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Growth HormoneHuman Growth HormoneReceptors, SomatotropinPhysiologyHormonesGrowth Hormone-Releasing HormoneThyroid HormonesFollicle Stimulating HormoneInsulin-Like Growth Factor IGrowth DisordersProlactinLuteinizing HormoneDwarfism, PituitaryPituitary GlandHypophysectomyGonadotropin-Releasing HormoneParathyroid HormoneGonadal Steroid HormonesPituitary HormonesAcromegalyPeptide HormonesAdrenocorticotropic HormoneReceptors, Thyroid HormoneReceptors, GhrelinPituitary Gland, AnteriorTriiodothyronineGhrelinPlacental LactogenPituitary NeoplasmsHypopituitarismDwarfismHormone Replacement TherapyPlacental HormonesHydrocortisoneThyroxinePituitary Hormones, AnteriorSomatostatinInsulinRNA, MessengerBody HeightThyrotropinReceptors, Pituitary Hormone-Regulating HormoneEstradiolTestosteroneRadioimmunoassayGrowthJuvenile HormonesMolecular Sequence DataLiverTurner SyndromeCattleBody WeightTime FactorsCorticotropin-Releasing HormoneBase SequenceGene Expression RegulationProgesteroneRecombinant ProteinsHypothalamusReceptors, ProlactinSomatomedinsPancreatic HormonesPregnancyInsulin-Like Growth Factor Binding Protein 3SheepHypothalamic HormonesSignal TransductionBlood GlucoseTranscription Factor Pit-1Age Determination by SkeletonGonadal HormonesPubertyHormone AntagonistsPituitary Hormone-Releasing HormonesSTAT5 Transcription FactorAnti-Mullerian HormoneThyrotropin-Releasing HormoneLaron SyndromeThyroid Hormone Receptors betaReceptors, NeuropeptidePituitary Function TestsDose-Response Relationship, DrugCell LineRats, Sprague-DawleySecretory RateAmino Acid SequenceEstrogensCells, CulturedOrgan SizeOvaryGastrointestinal HormonesHypothyroidismSex CharacteristicsGlucagonTranscription, GeneticOvariectomyKineticsBody CompositionSermorelinHypothalamo-Hypophyseal System
MetabolismInsulinSecretionPlant PhysiologyHuman growthPituitary HormonesProlactinSomatostatinAnatomyThyrotropin-releasiIntegrative PhysiologyDeficiencyJournal of PhysiologyProfessor of PhysiologySomatotropinGHRHEndocrinologyProteinsRegulatePubertyTestosteronePeptidesReceptorRecombinantReceptorsStimulateCortisolSteroidsNutritionEndocrine glandHomologousRegulationPathophysiologyRegulatesSecretagoguesReproductiveGhrelinHumansMetabolicSubstancesGHRDPharmacologyEpidermal growthChorionicBloodstreamOvarianBehavior
Metabolism13
  • Human growth hormone (HGH) is necessary for growth, cell repair, and metabolism. (healthnews.com)
  • This is how the human growth hormone regulates metabolism to support normal growth. (healthnews.com)
  • Carbohydrates are broken down by the body to provide glucose, which is required for effective cell metabolism and growth hormone regulation. (healthnews.com)
  • Applied Physiology, Nutrition, and Metabolism (2019) 44 (2): 111. (aacrjournals.org)
  • Inheritance patterns in metabolism and growth in diallel crosses of Arabidopsis thaliana from a single growth habitat. (mpg.de)
  • GI physiology and metabolism, including the microbiome, short chain fatty acid (SCFA) metabolism and SCFA receptors in regulating gut hormone secretion, metabolism and islet biology. (uic.edu)
  • Assistant Professor, Department of Physiology and Biophysics (Adjunct member, Division of Endocrinology, Diabetes and Metabolism). (uic.edu)
  • Professor in Medicine, Division of Endocrinology, Diabetes and Metabolism (Adjunct member, Department of Physiology and Biophysics). (uic.edu)
  • The endocrine system works together with the nervous system to regulate growth, reproduction, and metabolism. (medindia.net)
  • Adrenal hormones help regulate the immune system, blood pressure, metabolism, and the body's salt and water balance. (medindia.net)
  • American Journal of Physiology: Endocrinology and Metabolism, 295(6 Pt 1), E937-E947. (phunkphenomenon.com)
  • American Journal of Physiology: Endocrinology and Metabolism, 280(3), E1781-1789. (phunkphenomenon.com)
  • The level of phosphorus is tightly regulated by three main hormones [parathyroid hormone (PTH), vitamin D and fibroblast growth factor-23 (FGF-23)], which affect the intestinal absorption and renal excretion of phosphorus and bone mineral metabolism. (medscape.com)
Insulin15
