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GlycerolAquaporin 1Aquaporin 5Aquaporin 3Aquaporin 4AquaporinsPermeabilityAquaporin 2Glycerol KinaseCell Membrane PermeabilityAquaporin 6Capillary PermeabilityWaterOsmosisMercuric ChlorideWater-Electrolyte BalanceGlycerophosphatesAquaglyceroporinsBiological TransportBlood Group AntigensIon ChannelsOsmotic PressureGlycerolphosphate DehydrogenaseBlood-Brain BarrierKidney Tubules, CollectingOsmolar ConcentrationTight JunctionsPropylene GlycolMolecular Sequence DataCell MembraneMannitolMembrane ProteinsDihydroxyacetoneCryoprotective AgentsKidney Concentrating AbilityAmino Acid SequencePlant TranspirationGlyceridesKineticsOocytesBody WaterXenopus laevisLactulosePlant ProteinsRats, Sprague-DawleyDiabetes Insipidus, NephrogenicMitochondrial Membrane Transport ProteinsTime FactorsBrain EdemaDentin PermeabilityUreaCalciumNeuromyelitis OpticaEvans BlueHydrogen-Ion ConcentrationPolyuriaGlucoseFreezingCells, CulturedModels, BiologicalSugar Alcohol DehydrogenasesOccludinIntestinal AbsorptionVasopressinsDiffusionSodiumRNA, MessengerBiological Transport, ActiveRats, WistarPhloretinImmunohistochemistryGlycerol-3-Phosphate Dehydrogenase (NAD+)Antidiuretic AgentsEthylene GlycolDehydrationMitochondrial SwellingLens, CrystallineSodium ChloridePlant RootsMonoglyceridesSucroseEscherichia coliMembrane PotentialsTulipaVapor PressureLipolysisMutationPulmonary EdemaKidneyEye ProteinsEpithelial CellsElectric ImpedanceMercury CompoundsMice, KnockoutHypertonic SolutionsDextransBlotting, WesternCistaceaePotassiumIntracellular Membranes
AQPsPlasma-membrane aquaporinProteinsPoreArabidopsisProcessesCellularImportant roleExpressionWaterTransportAnalysisPlantVitroRecentEvidenceProvideGrowthCellsAquaglyceroporinsMembraneAtPIP1NicotianaPermeableProteinRolesHomeostasisPoresHydrationBiosynthesisKaldenhoffVivoTargetsConductanceClinicalHumanPlantsFunctionsWater channelFoundCellStopped-flowGroupType
AQPs10
  • This review focuses on emerging topics encompassing the functional involvement of aquaporin channel proteins (AQPs) and membrane transport systems, also allowing permeation of NO and hydrogen peroxide, a major ROS, in oxidative stress physiology and pathophysiology. (hindawi.com)
  • This notion has been challenged by the discovery of new membrane transport functions, especially those exerted by aquaporins (AQPs), a family of membrane channel proteins widespread in nature [ 10 , 11 ]. (hindawi.com)
  • Aquaporins (AQPs) facilitate transport of water and small solutes across cell membranes and play an important role in different physiological processes in plants. (biomedcentral.com)
  • The AQPs identified in the present study will serve as a resource for further characterization and possible exploitation of AQPs to understand their physiological role in A. hypogea . (biomedcentral.com)
  • Aquaporins (AQPs) are small (21-34 kD) integral membrane proteins, which form channels facilitating movement of water and other small solutes across the cell membrane. (biomedcentral.com)
  • Aquaporins (AQPs) are transmembrane water channels and some of them are permeable in addition to water to other small solutes including hydrogen peroxide. (bvsalud.org)
  • Aquaporins (AQPs) are water channel proteins that play a significant role in drought stress. (bvsalud.org)
  • Aquaporins (AQPs) are a family of transmembrane proteins present in all species that can be roughly divided into three subfamilies according to structure and function: 1) classical AQP, 2) aquaglyceroporin, and 3) superaquaporin. (bvsalud.org)
  • Various recent studies suggest that membrane channel proteins, named aquaporin (AQPs), by affecting stomatal conductance behavior could be involved in plant responses to stress conditions. (ac.ir)
  • مطالعات متعدد اخیر نشان می-دهد که پروتئین-های کانال غشایی به نام Aquaporin (AQPs) با تأثیر بر رفتار هدایت روزنه می- توانند در پاسخ گیاهان به شرایط تنش نقش داشته باشند. (ac.ir)
Plasma-membrane aquaporin3
  • 7(1): p. 87-95 Biela, A., K. Grote, B. Otto, S. Hoth, R. Hedrich, and R. Kaldenhoff, The Nicotiana tabacum plasma membrane aquaporin NtAQP1 is mercury-insensitive and permeable for glycerol. (wikipedia.org)
  • Otto, B. and R. Kaldenhoff, Cell-specific expression of the mercury-insensitive plasma-membrane aquaporin NtAQP1 from Nicotiana tabacum. (wikipedia.org)
