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  • Therapeutics Development
  • It also reviews key players involved in Complement C5 (C3 And PZP Like Alpha 2 Macroglobulin Domain Containing Protein 4 or C5) targeted therapeutics development with respective active and dormant or discontinued projects.The report is built using data and information sourced from proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources. (medindia.net)
  • It also reviews key players involved in Nuclear Factor Erythroid 2 Related Factor 2 HEBP1 or Nuclear Factor Erythroid Derived 2 Like 2 or NFE2L2 targeted therapeutics development with respective active and dormant or discontinued projects. (bioportfolio.com)
  • It also reviews key players involved in Neutrophil Elastase (Bone Marrow Serine Protease or Elastase 2 or Medullasin or PMN Elastase or Human Leukocyte Elastase or ELANE or EC 3.4.21.37) targeted therapeutics development with respective active and dormant or discontinued projects. (reportsnreports.com)
  • 2017
  • The latest report Nuclear Factor Erythroid 2 Related Factor 2 Pipeline Review, H1 2017, outlays comprehensive information on the Nuclear Factor Erythroid 2 Related Factor 2 HEBP1 or Nuclear Factor Erythroid Derived 2 Like 2 or NFE2L2 targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action MoA, route of administration RoA and molecule type. (bioportfolio.com)
  • Acute
  • Currently, Stealth is enrolling a multinational Phase II cardiac clinical study with Bendavia focused on ischemia reperfusion and microvascular injuries including the extent of "no-reflow" for patients experiencing acute ST segment elevation myocardial infarction (STEMI). (stealthbt.com)
  • responses
  • Bilateral renal pedicle clamping is commonly used to induce IR-AKI, but differences between effective clamp pressures and/or renal responses to ischemia between kidneys often lead to more variable results. (jove.com)
  • research
  • In this review we discuss pathways and processes being targeted in cancer, and speculate why these cancer targets should be on the minds of the cardiovascular clinical and research community. (ahajournals.org)
  • gain
  • Functional (Non Ulcer) Dyspepsia (Gastrointestinal) pipeline guide helps in identifying and tracking emerging players in the market and their portfolios, enhances decision making capabilities and helps to create effective counter strategies to gain competitive advantage. (htfmarketreport.com)
  • heart
  • The experience with trastuzumab and tyrosine kinase inhibitors outlined by others in this review series highlights how very well-designed targeted therapeutics can have untoward effects on the heart because of poorly understood or previously unknown roles of these same targets in the heart. (ahajournals.org)
  • model
  • We have developed a cell culture model to simulate hypothermic preservation and reperfusion in lung transplantation. (163.com)
  • guide
  • Note: Certain content / sections in the pipeline guide may be removed or altered based on the availability and relevance of data. (medindia.net)
  • The pipeline guide evaluates Functional (Non Ulcer) Dyspepsia (Gastrointestinal) therapeutics based on mechanism of action (MoA), drug target, route of administration (RoA) and molecule type. (htfmarketreport.com)
  • The pipeline guide evaluates Myocardial Ischemia (Cardiovascular) therapeutics based on mechanism of action (MoA), drug target, route of administration (RoA) and molecule type. (marketresearch.com)
  • latest
  • Drug profiles featured in the report undergoes periodic review following a stringent set of processes to ensure that all the profiles are updated with the latest set of information. (getnews.info)
  • factors
  • The factors that may increase the risk of developing myocardial ischemia include tobacco, diabetes, high blood pressure, high blood cholesterol or triglyceride levels, lack of physical activity, obesity and family history. (marketresearch.com)
  • target
  • C5a is also a potent chemokine which stimulates the locomotion of polymorphonuclear leukocytes and directs their migration toward sites of inflammation.Complement C5 (C3 And PZP Like Alpha 2 Macroglobulin Domain Containing Protein 4 or C5) pipeline Target constitutes close to 31 molecules. (medindia.net)
  • Nuclear Factor Erythroid 2 Related Factor 2 HEBP1 or Nuclear Factor Erythroid Derived 2 Like 2 or NFE2L2 pipeline Target constitutes close to 36 molecules. (bioportfolio.com)
  • Neutrophil Elastase (Bone Marrow Serine Protease or Elastase 2 or Medullasin or PMN Elastase or Human Leukocyte Elastase or ELANE or EC 3.4.21.37) pipeline Target constitutes close to 11 molecules. (reportsnreports.com)
  • Stealth has a rich and promising pipeline of preclinical and clinical compounds from a unique class of short peptides (500-700 Daltons each) that target mitochondria. (stealthbt.com)