Pi3k functional tyrosine kinase domain src homology 3 domain. Medical search. Frequent questions

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Anatomy18

Cell Line 3T3 Cells Cells, Cultured Cell Line, Tumor Tumor Cells, Cultured Cell Membrane COS Cells K562 Cells HeLa Cells Cytoplasm CHO Cells Jurkat Cells Fibroblasts Cell Nucleus Cell Line, Transformed NIH 3T3 Cells HEK293 Cells PC12 Cells

Organisms8

Escherichia coli Cricetinae Cercopithecus aethiops Saccharomyces cerevisiae Mice, Knockout Cattle Mice, Inbred C57BL Chickens

Diseases5

Pain Insensitivity, Congenital Cell Transformation, Neoplastic Hypohidrosis Leukemia, Myelogenous, Chronic, BCR-ABL Positive Lung Neoplasms

Chemicals and Drugs139

Tyrosine Protein-Tyrosine Kinases Receptor Protein-Tyrosine Kinases src-Family Kinases Phosphatidylinositol 3-Kinases Protein Kinase Inhibitors Phosphotyrosine Proto-Oncogene Proteins Receptor, Epidermal Growth Factor Recombinant Fusion Proteins Protein Tyrosine Phosphatases Protein Kinases Proto-Oncogene Proteins c-abl Protein-Serine-Threonine Kinases Recombinant Proteins Adaptor Proteins, Signal Transducing Proto-Oncogene Proteins pp60(c-src)Phosphoproteins Intracellular Signaling Peptides and Proteins Pyrimidines fms-Like Tyrosine Kinase 3 Receptor, Insulin Protein Tyrosine Phosphatase, Non-Receptor Type 11 Calcium-Calmodulin-Dependent Protein Kinases Enzyme Inhibitors Protein Tyrosine Phosphatase, Non-Receptor Type 6 Proto-Oncogene Proteins c-fyn Lymphocyte Specific Protein Tyrosine Kinase p56(lck)DNA, Complementary DNA-Binding Proteins Benzamides DNA Primers Proto-Oncogene Proteins c-kit Piperazines Membrane Proteins RNA, Messenger Carrier Proteins GRB2 Adaptor Protein Proteins Janus Kinase 2 Quinazolines Ligands Proto-Oncogene Proteins c-ret Protein Kinase C DNA Receptor, trkA Mitogen-Activated Protein Kinases Phospholipase C gamma Mitogen-Activated Protein Kinase 1 Receptors, Fibroblast Growth Factor Fusion Proteins, bcr-abl Proto-Oncogene Proteins c-met Epidermal Growth Factor Isoenzymes Genistein Antineoplastic Agents Receptor, Fibroblast Growth Factor, Type 5 Proto-Oncogene Proteins c-akt Focal Adhesion Protein-Tyrosine Kinases Focal Adhesion Kinase 2 Transcription Factors Tyrosine 3-Monooxygenase Glutathione Transferase Mitogen-Activated Protein Kinase 3 Focal Adhesion Kinase 1 SH2 Domain-Containing Protein Tyrosine Phosphatases Phosphotransferases (Alcohol Group Acceptor)Cyclic AMP-Dependent Protein Kinases Receptors, Platelet-Derived Growth Factor Trans-Activators Receptor, Fibroblast Growth Factor, Type 1 Drosophila Proteins Peptides p38 Mitogen-Activated Protein Kinases Mitogen-Activated Protein Kinase Kinases Peptide Fragments Type C Phospholipases Oncogene Protein pp60(v-src)JNK Mitogen-Activated Protein Kinases p21-Activated Kinases Nuclear Proteins Receptors, Cell Surface Proto-Oncogene Proteins c-crk Shc Signaling Adaptor Proteins Calcium STAT5 Transcription Factor Milk Proteins Vanadates Serine Extracellular Signal-Regulated MAP Kinases Phosphopeptides Bacterial Proteins Nerve Tissue Proteins MAP Kinase Kinase Kinases Proto-Oncogene Proteins c-hck Phosphoric Monoester Hydrolases Receptors, Growth Factor Cytoskeletal Proteins Receptor, erbB-2 Adaptor Proteins, Vesicular Transport Enzyme Precursors Receptors, Nerve Growth Factor Tyrphostins Ribosomal Protein S6 Kinases Protein Isoforms Proto-Oncogene Proteins c-cbl Proline Actins ZAP-70 Protein-Tyrosine Kinase Adenosine Triphosphate Cell Cycle Proteins Quinones Morpholines Chromones Indoles Androstadienes 1-Phosphatidylinositol 4-Kinase Oncogene Proteins Nerve Growth Factors Lactams, Macrocyclic Cyclin-Dependent Kinases Phosphatidylinositol Phosphates Nucleoside-Phosphate Kinase GTPase-Activating Proteins RNA, Small Interfering Oncogene Proteins v-abl Benzoquinones CDC2 Protein Kinase Threonine MAP Kinase Kinase 1 Receptor, IGF Type 1 Macromolecular Substances Guanylate Kinase Microfilament Proteins Proto-Oncogene Proteins c-yes Antibodies, Monoclonal Oncogene Proteins, Fusion eIF-2 Kinase Receptors, Antigen, B-Cell

