• We demonstrate here that the kinases Gsk3β and cAMP-dependent protein kinase A (PKA) are novel determinants of IZ formation and cooperate with E(Spl) activity in a dose-dependent manner. (biologists.com)
  • The proposed mechanisms of such rapid receptor desensitization include receptor phosphorylation by either cAMP-dependent protein kinase or the specific beta-adrenergic receptor kinase (BARK), leading to functional uncoupling from adenylyl cyclase and sequestration of the receptors away from the cell surface. (jci.org)
  • cAMP exerts its effects by activating the cAMP-dependent protein kinase (AMPK), which transduces the signal through phosphorylation of different target proteins. (thermofisher.com)
  • We show that this dual phenotype results from elevated cAMP levels and hyperactivation of the cAMP-dependent protein kinase (PKA). (crick.ac.uk)
  • The type II receptor is a serine/threonine receptor kinase, which catalyzes the phosphorylation of the Type I receptor. (wikipedia.org)
  • These receptors are serine/threonine kinase receptors. (wikipedia.org)
  • The Type II receptor phosphorylates serine residues of the Type I receptor, which activates the protein. (wikipedia.org)
  • Background: Tropomyosin 1 alpha chain (Tm1) is an actin-binding protein that regulates the endothelial cell response to oxidative stress following its phosphorylation at Serine 283 (S283). (scirp.org)
  • The 3a protein was found to induce serine phosphorylation within the IFN alpha-receptor subunit 1 (IFNAR1) degradation motif and to increase IFNAR1 ubiquitination. (nih.gov)
  • A protein serine-threonine kinase that catalyzes the PHOSPHORYLATION of I KAPPA B PROTEINS. (uchicago.edu)
  • Phosphatase Inhibitor Cocktail protects phosphoproteins from serine/threonine phosphatases as well as protein tyrosine phosphatases (PTPs) during cell lysis. (celltechgen.com)
  • SMAD5 is activated through serine phosphorylationby BMP (bone morphogenetic proteins) type 1 receptor kinase. (biopaqc.com)
  • This stimulation of cAMP was not Ca 2+ -sensitive and was unaffected by a range of protein kinase inhibitors. (jneurosci.org)
  • 3 hr, and is reduced by inhibitors of PKA and of protein or RNA synthesis. (jneurosci.org)
  • Three-train L-LTP was also blocked by inhibitors of guanylyl cyclase or cGMP-dependent protein kinase (PKG). (jneurosci.org)
  • Conversely, either NO or cGMP analogs paired with one-train tetanization produced late-phase potentiation, and the cGMP-induced potentiation was blocked by inhibitors of protein or RNA synthesis and an inhibitor of PKG, but not by an inhibitor of PKA. (jneurosci.org)
  • The binding of PKC betaII to actin was not inhibited by kinase inhibitors of PKC (sphingosine and staurosporine), suggesting that prior activation and/or substrate phosphorylation are not required for the interaction of PKC betaII with actin. (duke.edu)
  • The response to GLP-1 was mimicked by forskolin and largely inhibited by the protein kinase A (PKA) inhibitors, H89 and myristoylated PKI(14-22) amide, indicating partial mediation via a cAMP/PKA pathway. (diabetesjournals.org)
  • The cocktail contains a mixture of four inhibitors of broad specificity, including sodium fluoride, sodium orthovanadate, sodium pyrophosphate and beta-glycerophosphate. (celltechgen.com)
  • Mitogen-activated protein kinases (MAPKs) comprise a large family of proteins activated by a wide range of proinflammatory cytokines and environmental stress. (molvis.org)
  • The p38 mitogen-activated protein kinases (p38 MAP kinases) are a family of four related Ser/Thr kinases responsive to pro-inflammatory cytokines and environmental stresses, including ionizing radiation, oxidative stress, and osmotic shock. (rndsystems.com)
  • PRKACB is a member of the Ser/Thr protein kinase family and is a catalytic subunit of AMPK. (thermofisher.com)
  • This enzyme also activates the transcription factor NF-KAPPA B and is composed of alpha and beta catalytic subunits, which are protein kinases and gamma, a regulatory subunit. (uchicago.edu)
  • and Its Interaction with Kaposi Sarcoma-associated Herpes Virus Flice-interacting Protein and IKK Subunit ß by EPR Spectroscopy. (uchicago.edu)
