• Pimozide (sold under the brand name Orap) is an antipsychotic drug of the diphenylbutylpiperidine class. (wikipedia.org)
  • Pimozide is based on the brand-name version Orap, which is no longer available. (optum.com)
  • Orap (pimozide) works by changing the actions of chemicals in the brain. (qualitydrugstorenow24.com)
  • Do you take pimozide (Orap)? (medscape.com)
  • Pimozide is an antipsychotic medication. (health32.com)
  • Whatever the moment, now you buy pimozide atypical antipsychotic. (adventist.singles)
  • Pimozide is a conventional antipsychotic of the diphenylbutylpiperidine class that has been clinically used for over 30 years. (ox.ac.uk)
  • Co-administration of the following drugs with ketoconazole is contraindicated: dofetilide, quinidine, pimozide, cisapride. (nih.gov)
  • A 2013 systematic review compared pimozide with other antipsychotics for schizophrenia or related psychoses: It is contraindicated in individuals with either acquired, congenital or a family history of QT interval prolongation. (wikipedia.org)
  • Similarly to other typical antipsychotics pimozide has a high affinity for the dopamine D2 receptor and this likely results in its sexual (due to prolactin hypersecretion) and extrapyramidal side effects as well as its therapeutic efficacy against the positive symptoms of schizophrenia. (wikipedia.org)
  • Pimozide belongs to the class of medications called antipsychotics. (pocketpills.com)
  • At 0.1 microM and 0.5 microM ketoconazole, the formation of DHPBI from 10 microM pimozide was inhibited by 32% and 62%, respectively. (nih.gov)
  • In 1985 pimozide was approved by the FDA for marketing as an orphan drug for the treatment of Tourette's syndrome. (wikipedia.org)
  • Pimozide is often coprescribed with serotonin reuptake inhibitor (SSRI) antidepressants to treat depression in patients with Tourette's syndrome. (nih.gov)
  • Pimozide is used to suppress the motor and phonic tics associated with Tourette's disorder. (health32.com)
  • A dangerous interaction, possibly resulting in irregular heartbeats and/or death may occur if pimozide is taken with any of the medicines listed above. (health32.com)
  • You may not be able to take pimozide, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above. (health32.com)
  • In human liver microsomes (HLMs), the inhibition of the primary route of pimozide metabolism, N-dealkylation to 1,3-dihydro-1-(4-piperidinyl)-2H-benzimidazol-2-one (DHPBI), by four SSRIs (fluoxetine, sertraline, paroxetine, and fluvoxamine) and azithromycin was tested. (nih.gov)
  • Azithromycin had negligible effect on pimozide (10 microM) N-dealkylation (19% at 100 microM azithromycin). (nih.gov)
  • These values are least 100-fold higher than the expected plasma concentrations after the usual daily doses of the SSRIs and azithromycin, suggesting that coadministration of SSRIs and azithromycin are unlikely to markedly diminish the elimination of pimozide in patients. (nih.gov)
  • Pimozide may also be used for purposes other than those listed in this medication guide. (health32.com)
  • Pimozide oral tablet is a generic medication that's prescribed to reduce involuntary tics of Tourette syndrome. (optum.com)
  • If you're taking pimozide long term, your doctor may suggest a 90-day supply of the medication. (optum.com)
  • Pimozide is a generic medication. (optum.com)
  • Pimozide is used in its oral preparation in schizophrenia and chronic psychosis (on-label indications in Europe only), Tourette syndrome, and resistant tics (Europe, United States and Canada). (wikipedia.org)
  • It is also contraindicated in individuals being cotreated with selective serotonin reuptake inhibitors (SSRI) or in those with a known hypersensitivity to pimozide or other diphenylbutyl-piperidine derivatives. (wikipedia.org)
  • Pimozide, which selectively blocks dopamine type-2 receptors, was the drug first reported to be useful in the condition, and several series indicated a good response in most patients who accepted it. (cdc.gov)
  • However, patients who experience negative side-effects with the first line medications are typically given pimozide. (wikipedia.org)
  • Like other medications, the cost of pimozide can vary. (optum.com)
  • You could get Pimozide delivered at your doorstep from us in Canada if you ordered prescription medications with a valid prescription. (pocketpills.com)
  • At 10 microM paroxetine, sertraline, fluoxetine, or fluvoxamine, the formation of DHPBI from pimozide (10 microM) in HLMs was inhibited by an average (three HLMs) of 7%, 7.7%, 8%, and 16%, respectively, whereas this inhibition did not exceed 55% at the maximum concentrations (100 microM) of the SSRIs tested. (nih.gov)
