OrganismsChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentInformation Science
PhosphoglucomutasePhosphotransferases (Phosphomutases)GlucosephosphatesElectrophoresis, Starch GelGalactoseGlucose-6-PhosphateGlucose-6-Phosphate IsomeraseUridine Diphosphate GlucoseParamecium tetraureliaLithium CompoundsGlucose-1-Phosphate AdenylyltransferaseUTP-Glucose-1-Phosphate UridylyltransferasePhosphogluconate DehydrogenaseGluconacetobacter xylinusRibosemonophosphatesMolecular Sequence Data
Facilitated by the enzyme phosphoglucomutaseEnzyme phosphoglucomutaseGlycolysisFructose 1,6-bisphosphatePGM3PyruvateGlycogen phosphorylaseGlycolyticGlyceraldehydeEnzymesMetabolicPathwayGlucose is convertedLiverProcessMoleculesMitochondriaIntermediateActionBackCellStepGlucose 1-phosphaEnzyme convertsMetabolismSubstrateTransfer
Facilitated by the enzyme phosphoglucomutase1
  • This conversion facilitated by the enzyme phosphoglucomutase, which transfers the phosphate group from the sixth carbon of G6P to the first carbon, resulting in the formation of G1P. (classicbiotech.com)
Enzyme phosphoglucomutase3
  • The second enzyme, phosphoglucomutase converts glucose 1-phosphate into glucose 6-phosphate. (pediaa.com)
  • Glucose-6-phosphate is isomerised into fructose,6-phosphate by the enzyme phosphoglucomutase. (byjus.com)
  • It cannot travel down many metabolic pathways and must be interconverted by the enzyme phosphoglucomutase in order to become glucose 6-phosphate. (ecmdb.ca)
Glycolysis11
  • The Cori cycle (also known as the lactic acid cycle), named after its discoverers, Carl Ferdinand Cori and Gerty Cori, is a metabolic pathway in which lactate, produced by anaerobic glycolysis in muscles, is transported to the liver and converted to glucose, which then returns to the muscles and is cyclically metabolized back to lactate. (wikipedia.org)
  • From an intuitive perspective, gluconeogenesis reverses both glycolysis and fermentation by converting lactate first into pyruvate, and finally back to glucose. (wikipedia.org)
  • The glucose 6-phosphate that is formed during the phosphoglucomutase process can be absorbed into glycolysis or a different pathway, such as the pentose phosphate pathway. (microbiologynote.com)
  • Glucose enters the cell and undergoes two-step conversion to fructose-6P (fructose-6-phosphate), after which approximately 95% of it proceeds to glycolysis and 3-5% of it is converted to glucosamine-6P (glucosamine-6-phosphate) by the enzyme GFAT (glutamine:fructose-6-phosphate amidotransferase), utilizing glutamine that enters the cell. (biomedcentral.com)
  • The essence of glycolysis is that glucose is converted into two molecules of pyruvate in the cytoplasm of all cells, with no oxygen required. (elizabethfilips.com)
  • This means that NADH+H+ needs to be recycled, and this happens by converting pyruvate (which is no longer needed in these anaerobic cells) into lactate, the reduction of which oxidises NADH+H+ back into NAD which can be used in further glycolysis reactions. (elizabethfilips.com)
  • Phosphofructokinase is the enzyme which converts fructose 6-phosphate into fructose 1,6-bisphosphate - it is the rate limiting step in glycolysis and is therefore very important. (elizabethfilips.com)
  • PGM1 inhibits hepatocellular carcinoma cell (HCC) proliferation and growth by utilizing sufficient extracellular glucose to convert glycogen, while deletion of the PGM1 gene inhibits glycogen synthesis and leads to glycolysis of additional glucose, thus promoting tumor cell proliferation and growth [ 15 ]. (biomedcentral.com)
  • Glycolysis is the metabolic process that converts glucose into pyruvic acid. (byjus.com)
  • Triose-phosphate isomerase converts dihydroxyacetone phosphate into glyceraldehyde 3-phosphate which is the substrate in the successive step of glycolysis. (byjus.com)
  • After the end of the glycolysis pathway the pyruvate converts into acetyl-CoA which later participates in Krebs cycle process. (lambdageeks.com)