  • Platelet-derived growth factor receptors (PDGFRs) exhibit tyrosine-protein kinase activity and have been implicated in the control of cell proliferation, survival and migration. (loinc.org)
  • The binding of a TGFβ family ligand causes the rotation of the receptors so that their cytoplasmic kinase domains are arranged in a catalytically favorable orientation. (wikipedia.org)
  • Studies of Ig alpha or Ig beta have shown that the immunoreceptor tyrosine-based activation motif (ITAM) found in each cytoplasmic tail is capable of inducing most receptor signaling events. (nih.gov)
  • It is cytoplasmic in the absenceof its ligand and migrates into the nucleus upon phosphorylation and complex formation withSMAD4. (biopaqc.com)
  • Houle, F., Poirier, A., Dumaresq, J. and Huot, J. (2007) DAP Kinase Mediates the Phosphorylation of Tropomyosin-1 Downstream of the ERK Pathway, Which Regulates the Formation of Stress Fibers in Response to Oxidative Stress. (scirp.org)
  • Here, we report that GIT1 overexpression regulates internalization of numerous, but not all, G protein-coupled receptors. (duke.edu)
  • Protein kinase C-alpha phosphorylation of specific serines in the connecting segment of the beta 4 integrin regulates the dynamics of type II hemidesmosomes. (umassmed.edu)
  • This protein initially was identified as an interacting partner for the G protein-coupled receptor kinases, and its overexpression was found to affect signaling and internalization of the prototypical beta(2)-adrenergic receptor. (duke.edu)
  • Monoclonal antibodies reveal receptor specificity among G-protein-coupled receptor kinases. (duke.edu)
  • Receptor and G betagamma isoform-specific interactions with G protein-coupled receptor kinases. (duke.edu)
  • The mitogenic action of VEGF , a potent hypoxia -induced angiogenic factor , was increased by 2-fold in retinal endothelial cells by the overexpression of PKC beta 1 or beta 2 isoforms and inhibited significantly by the overexpression of a dominant-negative PKC beta 2 isoform but not by the expression of PKC alpha, delta , and zeta isoforms . (bvsalud.org)
  • Tyrosine phosphorylation on spleen tyrosine kinase (Syk) is differentially regulated in human and murine platelets by protein kinase C isoforms. (jefferson.edu)
  • We have demonstrated a dramatic increase in the angiogenic response to oxygen -induced retinal ischemia in transgenic mice overexpressing PKC beta 2 isoform and a significant decrease in retinal neovascularization in PKC beta isoform null mice . (bvsalud.org)
  • Association of PKC beta 2 isoform with retinoblastoma protein was discovered in retinal endothelial cells , and PKC beta 2 isoform increased retinoblastoma phosphorylation under basal and VEGF -stimulated conditions. (bvsalud.org)
  • Differential phosphorylation and isoform expression of tau are believed to regulate the assembly and stabilisation of microtubuli. (europa.eu)
  • Adenosine monophosphate-activated protein kinase (AMPK) activation is suggested to relax smooth muscle by endothelial nitric oxide synthase (eNOS) phosphorylation. (korea.ac.kr)
  • To assess the mechanism and effect of a novel AMPK activator, beta-lapachone, upon cavernosal smooth muscle relaxation and the therapeutic potential for erectile dysfunction. (korea.ac.kr)
  • The expression of p-AMPK, p-eNOS, AMPK and eNOS induced by beta-lapachone in HUVECs study and the percent relaxation of cavernosal tissue in organ bath study. (korea.ac.kr)
  • Beta-lapachone clearly induced AMPK phosphorylation and, as a consequence, eNOS phosphorylation in HUVECs. (korea.ac.kr)
  • A novel AMPK activator, beta-lapachone has a strong relaxation effect on precontracted cavernosal smooth muscle strips in the rabbit. (korea.ac.kr)
  • And phosphorylation of AMPK and eNOS strongly related to the action of beta-lapachone. (korea.ac.kr)
  • Mathematical modeling of signal transduction networks has previously been used to map out thermodynamical using rate equations is increasingly attracting attention as a properties of protein-folding models (6,7). (lu.se)
  • The TGF beta ligand binds to a type II receptor dimer, which recruits a type I receptor dimer forming a hetero-tetrameric complex with the ligand. (wikipedia.org)
  • Scholars@Duke publication: Protein kinase C beta II specifically binds to and is activated by F-actin. (duke.edu)
