route to the hospital. (aapc.com)
  • Adverse pregnancy outcomes were defined as a pregnancy affected by gestational hypertension, preeclampsia, eclampsia, preterm birth, small for gestational age infant, or placental abruption. (aboutlawsuits.com)
  • Placental abruption and long-term maternal cardiovascular disease mortality: a population-based registry study in Norway and Sweden. (uib.no)
  • An international contrast of rates of placental abruption: An age-period-cohort analysis. (uib.no)
  • COPENHAGEN - Here's reassuring news for pregnant women with rheumatic diseases treated with tumor necrosis factor alpha (TNFα) inhibitors: although the drugs vary widely in their transmissibility across the placenta, there appears to be no excess risk for serious infections in children exposed in utero to TNF inhibitors with high, compared with low, placental transfer. (medscape.com)
  • Because Hg can interfere with placental functioning and cross the placenta to target the fetal brain, prenatal Hg exposure can inhibit fetal growth and development directly and indirectly. (nih.gov)
  • The relationship between methylation of HTR2A in the placenta and neurodevelopmental outcomes, evaluated using the NICU Network Neurobehavioral Scales (NNNS), was assessed in newborn infants (n = 444). (nih.gov)
  • The researchers also found altered immune activity (measured by changes in RNA transcripts) in the placenta and cord blood of infants born to infected mothers. (nih.gov)
  • Placental insufficiency or utero-placental insufficiency is the failure of the placenta to deliver sufficient nutrients to the fetus during pregnancy, and is often a result of insufficient blood flow to the placenta. (wikipedia.org)
  • The impact of mycoestrogens on infant health may start early, with altered development of the placenta. (nih.gov)
  • The data suggest that neonatal hematologic effects of maternal preeclampsia, if related to the placenta, are associated with factors other than placental histology. (jefferson.edu)
  • Thus, placenta has remained the most accurate record of the infants' prenatal experience. (hindawi.com)
  • These complications include pregnancy-induced high blood pressure ( preeclampsia ), an underdeveloped placenta (placental insufficiency), early delivery, or pregnancy loss (miscarriage). (medlineplus.gov)
  • it also aborts placental transfusion leaving the child hypovolemic (low blood volume) and prone to anemia as a large amount of iron is left in the placenta. (natural-parenting.com)
  • Hofbauer cells are macrophages specific to the placenta and play a major role in placental development, infection response, and angiogenesis. (news-medical.net)
  • Subsequently, the expression of quantitative trait loci related to the previously identified placenta was used to calculate polygenic risk scores that predicted the expression of genes in the placental inflammation module. (news-medical.net)
  • the shortening and opening of the cervix during the first stage, descent and birth of the baby during the second, the delivery of the placenta during the third, and the recovery of the mother and infant during the fourth stage, which is referred to as the postpartum . (wikipedia.org)
  • To investigate the effects of interventions promoting placental transfusion at delivery (delayed cord clamping or umbilical cord milking) compared with early cord clamping on outcomes among premature neonates of less than 32 weeks of gestation. (nih.gov)
  • A systematic search was conducted of PubMed, Embase, and ClinicalTrials.gov databases (January 1965 to December 2013) for articles relating to placental transfusion strategies in very preterm neonates. (nih.gov)
  • We only included data from studies with an average gestational age of less than 32 weeks of gestation enrolled in randomized trials of enhanced placental-fetal transfusion interventions (delayed cord clamping or umbilical cord milking) compared with early cord clamping. (nih.gov)
  • Results of this meta-analysis suggest that enhanced placental transfusion (delayed umbilical cord clamping or umbilical cord milking) at birth provides better neonatal outcomes than does early cord clamping, most notably reductions in overall mortality, lower risk of intraventricular hemorrhage, and decreased blood transfusion incidence. (nih.gov)