  • Overexpression of a plasma membrane aquaporin in transgenic tobacco improves plant vigor under favorable growth conditions but not under drought or salt stress. (ac.ir)
Proteins3
  • Pioneering was Kaldenhoff's discovery that under investigation some of the aquaporin proteins facilitate the diffusion of CO₂ in plant tissues and cells and in chloroplasts respectively. (wikipedia.org)
  • Aquaporins and aquaglyceroporins belong to the ancient superfamily of Major Intrinsic Proteins (MIPs) and facilitate passive transport of water and small solutes across membranes of various organisms [ 1 , 2 ]. (biomedcentral.com)
  • Once bound to DNA, the proteins, in carrying out their functions, will crawl along the DNA strand in one of two directions, towards DNA's 3' or 5' end. (uiuc.edu)
Pore2
  • We developed a microfuidic system that allows the real time observation of the interactions between sweat and ACH in conditions mimicking physiological sweat fow and pore dimensions. (espci.fr)
  • By measuring the translocation of DNA through alpha-hemolysin , a membrane protein with a narrow pore, researches discovered that directed single stranded DNA moves much faster when entering the pore 3' end first, rather than 5' end first. (uiuc.edu)
Arabidopsis1
  • Heckwolf, M., D. Pater, D.T. Hanson, and R. Kaldenhoff, The Arabidopsis thaliana aquaporin AtPIP1;2 is a physiologically relevant CO transport facilitator. (wikipedia.org)
Processes1
  • Reactive oxygen species (ROS) are produced as a result of aerobic metabolism and as by-products through numerous physiological and biochemical processes. (hindawi.com)
Cellular2
  • At physiological levels, ROS can improve cellular activities as they are involved in the control of the chemical balance and synaptic plasticity [ 4 ], whereas an excess amount of ROS can damage the endothelium, leading to alteration of the intracellular reduction-oxidation homeostasis [ 5 ]. (hindawi.com)
  • The combination of 3-dimensional hydrogel cell cultures with microchip technology further allows (i) spatial and temporal control of cell growth, (ii) application of defined mechanical (e.g. shear, strain, stretch) and chemical (e.g. gradients) stimuli, as well as (iii) monitoring of dynamic cellular responses using integrated sensing strategies. (heraldopenaccess.us)
Important role1
  • Aquaporin 3 (AQP3) plays an important role in the expression of various skin-related diseases such as vitiligo and psoriasis. (e-ajbc.org)
Expression2
  • The response of a plant to drought stress is positively related to physiological traits and gene expression. (ac.ir)
  • However, there was not any clear relationship between physiological traits and expression of sunTIP7 gene in all six sunflower inbred lines. (ac.ir)
Water1
Transport1
  • Starting from single cell analysis using miniaturized flow cytometers [3] a variety of microfluidic devices have been developed for cell studies to investigate cell transport and cultivation in the absence and presence of concentration and temperature gradients or shear force conditions. (heraldopenaccess.us)
Analysis1
  • Semi-quantitative RT-PCR analysis showed that CaPIP2;3 and CaNIP3;1 are positive regulator, while CaSIP1;1 and CaPIP2;1 have a negative role in drought tolerance. (bvsalud.org)
Plant3
  • He is known for his work on the aquaporin protein class, where he detected facilitated diffusion of CO2 in plant tissue and cells and in chloroplasts respectively. (wikipedia.org)
  • Kaldenhoff was one of the first scientists to describe plant aquaporins. (wikipedia.org)
  • In the present review, molecular and physiological mechanisms explaining the observed beneficial effects plant derive from the Si supplementations, more particularly in horticultural species have been discussed. (researchsquare.com)
Vitro1
  • The application of hydrogels as a matrix for 3-dimensional cell cultures has become an indispensable tool in tissue engineering, biotechnology and biomedical research due to the improved functionality and viability of the in vitro biological system. (heraldopenaccess.us)
Recent1
  • This review focuses primarily on recent advances in biologically inspired microfluidic systems that are based on 3-dimensional hydrogel cell cultures and discusses advantages and current challenges, various applications of microfluidic hydrogel cell cultures and future perspectives. (heraldopenaccess.us)