  • Recombinant insulin growth factor I in growth therapy. (medscape.com)
  • Insulin-like growth factor I (IGF-I) is the effector of growth induced by growth hormone (GH). (medscape.com)
  • The most critical of these proteins is the signal transducer and activator of transcription 5b (STAT5b), which couples GH binding to the activation of gene expression that leads to the intracellular effects of GH, including synthesis of IGF-I, insulin-like growth factor binding protein 3 (IGFBP3), and ALS. (medscape.com)
  • The authors searched public genome databases for viral peptide sequences that shared homology with human hormones, growth factors or cytokines and found 16 full-length sequences that encode homologues, including four insulin-like growth factor 1 (IGF1) peptides. (nature.com)
  • Synthetic viral IGF1 peptides bound to human and mouse insulin and to IGF1 receptors in vitro, stimulating downstream signalling and increasing glucose uptake and cell growth. (nature.com)
  • Plasma insulin-like growth factor-1 increased over the same period and then remained constant in both ration groups and was lower in feed-restricted versus standard ration fish from week 8 to week 30. (critfc.org)
  • Another interesting thing HGH does is promote the production of an insulin-growth factor that suppresses the body's insulin activity. (healthnews.com)
  • Insulin is a hormone that controls the blood glucose level. (healthnews.com)
  • Studies have shown that nutritional deprivation and malnutrition are associated with abnormal levels of growth hormone and insulin-like growth factors in the body. (healthnews.com)
  • Acromegaly is a severe disease characterized by hypersecretion of growth hormone (GH), which induces the synthesis of peripheral insulin-like growth factor 1 (IGF-1) after the closure of the epiphyseal bone. (scirp.org)
  • His laboratory was the first to show that growth hormone and insulin-like growth factor 1 (IGF1) are major players in the regulation of lifespan in the mammal. (eurekalert.org)
  • Now, insulin resistance is when your cells become less sensitive to insulin (Insulin is the hormone produced by the pancreas which is responsible for getting sugar out of the blood). (bodybuilding.com)
  • This, in turn, regulates your blood sugar, lowering the hormone which has been proven to inhibit fat loss and increase fat storage, insulin. (bodybuilding.com)
  • The relationship was investigated between baseline serum levels of total testosterone (T), free testosterone (FT), dehydroepiandrosterone sulfate (DHEAS), ESTRADIOL (E2), sex hormone-binding globulin (SHBG), insulin-like growth factor-1 (IGF-1) and cognitive functioning in 25 healthy older men (mean age 69.1 years). (rug.nl)
  • Which hormone (GH or IGF-1) increases tissue sensitivity to insulin? (flashcardmachine.com)
Secretion5
Plant Physiology1
Human growth14
Pituitary Hormones4
Prolactin4
Somatostatin3
Anatomy2
  • Develop an understanding of the normal anatomy, histology, physiology, biochemistry of each of the following endocrine glands. (massgeneral.org)
  • We will study the phylogeny, anatomy, physiology, and ecology of the major extinct and extant taxa of vertebrates and discuss how each group solves the problems of finding food, finding mates, and avoiding predators. (middlebury.edu)
Thyrotropin-releasi1
Integrative Physiology1
Deficiency5
  • A recombinant form of HGH called somatropin (INN) is used as a prescription drug to treat children's growth disorders and adult growth hormone deficiency. (wikipedia.org)
  • IGF-I deficiency can be the result of GH resistance or insensitivity due to genetic disorders of the GH receptor causing GH receptor deficiency (growth hormone receptor deficiency [GHRD], Laron syndrome) or postreceptor defects, including the principal transduction agent STAT5b, the IGF-I/IGFBP3 stabilizer acid labile subunit (ALS), the IGF-I gene, or the IGF-I receptor. (medscape.com)
  • HGH injections are approved to treat adults and children who have growth hormone deficiency, for people who are undergoing organ transplants, and for AIDS-related muscle wastingin adults. (paradiseessentials2020.com)