  • 3 4 In this update, we focus on high income countries and provide a broad overview of extreme preterm birth epidemiology, recent changes, and best practices in obstetric and neonatal management, including new treatments such as antenatal magnesium sulphate or changes in delivery management such as delayed cord clamping and placental transfusion. (bmj.com)
  • Premature infants, who routinely have their cords clamped immediately, almost universally become anemic in the NICU, where the anemia is promptly corrected, sometimes by blood transfusion. (natural-parenting.com)
  • Any newborn that receives a full placental transfusion at birth has enough iron to prevent anemia during the first year of life. (natural-parenting.com)
  • 7] It is, therefore, reasonable to conclude that full placental transfusion (continuous oxygenation during birth, natural cord closure) will prevent the autism, mental retardation, behavioral disorders and learning disabilities that occur following infant anemia. (natural-parenting.com)
  • That's according to investigators at McGill University in Montreal, who studied outcomes for nearly 3000 infants who were exposed to TNF inhibitors during gestation. (medscape.com)
  • She added, however, that although the meta-analysis also showed little difference in outcomes for the children of women treated with high, compared with low, placental-transfer drugs, "we need more data to be sure about this. (medscape.com)
  • We examined potential associations between prenatal Hg exposure assessed through infant toenail Hg, placental DNA methylation changes, and newborn neurobehavioral outcomes. (nih.gov)
  • EMID2 hypomethylation may represent a novel mechanism linking in utero Hg exposure and adverse infant neurobehavioral outcomes. (nih.gov)
  • Placental FKBP5 genetic and epigenetic variation is associated with infant neurobehavioral outcomes in the RICHS cohort. (nih.gov)
  • Previously, Andersson and colleagues2 reported the outcomes of 4-month-old infants who were randomized to early vs late CC. They did not report any significant difference in scores using the Ages and Stages Questionnaire. (figshare.com)
  • Background: We evaluated the rates of placental pathologic lesions and their relationship with two-year neurodevelopmental outcomes in very-low-birth-weight (VLBW) infants. (unipv.it)
  • Conclusions: Placental pathologic findings such as severe MVM, FVM, and intravillous hemorrhage are significant predictors of neonatal survival and subsequent adverse neurodevelopmental outcomes. (unipv.it)
  • Maternal health has significant implications for birth outcomes and may predispose their infant/offspring to downstream effects that include craniofacial anomalies and associated dental and orofacial complications. (nih.gov)
  • They used these scores in a phenome-wide association study to determine whether this placental module was a reliable predictor of depressive and cardiovascular outcomes in adulthood. (news-medical.net)
  • Infants born with low birth weight are believed to be at higher risk of depressive outcomes and cardiovascular disease, as reported by early studies investigating the developmental origins of disease and health. (news-medical.net)
  • Furthermore, genomic studies have found that placental inflammation plays a significant role in shaping adult health outcomes. (news-medical.net)
  • In the present study, the researchers hypothesized that placental gene expression patterns related to inflammation in infants in non-pathogenic conditions would influence the health outcomes in adults. (news-medical.net)
  • The results reported that the loss or disruption of the homeostatic functions conducted by the Hofbauer cells due to placental infections or preterm delivery could increase the risk of depressive outcomes or cardiovascular disease in the adult stages of life. (news-medical.net)
  • She continues to be interested in the developmental origins of disease and optimizing neurodevelopmental outcomes for infants. (nastoolkit.org)
  • Adverse infant outcomes associated with discordant gestational age estimates. (uib.no)
  • Of 2105 offspring of mothers treated with a high placental-transfer drug, 38 (1.8%) had serious infections, compared with 10 of 797 offspring (1.3%) of mothers who received low placental-transfer drugs. (medscape.com)