  • Transcription factor that binds to the interleukin-6 (il-6)-responsive elements identified in the promoters of various acute-phase protein genes. (lu.se)
  • Furthermore, the GIT1 effect is not limited to G protein-coupled receptors because overexpression of this protein also affects internalization of the epidermal growth factor receptor. (duke.edu)
  • Overexpression of tau kinase cdk5 activator p25 resulted in gliosis. (europa.eu)
  • The human trabecular meshwork cells were treated with t BHP for 1 or 2 h with or without pretreatment of SB203580, an inhibitor of MAP kinase homologs. (molvis.org)
  • Olsson PO, Gustafsson R, In 't Zandt R, Friman T, Maccarana M, Tykesson E, Oldberg Å, Rubin K, Kalamajski S. The Tyrosine Kinase Inhibitor Imatinib Augments Extracellular Fluid Exchange and Reduces Average Collagen Fibril Diameter in Experimental Carcinoma. (lu.se)
  • In colon-derived cell lines where Yap is overabundant, its depletion strongly reduces beta-catenin and Notch signaling and inhibits proliferation and survival. (harvard.edu)
  • Two such proteins that mediate the TGFβ pathway include SARA (the SMAD anchor for receptor activation) and HGS (Hepatocyte growth factor-regulated tyrosine kinase substrate). (wikipedia.org)
  • 2-fold increase in phosphorylation at over 200 phosphosites, more than half of which conform to a PKA substrate consensus sequence. (crick.ac.uk)
  • For p38 beta, also known as p38-2, stress-activated protein kinase 2B (SAPK2B), and MAPK11, this dual phosphorylation occurs at Thr180/Tyr182. (rndsystems.com)
  • The study confirmed that EPA reduced concentrations of the pro-inflammatory interleukin 1-beta in rats, and also showed phosphorylation of the stress-activated protein kinase, c-jun N-terminal kinase. (bioworld.com)
  • Multiple endocytic pathways of G protein-coupled receptors delineated by GIT1 sensitivity. (duke.edu)
  • Receptors transduce these signals to alter intracellular metabolism and cellular responsiveness through heterotrimeric G protein/second messenger pathways or through small GTP-binding protein/protein kinase cascades. (duke.edu)
  • Since ER stress can cause differential modulation of the unfolded protein response (UPR), which includes the inositol-requiring enzyme 1 (IRE-1), activating transcription factor 6 (ATF6) and PKR-like ER kinase (PERK) pathways, these were individually tested in 3a-expressing cells. (nih.gov)
  • The TGF beta superfamily of ligands includes: Bone morphogenetic proteins (BMPs), Growth and differentiation factors (GDFs), Anti-müllerian hormone (AMH), Activin, Nodal and TGFβs. (wikipedia.org)
  • Signaling begins with the binding of a TGF beta superfamily ligand to a TGF beta type II receptor. (wikipedia.org)
  • It is areceptor-regulated SMAD (R-SMAD), and acts as an intracellular signal transducer for thetransforming growth factor beta superfamily. (biopaqc.com)
  • Belongs to the protein kinase superfamily. (lu.se)
  • Activation of beta 2 -adrenergic receptors on airway smooth muscle leads to the activation of adenylyl cyclase and to an increase in the intracellular concentration of cyclic-3',5'-adenosine monophosphate (cyclic AMP). (theodora.com)
  • PDGF receptors, PDGFR-alpha and PDGFR-beta, have 5 extracellular immunoglobulin-like domains and an intracellular tyrosine kinase domain. (loinc.org)
  • Recent studies have suggested that dopamine D2 receptor antagonists, which are used in the clinical treatment of schizophrenia, modulate protein kinase B (Akt)/glycogen synthase kinase (GSK)-3 signaling. (biomedcentral.com)
  • GSK-3 is a protein kinase originally identified and named for its ability to phosphorylate and inactivate the metabolic enzyme glycogen synthase [ 11 ]. (biomedcentral.com)
  • Here we will focus on HMG AT-hook 2 protein (HMGA2), a member of the HMGA family that mediates transforming growth factor beta 1 (TGFB1, commonly known as TGFβ1) signaling 16 . (nature.com)
  • Phosphorylation induces a conformational change in the MH2 domain of the R-SMAD and its subsequent dissociation from the receptor complex and SARA. (wikipedia.org)
