• Central to physiological functioning are biophysical and biochemical processes, homeostatic control mechanisms, and communication between cells. (wikipedia.org)
  • Here we review recent insights into the biophysical, biochemical, and epigenetic processes that underlie regenerative healing in amphibians, focusing particularly on tail and limb regeneration in Xenopus . (frontiersin.org)
  • The book focuses on recent biochemical and biophysical advances and the molecular biological techniques that have made them possible. (princeton.edu)
  • It then moves through biochemical and molecular biological patterns in aquatic photoautotrophs, physiological and ecological principles, and global biogeochemical cycles. (princeton.edu)
  • In this project we will use a combined approach using computer-based methods including virtual screening of molecular databases and biochemical/biophysical techniques as well as X-ray crystallography to develop cofactor-specific inhibitors. (uni-wuerzburg.de)
  • We use a wide range of biophysical, biochemical, cell biological, and genetic approaches to uncover the general principles underlying regulation of the actin cytoskeleton, and to reveal how defects in actin dynamics affect the physiological functions of cells. (helsinki.fi)
  • From this, the central role of the heart is explored in terms of biochemical, biophysical and energetic interactions. (heartmath.org)
  • This can involve reduction of a physiological trait to biochemical or biophysical processes and ultimately a gene or genes. (plantphenomics.org.au)
  • Although less familiar than genetic or biochemical aspects, physical forces have emerged as key regulators of cellular processes. (wur.nl)
  • This goal is being pursued with a combination of theoretical and experimental approaches at several levels of investigation ranging from the biophysical level to the systems level. (stanford.edu)
  • Peripheral sensory research combines cell-physiological and biophysical approaches with molecular strategies for the investigation of cellular signaling complexes in the sensory cells of ear, eye, and nose. (uni-goettingen.de)
  • Systems physiology and computational approaches are used to elucidate processing principles and circuit plasticity in the auditory system of insects and in the primate visual cortex, where also the modulation by attention is studied. (uni-goettingen.de)
  • To achieve our goals, we develop biophysical approaches and make use of high-resolution imaging, advanced molecular biology, as well as quantitative data analysis. (wur.nl)
  • Therefore, authors are invited to submit original research and review articles which address the progress and current standing of cellular signalling processes. (mdpi.com)
  • Cell migration is a universal feature of all metazoan life and crucially involved in most developmental, homeostatic and pathological processes. (europa.eu)
  • Molecular interactions in cell membranes, particularly lipid-protein interactions in their hydrophobic core, are difficult to analyse and remain poorly characterised despite high relevance in physiological and pathological processes. (mappingignorance.org)
  • He is a recipient of the EMBO Young Investigator award, the 2017 City of Barcelona award to the life sciences, and the 2019 Young Investigator Award of the European Biophysical Societies Association (EBSA). (ibecbarcelona.eu)
  • Human physiology is examined through homeostasis, and the biophysical properties of cells, tissues, and organs. (yale.edu)
  • The mechanisms of developmental bioelectricity - the ability of all cells to form electrical networks that process information - suggests a plausible set of gradual evolutionary steps that naturally lead from physiological homeostasis in single cells to memory, prediction, and ultimately complex cognitive agents, via scale-up of the drive of infotaxis. (philpapers.org)
  • The AAA ATPase p97 is an essential protein involved in numerous cellular processes and plays a key role in multiple aspects of protein homeostasis. (uni-wuerzburg.de)
  • The organization and dynamics of actin filament must be precisely controlled during these processes, and consequently defects in regulation of the actin cytoskeleton lead to various diseases including cancer progression, as well as neurological and immunological disorders. (helsinki.fi)
  • Topics such as lysosomal dynamics, the biophysical challenges of bending membranes, and the evolution of endocytic systems are also covered. (cshlpress.com)
  • Through fine modulation of target properties, studying cytoskeletal dynamics, and measuring cellular forces, we aim to establish a better understanding of the plasticity of this important immunological process. (wur.nl)
  • The "slow" processes of individual allocation and growth, population dynamics and disturbance are implemented once each simulation year (Figure 1). (lu.se)