  • Taken legally through treatment-activated ER-alpha increases the expression of aromatase growth hormone deficiency and excess provide very visible testaments to the role of this hormone in normal physiology. (tattoorockparlour.com)
  • ALS deficiency has modest, at most, effect on growth, without any other phenotypic features. (medscape.com)
Journal of Physiology3
Professor of Physiology1
Somatotropin1
  • The names somatotropin (STH) or somatotropic hormone refer to the growth hormone produced naturally in animals and extracted from carcasses. (wikipedia.org)
GHRH1
  • In rare cases, the disease is associated with excessive production of GH-releasing hormone (GHRH), familial syndromes, including multiple endocrine neoplasia type 1, McCune-Albright syndrome, familial acromegaly, and Carney's syndrome. (scirp.org)
Endocrinology2
  • To investigate the growth and reproductive endocrinology of the post-spawn period, we sampled female rainbow trout over the 30 weeks following their first spawning. (critfc.org)
  • Bhasin is an internationally known translational investigator whose pioneering investigations in the field of androgen hormones such as testosterone have been notable for their bold study design, innovation and enduring impact in bringing resolution to controversial issues in reproductive endocrinology. (eurekalert.org)
Proteins2
  • Proteins and amino acids promote growth and provide cells and muscles energy to support life. (healthnews.com)
  • All this is controlled by hormones, genes and proteins so that the plant can function as an individual. (lu.se)
Regulate5
  • The involvement of stress and hormone signalling in outgrowth formation was supported by a global transcriptome analysis, which additionally revealed that TCP1, a transcription factor known to regulate leaf growth and symmetry, was downregulated in the outgrowth tissue. (whiterose.ac.uk)
  • The Nobel Prize in Physiology or Medicine is awarded for discoveries which are of fundamental importance for our understanding of the mechanisms which regulate cell and organ growth. (nobelprize.org)
  • This chapter describes the different parts of the female reproductive system: the organs involved in the process of reproduction, hormones that regulate a woman's body, the menstrual cycle, ovulation and pregnancy, the female's role in genetic division, birth control, sexually transmitted diseases and other diseases and disorders. (wikibooks.org)
  • Receptors inside cells interact with hormones that regulate gene function (eg, corticosteroids, vitamin D , thyroid hormone). (msdmanuals.com)
  • these hormones act in the periphery to regulate water balance, milk ejection, and uterine contraction. (msdmanuals.com)
Puberty3
  • Teens must eat a balanced diet to capitalize on their growth rates during puberty. (healthnews.com)
  • And both systems experience maturation of their reproductive organs, which become functional during puberty as a result of the gonads secreting sex hormones. (wikibooks.org)
  • Sexual development characteristics include small penis in childhood with normal growth with adolescence, delayed puberty, and normal fertility. (medscape.com)
Testosterone3
  • The term growth hormone has been incorrectly applied to refer to anabolic sex hormones in the European beef hormone controversy, which initially restricts the use of estradiol, progesterone, testosterone, zeranol, melengestrol acetate and trenbolone acetate. (wikipedia.org)
  • His landmark study demonstrated conclusively that testosterone increases muscle mass and strength in healthy men with normal levels of the hormone and that the hormone's anabolic effects are augmented by resistance exercise. (eurekalert.org)
  • When taken, testosterone is the hormone of choice for muscle-strengthening and strength training, hygetropin side effects. (paradiseessentials2020.com)
Peptides1
Receptor4
  • Furthermore, these variants circulate partially bound to a protein (growth hormone-binding protein, GHBP), which is the truncated part of the growth hormone receptor, and an acid-labile subunit (ALS). (wikipedia.org)
  • Growth failure due to heterozygous mutation of the type I IGF receptor is responsive to rhGH. (medscape.com)