  • Here we show that high-mobility group AT-hook 2 protein (HMGA2) induces DNA nicks at the transcription start site, which are required by the histone chaperone FACT complex to incorporate nucleosomes containing the histone variant H2A.X. Further, phosphorylation of H2A.X at S139 (γ-H2AX) is required for repair-mediated DNA demethylation and transcription activation. (nature.com)
  • Activation of protein kinase C (PKC) enhances the angiogenic process and is involved in the signaling of vascular endothelial growth factor ( VEGF ). (bvsalud.org)
  • Treatment of the pertussis toxin-treated cells with cholera toxin before CB1 receptor activation amplified the stimulatory pathway, suggesting that this response was mediated through a G s -type G-protein. (jneurosci.org)
  • Cannabinoids exert many of their effects through activation of G i -protein-coupled receptors. (jneurosci.org)
  • Each family member, p38 alpha, p38 beta, p38δ, and p38 gamma, is activated by dual Thr and Tyr phosphorylation within a Thr-Gly-Tyr motif residing in the kinase activation loop. (rndsystems.com)
  • Diminished phosphorylation, enhanced abundance, and nuclear localization of the transcriptional coactivator Yes-associated protein 1 (Yap1) is evident in Mst1/Mst2-deficient intestinal epithelium, as is strong activation of beta-catenin and Notch signaling. (harvard.edu)
  • Cells expressing the 3a proteins showed ER stress based on activation of genes for the ER chaperones GRP78 and GRP94. (nih.gov)
  • Only the PERK pathway was found to be activated in 3a-expressing cells based on (1) increased phosphorylation of eukaryotic initiation factor 2 alpha (eIF2alpha) and inhibitory effects of a dominant-negative form of eIF2alpha on GRP78 promoter activity, (2) increased translation of activating transcription factor 4 (ATF4) mRNA, and (3) ATF4-dependent activation of the C/EBP homologous protein (CHOP) gene promoter. (nih.gov)
  • Conclusion: Phosphorylation of Tm1 at Ser283 contributes to its anti-tumor properties, and this effect results mainly from an increase in cell adhesion associated with a decrease in their migratory and invasive potentials. (scirp.org)
  • Expression levels of PER2, a clock protein, were elevated in Sik3 -knockdown cells but down-regulated in Sik3 -overexpressing cells, which could be attributed to a phosphorylation-dependent decrease in PER2 protein stability. (elifesciences.org)
  • Beta-blockers: May decrease effectiveness of PROAIR RESPICLICK and produce severe bronchospasm. (nih.gov)
  • Active DNA demethylation also requires GADD45A (growth arrest and DNA damage protein 45 alpha) and TET1 (ten-eleven translocation methylcytosine dioxygenase 1), which sequentially oxidize 5-methylcytosine (5mC) to 5-carboxylcytosine (5caC) 18 , 19 and are cleared through DNA repair mechanisms. (nature.com)
  • Thus, chronic administration of opioids modifies neuronal MOR function through a variety of mechanisms including receptor phosphorylation, signaling, multimerization, and trafficking, which may underlie tolerance to morphine. (hindawi.com)
  • And d) Another very basic problem is that cancer cells tend to be remarkably clever and naturally seek to take advantage of numerous cellular survival mechanisms to stay alive under stress, for example by upregulating heat shock proteins or DNA repair mechanisms. (anti-agingfirewalls.com)
  • The transforming growth factor beta (TGFB) signaling pathway is involved in many cellular processes in both the adult organism and the developing embryo including cell growth, cell differentiation, cell migration, apoptosis, cellular homeostasis and other cellular functions. (wikipedia.org)
  • GIT1 only affects the function of G protein-coupled receptors that are internalized through the clathrin-coated pit pathway in a beta-arrestin- and dynamin-sensitive manner. (duke.edu)
  • Thus, GIT1 is a protein involved in regulating the function of signaling receptors internalized through the clathrin pathway and can be used as a diagnostic tool for defining the endocytic pathway of a receptor. (duke.edu)
  • The specificity of the GIT1 effect is not related to the type of G protein to which a receptor couples, but rather to the endocytic route it uses. (duke.edu)
  • These results suggest that NO contributes to L-LTP by stimulating guanylyl cyclase and cGMP-dependent protein kinase, which acts in parallel with PKA to increase phosphorylation of the transcription factor CREB. (jneurosci.org)