  • HTR2A methylation was significantly higher in males and marginally higher in infants whose mothers reported tobacco use during pregnancy. (nih.gov)
  • Inflammatory immune responses triggered by the virus were observed in women, their neonates and placental tissues regardless of whether the mothers had symptoms. (nih.gov)
  • Infants born to infected mothers, even if the mother had no symptoms, had an inflammatory response reflected by higher levels of interleukin-8. (nih.gov)
  • Laboratory testing for congenital Zika virus infection is recommended for infants born to mothers with laboratory evidence of Zika virus infection during pregnancy, and for infants who have abnormal clinical findings suggestive of congenital Zika virus syndrome and a maternal epidemiologic link suggesting possible transmission, regardless of maternal Zika virus test results. (cdc.gov)
  • At this conclusion of today's session, the participant will be able to interpret revised testing guidance for newborn with possible congenital Zika virus infection, discuss clinical evaluation of infants born to mothers with laboratory evidence of Zika virus infection and outline outpatient management of infants with laboratory evidence of congenital Zika virus infection with, and without, abnormalities consistent with congenital syndrome. (cdc.gov)
  • We will also review the clinical evaluation of all infants born to mothers with lab evidence of Zika including the initial evaluation and outpatient management. (cdc.gov)
  • The infants of two other nursing mothers taking 200 mg daily and 400 mg daily, infant plasma levels dropped rapidly after birth. (drugs.com)
  • CDC has updated its interim guidance for U.S. health care providers caring for infants born to mothers with possible Zika virus infection during pregnancy ( 1 ). (cdc.gov)
  • In addition to infant Zika virus testing, initial evaluation of all infants born to mothers with laboratory evidence of Zika virus infection during pregnancy should include a comprehensive physical examination, including a neurologic examination, postnatal head ultrasound, and standard newborn hearing screen. (cdc.gov)
  • Hematologic effects of placental pathology on very low birthweight infants born to mothers with preeclampsia. (jefferson.edu)
  • OBJECTIVE: To investigate the effect of placental pathology on neonatal neutrophils, platelets, hematocrit and nucleated red blood cells in very low birthweight (VLBW) infants born to mothers with preeclampsia. (jefferson.edu)
  • CONCLUSION: In our population of VLBW infants born to mothers with preeclampsia, placental pathology was common. (jefferson.edu)
  • At birth, infants of mothers with antiphospholipid syndrome may be small and underweight. (medlineplus.gov)
  • Mothers' own milk is the best source of nutrition for nearly all infants. (mdpi.com)
  • A peripheral maternal blood smear was ni infants considered by their mothers to be made by finger prick. (who.int)
  • Future research can analyze the microbiomes of both infants and the placentas of their mothers. (livescience.com)
  • Elevated Acetoacetate and Monocyte Chemotactic Protein-1 Levels in Cord Blood of Infants of Diabetic Mothers. (childrens.com)
  • In the effort, the researchers will analyze more than 2,000 placental and matched blood samples obtained from mothers and infants in two separate cohorts. (genomeweb.com)
  • The effects of redistributing placental blood into healthy full-term newborns at birth by delayed umbilical cord clamping (CC) have been demonstrated in many studies.1 The short-term benefits include higher hemoglobin concentration after birth and increased iron stores until 6 months of age. (figshare.com)
  • Zika virus RT-PCR on placental tissues from women with possible Zika virus exposure can be considered for diagnostic purposes for symptomatic pregnant women and women with infants with possible Zika virus-associated birth defects without a definitive diagnosis of laboratory-confirmed Zika virus infection during pregnancy. (cdc.gov)
  • In today's COCA Call, we will discuss some background on the effects of Zika virus during pregnancy on the infant and updated recommendations for infant diagnostic testing and interpretation. (cdc.gov)
  • n Low birth weight in infants is linked to exposures to low-level arsenic during pregnancy. (nih.gov)