Fructose 1,6-bisphosphate2
  • The other ATP molecule transfers a phosphate group to fructose 6-phosphate and converts it into fructose 1,6-bisphosphate by the action of the enzyme phosphofructokinase. (byjus.com)
  • The enzyme aldolase converts fructose 1,6-bisphosphate into glyceraldehyde 3-phosphate and dihydroxyacetone phosphate, which are isomers of each other. (byjus.com)
PGM35
  • The PGM3 gene provides instructions for making an enzyme called phosphoglucomutase 3 (PGM3). (medlineplus.gov)
  • The PGM3 enzyme converts a molecule called N-acetylglucosamine-6-phosphate into a different molecule called N-acetylglucosamine-1-phosphate. (medlineplus.gov)
  • Susceptibility to infections, without concomitant hyper-IgE, reported in 1976, is caused by hypomorphic mutation in the phosphoglucomutase 3 (PGM3) gene. (medlineplus.gov)
  • This is then converted to GlcNAc-1P (N-acetylglucosamine 1-phosphate) by PGM3/AGM1 (phosphoglucomutase) and further to UDP-GlcNAc (uridine diphosphate N-acetylglucosamine) by UAP/AGX1 (UDP-N-acetylhexosamine pyrophosphorylase), utilizing UTP from the nucleotide metabolism pathway. (biomedcentral.com)
  • Within the UDP-GlcNAc salvage pathway, Nagk phosphorylates GlcNAc to GlcNAc-6-P, that is changed into GlcNAc-1-P by phosphoglucomutase 3 (Pgm3, Fig. S4B) (Berger et al. (exposed-skin-care.net)
Pyruvate6
  • Lactic acid fermentation converts pyruvate to lactate by lactate dehydrogenase. (wikipedia.org)
  • Under anaerobic conditions in muscle pyruvate is converted into? (flashcardmachine.com)
  • Lactate leaves these cells (usually erythrocytes and muscle cells) and is converted back into pyruvate in the liver. (elizabethfilips.com)
  • In the liver, lactate is converted back into pyruvate. (elizabethfilips.com)
  • To be available for TAG synthesis, carbons from sucrose must first be converted to pyruvate through cytosolic or plastidic glycolytic pathways and at some point be imported into the plastid to yield acetyl-coenzyme A (CoA) which feeds fatty acid (FA) synthesis with carbon backbones. (biomedcentral.com)
  • As only though this process the pyruvate converts into acetyl-CoA and acetyl-CoA is the only component which can undergoes Krebs cycle procedure. (lambdageeks.com)
Glycogen phosphorylase1
Glycolytic2
Glyceraldehyde1
  • Alternately Deoxyribose 5-phosphate can be converted to D-glyceraldehyde-3 phosphate that can then feed into the pentose phosphate pathway. (hmdb.ca)
Enzymes3
  • Dextrins and maltose are converted to glucose by enzymes in the border of the intestinal brush (the microvilli that resemble fingers of the epithelial cells in the intestinal tract, which dramatically increase the surface area of the surface of the intestine). (microbiologynote.com)
  • Mutases are a class of isomerases, enzymes that convert stereoisomers and the structural and positional isomers. (microbiologynote.com)
  • Thus the debranching enzymes, transferase and α-1,6- glucosidase converts the branched glycogen structure into a linear one, paving the way for further cleavage by phosphorylase. (wikidoc.org)
Metabolic1
  • Cellular respiration cycle is a combination of some metabolic processes that occurs in living cells, which converts food or nutrients into energy units (ATP) and releases different by-products from it. (lambdageeks.com)
Pathway2
  • In pathway III, after uptake and phosphorylation by the PTS, trehalose-6-phosphate phosphorylase (trePP) forms beta-glucose-1-phosphate and glucose-6-phosphate, and beta-phosphoglucomutase converts glucose-1-phosphate to glucose-6-phosphate. (lbl.gov)
  • This pathway occurs in the liver, beginning with cholesterol being converted to 7a-hydroxycholesterol through the enzyme cholesterol-7-alpha-monooxygenase, after being transported into the liver cell. (smpdb.ca)
Glucose is converted1
  • That glucose is converted into a storage carbohydrate known as glycogen in a process called glycogenesis. (pediaa.com)
Liver2