Evidence1
  • For the first time, Kaldenhoff could provide evidence that an aquaporin molecule could conduct CO₂. (wikipedia.org)
Provide1
  • The narrow aromatic/arginine (ar/R) selectivity filter in MIPs has been shown to provide an important constriction for solute permeability. (biomedcentral.com)
Growth1
  • Drought conditions reduced crop growth and physiological traits. (ac.ir)
Cells1
  • by 3 months, all the fiber cells appeared swollen to a marked degree. (silverchair.com)
Aquaglyceroporins3
Membrane12
  • 7(1): p. 87-95 Biela, A., K. Grote, B. Otto, S. Hoth, R. Hedrich, and R. Kaldenhoff, The Nicotiana tabacum plasma membrane aquaporin NtAQP1 is mercury-insensitive and permeable for glycerol. (wikipedia.org)
  • Otto, B. and R. Kaldenhoff, Cell-specific expression of the mercury-insensitive plasma-membrane aquaporin NtAQP1 from Nicotiana tabacum. (wikipedia.org)
  • Aquaporins, members of membrane proteins discovered and characterized within the past 20 years, are the mechanism through which water is transported through living membranes. (medscape.com)
  • Aquaporins (AQPs), a family of membrane channel proteins involved in many body functions, are emerging among the targets of bioactive phytochemicals in imparting their beneficial actions. (frontiersin.org)
  • This review provides an update on the involvement of Aquaporins (AQPs), a family of membrane channel proteins with important role in many body functions, in the beneficial effects imparted by food polyphenols and herbal phytocompounds, both in health and disease. (frontiersin.org)
  • Furthermore, hypermotile capacitated sperm cells were examined, to determine the AQP7 expression and membrane glycerol permeability. (bvsalud.org)
  • Our findings indicate that AQP7 plays a key role in glycerol permeability, as the inhibition of AQP7 resulted in a 55% decrease in glycerol diffusion across the sperm membrane. (bvsalud.org)
  • Aquaporins (AQPs) are a family of membrane proteins involved in the transport of water and ions across cell membranes. (bvsalud.org)
  • Using ex vivo, in vitro and mutagenesis approaches, we determined that Avpr2aa plays a major role in the PKA-mediated phosphorylation of the aquaporin subdomains driving membrane insertion of Aqp1ab2 in the theca and granulosa cells, and of Aqp1ab1 and Aqp1ab2 in the distal and proximal regions of the oocyte microvilli, respectively. (bvsalud.org)
  • Aquaporins and membrane diffusion of CO2 in living organisms. (tu-darmstadt.de)
  • Expression and characterization of plasma membrane aquaporins in stomatal complexes of Zea mays. (tu-darmstadt.de)
  • The aquaporin TcAQP1 of the desert truffle Terfezia claveryi is a membrane pore for water and CO(2) transport. (tu-darmstadt.de)
AtPIP14
  • Heckwolf, M., D. Pater, D.T. Hanson, and R. Kaldenhoff, The Arabidopsis thaliana aquaporin AtPIP1;2 is a physiologically relevant CO transport facilitator. (wikipedia.org)
  • T-DNA insertion in aquaporin gene AtPIP1;2 generates transcription profiles reminiscent of a low CO2 response. (tu-darmstadt.de)
  • Transcriptome analysis of the aquaporin AtPIP1;2 deficient line in Arabidopsis thaliana. (tu-darmstadt.de)
  • The Arabidopsis thaliana aquaporin AtPIP1;2 is a physiologically relevant CO(2) transport facilitator. (tu-darmstadt.de)
Nicotiana1
  • Transgenic crop plant useful for generating tissue culture comprises root cell and leaf cell transformed with DNA construct having polynucleotide encoding Nicotiana tabacum aquaporin-1. (tu-darmstadt.de)
Permeable1
Protein7
  • He is known for his work on the aquaporin protein class, where he detected facilitated diffusion of CO2 in plant tissue and cells and in chloroplasts respectively. (wikipedia.org)
  • [ 4 ] Within 3 years (1988), an abundant 28-kDa protein was noted during purification of another 32-kDa core polypeptide of erythrocytes. (medscape.com)
  • HN - 2006(1981) BX - Cofilins MH - Actin-Related Protein 2 UI - D051377 MN - D5.750.78.730.246.500 MN - D12.776.220.525.246.500 MS - A PROFILIN binding domain protein that is part of the Arp2-3 complex. (nih.gov)