  • Data con- maternal (100/10 000 live births, 1991) and cerning personal and obstetric history, the infant (78.8/1000 live births, 1998) mortal- current pregnancy and pregnancy outcome ity rates have been recorded [ 8 ]. (who.int)
  • Smoking and socioeconomic deprivation were associated with an increased incidence of placental infection (p = 0.02) and ischaemia (p = 0.0001). (bmj.com)
  • The authors note that the key observation is that maternal infection with SARS-CoV-2 induces a fetal immune response even in the absence of placental infection or symptoms in the newborn. (nih.gov)
  • Based on results of the evaluation, testing of the infant for Zika virus infection could be considered. (cdc.gov)
  • I'm delighted to welcome you to today's COCA Call, Zika Update: Clinical Laboratory Testing and Care of Infants with Congenital Zika Infection . (cdc.gov)
  • A positive infant serum or urine rRT-PCR test result confirms congenital Zika virus infection. (cdc.gov)
  • Infants with laboratory evidence of congenital Zika virus infection should have a comprehensive ophthalmologic exam and hearing assessment by auditory brainstem response (ABR) testing before 1 month of age. (cdc.gov)
  • Recommendations for follow-up of infants with laboratory evidence of congenital Zika virus infection depend on whether abnormalities consistent with congenital Zika syndrome are present. (cdc.gov)
  • A wide range of neurologic abnormalities, in addition to microcephaly, has been observed among infants with presumed or confirmed congenital Zika virus infection ( 2 , 4 ). (cdc.gov)
  • In animal models, the enrichment of differentially regulated genes in the placental module was also explored for preterm birth, intraamniotic infection, and prenatal infection. (news-medical.net)
  • Expression of the genes in the placental module in Hofbauer cells was also examined for pregnancies where the mother had an active severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. (news-medical.net)
  • Preterm birth is often precipitated by intra-uterine infection, and the premature loss of placental function and, consequently, the aborted Hofbauer cell function results in a significantly higher risk of depression and cardiovascular disease. (news-medical.net)
  • Evidence suggesting an association of Zika virus infection with an increased risk for congenital microcephaly and other abnormalities of the brain and eye ( 5 ) prompted the World Health Organization to declare the Zika virus outbreak a Public Health Emergency of International Concern on February 1, 2016 ( http://www.who.int/mediacentre/news/statements/2016/1st-emergency-committee-zika/en/ external icon ). (cdc.gov)
  • IgM antibodies are immediate response antibodies within 30 days from infection and, because of their size, are not able to pass the placental barrier. (centerforhumanreprod.com)
  • Introduction Placental pathology provides a unique insight into the intrauterine environment prior to preterm birth. (bmj.com)
  • Testing of placental tissue specimens by Zika virus reverse-transcription polymerase chain reaction (RT-PCR) is conducted at CDC's Infectious Diseases Pathology Branch (IDPB). (cdc.gov)
  • Data on the placental pathology could be useful in the neurodevelopmental follow-up of VLBW infants. (unipv.it)
  • Hematologic effects of placental pathology on very low birthweight inf" by Kelly J. Zook, MD, Amy B. Mackley, RNC et al. (jefferson.edu)
  • Placental pathology was reviewed for the presence of placental infarction and vasculopathy. (jefferson.edu)
  • Additionally, in recent years, it has been revealed that there is a clear relationship between placental pathology and intrauterine growth restriction/preeclampsia [ 13 ]. (hindawi.com)
  • While feto-placental ratio was higher with increased severity of the disease, the mean weight was less. (hindawi.com)
  • Although about 20 cases of PTU induced hepatic damage were reported in the medical literature, this is, as far as we know, the first description of neonatal liver injury probably caused by placental transfer of this drug. (nih.gov)
  • There was no association of placental infarction or vasculopathy with neonatal neutropenia and thrombocytopenia. (jefferson.edu)
  • At natural (normal) birth with natural closure of the umbilical vessels (no cord clamp used), neonatal asphyxia is avoided because placental oxygenation continues - the cord pulsates - until pulmonary oxygenation is established. (natural-parenting.com)