  • pH has a strong influence upon the availability of mineral nutrients needed for plant growth and developmental processes. (globalsciencebooks.info)
  • It is thus an indispensable reference for cell biologists, but also for neuroscientists, immunologists, developmental biologists, microbiologists, and others concerned with the physiological and therapeutic implications of this key cellular process. (cshlpress.com)
  • These communication networks are examined from an information processing perspective and reveal a fundamental order in heart-brain interactions and a harmonious synchronization of physiological systems associated with positive emotions. (heartmath.org)
  • Structural rearrangements in membranes and embedded proteins, and the way molecular interactions contribute to their function are unresolved questions in biophysical chemistry. (mappingignorance.org)
  • Incorporation of hydroxyapatite (HA) in a collagen scaffold dramatically improves bone morphogenic protein (BMP) sequestration via biophysical interactions with BMP, thereby providing more controlled BMP release compared with pristine collagen. (lu.se)
  • Protein-protein interactions are crucial in numerous cellular functions and biological processes that take place inside our body. (lu.se)
  • Laboratory experiences integrated with lecture enable students to examine anatomical and physiological phenomena of the human body. (wvstateu.edu)
  • G-protein-coupled receptors (GPCRs) modulate many physiological processes by transducing a variety of extracellular cues into intracellular responses. (nih.gov)
  • She also studies how social behaviors are regulated according to sensory stimuli, context, internal state, and physiological status, and how these factors modulate neural circuit function via a combinatorial code of classic neuromodulators and immune-derived cytokines. (mit.edu)
  • The research goals are to elucidate cellular mechanisms of normal and impaired peripheral and central sensory processing, to explore sensorimotor transformation, the modulation of sensory and motor function and to study goal-directed behavior. (uni-goettingen.de)
  • This proposal suggests a combined cell biological and biophysical approach to elucidate the molecular and mechanical principles underlying such plasticity. (europa.eu)
  • The association pathway from monomer to oligomer is critical in a range of biological processes and thus it is of a vital importance to elucidate both atomic-resolution structures of intermediates along the pathway as well as the structure of the final state. (lu.se)
  • Biophysical models of electrical and chemical signal processing within neurons are used as an adjunct to physiological experiments. (stanford.edu)
  • In conclusion, with the multipolar cell morphology and three physiological firing patterns, these neurons may be playing important roles in the processing of sound information mediating the reflexive orienting responses of the eye, head and body. (tubitak.gov.tr)
  • 2016. Endothelial Cells Use a Formin-Dependent Phagocytosis-Like Process to Internalize the Bacterium Listeria monocytogenes . (washington.edu)
  • A combined cell-physiological and genetic approach to the calyx of Held synapse is used to explore the mechanisms underlying temporal acuity, reliability, and plasticity of information processing in the auditory brainstem. (uni-goettingen.de)
  • Whereas the mechanisms activating mechanotransduction are well studied, the reversibility of this process, whereby cells disassemble and reverse force-activated signalling pathways upon cessation of mechanical stimulation is far less understood. (ibecbarcelona.eu)
  • Therefore, the understanding of the diverse signalling molecules, signal recognition mechanisms and signal transduction pathways is fundamental for the insight into physiological and pathophysiological processes. (mdpi.com)
  • Growth regulators are also involved, although the mechanisms of these complex and interactive processes require elucidation. (globalsciencebooks.info)
  • The lab employs cutting-edge computational and biophysical methods to monitor single receptor molecules in real-time to decipher their functional mechanisms. (rgcb.res.in)
  • Further evaluation of the molecular mechanisms responsible for this increased osteoinductivity at an early stage in the regeneration process indicated that the CHA+BMP-2/7 enhanced progenitor cell homing at the implantation site, upregulated the key transcriptomic determinants of bone formation, and increased the production of bone extracellular matrix components. (lu.se)
  • A growing body of research now indicates that early physiological injury responses are also required to initiate a regenerative program, and that these differ in regenerative and non-regenerative contexts. (frontiersin.org)