  • In addition, the possibility that these drugs could alter pimozide disposition through effects on transport proteins or via promoter repression cannot be ruled out. (nih.gov)
  • Pimozide is in the FDA pregnancy category C. This means that it is not known whether pimozide will be harmful to an unborn baby. (health32.com)
  • It can be harmful for people to take Pimozide if their doctor has not prescribed it. (pocketpills.com)
  • If you have prescription drug insurance, your insurance company may require prior authorization before it covers the cost of pimozide. (optum.com)
  • In this case, your doctor will communicate with your insurance company regarding your prescription for pimozide. (optum.com)
  • Pimozide can interact with grapefruit products, and the interaction may have dangerous effects. (health32.com)
  • In one case a series of 33 patients with delusional parasitosis (median age, 60 years), pimozide was prescribed for 24 patients, 18 of whom took the drug. (wikipedia.org)
  • Of those patients receiving pimozide, 61% (11/18) experienced improvement in or full remission of symptoms. (wikipedia.org)
  • The use of pimozide for the treatment of delusional parasitosis is based primarily on data from case series/reports that demonstrate some efficacy in the majority of patients. (wikipedia.org)
  • These effects in adipogenesis by pimozide may help to explain the weight gain that is frequently observed in patients treated with pimozide. (ox.ac.uk)
  • There have been numerous studies showing pimozide can be used successfully to treat delusional parasitosis and traditionally was the drug of choice. (wikipedia.org)
  • www.drugguide.com/ddo/view/Davis-Drug-Guide/51612/all/pimozide. (drugguide.com)
  • Your doctor may have suggested Pimozide for conditions other than those listed in these drug information articles. (pocketpills.com)
  • Pimozide may be available under multiple brand names and/or in several different forms. (pocketpills.com)
  • Very common (>10% frequency) side effects include: Akinesia Constipation Dizziness Dry mouth Hyperhidrosis Nocturia Somnolence Speech disorder Pimozide overdose presents with severe extrapyramidal symptoms, hypotension, sedation, QT interval prolongation and ventricular arrhythmias including torsades de pointes. (wikipedia.org)
  • The side effects listed below are not experienced by everyone who takes Pimozide. (pocketpills.com)
  • If you are concerned about side effects, discuss the risks and benefits of Pimozide with your doctor. (pocketpills.com)
  • If you'd like more information about pimozide, including its uses, talk with your doctor or pharmacist. (optum.com)
  • To find out how much pimozide costs, ask your doctor, pharmacist, or insurance provider. (optum.com)
  • If you have not discussed this with your doctor or are not sure why you are taking Pimozide, speak to your doctor. (pocketpills.com)
  • Do not stop taking Pimozide without consulting your doctor. (pocketpills.com)
  • Pimozide has been used in the treatment of delusional disorder and paranoid personality disorder. (wikipedia.org)
  • Gastric lavage, establishment of a patent airway and, if necessary, mechanically assisted respiration is the recommended treatment for pimozide overdose. (wikipedia.org)
  • Do not consume grapefruit or grapefruit juice during treatment with pimozide. (health32.com)
  • How to get Pimozide in Canada for free? (pocketpills.com)
  • You can get Pimozide for free in Canada if your health insurance provider covers it fully. (pocketpills.com)
  • Pimozide attenuates free feeding. (bvsalud.org)
  • The cost of pimozide with or without insurance can depend on several factors. (optum.com)
  • Read on to learn about pimozide and cost. (optum.com)
  • How Much is Shipping Cost for Pimozide in Canada? (pocketpills.com)
  • Shipping cost for Pimozide to you in Canada is zero. (pocketpills.com)
  • Any specific brand name of Pimozide may not be available in all of the forms or approved for all of the conditions discussed here. (pocketpills.com)
  • As well, some forms of Pimozide may not be used for all of the conditions discussed here. (pocketpills.com)
  • What is the most important information I should know about Pimozide? (health32.com)
  • To find out what you'd pay using savings coupons, read the "Coupons for pimozide" section. (optum.com)
  • Cardiac monitoring should be continued for at least 4 days due to the long half-life of pimozide. (wikipedia.org)
  • What should I discuss with my healthcare provider before taking Pimozide? (health32.com)