  • 2011. The inhibitory control of oocyte maturation in the zebrafish: the role of the G-protein coupled estrogen receptor and epidermal growth factor. (uoguelph.ca)
  • Heterozygous IGF-I receptor mutations have no or mild-to-moderate effect on brain development, but they do result in intrauterine growth retardation. (medscape.com)
Recombinant1
  • The main growth hormone produced by recombinant DNA technology has the approved generic name (INN) somatropin and the brand name Humatrope, and is properly abbreviated rhGH in the scientific literature. (wikipedia.org)
Receptors1
  • Hormones bind selectively to receptors located inside or on the surface of target cells. (msdmanuals.com)
Stimulate3
Cortisol4
  • Cortisol and, even more so, adrenaline, are stimulating hormones and can keep us awake. (girlsgonestrong.com)
  • Like any hormone, cortisol has to be just right. (girlsgonestrong.com)
  • As our adrenal glands (source of both cortisol and adrenaline) work to keep our brain, heart, and everything else going throughout the night without a food supply coming in for energy, we employ these stress hormones to keep us tapped into our sugar stores. (girlsgonestrong.com)
  • Growth Hormone can lower cortisol production, which can be very good in hypercortisol stress states and Cushing's syndrome. (bio.net)
Steroids5
  • In addition, we are addressing the relevance of growth factors to ovarian physiology (IGFs, steroids, retinoids) by studying their actions and assessing of their sites of synthesis within the ovary and regulation of their production. (uoguelph.ca)
  • What Does Creatine Do For Me, muscle growth stories steroids? (phunkphenomenon.com)
  • It increases power production, muscle growth stories steroids. (phunkphenomenon.com)
  • While this may be a very generalised observation we can also take this to mean that if you take steroids your body is forced to use them, this can be in many different situations, such as training sessions or when your body's natural defenses are depleted, best time to take growth hormone injections. (paradiseessentials2020.com)
  • Anabolic steroids possession and have previously been vaccination were present in umbilical cord blood, indicating the order to maintain a more constant level of hormone in the system. (tattoorockparlour.com)
Nutrition3
  • The already compromised growth of children with GHRD may be further compromised by poor appetite or social circumstances limiting nutrition. (medscape.com)
  • Nutrition plays an important role in supporting growth and development. (healthnews.com)
  • The role nutrition plays in normal growth and development cannot be over-emphasized. (healthnews.com)
Endocrine gland1
  • Once in circulation, hormones affect function of the target tissues, which may be another endocrine gland or an end organ. (msdmanuals.com)
Homologous1
Regulation2
  • The pattern for growth and differentiation has long been established but the regulation of this development has remained unknown. (nobelprize.org)
  • It was only during the past 2-3 decades with the discovery of growth factors that our understanding of the regulation of cell's growth and differentiation has begun to be clarified. (nobelprize.org)
Pathophysiology1
Regulates1
  • These results demonstrate that a combination of natural alleles of OAK regulates growth and development through the integration of hormone and stress signals and highlight the importance of natural variation as a resource to discover the function of gene variants that are not present in the most studied accessions of A. thaliana. (whiterose.ac.uk)
Secretagogues1
  • Such is not a concern generally with the weaker but safer over-the-counter HGH secretagogues Growth hormone enhances thyroid physiology by increasing the conversion thyroxin (T4) into the more active tri-iodothyronine (T3). (bio.net)
Reproductive3
  • In iteroparous female salmonids, the growth and reproductive endocrine axes interact during the period after spawning. (critfc.org)
  • These results suggest that two phases occurred during the post-spawn period: recovery from spawning and restoration of energy reserves over weeks 0 to 8, followed by adjustment of the growth and reproductive endocrine axes to ration level over weeks 8 to 30. (critfc.org)