Analytical, Diagnostic and Therapeutic Techniques and Equipment20

Transfection Cloning, Molecular Sequence Alignment Mutagenesis, Site-Directed Models, Molecular Crystallography, X-Ray Blotting, Western DNA Mutational Analysis Precipitin Tests Immunoblotting Amino Acid Substitution Models, Biological Two-Hybrid System Techniques Polymerase Chain Reaction Electrophoresis, Polyacrylamide Gel Microscopy, Fluorescence Immunoprecipitation Peptide Mapping Immunohistochemistry Reverse Transcriptase Polymerase Chain Reaction

Phenomena and Processes62

src Homology Domains Phosphorylation Signal Transduction Amino Acid Sequence Sequence Homology, Amino Acid Mutation Protein Binding Base Sequence Protein Structure, Tertiary Binding Sites Enzyme Activation Transfection MAP Kinase Signaling System Kinetics Protein Conformation Structure-Activity Relationship Amino Acid Motifs Point Mutation Sequence Deletion Protein Interaction Domains and Motifs Dimerization Sequence Homology, Nucleic Acid Amino Acid Substitution Protein Structure, Secondary Cell Division Mutation, Missense Gene Expression Genes, erbB-1 Conserved Sequence Protein Transport Genes, src Substrate Specificity Exons Mutagenesis Transcription, Genetic Apoptosis Drug Resistance, Neoplasm Plasmids Gene Expression Regulation Phenotype Time Factors Cell Adhesion Protein Processing, Post-Translational Dose-Response Relationship, Drug Proto-Oncogenes Molecular Weight Cell Movement Cell Proliferation Catalysis Down-Regulation Oncogenes Gene Expression Regulation, Enzymologic PDZ Domains Catalytic Domain Cell Differentiation Cell Survival Structural Homology, Protein Protein Multimerization Transcriptional Activation Promoter Regions, Genetic Protein Structure, Quaternary Protein Folding

Disciplines and Occupations1

Immunohistochemistry

Technology, Industry, Agriculture1

Information Science3

Molecular Sequence Data Amino Acid Sequence Base Sequence

Anatomy Organisms Diseases Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Technology, Industry, Agriculture Information Science

src Homology Domains Tyrosine Protein-Tyrosine Kinases Phosphorylation Receptor Protein-Tyrosine Kinases Molecular Sequence Data Signal Transduction Amino Acid Sequence Sequence Homology, Amino Acid src-Family Kinases Phosphatidylinositol 3-Kinases Mutation Protein Kinase Inhibitors Phosphotyrosine Protein Binding Base Sequence Proto-Oncogene Proteins Receptor, Epidermal Growth Factor Protein Structure, Tertiary Recombinant Fusion Proteins Binding Sites Cell Line Enzyme Activation Transfection Cloning, Molecular Protein Tyrosine Phosphatases Protein Kinases Proto-Oncogene Proteins c-abl Protein-Serine-Threonine Kinases Recombinant Proteins Adaptor Proteins, Signal Transducing Proto-Oncogene Proteins pp60(c-src)Phosphoproteins Sequence Alignment 3T3 Cells MAP Kinase Signaling System Mutagenesis, Site-Directed Models, Molecular Intracellular Signaling Peptides and Proteins Pyrimidines fms-Like Tyrosine Kinase 3 Receptor, Insulin Kinetics Protein Conformation Cells, Cultured Protein Tyrosine Phosphatase, Non-Receptor Type 11 Calcium-Calmodulin-Dependent Protein Kinases Crystallography, X-Ray Enzyme Inhibitors Protein Tyrosine Phosphatase, Non-Receptor Type 6 Proto-Oncogene Proteins c-fyn Lymphocyte Specific Protein Tyrosine Kinase p56(lck)Structure-Activity Relationship DNA, Complementary Amino Acid Motifs DNA-Binding Proteins Benzamides Point Mutation Sequence Deletion DNA Primers Proto-Oncogene Proteins c-kit Protein Interaction Domains and Motifs Blotting, Western Piperazines Membrane Proteins RNA, Messenger Dimerization Carrier Proteins DNA Mutational Analysis GRB2 Adaptor Protein Precipitin Tests Proteins Pain Insensitivity, Congenital Janus Kinase 2 Sequence Homology, Nucleic Acid Quinazolines Immunoblotting Cell Line, Tumor Ligands Proto-Oncogene Proteins c-ret Tumor Cells, Cultured Protein Kinase C Amino Acid Substitution Cell Membrane DNA Receptor, trkA Mitogen-Activated Protein Kinases Protein Structure, Secondary Phospholipase C gamma Mitogen-Activated Protein Kinase 1 Receptors, Fibroblast Growth Factor Cell Division Fusion Proteins, bcr-abl Proto-Oncogene Proteins c-met Epidermal Growth Factor Cell Transformation, Neoplastic Isoenzymes COS Cells Genistein Antineoplastic Agents

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