  • Glycogenesis is the process by which glucose molecules converted into glycogen for storage in the liver and muscles. (classicbiotech.com)
  • Glycogenesis occurs primarily in the liver and muscles, where glucose converted into glycogen through a series of enzymatic reactions. (classicbiotech.com)
Process1
  • Phosphoglucomutase is essentially the same mechanism as phosphoglycerate Mutase (p. 537) Both involve an intermediate bisphosphate, as well as being transiently phosphorylated during every catalytic process. (microbiologynote.com)
Molecules1
  • This intricate mechanism involves a series of enzymatic reactions that convert glucose molecules into glycogen, ensuring a steady supply of energy during periods of fasting or increased physical activity. (classicbiotech.com)
Mitochondria1
  • In the mitochondria of the cell, sterol 26-hydroxylase converts 3a,7a-dihydroxy-5b-cholestane to 3a,7a,26-trihydroxy-5b-cholestane, which is then converted to 3a,7a-dihydroxy-5b-cholestan-26-al by the same enzyme used in the previous reaction. (smpdb.ca)
Intermediate1
  • Must be converted to PEP to form a high energy intermediate that is able to synthesize. (flashcardmachine.com)
Action1
Back1
Cell2
  • Glucosamine entering the cell is also converted to glucosamine-6-phosphate using GNK (GlcNAc kinase). (biomedcentral.com)
  • GNA1/GNPNAT1 (glucosamine-6-phosphate N-acetyltransferase) then converts glucosamine-6P (which can also be made by glucosamine entering the cell) into GlcNAc-6P (N-acetylglucosamine-6-Phosphate), also utilizing acetyl-CoA that is made from fatty acid metabolism. (biomedcentral.com)
Step1
  • Glutamine fructose-6-phosphate amidotransferase (GFAT) converts F6P and glutamine to glucosamine-6-phosphate and glutamate in the rate-limiting step of HBP [ 6 ]. (biomedcentral.com)
Glucose 1-phospha5
  • The released glucose-1-phosphate is then converted to GLUCOSE-6-PHOSPHATE by PHOSPHOGLUCOMUTASE before entering GLYCOLYSIS . (bvsalud.org)
  • Dr. Ampaw completed her master's of chemistry at Dalhousie University, where she researched inhibiting β-phosphoglucomutase, a protein that converts glucose-1-phosphate to glucose-6-phosphate. (themedium.ca)
  • In glycogenolysis, phosphoglucomutase catalyses the conversion of glucose-1-phosphate to glucose-6-phosphate (transfer of phosphate group from one position to another in the same substance) (glycogen is converted to glucose for energy to be released quickly). (microbiologynote.com)
  • Phosphoglucomutase is an enzyme that can transfer the phosphate group on the α-D-glucose monomer forward from the 1-position to the 6-position or reversely transfer from the 6-position to the 1-position, and promote the glucose-1-phosphate and glucose-6-phosphate Transform each other. (medchemexpress.cn)
  • Phosphoglucomutase (PGM) catalyzes the reversible interconversion of Nav1.2 Inhibitor Species glucose 6-phosphate (G6P) and glucose 1-phosphate (G1P). (amparinhibitor.com)
Enzyme converts1
  • The PGM3 enzyme converts a molecule called N-acetylglucosamine-6-phosphate into a different molecule called N-acetylglucosamine-1-phosphate. (medlineplus.gov)
Metabolism2
Substrate1
  • Through the formation of sucrose the cytosolic PGM (cPGM) is essential as it converts G6P into G1P, which is the substrate for the UDPglucose pyrophosphorylase.Also in the dark, when the photosynthetic driven export of carbon from the chloroplast is absent, the formation of sucrose is dependent on cPGM activity [5,6]. (amparinhibitor.com)
Transfer1
  • The haloacid dehalogenase-like hydrolase superfamily is a large group of enzymes, whose members are involved not only in the enzymatic cleavage by nucleophilic substitution of carbon-halogen bonds (C-halogen), but also in a variety of hydrolytic enzyme activities including phosphoglucomutase (CO-P hydrolysis and intramolecular phosphoryl transfer) reactions, ATPases (PO-P cleavage), dehalogenases (C-Cl cleavage), phosphonatase (C-P), and phosphatase (CO-P) (Lahiri et al. (springeropen.com)