  • On going research focuses on the development of short term in vitro techniques through to whole animal test methods applicable in lab and field settings to evaluate both general reproductive physiology through to the effects seen following exposure to chemicals on reproductive physiology of fish. (uoguelph.ca)
Ghrelin1
  • Her research into the neurobiology of appetite aims to unravel neurobiological pathways that respond to orexigenic signals, such as the hormone, ghrelin, and that drive feeding behaviours, not only food intake but also food choice, food anticipation, food reward and food motivation. (gu.se)
Humans1
  • The laboratory will emphasize plant identification, various aspects of plant ecology and physiology, plant morphology, and plant use by humans. (middlebury.edu)
Metabolic2
  • Metabolic efficiency underpins performance trade-offs in growth of Arabidopsis thaliana. (mpg.de)
  • There is also concern with HGH enhancements effect on those already on hormone therapy for metabolic disorders such as diabetes, hypothyroidism, and Addison's syndrome. (bio.net)
Substances4
  • NGF and EGF were the first of many growth-regulating signal substances to be discovered and characterized. (nobelprize.org)
  • Today, we know that cells communicate with each other via signal substances, hormones. (nobelprize.org)
  • It has now become clear that many cell types synthesize signal substances or hormones which have their effects both on their cell of origin as well as on neighbouring cells. (nobelprize.org)
  • They did not know, however, the identity of the active substances, just as cancer researchers understood little of the unregulated growth of tumour cells. (nobelprize.org)
GHRD3
  • The only specific treatment available for patients with genetic disorders causing GH resistance with growth failure due to GHRD, STAT5b mutations, ALS mutations, or IGF1 gene mutation is rhIGF-I. (medscape.com)
  • IGF-I mutations differ from GHRD with severe mental retardation, sensorineural deafness, micrognathia, microcephaly, and intrauterine growth retardation. (medscape.com)
  • A 21-year-old woman and her 23-year-old brother with GHRD/Laron syndrome demonstrating variable effects on growth of the same mutation and the correlation with low levels of IGF-I in IGFBP3. (medscape.com)
Pharmacology1
  • honours) in Pharmacology and with a Ph.D. in Neuroendocrinology from the University of Cambridge in 1993, where she later became Senior Lecturer in Physiology. (gu.se)
Epidermal growth1
  • The pattern of cellular growth has long been known, but it is the Italian developmental biologist Rita Levi-Montalcini and the American biochemist Stanley Cohen with their discovery of nerve growth factor (NGF) and epidermal growth factor (EGF), respectively, who could show how the growth and differentiation of a cell is regulated. (nobelprize.org)
Chorionic1
  • growth hormone variant), are localized in the q22-24 region of chromosome 17 and are closely related to human chorionic somatomammotropin (also known as placental lactogen) genes. (wikipedia.org)
Bloodstream3
  • The level of a pituitary hormone may be high in the bloodstream if you have a pituitary tumor that is producing too much of that hormone. (medlineplus.gov)
  • The endocrine glands do not have any ducts and transfer hormones directly into the bloodstream. (medindia.net)
  • The endocrine system coordinates functioning between different organs through hormones, which are chemicals released into the bloodstream from specific types of cells within endocrine (ductless) glands. (msdmanuals.com)
Ovarian2
  • Fish are used as the experimental model for studies investigating how the actions of hormones, growth factors of ovarian origin and intracellular signal transduction pathways interact to coordinate ovarian growth and differentiation. (uoguelph.ca)
  • We study the control of growth, atresia and hormone biosynthetic capacity of zebrafish ovarian follicles during the period of oocyte maturation and at ovulation. (uoguelph.ca)
Behavior1
  • Physiology and Behavior, 80 (5), 589-594. (bvsalud.org)