• Additionally, FLCN phosphorylation (on Serines 62 and 73) fluctuates throughout the cell cycle and peaks during the G2/M phase in cells treated with nocodazole. (unizg.hr)
  • These findings suggest that the tumor suppression function of FLCN may be linked to its impact on the cell cycle and that FLCN phosphorylation is important for this activity. (unizg.hr)
  • The phosphorylation of inositol headgroups of phosphatidylinositol at up to three sites leads to a multitude of PL products that are potently bioactive and highly transient. (asbmb.org)
  • The dissociation of vimentin filaments via phosphorylation in nondividing cells results in a cytoskeletal contraction (via the myosin light chain) that directs LDL droplets to the mitochondria where cholesterol is exposed to its side-chain cleavage enzyme, thus increasing steroid biosynthesis. (stem-cell-marker.com)
  • There were several important features of three minutes, whereas in rats, are mediated via phosphorylation results in a small risk of prostate cancer has been used successfully in therapy. (salganyc.org)
  • Therefore, to reveal the role of APP phosphorylation at Thr, careful analysis for the phosphorylation state of both APP and the APP metabolic fragments in the brain are described here. (pilifysopysy.tk)
  • Finally, we analysed the effect of the inhibition of IκBα degradation on glutamate-induced toxicity by using BAY 11-7082, a selective inhibitor of IκBα phosphorylation. (elsevier.com)
  • Utilizamos diversas técnicas de biología molecular y estructural, con especial énfasis en la cristalografía de rayos X. Nuestras principales líneas de investigación son: control de la replicación de ADN, transferencia horizontal de genes, empaquetamiento del ADN en los virus, regulación de la transcripción y maquinaria de replicación viral. (sebbm.es)