• Phosphoric monoester hydrolases (or phosphomonoesterases) are enzymes that catalyse the hydrolysis of O-P bonds by nucleophilic attack of phosphorus by cysteine residues or coordinated metal ions. (wikipedia.org)
  • Phosphoric Monoester Hydrolases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (rush.edu)
  • This graph shows the total number of publications written about "Phosphoric Monoester Hydrolases" by people in this website by year, and whether "Phosphoric Monoester Hydrolases" was a major or minor topic of these publications. (rush.edu)
  • phosphoric monoester hydrolase) inhibitor that interferes with the action of alkaline phosphatase (EC 3.1.3.1). (ebi.ac.uk)
  • Discovery of the First in Vivo Active Inhibitors of the Soluble Epoxide Hydrolase Phosphatase Domain. (nih.gov)
  • Although the physiological role of the C-terminal hydrolase domain is well-investigated, little is known about its phosphatase activity, located in the N-terminal phosphatase domain of sEH (sEH-P). Herein we report the discovery and optimization of the first inhibitor of human and rat sEH-P that is applicable in vivo. (nih.gov)
  • AP is a subclass of phosphomonoesterase or phosphoric monoester hydrolase enzymes that catalyze ester (C-O-P) bond cleavage, sharing characteristic alkaline pH optima. (frontiersin.org)