  • She has revised her practice's guidelines for the care of infants with Neonatal Abstinence Syndrome and is leading a quality improvement initiative at John Muir to implement these changes. (nastoolkit.org)
  • Because the care of premature babies is so different from that of full-term infants, preemies are usually placed in a neonatal intensive care unit (NICU) after delivery. (kidshealth.org)
  • Discussion The intrauterine growth restriction in newborn infants with CHD may represent an adaptive mechanism to cope with the compromised perfusion caused by the congenital cardiac anomaly. (bmj.com)
  • Methods: This is a cohort observational study comprising 595 VLBW infants during 2007 to 2015. (unipv.it)
  • OR = 0.37, 95% CI = 0.22 to 0.62) were also the only placental lesions that were independent predictors of a lower rate of intact survival in stepwise analysis for prognostic factors of the entire cohort. (unipv.it)
  • STUDY DESIGN: Retrospective cohort study of infants with birthweight (jefferson.edu)
  • The project involved improving the accuracy and precision of modeling the effects of prenatal alcohol exposure on placental gene expression using a longitudinal cohort study from Cape Town, South Africa. (harvard.edu)
  • In mild or severe preeclampsia/eclampsia, placentas had significant histological signs of ischaemia and degree of placental involvement by infarction is inversely proportional to fetal birth weight. (hindawi.com)
  • However, most of the studies so far on placental changes in preeclampsia and eclampsia were done on Caucasians and African blacks living in the western countries [ 11 , 14 - 18 ]. (hindawi.com)
  • Preeclampsia, gestational diabetes , placental problems, and fetal growth problems are more likely with multiple pregnancies. (kidshealth.org)
  • In newborn infants, the apparent half-lives of acebutolol and diacetolol averaged 10.1 to 15.6 hours and 19.8 hours, respectively. (drugs.com)
  • Results Newborn infants with CHD were significantly shorter and had lower birth weight and smaller head size compared to normal newborns. (bmj.com)
  • Only 17 women had malaria ( Plasmodium falciparum ), 6 with peripheral parasitaemia and 11 with both peripheral parasitaemia and placental malaria. (who.int)
  • This article presents compelling evidence that autism and related childhood disorders can result from brain damage caused by birth asphyxia - more specifically due to interruption of placental oxygenation at birth by premature umbilical cord clamping. (natural-parenting.com)
  • The serotonin receptor, HTR2A, exhibits placental expression and function and can be controlled through DNA methylation. (nih.gov)
  • Controlling for confounding variables, HTR2A methylation was negatively associated with infant quality of movement (p = 0.05) and positively associated with infant attention (p = 0.0001). (nih.gov)
  • In newborn preterm infants, AA requirements estimated from third trimester fetal growth are high. (bmj.com)
  • As a consequence of my research in infants with severe congenital heart defects, I have begun exploring fetal research. (upenn.edu)
  • I am currently the only neurologist to perform Fetal Neurology consults to optimize the care for infants with congenital malformations. (upenn.edu)
  • Infants with neutropenia and thrombocytopenia did not have an increased occurrence of placental infarction or maternal vasculopathy but were more likely to be of small gestational age (SGA) and of lower gestational age compared with infants without neutropenia or thrombocytopenia. (jefferson.edu)
  • After multivariable analysis, gestational age and SGA remained associated with both neutropenia and thrombocytopenia whereas placental infarction and vasculopathy did not remain in the models. (jefferson.edu)
  • Degree of placental infarction was correlated with the fetal birth weight. (hindawi.com)
  • The exposures were divided into high and low placental-transfer categories. (medscape.com)
  • There, I analyzed placental genomic and epigenomic data to understanding how molecular traits shape an infant's disease susceptibility and response to environmental exposures. (harvard.edu)