  • In a separated experiment, cavernosal strips from New Zealand white rabbits were harvested for organ bath study and the relaxation effect of beta-lapachone on phenylephrine-induced contracted strips was evaluated and compared with sodium nitroprusside, zaprinast, metformin, and aminoimidazole carboxamide ribonucleotide (AICAR). (korea.ac.kr)
  • ADAM12/syndecan-4 signaling promotes beta 1 integrin-dependent cell spreading through protein kinase Calpha and RhoA. (umassmed.edu)
  • The G protein-coupled receptor (GPCR) kinases (GRKs) phosphorylate and desensitize agonist-occupied GPCRs. (duke.edu)
  • Classic fatty acid metabolism involves the breakdown of fatty acids by beta-oxidation within the mitochondria. (biomedcentral.com)
  • Salt-inducible kinase 3 (SIK3) plays a crucial role in various aspects of metabolism. (elifesciences.org)
  • The response of a B cell to antigen is dependent on the surface expression of a clonotypic B-cell receptor complex (BCR) consisting of membrane-bound Ig and disulfide-linked heterodimers of Ig alpha/beta. (nih.gov)
  • Here we present evidence that heterodimers of Ig alpha and Ig beta efficiently induced apoptosis while homodimers of either chain did not. (nih.gov)
  • Apoptosis was associated with the inductive tyrosine phosphorylation of a very restricted set of proteins including the tyrosine kinase Syk. (nih.gov)
  • This study is to investigate the role of p38 mitogen-activated protein kinase (p38MAPK) in tert -butyl hydroperoxide ( t BHP)-induced apoptosis of human trabecular meshwork (iHTM) cells. (molvis.org)
  • The Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) is reported to cause apoptosis of infected cells and several of its proteins including the 3a accessory protein, are pro-apoptotic. (nih.gov)
  • The potential functional consequences of PKC beta-induced retinoblastoma phosphorylation could include enhanced E2 promoter binding factor transcriptional activity and increased VEGF -induced endothelial cell proliferation. (bvsalud.org)
  • Simoneau, B., Houle, F. and Huot, J. (2012) Regulation of Endothelial Permeability and Transendothelial Migration of Cancer Cells by Tropomyosin-1 Phosphorylation. (scirp.org)
  • Human umbilical vein endothelial cells (HUVECs) were treated with beta-lapachone. (korea.ac.kr)
  • Although HMG proteins do not possess intrinsic transcriptional activity, they are called architectural transcription factors because they modulate the transcription of their target genes by altering the chromatin structure at the promoter and/or enhancers 15 . (nature.com)
  • Solution structure and functional investigation of human guanylate kinase reveals allosteric networking and a crucial role for the enzyme in cancer. (mpg.de)
  • Several viruses require lysosomal cathepsins to cleave structural proteins and thus depend on functional GlcNAc-1-phosphotransferase. (stanford.edu)
  • We have previously identified NFAT (nuclear factor of activated T-cells) as a key regulator of insulin gene transcription in pancreatic β-cells that is activated by the calcium/calmodulin-dependent protein phosphatase 2B (calcineurin) in response to increased [Ca 2+ ] i ( 10 ). (diabetesjournals.org)
  • However, Ig alpha, Ig beta, and most of the other receptor chains that contain ITAMs, including CD3 epsilon, CD3 gamma, TCR zeta, and Fc epsilon Rl gamma, are found as components of multimeric and heterogeneous complexes. (nih.gov)
  • Many types of opioid receptors (e.g., μ , κ , δ ) exist in the nervous system, and they are all typical inhibitory G protein-coupled receptors (GPCRs) [ 30 ]. (hindawi.com)
  • Agonist stimulation of GABA B receptors enhances the phosphorylation of Akt (Thr-308) and enhances the phosphorylation of GSK-3α (Ser-21)/β (Ser-9) in both HEK-293T cells expressing GABA B receptors and rat hippocampal slices. (biomedcentral.com)
  • E7 from human papil omavirus type 16 cooperate to cancer: the European prospective investigation into doi:10.1093/carcin/bgp321 PMID:20047954 target the PDZ protein Na/H exchange regulatory cancer and nutrition study. (who.int)
  • PMID:21724855 phosphorylation and stabilization. (who.int)
