Checkpoint Kinase 2Cell Cycle ProteinsProtein-Serine-Threonine KinasesDNA DamageGenes, cdcProtein KinasesMitosisG2 PhasePhosphorylationAtaxia Telangiectasia Mutated ProteinsCell CycleS PhaseCell Cycle CheckpointsSaccharomyces cerevisiae ProteinsDNA ReplicationHydroxyureaS Phase Cell Cycle CheckpointsSpindle ApparatusM Phase Cell Cycle CheckpointsNuclear ProteinsSaccharomyces cerevisiaeDNA-Binding ProteinsSerineSchizosaccharomyces pombe Proteinscdc25 PhosphatasesSchizosaccharomycesIntracellular Signaling Peptides and ProteinsMutationPhosphoproteinsFungal ProteinsEnzyme ActivationMolecular Sequence DataKinetochoresAmino Acid SequenceCell LineSignal TransductionCDC2 Protein KinaseDNA RepairNocodazoleTyrosineTumor Suppressor ProteinsDNA, FungalMethyl MethanesulfonateHeLa CellsProtein BindingG1 PhaseUltraviolet RaysPhosphoserineSecurinTumor Suppressor Protein p53AnaphaseCyclin BProtein-Tyrosine KinasesEnzyme InhibitorsCell Line, TumorThreonineG2 Phase Cell Cycle CheckpointsModels, BiologicalOxidative PhosphorylationGenomic InstabilityCells, CulturedSaccharomycetalesExodeoxyribonucleasesMad2 ProteinsCyclin-Dependent KinasesGenes, FungalProtein Kinase CGene Expression Regulation, FungalGamma RaysCarrier ProteinsApoptosisBlotting, WesternHistonesPhosphopeptidesCyclic AMP-Dependent Protein KinasesCyclin-Dependent Kinase 2Replication Protein APhosphotyrosineRecombinant Fusion ProteinsCell DivisionNucleic Acid Synthesis InhibitorsChromosomal Proteins, Non-HistoneReplication Protein CTransfectionStaurosporineProto-Oncogene Proteins c-aktRepressor ProteinsGene DeletionCdc20 ProteinsKineticsPhosphothreonineProtein Structure, TertiaryProtein Processing, Post-TranslationalMitogen-Activated Protein KinasesCyclin-Dependent Kinase Inhibitor p21Phosphoprotein PhosphatasesChromosome SegregationTranscription FactorsImmunoblottingProto-Oncogene Proteins