  • To assess the proportion of neonates who did not receive a vitamin K injection in 2013, records of a random sample of infants born during January-October 2013 at each of three Nashville area hospitals and at four major Tennessee nonhospital birthing centers were reviewed. (cdc.gov)
  • At the Nashville hospital with the highest proportion of neonates not administered vitamin K, 3.4% of 3,080 infants discharged from the newborn nursery received no vitamin K injection. (cdc.gov)
  • Ambient PAH exposure, as well as that from tobacco smoke, has been shown to reduce birthweight and increase the risk for small for gestational age infants. (bcm.edu)
  • The findings detail changes in antibodies, immune cell types and inflammatory markers in maternal blood, umbilical cord blood and placental tissues. (nih.gov)
  • cord blood and infant liver reserve levels of vitamin K are substantially below adult levels ( 1,2 ). (cdc.gov)
  • A cord smear was smaller than average at birth was nearly 3 prepared from the blood of the umbilical times that of infants estimated to be normal stump. (who.int)
  • In other words, infant anemia and autism are both caused by immediate cord clamping - the anemia by loss of blood volume and the autism by asphyxia. (natural-parenting.com)
  • OR = 0.38, 95% CI = 0.22 to 0.62) were associated with lower rates of infant survival with normal neurodevelopmental outcome. (unipv.it)
  • Placental epigenetic changes have been associated with antenatal depression and stress. (nih.gov)
  • These results illustrate the potential of milk- and wheat-derived peptides to exert antioxidant and epigenetic changes that may be particularly important during the postnatal transition from placental to GI nutrition. (saratoga.com)
  • Our experimental data from a mouse model indicates reduction in placental weights and surface area along with alteration of syncytialization pathways following ZEN exposure. (nih.gov)
  • The birth weights of infants remained similar between groups - most had normal weights. (nih.gov)
  • Their placental weights were significantly decreased compared to those for normal newborns. (bmj.com)
  • Ballantyne also noted that most dysmature infants had above average height and weight though some opined that the weight must be below average since there is reduced subcutaneous fat. (alleydog.com)
  • 36 weeks) infants with CHD {(cyanotic (n = 8) and acyanotic (n = 41)} diagnosed clinically and by echocardiography and compared these data with those for randomly selected normal FT newborns (n = 104). (bmj.com)
  • Conclusion In this study CHD was associated with significant affection of birth weight, length and head circumference and lower placental weight compared to normal newborns. (bmj.com)
  • Current sources indicate that dysmaturity or "postmaturity" is a syndrome among newborns which is caused by placental problems. (alleydog.com)
  • Because of the relatively extensive excretion of acebutolol and its active metabolite diacetolol into breastmilk and some possible reports of adverse reactions in breastfed infants, other agents are preferred, especially while nursing a newborn or preterm infant. (drugs.com)
  • One mother reported no adverse effects in her breastfed infant (age unstated) during acebutolol use. (drugs.com)
  • It is possible that the late postpartum adverse effects in the first infant were caused by acebutolol and diacetolol in breastmilk, but no measurements of infant plasma drug levels were made. (drugs.com)
  • The relative risk for developing late VKDB has been estimated at 81 times greater among infants who do not receive intramuscular vitamin K than in infants who do receive it ( 4 ). (cdc.gov)
  • She is actively involved in hospital-wide and county-wide opioid use reduction initiatives, specifically outcome improvement for mother/infant dyads with a history of substance use and exposure. (nastoolkit.org)
  • Cochrane Abstracts , Evidence Central , evidence.unboundmedicine.com/evidence/view/Cochrane/434726/all/Biochemical_tests_of_placental_function_versus_ultrasound_assessment_of_fetal_size_for_stillbirth_and_small‐for‐gestational‐age_infants. (unboundmedicine.com)
  • However, this restricted growth can pose a risk for postnatal development in these infants. (bmj.com)
  • Comoderator Gabriela Riemekasten, MD, director of the clinic for rheumatology and clinical immunology at University Hospital in Lübeck, Germany, told Medscape Medical News that she was surprised to see that more women received high than low placental-transfer drugs. (medscape.com)