  • Proteína serina-treonina cinasa que cataliza la FOSFORILACIÓN de las PROTEÍNAS I-KAPPA B. Esta enzima activa también el factor de transcripción NF-KAPPA B y está constituida por subunidades catalíticas alfa y beta, que son proteina cinasas, y gamma, una subunidad reguladora. (bvsalud.org)
  • The phosphate group does not act as a docking site for coSMAD, but rather the phosphorylation opens up an amino acid stretch allowing interaction. (wikipedia.org)
  • A synthesized peptide derived from human PKA alpha/beta CAT, corresponding to a region within N-terminal amino acids. (thermofisher.com)
  • Albuterol sulfate, chemically known as (1,3-benzenedimethanol, α'-[[(1,1dimethylethyl) amino] methyl]-4-hydroxy, sulfate (2:1)(salt), (±)- is a relatively selective beta 2 -adrenergic bronchodilator. (rxlist.com)
  • Another effect of GSK3-beta over-expression was the impeded transport of synaptically active a-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors to the cell surface after glycine stimulation, indicating negative effects on long-term potentiation and cognition. (europa.eu)
  • I-kappa B Kinase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (uchicago.edu)
  • Insights into open/closed conformations of the catalytically active human guanylate kinase as investigated by small-angle X-ray scattering. (mpg.de)
  • Beta-hCG and alpha-fetoprotein have proved to be useful markers for ovarian germ cell tumors. (medscape.com)
  • Zerradi, M. , Houle, F. and Huot, J. (2015) Regulation of Breast Cancer Progression by Phosphorylation of the Tumor Suppressor Tropomyosin-1 Alpha. (scirp.org)
  • The following product was used in this experiment: PKA C alpha/beta Polyclonal Antibody from Thermo Fisher Scientific, catalog # PA5-115763, RRID AB_2900398. (thermofisher.com)
  • Not only GSK3-beta, but also its isoenzyme GSK3-alpha were shown to increase tau phosphorylation. (europa.eu)
  • More than 10 different SH2-domain-containing molecules have been shown to bind to different autophosphorylation sites in the PDGF-alpha and -beta receptors. (loinc.org)
  • PDGF-alpha receptors are expressed in oligodendrocyte progenitor cells and PDGF beta receptors are expressed on neurons. (loinc.org)
  • While it is recognized that beta 2 -adrenergic receptors are the predominant receptors on bronchial smooth muscle, recent data indicate that there is a population of beta 2 -receptors in the human heart which comprise between 10% and 50% of cardiac beta-adrenergic receptors. (theodora.com)
  • However, the order of events and the precise function of high-mobility group proteins during transcription initiation remain unclear. (nature.com)
  • The cilia are composed of three main sections, the axoneme which performs the sensory or movement function, the transition zone which likely contains over 100 proteins which function to anchor the cilia and regulate transport to and from the cilia , and the basal body which is a centriole that functions as a tubulin organizing center to form the cilia . (xenbase.org)
  • A study by White et al (2009) found that psychosine's cytotoxic effects on oligodendroglia and Schwann cells was mediated through disruption of the architecture and composition of lipid rafts (cell membrane regions characterized by high cholesterol and sphingolipid concentration), followed by altered protein kinase C (PKC) function. (medscape.com)
  • The N-terminal region of centrosomal protein 290 (CEP290) restores vision in a zebrafish model of human blindness. (xenbase.org)
  • Detects human, mouse, and rat p38 beta in Western blots. (rndsystems.com)
  • Detection of Human, Mouse, and Rat p38 beta by Western Blot. (rndsystems.com)
  • PVDF membrane was probed with 0.2 µg/mL of Mouse Anti-Human/Mouse/Rat p38 beta Monoclonal Antibody (Catalog # MAB5885) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF007 ). (rndsystems.com)
  • Western blot shows Recombinant Human p38 beta, Recombinant Human p38? (rndsystems.com)
  • Have you used Human/Mouse/Rat p38 beta Antibody? (rndsystems.com)
  • 1 H, 13 C and 15 N resonance assignment of human guanylate kinase. (mpg.de)
  • Daneshpajooh M, Bacos K, Bysani M, Bagge A, Ottosson Laakso E, Vikman P, Eliasson L, Mulder H, Ling C. HDAC7 is overexpressed in human diabetic islets and impairs insulin secretion in rat islets and clonal beta cells. (lu.se)