  • Arp2-3 complex binds WASP PROTEIN and existing ACTIN FILAMENTS, and it nucleates the formation of new branch point filaments. (nih.gov)
  • HN - 2006 BX - Arp2-3 Complex MH - Actin-Related Protein 3 UI - D051378 MN - D5.750.78.730.246.750 MN - D12.776.220.525.246.750 MS - A component of the Arp2-3 complex that is related in sequence and structure to ACTIN and that binds ATP. (nih.gov)
  • Co-Translational Insertion of Aquaporins into Liposome for Functional Analysis via an E. coli Based Cell-Free Protein Synthesis System. (tu-darmstadt.de)
  • The autophagy protein LC3, a mammalian homologue of Atg8, was originally identified as microtubule-associated protein 1 light chain 3. (thermofisher.com)
Roles2
  • 11. Roles of aquaporin-3 in the epidermis. (nih.gov)
  • The roles of Na+/H+exchanger regulatory factor 1 and Aquaporin-1 in the pathomechanism of experimental acute pancreatitis. (u-szeged.hu)
Homeostasis3
  • 1. Skin aquaporins: function in hydration, wound healing, and skin epidermis homeostasis. (nih.gov)
  • 9. Molecular and cellular regulation of water homeostasis in anuran amphibians by aquaporins. (nih.gov)
  • AQPs have been shown to be implicated in various physiological and pathological processes in the brain, including water homeostasis, cell migration, and inflammation, among others. (bvsalud.org)
Pores1
Hydration1
  • The dual aquaporin (Aqp1ab1/Aqp1ab2)-mediated hydration of marine teleost eggs, which occurs during oocyte meiosis resumption (maturation), is considered a key adaptation underpinning their evolutionary success in the oceans. (bvsalud.org)
Biosynthesis2
  • 6. Hydrating skin by stimulating biosynthesis of aquaporins. (nih.gov)
  • use DICARBOXYLIC ACIDS 1970-1979 MH - 3-Phosphoshikimate 1-Carboxyvinyltransferase UI - D051229 MN - D8.811.913.225.735 MS - An enzyme of the shikimate pathway of AROMATIC AMINO ACID biosynthesis, it generates 5-enolpyruvylshikimate 3-phosphate and ORTHOPHOSPHATE from PHOSPHOENOLPYRUVATE and SHIKIMATE-3-PHOSPHATE. (nih.gov)
Kaldenhoff2
  • Kaldenhoff was one of the first scientists to describe plant aquaporins. (wikipedia.org)
  • For the first time, Kaldenhoff could provide evidence that an aquaporin molecule could conduct CO₂. (wikipedia.org)
Vivo1
Targets2
  • The presence of aquaporins explains disease etiology related to water physiology and presents new pharmacogenomic targets. (medscape.com)
  • In this article, we review the literature on aquaporins found in Apicomplexan, Kinetoplastida and Microsporidia parasites as potential drug targets. (medscape.com)
Conductance1
  • The grapevine root-specific aquaporin VvPIP2;4N controls root hydraulic conductance and leaf gas exchange under well watered conditions but not under water stress. (tu-darmstadt.de)
Clinical1
  • This information now provides the challenge of developing new technologies to manipulate aquaporins for clinical or agricultural benefits. (nih.gov)
Human1
  • 4. All-trans retinoic acid attenuates ultraviolet radiation-induced down-regulation of aquaporin-3 and water permeability in human keratinocytes. (nih.gov)
Plants1
  • The enhanced drought tolerance of rice plants under ammonium is related to aquaporin (AQP). (tu-darmstadt.de)
Functions2
  • 7. Aquaporin-3 functions as a glycerol transporter in mammalian skin. (nih.gov)
  • 14. Glycerol and the skin: holistic approach to its origin and functions. (nih.gov)
Water channel1
  • This became the chance discovery of the aquaporin (AQP) water channel. (medscape.com)
Found1
Cell1
  • 13. Aquaporin-3 facilitates epidermal cell migration and proliferation during wound healing. (nih.gov)
Stopped-flow1
  • Subsequently, the glycerol permeability of spermatozoa obtained from normozoospermic individuals (n = 30) was measured, using stopped-flow light scattering, after incubation with specific aquaporin inhibitors targeting AQP3 (DFP00173), AQP7 (Z433927330), or general aquaglyceroporin (phloretin). (bvsalud.org)
Group1
  • 9/3/2005) TOTAL DESCRIPTORS = 935 MH - 1-Acylglycerol-3-Phosphate O-Acyltransferase UI - D051103 MN - D8.811.913.50.173 MS - An enzyme that catalyzes the acyl group transfer of ACYL COA to 1-acyl-sn-glycerol 3-phosphate to generate 1,2-diacyl-sn-glycerol 3-phosphate. (nih.gov)
Type1
  • The 2,3,7,8-tetrachlorodibenzo-p-dioxin type SLC33A1 uses lipidome nucleus AT1( Kanamori et al. (evakoch.com)