  • For asymptomatic pregnant women who have recent possible Zika virus exposure but without ongoing possible exposure, similar to the updated recommendations for testing of non-tissue clinical specimens (e.g., serum and urine), testing of placental tissues is not routinely recommended. (cdc.gov)
  • Additional clinical and epidemiologic information may be requested, see Collecting and Submitting Placental and Fetal Tissue Specimens for Zika Virus Testing for minimum required information for pre-approval. (cdc.gov)
  • My clinical expertise is in the neurological care for children who are critically ill infants and children. (upenn.edu)
  • Researchers describe unique maternal, fetal, and placental immune responses among pregnant women with COVID-19 in a study led by NIH's Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD). (nih.gov)
  • CDC maintains a Zika consultation service available to health care providers and health departments regarding management of pregnant women and infants with possible Zika virus. (cdc.gov)
  • Study ​ ​The research team studied 2291 pregnant women who delivered a single infant between September 1996 and January 2000. (confectionerynews.com)
  • Infants born very preterm represent a nutritional emergency due to interruption in placental supply of essential macronutrients and micronutrients. (bmj.com)
  • Her infant had serum levels of acebutolol and diacetolol of 244 mcg/L and 594 mcg/L, respectively, on day 1 of life which decreased to 40 and 221 mcg/L on day 4 of life when breastfeeding was begun. (drugs.com)
  • Therefore, the potential long-term effects of this inflammatory process on infants requires further study. (nih.gov)
  • However, the inflammatory mediators influencing placental responses during infections are also expressed during homeostatic, healthy conditions. (news-medical.net)
  • A cross-sectional analytical study of placental pathologies in preeclamptic/eclamptic patients was performed in a blinded pattern and compared with matched normal controls. (hindawi.com)
  • For every pound of placental tissue, there is approximately 1 gram of microbial DNA," said lead study author Dr. Kjersti Aagaard, an obstetrician-gynecologist and maternal-fetal medicine specialist at the Baylor College of Medicine and Texas Children's Hospital in Houston. (livescience.com)
  • The researchers analyzed the genomes of the bacteria in 320 placentas, in the first study to focus on all the genomes in the placental microbiome. (livescience.com)
  • Oddly, the placental microbiome is most similar to the microbial community found in the mouth, according to the study. (livescience.com)
  • Ribonucleic acid (RNA) sequencing data from 42 samples of placental villi obtained from the GUSTO study were used to identify the gene co-expression module related to inflammation upregulated in Hofbauer cells, for which a weighted correlation network analysis was employed. (news-medical.net)
  • Risk of stillbirth and infant deaths after assisted reproductive technology: a Nordic study from the CoNARTaS group. (uib.no)
  • Introduction The heart-placental axis utilises many common molecules and genes and reflects intimate and synergistic growth of both organs. (bmj.com)
  • Anti-TNF monoclonal immunoglobulins, such as infliximab (Remicade and biosimilars), adalimumab (Humira and biosimilars), and golimumab (Simponi) have the highest placental transfer, reaching higher levels in fetal circulation than in maternal circulation, she noted. (medscape.com)
  • During critical periods of organogenesis (i.e., the 6-week period that follows the establishment of the placental circulation). (cdc.gov)
  • Along with other methylxanthines in chocolate it may, for instance, improve placental circulation. (confectionerynews.com)
  • Six of 10 loci reside in the EMID2 gene and were hypomethylated in the 16 high-risk profile infants' placentas. (nih.gov)
  • The histological changes in preeclamptic/eclamptic placentas include infarcts, increased syncytial knots, hypovascularity of the villi, cytotrophoblastic proliferation, thickening of the trophoblastic membrane, obliterative enlarged endothelial cells in the fetal capillaries, and atherosis of the spiral arteries in the placental bed [ 11 ]. (hindawi.com)