  • Deformable microspheres are great tools for understanding the role of physical forces in biology because they expand the range of physiological contexts where such measurements can be made. (wur.nl)
  • Multiple technological challenges lie ahead to realize this full potential: more detailed and comprehensive mechanical measurements can be achieved and optimized for use in specific physiological contexts. (wur.nl)
  • This second edition, thoroughly revised to bring it up to date, describes how one of the most fundamental metabolic processes evolved and transformed the surface chemistry of the Earth. (princeton.edu)
  • This fundamental process of cellular ingestion is required for diverse activities such as nutrient uptake, cell adhesion and migration, signal transduction, cytokinesis, neurotransmission, and antigen presentation. (cshlpress.com)
  • Due to its significant role in regulating a variety of physiological responses, p97 has emerged as a potential therapeutic target. (uni-wuerzburg.de)
  • It provides insights into the genetic basis of physiological processes and the ways in which genes interact with the environment to influence an organism's phenotype. (wikipedia.org)
  • Neurotransmitter receptors act as a bridge between cells in the central and peripheral nervous systems and are required for various physiological activities. (rgcb.res.in)
  • Our research group seeks to understand the biophysical and molecular processes of neurotransmitter receptors during normal and pathological conditions. (rgcb.res.in)
  • We recently performed a genome-wide CRISPR screen to identify regulators of this process, and are now trying to establish how known and novel regulators, including receptors, precisely function in efferocytosis. (wur.nl)
  • However, dysregulations of these signalling pathways are also causes for pathophysiological processes and diseases. (mdpi.com)
  • This process is increasingly recognized as a target for therapeutic intervention in the context of atherosclerosis, neurodegenerative disease, and cancer. (wur.nl)
  • In endomyocardial fibrosis (EMF), the underlying process produces patchy fibrosis of the endocardial surface of the heart, leading to reduced compliance and, ultimately, restrictive physiology as the endomyocardial surface becomes more generally involved. (medscape.com)
  • In ten chapters that are self-contained but that build upon information presented earlier, the book starts with a reductionist, biophysical description of the photosynthetic reactions. (princeton.edu)
  • However, IL-6 signaling blockade should consider the inhibition of inflammatory processes and the regenerative functions of IL-6. (bvsalud.org)
  • Large-scale protein conformational motions on nanosecond-microsecond time scales are important for many biological processes, but remain largely unexplored because of methodological limitations. (lu.se)
  • Many cellular processes help a protein to gain the defined structure needed to function, or are involved in the clearance of non-functional misfolded proteins. (arbre-mobieu.eu)
  • Proteins of any size can be studied at physiological hydration levels with this method. (lu.se)
  • Screens might include abiotic or biotic stress challenges and must be reproducible and of physiological relevance. (plantphenomics.org.au)
  • There Marx referred to "the squandering of the vitality of the soil" by large-scale capitalist enterprise, generating "an irreparable rift in the interdependent process of social metabolism, a metabolism prescribed by the natural laws of life itself. (monthlyreview.org)
  • Diffusion tensor image processing: we seek for candidates with experience in tensor-based image processing, diffusion tensor image analysis, connectivity analysis, fibre tracking, statistical modelling of fibre tracks, tensor processing. (vph-institute.org)
  • We aim at linking biophysical models of brain tissue degeneration with MRI intensity modelling through machine learning. (vph-institute.org)
  • Modelling of circadian and lifestyle physiological changes: we are seeking an outstanding candidate with background in signal processing and modelling to develop circadian and lifestyle models of physiological signal variability based on pervasive sensing and monitoring. (vph-institute.org)
  • The ideal candidate will have substantive expertise in control theory, signal processing, system identification and physiological modelling. (vph-institute.org)
  • By taking the "guesswork" out of the writing process, students can focus on the development of their research proposal without the added anxiety associated with an unfamiliar process. (yale.edu)
  • At the heart of our research is a biophysical technique I developed during my postdoc. (wur.nl)
