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  • regulators
  • Expression of cell cycle regulators p27Kip1 and cyclin E, alone and in combination, correlate with survival in young breast cancer patients. (springer.com)
  • breast
  • Donnellan R, Kleinschmidt I, Chetty R. Cyclin E immunoexpression in breast ductal carcinoma: pathologic correlations and prognostic implications. (springer.com)
  • repression
  • To distinguish whether transcriptional repression is due to phosphorylation of TBP, hTAF I 110 or both, SL1 was purified from two HeLa cell lines that express either full‐length or the core domain of TBP only. (embopress.org)
  • subsequent
  • NEDD1 phosphorylation promotes subsequent targeting of the gamma-tubulin ring complex (gTuRC) to the centrosome, an important step for spindle formation. (nih.gov)
  • Cdk5
  • synGAP is phosphorylated at Ser-773 and Ser-802 in the PSD fraction, and its phosphorylation by CDK5 and CaMKII is differentially regulated by activation of NMDA-type glutamate receptors in cultured neurons. (nih.gov)
  • sites
  • EL2/3 and EL5/6 are products of elastase-mediated proteolysis at 2 distinct sites in the amino terminus of cyclin E. EL-4 is generated via translation of an alternative downstream methionine. (aacrjournals.org)
  • We report the identification of >14,000 different phosphorylation events, more than half of which, to our knowledge, have not been described in the literature, along with relative quantitative data for the majority of these sites. (uniprot.org)
  • creates its own docking sites on PRC1 and KIF20A/MKLP2 by mediating phosphorylation of sites subsequently recognized by the POLO box domains. (nih.gov)