  • Evolutionary biology is the study of the processes that have led to the diversity of life on Earth. (wikipedia.org)
  • The scope of the special issue is to summarize and enlarge the knowledge in signalling processes and networks in diverse cells and tissues. (mdpi.com)
  • Small-footprint airborne laser scanning (ALS) data proved valuable for characterising the three-dimensional structure of forest canopies and the retrieval of biophysical parameters such as plant and leaf area index (PAI and LAI), fractional cover or canopy layering. (uzh.ch)
  • Consequently, this will lead to erroneous retrieval of biophysical parameters. (uzh.ch)
  • It is necessary to know the thermophysical parameters of granular mass to ensure the quality of the technological processes. (international-agrophysics.org)
  • The time process of temperature which is related to the thermophysical parameters of samples was analysed. (international-agrophysics.org)
  • They do this by engulfing and subsequently degrading them in a process called efferocytosis. (wur.nl)
  • Disregulation of these processes can lead to non-physiological protein conformations and subsequently the onset of disease. (arbre-mobieu.eu)
  • They maintain central physiological processes such as vision, scent, or blood pressure regulation. (biophysics.org)
  • Fast" process, such as photosynthesis, respiration and stomatal regulation are implemented on a time step of one day (or one month, interpolating between output values for adjacent months to obtain a value for each day). (lu.se)
  • Adventitious root formation is the primary regeneration process required for the successful propagation of cuttings. (globalsciencebooks.info)
  • Interleukin (IL-) 6 is a critical factor in inflammatory processes of rheumatoid arthritis (RA). (bvsalud.org)
  • Hypotheses include infectious, inflammatory, and nutritional processes. (medscape.com)
  • He is also the President of the Neural Information Processing Systems Foundation, a non-profit organization that oversees the annual NIPS Conference. (stanford.edu)
  • PHAR 550a Physiological Systems. (yale.edu)
  • Blood clot formation is crucial to maintain normal physiological conditions but at the same time involved in many diseases. (maastrichtuniversity.nl)
  • The mechanical properties of the blood clot are important for its functioning but complicated due to the many processes involved. (maastrichtuniversity.nl)
  • Replacing hydrogen by fluorine with its 20% larger atomic radius and higher electronegativity is a chemical modification with possible impact on the lipid's biophysical properties. (mappingignorance.org)
  • Protein misfolding is fundamentally a biophysical problem, amenable to multiscale analysis using complementary techniques, that could also provide a basis for novel biophysical applications. (arbre-mobieu.eu)
  • Indeed, the water deficit imposes itself as extrinsic factor that negatively influences the germination of seeds due to the essential and vital role of water in the induction of recovery of metabolic activity during germination process. (scirp.org)
  • Our aim is to understand how chronic biophysical conditions may influence image appearance in dementia patients so as to develop image-based biomarkers underpinned by mechanistic understanding of tissue degeneration. (vph-institute.org)
  • We can try to understand what look like very complicated processes in the living animal with relatively simple physics," Collins says. (zmescience.com)
  • In both processes, rapid proliferation gives rise to new tissue, cell fate has to be specified within that tissue, and distinct positional identities have to be established to generate a properly patterned structure. (frontiersin.org)
  • One such input is mechanical force, which activates signalling and regulates cell behaviour in the process of mechanotransduction. (ibecbarcelona.eu)
  • This satellite meeting will be focused on how molecular-scale biophysical methods can be applied to the timely study of biomedically-pressing issues. (arbre-mobieu.eu)
  • Physiological state is the condition of normal function. (wikipedia.org)
  • The goal is to utilise the derived models to establish personalised and lifestyle-specific boundary conditions for image-based patient-specific biophysical models. (vph-institute.org)
  • Capitalist production, therefore, only develops the techniques and the degree of combination of the social process of production by simultaneously undermining the original sources of all wealth-the soil and the worker. (monthlyreview.org)
  • Biochemistry is the study of the chemical processes and substances that occur within living organisms. (wikipedia.org)
  • Because the hydra is such a simple animal, it offers researchers the possibility to study the process in detail. (zmescience.com)